Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining.

    David Christian, professor of history at San Diego State University, surveys the past at all possible scales, from conventional history, to the much larger scales of biology and geology, to the universal scales of cosmology.

    Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    And with the advent of modern science, great minds have turned to testing and experimentation rather than mere thought as a way of approaching and grappling with some of the universe's most pressing and vexing dilemmas. So what is our latest picture of some of the most inexplicable features of the universe? What still remains to be uncovered? What are some of the next avenues of exploration for today's chemists, physicists, biologists, and astronomers? Pondering the answers to these and other questions is a great way to appreciate the grandeur and complexity of the world around you, better understand and discuss news and developments in science, and spark further interest in some of science's many exciting areas of study. "We know a lot about the universe. But there's even more that we don't know,"says astrophysicist and Professor Neil deGrasse Tyson, director of the Hayden Planetarium, an award-winning lecturer, and one of the world's foremost experts on the secrets of the universe. And his course The Inexplicable Universe: Unsolved Mysteries is the perfect gateway into this mind-bending and eye-opening subject. Each of these six self-contained lectures is a marvelous journey to the frontiers of the known (and unknown) universe and introduces you to tantalizing questions being addressed by the world's top scientists. Undeniably engaging and fascinating, this lecture series is a wonderful entrée to scientific pursuits that lie at the very heart of the history and nature of our universe. An Informed Scientific Conversation Central to The Inexplicable Universe is the way it takes you deep into hidden layers of the universe in a manner that is extremely accessible. Rather than a stern lecture given before a podium complete with confusing mathematics, Professor Tyson's lectures have the feel of an informed conversation that manages to be both thorough and easy to grasp. With each of the inexplicable mysteries he lays bare for you, Professor Tyson introduces you to the history behind it, lays out the science that has helped us grasp it, explains what researchers have discovered to date, and reveals what we have yet to discover. And while the topics explore subjects in everything from quantum mechanics to cosmology to string theory, you'll never feel overwhelmed by what you're learning. In fact, you're more likely to find yourself intrigued by just how much we know-and curious about what the near future will possibly reveal. Explore Fascinating Territory So what territory will you chart in this course? Here are some of the inexplicable ideas you'll investigate in these lectures. Neutrinos: Discovered in 1956, these fast-moving, ghostlike particles are made in abundance in the sun's core. They hardly interact with matter; it takes a light-year's worth of lead (5.8 trillion miles) to stop a neutrino. Not only that, but 65 billion neutrinos pass through every centimeter of your body that's facing the sun every second of every day. String theory: This astounding theory offers the hope of unifying all the particles and forces of physics. In the past several decades since the dawn of string theory, it's been imagined that all the fundamental particles we see and measure are just the manifestation in our dimension of strings vibrating in higher dimensions and at different frequencies. Quantum foam: This idea posits that when the fabric of space and time is so tightly curved on itself, space-time is less a smooth curve and more like the froth on a latte. In this state of matter and energy, quantum fluctuations can spawn entire universes, each with slightly different laws of physics within them! In addition, you'll also get a peek at what it would be like to travel through a black hole, ponder the possibility that life on Earth originated in debris from Mars, probe the supposed existence of multiple universes, and even imagine the possible end of the universe itself. A One-on-One Chat with a Renowned Science Educator Professor Tyson is renowned throughout the scientific community and the media for his vast knowledge, his penetrating insights, and his amazing ability to make even the most intimidating areas of science accessible, engaging, and-most of all-enjoyable. He brings the same inviting tone and sharp intellect to The Inexplicable Universe as he does to his range of media appearances on popular television programs. Due to its unique subject matter The Inexplicable Universe takes a highly visual approach. Many of the fascinating subjects in the course, such as black holes, string theory, and multiple universes are best demonstrated visually and Professor Tyson's lectures feature expertly crafted computer animations, explanatory diagrams, high resolution photographs, and other instructive visual elements. In order to better explain to you some of the grand, intricate ideas being discussed, Professor Tyson personally interacts with many of these animations and graphics using greenscreen technology. Please note that, due to the highly visual nature of The Inexplicable Universe, the course does not come with a guidebook. We did not believe a simple book could adequately convey the information in the course, and rather than make a guidebook that did not do the course justice, we decided to not offer one. However, we believe that you will be very excited by how we produced this course and will find it to be an enriching and fulfilling experience in your educational journey.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    News of both the Ice Man's discovery and his age, which was put at over five thousand years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative of a man who died thousands of years ago?In The Seven Daughters of Eve, he gives us a firsthand account of his research into a remarkable gene, which passes undiluted from generation to generation through the maternal line. After plotting thousands of DNA sequences from all over the world, Sykes found that they clustered around a handful of distinct groups. Among Europeans and North American Caucasians, there are, in fact, only seven. This conclusion was staggering: almost everyone of native European descent, wherever they may live throughout the world, can trace their ancestry back to one of seven women, the Seven Daughters of Eve.Naming them Ursula, Xenia, Helena, Velda, Tara, Katrine, and Jasmine, Sykes has created portraits of their disparate worlds by mapping the migratory patterns followed by millions of their ancestors. In reading the stories of these seven women, we learn exactly how our origins can be traced, how and where our ancient genetic ancestors lived, and how we are each living proof of the almost indestructible strands of DNA, which have survived over so many thousands of years. Indeed, The Seven Daughters of Eve is filled with dramatic stories: from Sykes's identification, using DNA samples from two living relatives, of the remains of Tsar Nicholas and Tsaress Alexandra, to the Caribbean woman whose family had been sold into slavery centuries before and whose ancestry Sykes was able to trace back to the Eastern coast of central Africa. Ultimately, Sykes's investigation reveals that, as a race, what humans have in common is more deeply embedded than what separates us.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    His book includes essays on Sudan, India, Cuba, Germany and California. In each piece, there is a central image as the key to unlocking the personality of a place.

    24 Lectures 1 Writing the World: The Mapmakers Craft 2 The Problem with Geographical Determinism 3 Anthropocene: The Age of Human Impact 4 Climate Change and Civilization 5 Global Land Change 6 The End of Global Population Growth 7 The Agricultural Puzzle 8 Disease Geography 9 Political Ecology 10 Economic Geography: Globalization Origins 11 The Columbian Exchange 12 Uneven Development and Global Poverty 13 The New Global Economy 14 Restless Humanity: The Migration Conundrum 15 Urbanization: The Rise of New World Cities 16 Geography of Language 17 Understanding Cultural Geography 18 The Importance of Place 19 Cultural Commodification 20 Culture, Power, and the Politics of Meaning 21 The Geopolitical Imagination 22 Regionalism and the Rise of New States 23 Supranationalism: Taking on Big Problems 24 Future Geographies

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    For example, the matter that comprises all stars, planets, and living things turns out to be just a fraction of what actually exists. Moreover, we think that we control our actions, but data analytics can predict, with astonishing accuracy, when we will wake up, what we will buy, and even whom we will marry.The quest to pin down what's real and what's illusory is both philosophical and scientific, a metaphysical search for ultimate reality that goes back to the ancient Greeks. For the last 400 years, this search has been increasingly guided by scientists, who create theories and test them in order to define and redefine reality. And we have developed the power to alter our own reality in major ways - to defeat diseases, compensate for disabilities, and augment our intellect with computers. Where is that trend going?Experience the thrill of this exciting quest in 36 wide-ranging lectures that touch on many aspects of the ceaseless search for reality. From the birth of the universe to brain science, discover that separating the real from the illusory is an exhilarating intellectual adventure.Scientists and philosophers are not alone in grappling, at an intellectual level, with reality. Some of the most accessible interpretations are by painters, novelists, filmmakers, and other artists whose works not only draw on the latest discoveries but also sometimes inspire them. Explore examples such as Alice in Wonderland, pointillism, cubism, surrealism, and reality TV.And since dealing with reality is an experience we all share, this course is designed for people of all backgrounds.

    Paradoxical portraits of seven neurological patients, including a surgeon consumed by the compulsive tics of Tourette's syndrome unless he is operating; an artist who loses all sense of color in a car accident, but finds new creative power in black & white; & others.

    But is old age all doom and gloom?Not at all! While it's true that some functions in the aging brain decline, neuroscientists have discovered that many other brain functions remain stable - or even improve - as we age. Furthermore, nurture plays as significant a role as nature, and there are a number of strategies you can implement to stave off declining brain function, including:Incorporating physical activity into your routineEating a healthy dietMaintaining a vibrant social lifeReducing your stressThe science behind the aging brain tells a fascinating - and often counterintuitive - story. Is "aging" a disease or merely a natural occurrence that produces disease-like symptoms? If humans are biologically programmed to survive and thrive, why do we age at all? Is it possible (or even desirable) to "cure" aging altogether?Delve into these questions and more in The Aging Brain. Taught by a neuroscientist and award-winning professor at the University of Michigan, these 12 eye-opening lectures will give you a wealth of new insights into what happens to the brain over time - as well as strategies to mitigate the effects of aging and enhance your quality of life into old age.With a mix of scientific research and practical applications, Professor Polk brings cutting-edge science to life. He takes you down to the cellular and even molecular levels of the brain to show you why certain functions decline, how some aspects of brain aging are under genetic control, and what you can do to prolong your health and keep your mind sharp. Aging affects us all, but you have some control over how it affects you.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    (Great Courses, #660)