It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    The job: to delve into the psyche of convicted men and women to try to understand what lies behind their often brutal actions. Follow in the footsteps of Kerry Daynes, one of the most sought-after forensic psychologists in the business and consultant on major police investigations. Kerry's job has taken her to the cells of maximum-security prisons, police interview rooms, the wards of secure hospitals and the witness box of the court room. Her work has helped solve a cold case, convict the guilty and prevent a vicious attack. Spending every moment of your life staring into the darker side of life comes with a price. Kerry's frank memoir gives an unforgettable insight into the personal and professional dangers in store for a female psychologist working with some of the most disturbing men and women.

    Full of extraordinary facts and astonishing stories, The Body: A Guide for Occupants is a brilliant, often very funny attempt to understand the miracle of our physical and neurological make up.A wonderful successor to A Short History of Nearly Everything, this book will have you marvelling at the form you occupy, and celebrating the genius of your existence, time and time again.

    They stood up and spoke out when no one else would. They broke the mould in art, music and literature. Each of them fought, in their own way, for change. Encompassing artists, politicians, activists, reporters and heads of state from past and present, A History of the World in 21 Women celebrates the lives, struggles and achievements of women who have had a profound impact on the shaping of our world. Jenni's 21 are: Joan of Arc, Artemesia Gentileschi, Angela Merkel, Benazir Bhutto, Hillary Clinton, Coco Chanel, Empress Dowager Cixi, Catherine the Great, Clara Schumann, Hatshepsut, Wangari Maathai, Golda Meir, Frida Kahlo, Toni Morrison, Margaret Atwood, Isabella of Castile, Cathy Freeman, Anna Politokovskaya, Sirimavo Bandaranaike, Madonna and Marie Curie.

    The childhood illness that left her bedridden for a year, which she was not expected to survive. A teenage yearning to escape that nearly ended in disaster. An encounter with a disturbed man on a remote path. And, most terrifying of all, an ongoing, daily struggle to protect her daughter--for whom this book was written--from a condition that leaves her unimaginably vulnerable to life's myriad dangers.Seventeen discrete encounters with Maggie at different ages, in different locations, reveal a whole life in a series of tense, visceral snapshots. In taut prose that vibrates with electricity and restrained emotion, O'Farrell captures the perils running just beneath the surface, and illuminates the preciousness, beauty, and mysteries of life itself.

    Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness.In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone.Along the way he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome--the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they're more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin to how we smell. The new goal of skin care will be to cultivate a healthy biome--and to embrace the meaning of "clean" in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process.Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

    In The Boy Who Was Raised as a Dog, he tells their stories of trauma and transformation through the lens of science, revealing the brain's astonishing capacity for healing. Deftly combining unforgettable case histories with his own compassionate, insightful strategies for rehabilitation, Perry explains what exactly happens to the brain when a child is exposed to extreme stress-and reveals the unexpected measures that can be taken to ease a child's pain and help him grow into a healthy adult. Through the stories of children who recover-physically, mentally, and emotionally-from the most devastating circumstances, Perry shows how simple things like surroundings, affection, language, and touch can deeply impact the developing brain, for better or for worse. In this deeply informed and moving book, Bruce Perry dramatically demonstrates that only when we understand the science of the mind can we hope to heal the spirit of even the most wounded child.

    It's the late 1960s and homosexuality has only just been legalised, and Jeremy Thorpe, the leader of the Liberal party, has a secret he's desperate to hide. As long as Norman Scott, his beautiful, unstable lover is around, Thorpe's brilliant career is at risk. With the help of his fellow politicians, Thorpe schemes, deceives, embezzles - until he can see only one way to silence Scott for good.The trial of Jeremy Thorpe changed our society forever: it was the moment the British public discovered the truth about its political class. Illuminating the darkest secrets of the Establishment, the Thorpe affair revealed such breath-taking deceit and corruption in an entire section of British society that, at the time, hardly anyone dared believe it could be true.

    She was repeatedly hospitalized in excruciating pain, but the doctors insisted it was a urinary tract infection and sent her home with antibiotics. Unable to get out of bed, much less attend class, Norman dropped out of college and embarked on what would become a years-long journey to discover what was wrong with her. It wasn't until she took matters into her own hands--securing a job in a hospital and educating herself over lunchtime reading in the medical library--that she found an accurate diagnosis of endometriosis.In Ask Me About My Uterus, Norman describes what it was like to have her pain dismissed, to be told it was all in her head, only to be taken seriously when she was accompanied by a boyfriend who confirmed that her sexual performance was, indeed, compromised. Putting her own trials into a broader historical, sociocultural, and political context, Norman shows that women's bodies have long been the battleground of a never-ending war for power, control, medical knowledge, and truth. It's time to refute the belief that being a woman is a preexisting condition.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.

    The genius of this biography is that it delves behind this image to reveal a life in which loss and heartache existed alongside rebellion and fierce ambition. Claire Harman seizes on a crucial moment in the 1840s when Charlotte worked at a girls' school in Brussels and fell hopelessly in love with the husband of the school's headmistress. Her torment spawned her first attempts at writing for publication, and the object of her obsession haunts the pages of every one of her novels--he is Rochester in Jane Eyre, Paul Emanuel in Villette. Another unrequited love--for her publisher--paved the way for Charlotte to enter a marriage that ultimately made her happier than she ever imagined. Drawing on correspondence unavailable to previous biographers, Harman establishes Brontë as the heroine of her own story, one as dramatic and triumphant as one of her own novels.

    Asking and answering some very specific questions about what goes on in her novels, he reveals the inner workings of their greatness.In twenty short chapters, each of which explores a question prompted by Austen's novels, Mullan illuminates the themes that matter most in her beloved fiction. Readers will discover when Austen's characters had their meals and what shops they went to; how vicars got good livings; and how wealth was inherited. What Matters in Jane Austen? illuminates the rituals and conventions of her fictional world in order to reveal her technical virtuosity and daring as a novelist. It uses telling passages from Austen's letters and details from her own life to explain episodes in her novels: readers will find out, for example, what novels she read, how much money she had to live on, and what she saw at the theater.Written with flair and based on a lifetime's study, What Matters in Jane Austen? will allow readers to appreciate Jane Austen's work in greater depth than ever before.

    National bestseller "Medicine Men" follows the beloved #1 bestselling "Heart in the Right Place". This is a collection of the most memorable moments from more than a dozen rural physicians who each practiced medicine for more than 50 years in the Southern Appalachian Mountains from 1930-2012. Hilarious, heroic, true stories of miracle cures, ghost dogs, and much madcap medical mayhem. Unimaginably funny and touching situations where men with nerves of steel and hearts of gold get stuck between a rock and a hard place in the Smoky Mountains. These men are saints who walk among us and Jourdan's father is one of them. Jourdan's work is often compared to James Herriot and Bill Bryson. This story collection is like "All Creatures Great and Small" but with people instead of animals or vingnettes from country doctors who took "A Walk in the Woods".Jourdan's first book is on hundreds of lists of best books of the year, best book club books, and funniest books. "Heart in the Right Place" was chosen as Family Circle magazine's first ever Book of the Month, won the Elle magazine Reader's Prize, named a Wall Street Journal Nonfiction Bestseller and ranked #1 on Amazon in Biography, Memoir, Science, and Medicine.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret.   No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe.