That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

    By demystifying the fantasies surrounding cancer, Sontag shows cancer for what it is--just a disease. Cancer, she argues, is not a curse, not a punishment, certainly not an embarrassment and, it is highly curable, if good treatment is followed.Almost a decade later, with the outbreak of a new, stigmatized disease replete with mystifications and punitive metaphors, Sontag wrote a sequel to Illness as Metaphor, extending the argument of the earlier book to the AIDS pandemic.These two essays now published together, Illness as Metaphor and AIDS and Its Metaphors, have been translated into many languages and continue to have an enormous influence on the thinking of medical professionals and, above all, on the lives of many thousands of patients and caregivers.

    

    Jack Geiger, M.D., New York Times Book Review

    This is true especially for women and girls; conservative estimates indicate that 99% of American women have tried hair removal, and at least 85% regularly remove hair from their faces, armpits, legs, and bikini lines. How and when does hair become a problem--what makes some growth "excessive"? Who or what separates the necessary from the superfluous? In Plucked, historian Rebecca Herzig addresses these questions about hair removal. She shows how, over time, dominant American beliefs about visible hair changed: where once elective hair removal was considered a "mutilation" practiced primarily by "savage" men, by the turn of the twentieth century, hair-free faces and limbs were expected for women. Visible hair growth--particularly on young, white women--came to be perceived as a sign of political extremism, sexual deviance, or mental illness. By the turn of the twenty-first century, more and more Americans were waxing, threading, shaving, or lasering themselves smooth. Herzig's extraordinary account also reveals some of the collateral damages of the intensifying pursuit of hair-free skin. Moving beyond the experiences of particular patients or clients, Herzig describes the surprising histories of race, science, industry, and medicine behind today's hair-removing tools. Plucked is an unsettling, gripping, and original tale of the lengths to which Americans will go to remove hair.

    After more than a decade of research, the celebrated scholar and activist Mab Segrest locates the deep historical roots of this startling fact, turning her sights on a long-forgotten cauldron of racial ideology: the state mental asylum system in which psychiatry was born and whose influences extend into our troubled present.In December 1841, the Georgia State Lunatic, Idiot, and Epileptic Asylum was founded. A hundred years later, it had become the largest insane asylum in the world with over ten thousand patients. Administrations of Lunacy tells the story of this iconic and infamous southern institution, a history that was all but erased from popular memory and within the psychiatric profession.Through riveting accounts of historical characters, Segrest reveals how modern psychiatric practice was forged in the traumas of slavery, the Civil War, Reconstruction, and Jim Crow. Deftly connecting this history to the modern era, Segrest then shows how a single asylum helped set the stage for the eugenics theories of the twentieth century and the persistent racial ideologies of our own times. She also traces the connections to today’s dissident psychiatric practices that offer sanity and create justice.A landmark of scholarship, Administrations of Lunacy restores a vital thread between past and present, revealing the tangled racial roots of psychiatry in America.

    An exposé of the psychiatric profession’s bible from a leading psychotherapist, The Book of Woe reveals the deeply flawed process by which mental disorders are invented and uninvented—and why increasing numbers of therapy patients are being declared mentally ill.

    Sex. Detox. Art. Recovery. Prostitution. Music. Street life. Poetry. Toxic love. And, those are just on the surface. The layers and complexities of Addictarium will shock and enthrall you... When wild-child, and south Florida escapee, Danielle Martino finds herself curled in a ball on the cold tile floors of her filthy rank bathroom in the tiny studio she rents with her fiancé and partner-in-crime, she knows it's time to quit abusing heroin. Severely impaired from shooting a bad batch of black tar heroin, and already partially blind from the infection that the muddy poison has caused, she is forced to hitch a greyhound bus to New York City, and to abandon her care-free, American-bohemian, drug infested life-style.Hailed by many as a beautiful, unique, honest, raw and poetic account of recovery, Addictarium takes readers on a compelling journey through the life and eyes of the narrator; a creative, nomadic, deep--but, incidentally broken--young woman, and underlines the contributing factors to what it's really like to suffer from addiction. With magnificent candor--and sometimes emotionally crippling descriptions--we witness Danielle's fight towards recovery from more than just heroin, as Addictarium brings the readers on a fascinating and harrowing, brutal tale of a young women's recovery from total and mass self-destruction. --Addictarium highlights in the starkest of lights, why it is so difficult for addicts to receive the recovery they seek, when they finally do decide to put the drug down.

    a family drama of love and loss.-- New York Times Rarely has a public figure addressed such difficult, intimate issues with such courage and bravery. In a moving, passionate memoir, former Senator George McGovern recalls the events leading up to his daughter Terry's death as a result of alcoholism. What McGovern learned from Terry is an unforgettable, poignant tale certain to engender controversy and compassion.

    It covers everything from its recreational use in the dance community, its use as an adjunct to psychotherapy as an aid in overcoming chemical dependency and alcoholism, to the types of mystical experiences induced by ketamine. This book includes information on the possible benfits and dangers of ketamine use along with an authoratative treatment plan for individuals who become addicted to the drug. It is wealth of information for both laypersons and medical professionals alike.

    Rick Strassman conducted US DEA-approved clinical research at the University of New Mexico in which he injected 60 volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical that is also manufactured by the human brain, consistently produced near-death and mystical experiences. Many volunteers reported convincing encounters with intelligent nonhuman presences, especially "aliens." Nearly all felt that the sessions were among the most profound experiences of their lives.Strassman's research connects DMT with the pineal gland, considered by Hindus to be the site of the seventh chakra and by René Descartes to be the seat of the soul. DMT: The Spirit Molecule makes the case that DMT, naturally released by the pineal gland, facilitates the soul's movement in and out of the body and is an integral part of the birth and death experiences, as well as the highest states of meditation and even sexual transcendence. Strassman also believes that alien abduction experiences are brought on by accidental releases of DMT. If used wisely, DMT could trigger a period of remarkable progress in the scientific exploration of the most mystical regions of the human mind and soul.

    Edward Marriott’s dramatic, gripping new book gives you yet another thing to worry about.” —New York Plague. The very word carries an unholy resonance. No other disease can claim its apocalyptic power: it can lie dormant for centuries, only to resurface with nation-killing force. Here, with the high drama of an adventure tale, Edward Marriott unravels the story of this lethal disease: the historic battle to identify its source, the devastating effects of pandemics, and the prospects for new outbreaks. Marriott begins the trail in Hong Kong in the summer of 1894, when a plague diagnosis brought to the island two top scientists—Alexandre Yersin, a maverick Frenchman, and his Japanese rival, Shibasaburo Kitasato. Marriott interweaves the narrative of their fierce competition with vivid scenes of the scourge’s persistence: California in 1900; Surat, India, in 1994; and New York City sometime in the future.A masterly account of medical and human history, Plague is at once an instructive warning and a chilling read.

    Richard Louis Miller discusses what is happening today in psychedelic medicine--and what will happen in the future--with top researchers and thinkers in this field, including Rick Doblin, Stanislav Grof, James Fadiman, Julie Holland, Dennis McKenna, David Nichols, Charles Grob, Phil Wolfson, Michael and Annie Mithoefer, Roland Griffiths, Katherine MacLean, and Robert Whitaker. Dr. Miller and his contributors cover the tumultuous history of early psychedelic research brought to a halt 50 years ago by the U.S. government as well as offering non-technical summaries of the most recent studies with MDMA, psilocybin, LSD, and ayahuasca. They explore the biochemistry of consciousness and the use of psychedelics for self-discovery and healing. They discuss the use of psilocybin for releasing fear in the terminally ill and the potential for MDMA-assisted psychotherapy in the treatment of PTSD. They examine Dr. Charles Grob’s research on the indigenous use and therapeutic properties of ayahuasca and Dr. Gabor Mate’s attempt to transport this plant medicine to a clinical setting with the help of Canada’s Department of National Health. Dr. Miller and his contributors explore the ongoing efforts to restore psychedelic therapies to the health field, the growing threat of overmedication by the pharmaceutical industry, and the links between psychiatric drugs and mental illness. They also discuss the newly shifting political climate and the push for new research, offering hope for an end to the War on Drugs and a potential renaissance of research into psychedelic medicines around the world.

    Even modern neuroscience has tended, until recently, to concentrate on the cognitive aspects of brain function, disregarding emotions. This attitude began to change with the publication of Descartes’ Error in 1995. Antonio Damasio—"one of the world’s leading neurologists" (The New York Times)—challenged traditional ideas about the connection between emotions and rationality. In this wondrously engaging book, Damasio takes the reader on a journey of scientific discovery through a series of case studies, demonstrating what many of us have long suspected: emotions are not a luxury, they are essential to rational thinking and to normal social behavior.

    March 1986. The world is made of junk: junk bonds, junk food, junk powder. At least, that's how it seems to a woman in a downtown walkup, where every day for five years she's been opening her door to people engaged in the culture of the moment. Some of them are getting famous, some are changing their sex, while others are dying. But all of them are buying her heroin, and one of them is a rat: one morning she opens the door to a drug-enforcement agent - Dick.