These beautifully rendered tales illuminate the fundamental pathways of life from birth to death.A woman finds herself daydreaming as she returns home from a business trip; a young man loses his wallet. We learn, too, from more extreme examples: the patient who points an unloaded gun at a police officer, the compulsive liar who convinces his wife he's dying of cancer. The stories invite compassionate understanding, suggesting answers to the questions that compel and disturb us most about love and loss, parents and children, work and change. The resulting journey will spark new ideas about who we are and why we do what we do.

      In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    Diagnosed with retinitis pigmentosa, Burke has been legally blind since age five, and became completely sightless as a teenager. Here, she tackles the preconceived notions we have around blindness, her struggles with bullying and anxiety, inclusivity, how she built her successful influencer business (with over 1.8 million followers), and what it’s really like to travel the globe with her service dog, Gallop, now that everyone has an emotional support animal. (Hint: Really hard!) This is a beautifully voiced, honest, and rousing journey of a young woman who has made it her mission to make us see her and the disability community in a totally new way.

    When we are stuck, talk therapy often fails to produce the needed connections between the old emotional memory and a more grounded view of reality, and medications can have dire side effects and limited effectiveness.   In Getting Past Your Past, Francine Shapiro, who created EMDR (the “eye movement” therapy), opens the door to a scientifically proven mode of treatment used by thousands of clinicians worldwide. The book offers practical procedures that demystify the process and empower readers looking to break free from emotional roadblocks. Shapiro explains the brain science in layman’s terms and provides simple exercises that readers can do at home to achieve real change.   “I always came out of my EMDR therapist’s office reeling (in a good way); and the things I learnedhave stayed with me and enriched my conscious mind. It’s a powerful process. I recommend it.”—from The Noonday Demon by Andrew Solomon

    New scientific research has transformed old ideas about personality based on the theories of Freud, Jung, and the humanistic psychologies of the nineteen sixties, which gave rise to the simplistic categorizations of the Meyer-Briggs Inventory and the "enneagream." But the general public still knows little about the new science and what it reveals about who we are.In Me, Myself, and Us, Brian Little, Ph.D., one of the psychologists who helped re-shape the field, provides the first in-depth exploration of the new personality science and its provocative findings for general readers. The book explores questions that are rooted in the origins of human consciousness but are as commonplace as yesterday's breakfast conversation. Are our first impressions of other people's personalities usually fallacious? Are creative individuals essentially maladjusted? Are our personality traits, as William James put it, "set like plaster" by the age of thirty? Is a belief that we are in control of our lives an unmitigated good? Do our singular personalities comprise one unified self or a confederacy of selves, and if the latter, which of our mini-mes do we offer up in marriage or mergers? Are some individuals genetically hard-wired for happiness? Which is the more viable path toward human flourishing, the pursuit of happiness or the happiness of pursuit?Little provides a resource for answering such questions, and a framework through which readers can explore the personal implications of the new science of personality. Questionnaires and interactive assessments throughout the book facilitate self-exploration, and clarify some of the stranger aspects of our own conduct and that of others. Brian Little helps us see ourselves, and other selves, as somewhat less perplexing and definitely more intriguing.This is not a self-help book, but students at Harvard who took the lecture course on which it is based claim that it changed their lives.

    Through decades of music by one of the best-selling musicians of all time, who created classics like "Fire and Rain" and "Carolina in My Mind," James Taylor has doled out his history in the poetry of his work. Taylor says his early life is, "the source of many of my songs," and Break Shot is a tour of his first 21 years in rich, new detail. Praised by Forbes magazine as going "beyond the spoken word," Break Shot combines storytelling, music and performance to create a one-of-a-kind listening experience. Longtime fans will savor a crop of musical gems, including an unreleased recording of the beloved hymn "Jerusalem," selections from his newest release American Standard, as well as new original scoring by Taylor specially recorded for Break Shot and more from the Grammy Award-winning artist.Recorded in his home studio, TheBarn in western Massachusetts, Taylor tells the deeply personal story of his youth, which is entwined with the story of his family. What started as an idyllic tight unit soon became a family sent to different emotional corners—like a break shot in the game of pool, he says, when you slam the cue ball into the fifteen other balls and they all go flying off. By the time Taylor released his breakout second album in 1970, Sweet Baby James, he had seen the disintegration of his parents’ marriage and his family crumble in the aftermath. He had committed himself twice to a psychiatric hospital, battled depression, a heroin addiction, suffered a relapse, and traveled far away from the wood smoke and moonshine of the North Carolina landscapes in which he came of age. Despite it all, he was also on the cusp of superstardom and on his way to bringing light and joy to millions. He was 21.Journey with James Taylor to a time before he became a Rock & Roll Hall of Fame and Songwriters Hall of Fame inductee, a recipient of the Kennedy Center Honors and both the Presidential Medal of Freedom and the National Medal of Arts—and a beloved voice to millions.

    In fact, a plethora of parasites affect our behavior in ways we have barely begun to understand.  In this mind-bending book, McAuliffe reveals the eons-old war between parasites and other creatures that is playing out in our very own bodies. And more surprising still, she uncovers the decisive role that parasites may have played in the rise and demise of entire civilizations. Our obsession with cleanliness and our experience of disgust are both evolutionary tools for avoiding infection, but they evolved differently for different populations. Political, social, and religious differences among societies may be caused, in part, by the different parasites that prey on us. In the tradition of Jared Diamond’s Guns, Germs, and Steel and Neil Shubin’s Your Inner Fish, This Is Your Brain on Parasites is both a journey into cutting-edge science and a revelatory examination of what it means to be human.

    Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself.Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system.In Pain in America is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

    But that's much more easily said than done. What does being happy actually mean? And how do you even know when you feel it?Across the millennia, philosophers have thought long and hard about happiness, and come up with all sorts of different definitions and ideas for how we might live a happier life. Here, Derren explores the history of happiness from classical times until today, when the self-help industry has attempted to claim happiness as its own. His aim is to reclaim happiness for us all, and enable us to appreciate the really good things in life for what they are.Fascinating, entertaining and revelatory, this is a book for anyone who has ever wondered if there must be more to life...

    Cacioppo’s groundbreaking research topples one of the pillars of modern medicine and psychology: the focus on the individual as the unit of inquiry. By employing brain scans, monitoring blood pressure, and analyzing immune function, he demonstrates the overpowering influence of social context—a factor so strong that it can alter DNA replication. He defines an unrecognized syndrome—chronic loneliness—brings it out of the shadow of its cousin depression, and shows how this subjective sense of social isolation uniquely disrupts our perceptions, behavior, and physiology, becoming a trap that not only reinforces isolation but can also lead to early death. He gives the lie to the Hobbesian view of human nature as a “war of all against all,” and he shows how social cooperation is, in fact, humanity’s defining characteristic. Most important, he shows how we can break the trap of isolation for our benefit both as individuals and as a society.

    F. Heller reveal how an understanding of attachment theory-the most advanced relationship science in existence today-can help us find and sustain love. Attachment theory forms the basis for many bestselling books on the parent/child relationship, but there has yet to be an accessible guide to what this fascinating science has to tell us about adult romantic relationships-until now.Attachment theory owes its inception to British psychologist and psychoanalyst John Bowlby, who in the 1950s examined the tremendous impact that our early relationships with our parents or caregivers has on the people we become. Also central to attachment theory is the discovery that our need to be in a close relationship with one or more individuals is embedded in our genes.In Attached, Levine and Heller trace how these evolutionary influences continue to shape who we are in our relationships today. According to attachment theory, every person behaves in relationships in one of three distinct ways:*ANXIOUS people are often preoccupied with their relationships and tend to worry about their partner's ability to love them back.*AVOIDANT people equate intimacy with a loss of independence and constantly try to minimize closeness.*SECURE people feel comfortable with intimacy and are usually warm and loving.Attached guides readers in determining what attachment style they and their mate (or potential mates) follow. It also offers readers a wealth of advice on how to navigate their relationships more wisely given their attachment style and that of their partner. An insightful look at the science behind love, Attached offers readers a road map for building stronger, more fulfilling connections.

    But what we eat affects more than our bodies; it also affects our brains. And recent studies have shown that diet can have a profound impact on mental health conditions ranging from ADHD to depression, anxiety, sleep disorders, OCD, dementia and beyond.A triple threat in the food space, Dr. Uma Naidoo is a board-certified psychiatrist, nutrition specialist, and professionally trained chef. In This Is Your Brain on Food, she draws on cutting-edge research to explain the many ways in which food contributes to our mental health, and shows how a sound diet can help treat and prevent a wide range of psychological and cognitive health issues.Packed with fascinating science, actionable nutritional recommendations, and delicious, brain-healthy recipes, This Is Your Brain on Food is the go-to guide to optimizing your mental health with food.

    Elite athletes have known this for decades and now science is learning why it s true. In his fascinating new book "How Bad Do You Want It?," coach Matt Fitzgerald examines more than a dozen pivotal races to discover the surprising ways elite athletes strengthen their mental toughness.Fitzgerald puts you into the pulse-pounding action of more than a dozen epic races from running, cycling, triathlon, XTERRA, and rowing with thrilling race reports and revealing post-race interviews with the elites. Their own words reinforce what the research has found: strong mental fitness lets us approach our true physical limits, giving us an edge over physically stronger competitors. Each chapter explores the how and why of an elite athlete s transformative moment, revealing powerful new psychobiological principles you can practice to flex your own mental fitness.The new psychobiological model of endurance performance shows that the most important question in endurance sports is: how bad do you want it? Fitzgerald s fascinating book will forever change how you answer this question and show you how to master the psychology of mind over muscle. These lessons will help you push back your limits and uncover your full potential."How Bad Do You Want It?" reveals new psychobiological findings including: Mental toughness determines how close you can get to your physical limit. Bracing yourself for a tough race or workout can boost performance by 15% or more. Champions have learned how to give more of what they have. The only way to improve performance is by altering how you perceive effort. Choking under pressure is a form of self-consciousness. Your attitude in daily life is the same one you bring to sports. There's no such thing as going as fast as you can only going faster than before. The fastest racecourse is the one with the loudest spectators. Faith in your training is as important as the training itself.Athletes featured in "How Bad Do You Want It?" Sammy Wanjiru, Jenny Simpson, Greg LeMond, Siri Lindley, Willie Stewart, Cadel Evans, Nathan Cohen and Joe Sullivan, Paula Newby-Fraser, Ryan Vail, Thomas Voeckler, Ned Overend, Steve Prefontaine, and last of all John The Penguin Bingham"

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    Through vividly told public and private anecdotes, the Audible Original weaves a raw and revealing journey of motherhood, loss, mental illness, and feminism. Co-written with Alix Sobler and directed by Kimberly Senior, Certain Woman of an Age is "fearless and vulnerable" (Chicago Tribune).International mental health advocate Margaret Trudeau brought her intimate solo performance, Certain Woman of an Age, to the Minetta Lane Theatre, where it was recorded live for Audible Theater.