But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    And because you’re already more attuned to your physical and emotional needs, and more inclined to commit to a healthier lifestyle, you're poised to live brilliantly for the thirty-plus years after menopause. All you need now is the program outlined in Younger Next Year for Women—which, for starters, will help you avoid literally 70 percent of the decay and eliminate 50 percent of the injuries and illnesses associated with getting older. How? Drawn from disciplines as varied as evolutionary biology, cell physiology, experimental psychology and anthropology, the science behind Younger Next Year is clear. Our bodies are programmed to do one of two things: either grow or decay. Sitting in front of a screen all day tells the body to decay. Taking a walk or doing yoga tells the body to grow. Loneliness and stress trigger decay; love and laughter trigger growth. Just as clear as the science is the goal: Become the active gatekeeper of your own body and gain the power to control those signals of growth and decay. Seven simple rules show the way, from #1 Exercise six days a week for the rest of your life, to #6 Care, to #7 Connect and commit. They’re called Harry’s Rules, named for the doctor and coauthor—Henry S. Lodge, M.D.—who formulated them, and who explains the precise science behind each one. But since it’s one thing to know something’s good for you and quite another to put it into practice, Dr. Lodge, the scientist, is joined by Chris Crowley—coauthor, exhorter and living example—whose brusque charm and infectious enthusiasm will actually have you living by the rules. So, congratulations. You’re now about to get younger.

    Dr. Manheimer describes the plights of twelve very different patients--from dignitaries at the nearby UN, to supermax prisoners at Riker's Island, to illegal immigrants, and Wall Street tycoons.Manheimer was not only the medical director of the country's oldest public hospital for over 13 years, but he was also a patient. As the book unfolds, the narrator is diagnosed with cancer, and he is forced to wrestle with the end of his own life even as he struggles to save the lives of others.