In First You Build a Cloud, K. C. Cole provides cogent explanations through animated prose, metaphors, and anecdotes, allowing us to comprehend the nuances of physics-gravity and light, color and shape, quarks and quasars, particles and stars, force and strength. We also come to see how the physical world is so deeply intertwined with the ways in which we think about culture, poetry, and philosophy. Cole, one of our preeminent science writers, serves as a guide into the world of such legendary scientific minds as Richard Feynman, Victor Weisskopf, brothers Frank Oppenheimer and J. Robert Oppenheimer, Philip Morrison, Vera Kistiakowsky, and Stephen Jay Gould.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    The Kingfisher Science Encyclopedia is the one reference that includes all of the information students need to know in today's fast-paced world. Clearly written and illustrated articles provide in-depth insight and concise authoritative information. An impressive reference section at the end of the book contains minibiographies of famous scientists, plus an illustrated time line of key inventions and discoveries. Arranged thematically into ten chapters, with reference summaries at the end of each chapter and a full index, the encyclopedia does more than merely provide facts about science and technology—it helps the reader think for him or herself, develop an enquiring mind, pose challenging questions, and explore new topics.

    In The Life of the Cosmos, Smolin cuts the Gordian knot of cosmology with a simple, powerful idea: "The underlying structure of our world, " he writes, "is to be found in the logic of evolution." Today's physicists have overturned Newton's view of the universe, yet they continue to cling to an understanding of reality not unlike Newton's own - as a clock, an intricate mechanism, governed by laws which are mathematical and eternally true. Smolin argues that the laws of nature we observe may be in part the result of a process of natural selection which took place before the big bang. Smolin's ideas are based on recent developments in cosmology, quantum theory, relativity and string theory, yet they offer, at the same time, an unprecedented view of how these developments may fit together to form a new theory of cosmology. From this perspective, the lines between the simple and the complex, the fundamental and the emergent, and even between the biological and the physical are redrawn. The result is a framework that illuminates many intractable problems, from the paradoxes of quantum theory and the nature of space and time to the problem of constructing a final theory of physics. As he argues for this new view, Smolin introduces the reader to recent developments in a wide range of fields, from string theory and quantum gravity to evolutionary theory the structure of galaxies. He examines the philosophical roots of controversies in the foundations of physics, and shows how they may be transformed as science moves towardunderstanding the universe as an interrelated, self-constructed entity, within which life and complexity have a natural place, and in which "the occurrence of novelty, indeed the perpetual birth of novelty, can be understood."

    This book was originally written by third-year medical students searching for the perfect review book--not finding it on the market, they wrote it themselves! Now in its third edition, Step-Up to Medicine boils down the full scope of tested pathology in a single ingenious tool. Each element is tailored for immediate content absorption, and an all-new, full-color interior differentiate elements for even faster, more efficient review. And, Step-Up to Medicine , third edition provides two types of self-assessment--the kinds of questions you will ask yourself as a clinician plus USMLE-style practice questions. This review book gives you just the Step-Up to the medicine clerkship, accompanying shelf exams, and USMLE Step 2 that you need! NEW Features for this blockbuster edition: Full-color, updated interior design brings the content to you in a rousing, memorable style. Full-color, updated art program illustrates concepts when a picture says it best--plenty of clinical images also supplement topics. New content on evidence-based medicine keeps you current and informed to guide your clinical decision making. Expanded content on drug dosing is added where relevant.CLASSIC Features students swear by: Complete coverage of high-yield medical topics ensures you are test ready Clinical Pearls boxes help you "file away" clinical medicine connections for handy retrieval at test time Quick Hits glimmering in the margins highlight highly testable material--just see how the sparks fly at test timeBONUS Material and study resources: eBook with the fully searchable text is available via thePoint . NEW 300 USMLE-style questions provide another means of self-assessment and practice for those exams NEW Audio clips of breath and heart sounds also available on thePoint

    Guns, Germs, and Steel: The Fates of Human Societies is a 1997 book by Jared Diamond, professor of geography and physiology at the University of California, Los Angeles (UCLA). In 1998 it won a Pulitzer Prize and the Aventis Prize for Best Science Book. A documentary based on the book and produced by the National Geographic Society was broadcast on PBS in July 2005.

    Science has seen its fair share of punch-ups over the years, but one debate, in the field of biology, has become notorious for its intensity. Over the last twenty years, Richard Dawkins and Stephen Jay Gould have engaged in a savage battle over evolution, which continues to rage even after Gould's death in 2002. Kim Sterelny moves beyond caricature to expose the real differences between the conceptions of evolution of these two leading scientists. He shows that the conflict extends beyond evolution to their very beliefs in science itself; and, in Gould?s case, to domains in which science plays no role at all.

    Murray's best-selling book "the most colorful and fun text to read in medical microbiology." Now it's back in an updated New Edition-and it's as succinct, user-friendly, and authoritative as ever. Readers will continue to enjoy its lucid discussions of how microbes cause disease in humans. Expert coverage of basic principles, the immune response, laboratory diagnosis, bacteriology, virology, mycology, and parasitology ensures they understand all the facts vital to the practice of medicine today. More than 550 brilliant full-color images make complex information easy to understand and illustrate the appearance of disease.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.

    He was trying to find an equation that explained all physical reality - a theory of everything. He failed, but others have taken up the challenge in a remarkable quest that is shedding light on unsuspected secrets of the cosmos.Experimental physicist and award-winning educator Dr. Don Lincoln of the Fermi National Accelerator Laboratory takes you on this exciting journey in The Theory of Everything: The Quest to Explain All Reality. Suitable for the intellectually curious at all levels and assuming no background beyond basic high-school math, these 24 half-hour lectures cover recent developments at the forefront of particle physics and cosmology, while delving into the history of the centuries-long search for this holy grail of science.You trace the dream of a theory of everything through Newton, Maxwell, Einstein, Bohr, Schrödinger, Feynman, Gell-Mann, Weinberg, and other great physicists, charting their progress toward an all-embracing, unifying theory. Their resulting equations are the masterpieces of physics, which Dr. Lincoln explains in fascinating and accessible detail. Studying them is like touring a museum of great works of art - works that are progressing toward an ultimate, as-yet-unfinished masterpiece.Listening Length: 12 hours and 21 minutes

    The book begins with relevant scientific fundamentals and progresses through an exploration of the solar system, stars, galaxies, and cosmology. The Astronomy textbook builds student understanding through the use of relevant analogies, clear and non-technical explanations, and rich illustrations. Mathematics is included in a flexible manner to meet the needs of individual instructors.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Lewis Dartnell considers some of the fascinating questions facing researchers today. Could life exist anywhere else in the universe? What might aliens really look like? Dartnell explains why Earth is uniquely suited for life and reveals our profound connection to the cosmos.

    Many studies have supported this, proving that life expectancy is 75 to 90 percent due to habits and only 10 to 25 percent due to genetics. This means that someone who is genetically destined to die at age 100 may not live past age 60 because of poor habits and lifestyle choices that cause accelerated aging and premature death. Conversely, a person can live to 100 and be functionally healthy. In this highly anticipated follow-up, Diana Schwarzbein, M.D., goes beyond the diet she introduced in her first book—which literally helped thousands of people lose weight—and offers a personalized anti-aging program for readers to heal their metabolisms and stop advanced aging in its tracks. Weaving in groundbreaking research and provocative case studies—including her own regeneration and that of her clients—she leads readers through a series of eye-opening questionnaires, which identify where they are on their path to either accelerated or healthy aging. Based on readers’ answers, she leads them to the “how-to” sections, which explain, in easy-to-follow and personalized detail, the steps they need to take to restore healthy functioning. For each unique situation, she covers five areas: Nutrition , Hormone Replacement Therapy (if needed), Tapering Off Toxic Chemicals or Avoiding Them Completely , Cross-Training Exercises and Stress Management. The Schwarzbein Principle II is sure to follow the success of the first book and will help people live a more healthful lifestyle by embracing a regeneration process to prevent and reverse accelerated aging.

    The complexity of nature's shapes differs in kind, not merely degree, from that of the shapes of ordinary geometry, the geometry of fractal shapes.Now that the field has expanded greatly with many active researchers, Mandelbrot presents the definitive overview of the origins of his ideas and their new applications. The Fractal Geometry of Nature is based on his highly acclaimed earlier work, but has much broader and deeper coverage and more extensive illustrations.

    Accompanying this unique perspective on our ever-evolving view of the universe are some of the most visually dramatic illustrations you'll ever see. Short, lucid articles focus on everything from the speculations of the ancient Greeks to today's Nobel Prize winners, from Ptolemy's theory of an Earth-centered universe to the first steps on the moon, and from the dawning of the concept of zero to the cloning of Dolly the sheep. Biology, physics, astronomy, medicine, and mathematics: the breakthroughs in every field are all here and celebrated, in the first truly accessible, fully illustrated story of science.