The thoroughly revised and updated 18th Edition is packed with essential information on diagnosing and treating medical disorders to help medical professionals deliver the best care to their patients. This handy, compact guide was written by a team of clinicians for everyday use. Designed for maximum clinical utility, the new Merck Manual of Diagnosis and Therapy makes it easy to find the right information, right when it is needed. It is a must-have for medical students, residents, practicing physicians, nurses, and allied health professionals.Featuring: All new "approach" chapters All-new abstract summaries 341 total chapters 34 completely new chapters 69 new illustrations New cross-referencing Two-color presentation Brand new content on: critical care medicine, metabolic syndrome, acute lung injury, biological warfare and terrorism, SARS, smallpox, and more

    What she did not count on was how much death would be a part of her work. Almost immediately, Chen found herself wrestling with medicine’s most profound paradox, that a profession premised on caring for the ill also systematically depersonalizes dying. Final Exam follows Chen over the course of her education, training, and practice as she grapples at strikingly close range with the problem of mortality, and struggles to reconcile the lessons of her training with her innate knowledge of shared humanity, and to separate her ideas about healing from her fierce desire to cure.From her first dissection of a cadaver in gross anatomy to the moment she first puts a scalpel to a living person; from the first time she witnesses someone flatlining in the emergency room to the first time she pronounces a patient dead, Chen is struck by her own mortal fears: there was a dying friend she could not call; a young patient’s tortured death she could not forget; even the sense of shared kinship with a corpse she could not cast aside when asked to saw its pelvis in two. Gradually, as she confronts the ways in which her fears have incapacitated her, she begins to reject what she has been taught about suppressing her feelings for her patients, and she begins to carve out a new role for herself as a physician and as human being. Chen’s transfixing and beautiful rumination on how doctors negotiate the ineluctable fact of death becomes, in the end, a brilliant questioning of how we should live.Moving and provocative, motored equally by clinical expertise and extraordinary personal grace, this is a piercing and compassionate journey into the heart of a world that is hidden and yet touches all of our lives. A superb addition to the best medical literature of our time.

    Chronic Fatigue Syndrome (CFIDS) and fibromyalgia are illnesses characterized by severe long-term fatigue, achiness, "brain fog," and recurrent infections, among other symptoms. The conditions are frequently misdiagnosed and patients often receive confusing and misleading information from health practitioners.Dr. Teitelbaum, one of the country's leading experts on CFIDS and fibromyalgia, has experienced and overcome these illnesses himself. In this revised edition of his landmark book, he examines the possible causes of the disorders and provides instructions for patients on how to eliminate them, using both natural and pharmacological methods. He offers compelling evidence that these disorders can be treated effectively, and provides the latest scientific research and cutting-edge discoveries about these diseases as well as sound, compassionate advice on dealing with them. Notes. Index.

    All the advances of modern life--the medical breakthroughs, the public health institutions, the rising standards of living--have given us each about twenty thousand extra days on average. There are few measures of human progress more astonishing than our increased longevity.This book is Steven Johnson's attempt to understand where that progress came from. How many of those extra twenty thousand days came from vaccines, or the decrease in famines, or seatbelts? What are the forces that now keep us alive longer? Behind each breakthrough lies an inspiring story of cooperative innovation, of brilliant thinkers bolstered by strong systems of public support and collaborative networks.But it is not enough simply to remind ourselves that progress is possible. How do we avoid decreases in life expectancy as our public health systems face unprecedented challenges? What current technologies or interventions that could reduce the impact of future crises are we somehow ignoring?

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.

    It all boils down to what Dr. Cate calls the Fatburn Factor, or the body’s natural-born ability to burn body fat as fuel. After years of research and observing the patients in her practice, Dr. Cate discovered that there are certain enzymes required for the body to seek out and utilize body fat for energy. Without these enzymes, people lose the ability to burn fat, making weight gain almost unavoidable. Worse, the loss of your fat-burning enzymes causes your cells to depend on sugar for energy. This leads to elevated blood sugar, putting you at risk for diabetes, and disrupts nearly every hormone in your body. Now, in The Fatburn Fix, Dr. Cate lays out a step-by-step plan to help reboot your fat burn potential in as little as two weeks, opening the door to a lifetime of looking and feeling better than you ever thought possible. This comprehensive guide includes complete meal plans, recipes, and exercise tips that not only repair damage to your metabolism, but also address the number one cause of weight retention and regain. How does it work? The program magnifies your fat burn capacity by training your cells to burn body fat on demand. By making a few changes what you eat (and when)—such as reducing carbohydrates, switching out toxic fats for healthy ones, and adding high-quality proteins—your body will produce the enzymes that allow it to seek out and utilize body fat for energy. Regaining your fat burn potential allows you to free yourself from dependence on sugar – and avoid a constellation of chronic diseases as a result.Improving your Fatburn Factor is the key to a new, healthier relationship between you and your body, paving the way for a faster, smoother, and more permanent journey to optimum health, weight, and happiness.

    Unable to stand, barely able to think, he waited for hours in an emergency room before being correctly diagnosed and rushed into surgery. Over the next few days, as he clung to life and the first light of a new year came through his window, he found himself reflecting on the fragility of health, not recognized in America as a human right but without which all rights and freedoms have no meaning.And that was before the pandemic. We have since watched American hospitals, long understaffed and undersupplied, buckling under waves of coronavirus patients. The federal government made matters worse through willful ignorance, misinformation, and profiteering. Our system of commercial medicine failed the ultimate test, and thousands of Americans died.In this eye-opening cri de coeur, Snyder traces the societal forces that led us here and outlines the lessons we must learn to survive. In examining some of the darkest moments of recent history and of his own life, Snyder finds glimmers of hope and principles that could lead us out of our current malaise. Only by enshrining healthcare as a human right, elevating the authority of doctors and medical knowledge, and planning for our children's future can we create an America where everyone is truly free.

    In this groundbreaking book, Goodavage brings us behind the scenes of cutting-edge science at top research centers, and into the lives of people whose well-being depends on their devoted, highly skilled personal MDs (medical dogs). With her signature wit and passion, Goodavage explores how doctor dogs are becoming our happy allies in the fight against dozens of physical and mental conditions.We meet dogs who detect cancer and Parkinson's disease, and dogs who alert people to seizures and diabetic lows or highs and other life-threatening physical ailments. Goodavage reveals the revolutionary ways dogs are helping those with autism, anxiety, depression, schizophrenia, and post-traumatic stress disorder. And she introduces us to intrepid canines who are protecting us from antibiotic-resistant bugs, and to dogs who may one day help keep us safe from epidemic catastrophe. Their paycheck for their lifesaving work? Heartfelt praise and a tasty treat or favorite toy.The emotional element in Doctor Dogs delivers as powerfully as the science. You don't have to be a dog lover to care deeply about what these dogs are doing and what we are learning from them--although if you're not a dog lover, you probably will be by the end of the book.

    He made life worth living. But most importantly, he empowered me to find and reclaim myself again' Lady GagaDo the work to heal yourself and find a path through trauma.Trauma is everywhere and so many of us are silently affected by it. Stressful, challenging and frightening events can happen to anyone, at any age, leaving us feeling overwhelmed, anxious and exhausted. Left unchecked, difficult experiences can have a lasting psychological effect on our wellbeing.In Trauma: The Invisible Epidemic, leading psychiatrist Dr Paul Conti sets out a unique set of tools anyone can access to help recognise the signs of trauma, heal from past hurt and find the road to recovery.Drawing on the most recent scientific research, Dr Conti breaks down the topic into clear sections, looking at why trauma happens, how it manifests in the body and what we can do to move past it. In the book, you'll discover the three different types of trauma you might face, as well as practical exercises and solutions for getting to the root of the problem.This is an important, life-affirming book, one that invites you to empower yourself against trauma, own your life experiences and learn to thrive, not just survive, in the wake of life's difficulties.

    In fact, your body is actually endowed with many self-defense measures to hold on to fat. For example, fat can use stem cells to regenerate; increase our appetite if it feels threatened; and use bacteria, genetics, and viruses to expand itself. The secret to losing twenty pounds? You have to work with your fat, not against it. Tara explains how your fat influences your appetite and willpower, how it defends itself when attacked, and why it grows back so quickly. The Secret Life of Fat brings cutting-edge research together with historical perspectives to reveal fat’s true identity: an endocrine organ that, in the right amount, is critical to our health. Fat triggers puberty, enables our reproductive and immune systems, and even affects brain size.Although we spend $60 billion annually fighting fat, our efforts are often misinformed and misdirected. Tara expertly illustrates the complex role that genetics, hormones, diet, exercise, and history play in our weight, and The Secret Life of Fat sets you on the path to beat the bulge once and for all.

    That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we've made old age into a disease, a condition to be dreaded, denigrated, neglected, and denied. Reminiscent of Oliver Sacks, noted Harvard-trained geriatrician Louise Aronson uses stories from her quarter century of caring for patients, and draws from history, science, literature, popular culture, and her own life to weave a vision of old age that's neither nightmare nor utopian fantasy--a vision full of joy, wonder, frustration, outrage, and hope about aging, medicine, and humanity itself. Elderhood is for anyone who is, in the author's own words, "an aging, i.e., still-breathing human being."

    Our bodies are hardwired for sweets, so food giants have developed fifty-six types of sugar to add to their products, creating in us the expectation that everything should be cloying; we've evolved to prefer fast, convenient meals, hence our modern-day preference for ready-to-eat foods. Moss goes on to show how the processed food industry--including major companies like Nestlé, Mars, and Kellogg's--has tried not only to evade this troubling discovery about the addictiveness of food but to actually exploit it. For instance, in response to recent dieting trends, food manufacturers have simply turned junk food into junk diets, filling grocery stores with "diet" foods that are hardly distinguishable from the products that got us into trouble in the first place. As obesity rates continue to climb, manufacturers are now claiming to add ingredients that can effortlessly cure our compulsive eating habits. An account of the legal battles, insidious marketing campaigns, and cutting-edge food science that have brought us to our current public health crisis, Moss lays out all that the food industry is doing to exploit and deepen our addictions, and shows us why what we eat has never mattered more.From the #1 New York Times bestselling author of Salt Sugar Fat comes a powerful exposé of how the processed food industry exploits our evolutionary instincts, the emotions we associate with food, and legal loopholes in their pursuit of profit over public health.

    While it's true that we live in an age when we're as obsessed with our bodies as we are with celebrity hairstyles, the reality is that most of us know very little about what chugs, churns, and thumps throughout this miraculous, scientific, and artistic system of anatomy. Yes, you've owned your skin-covered shell for decades, but you probably know more about your cell-phone plan than you do about your own body. When it comes to your longevity and quality of life, understanding your internal systems gives you the power, authority, and ability to live a healthier, younger, and better life. "You: The Owner's Manual" challenges your preconceived notions about how the human body works and ages, then takes you on a tour through all of the highways, back roads, and landmarks inside of you. After taking a quiz that tests your body of knowledge, you'll learn about all of your blood-pumping, food-digesting, and keys-remembering systems and organs.Just as important, you'll get the facts and advice you need to keep your body running long and strong. You'll find out how diseases start and how they affect your body -- as well as advice on how to prevent and beat conditions that threaten your quality of life. Complete with exercise tips, nutritional guidelines, simple lifestyle changes, and alternative approaches, "You: The Owner's Manual" gives you an easy, comprehensive, and life-changing how-to plan for fending off the gremlins of aging. To top it off, you'll also get the great-tasting and calorie-saving Owner's Manual Diet -- a thirty-recipe eating plan that's designedwith only one goal in mind: to help you live a younger life.Welcome to your body. Why don't you come on in and take a look around?

    Will Bulsiewicz, or "Dr. B," illuminates in this groundbreaking book, the explosion of studies on the microbiome makes it abundantly clear that elimination diets are in fact hazardous to our health. What studies clearly now show--and what Dr. B preaches with his patients--is that gut health is the key to boosting our metabolism, balancing our hormones, and taming the inflammation that causes a host of diseases. And the scientifically proven way to fuel our guts is with dietary fiber from an abundant variety of colorful plants.Forget about the fiber your grandmother used to take--the cutting-edge science on fiber is incredibly exciting. As Dr. B explains, fiber energizes our gut microbes to create powerhouse postbiotics called short-chain fatty acids (SCFAs) that are essential to our health. SCFAs are scientifically proven to promote weight loss, repair leaky gut, strengthen the microbiome, optimize the immune system, reduce food sensitivities, lower cholesterol, reverse type 2 diabetes, improve brain function, and even prevent cancer. Restrictive fad diets starve the gut of the critical fiber we need, weaken the microbes, and make our system vulnerable.As a former junk-food junkie, Dr. B knows firsthand the power of fiber to dramatically transform our health. The good news is that our guts can be trained. Fiber-rich, real foods--with fruits, vegetables, whole grains, seeds, nuts, and legumes--start working quickly and maintain your long-term health, promote weight loss, and allow you to thrive and feel great from the inside out.With a 28-day jumpstart program with menus and more than 65 recipes, along with essential advice on food sensitivities, Fiber Fueled offers the blueprint to start turbocharging your gut for lifelong health today.

    Now, in Head Strong, Asprey shows readers how to biohack their way to a sharper, smarter, faster, more resilient brain.Imagine feeling like your mind is operating at its clearest and sharpest, and being able—possibly for the first time in your life—to do more in less time? What it suddenly became easier to do the very hardest things you do? Or if you could feel 100% confident about your intellect, and never again fear being the person in the room who just isn’t smart enough, or can’t remember something important? How would you treat people if the mood swings, short temper, and food cravings that disrupt your day could simply disappear?In Head Strong, Asprey shows us that all of this is possible—and more. Using his simple lifestyle modifications (or "hacks") to take advantage of how the structure of your brain works, readers will learn how to take their mental performance to the next level. Combining the latest findings in neuroscience and neurobiology with a hacker-inspired "get it done now" perspective, Asprey offers a program structured around key areas of brain performance that will help you:Power the brain with exactly what it needs to perform at its best all day longEliminate the sources of "kryptonite," both nutritional and environmental, that make the brain slower.Supercharge the cellular powerhouses of our brains, the mitochondria, to eliminate cravings and turn up mental focus.Reverse inflammation to perform better right now, then stay sharp and energized well into your golden years.Promote neuron growth to enhance processing speed and reinforce new learning—hotwiring your brain for success.Asprey’s easy to follow, two-week program offers a detailed plan to supercharge brain performance, including: which foods to eat and which ones to avoid, how to incorporate the right kinds of physical activity into your day, a detox protocol for your home and body; meditation and breathing for performance, recommended brain-boosting supplements; and how to adjust the lighting in your home and work space to give your brain the quality light it thrives on.A better brain—and a happier, easier, more productive life—is within reach. You just need to get Head Strong.