The awesome journey of life's transformation from the first microbes 4 billion years ago to Homo sapiens today is an epic that we are only now beginning to grasp. Magnificent and bizarre, it is the story of how we got here, what we left behind, and what we brought with us. We all know about evolution, but it still seems absurd that our ancestors were fish. Darwin's idea of natural selection was the key to solving generation-to-generation evolution -- microevolution -- but it could only point us toward a complete explanation, still to come, of the engines of macroevolution, the transformation of body shapes across millions of years. Now, drawing on the latest fossil discoveries and breakthrough scientific analysis, Carl Zimmer reveals how macroevolution works. Escorting us along the trail of discovery up to the current dramatic research in paleontology, ecology, genetics, and embryology, Zimmer shows how scientists today are unveiling the secrets of life that biologists struggled with two centuries ago. In this book, you will find a dazzling, brash literary talent and a rigorous scientific sensibility gracefully brought together. Carl Zimmer provides a comprehensive, lucid, and authoritative answer to the mystery of how nature actually made itself.

    The 10,000 Year Explosion: How Civilization Accelerated Human Evolution

    For the alternate cover edition by Simon & Schuster, see hereClear and concise explanations of the development of theories explaining physical phenomena.

    The Grand Question of Lifes Origins 2. The Historical Setting of Origins Research 3. What Is Life? 4. Is There Life on Mars? 5. Earths Oldest Fossils 6. Fossil Isotopes 7. Molecular Biosignatures 8. Emergence 9. The Miller-Urey Experiment 10. Life from the Bottom of the Sea 11. The Deep, Hot Biosphere 12. Experiments at High Pressure 13. More Experiments Under Pressure 14. Deep Space Dust, Molten Rock, and Zeolite 15. Macromolecules and the Tree of Life 16. Lipids and Membrane Self-Organization 17. Life on Clay, Clay as Life 18. Lifes Curious Handedness 19. Self-Replicating Molecular Systems 20. Günter Wächtershäusers Grand Hypothesis 21. The RNA World 22. The Pre-RNA World 23. Natural Selection and Competition 24. Three Scenarios for the Origin of Life

    These transitions include the origin of life itself, the first eukaryotic cells, reproduction by sexual means, the appearance ofmulticellular plants and animals, the emergence of cooperation and of animal societies, and the unique language ability of humans. This ambitious book provides the first unified discussion of the full range of these transitions. The authors highlight the similarities between differenttransitions--between the union of replicating molecules to form chromosomes and of cells to form multicellular organisms, for example--and show how understanding one transition sheds light on others. They trace a common theme throughout the history of evolution: after a major transition someentities lose the ability to replicate independently, becoming able to reproduce only as part of a larger whole. The authors investigate this pattern and why selection between entities at a lower level does not disrupt selection at more complex levels. Their explanation encompasses a compellingtheory of the evolution of cooperation at all levels of complexity. Engagingly written and filled with numerous illustrations, this book can be read with enjoyment by anyone with an undergraduate training in biology. It is ideal for advanced discussion groups on evolution and includes accessiblediscussions of a wide range of topics, from molecular biology and linguistics to insect societies.

    But evolutionary biologists also point out many examples of contingency, cases where the tiniest change--a random mutation or an ancient butterfly sneeze--caused evolution to take a completely different course. What role does each force really play in the constantly changing natural world? Are the plants and animals that exist today, and we humans ourselves, inevitabilities or evolutionary freaks? And what does that say about life on other planets?Jonathan Losos reveals what the latest breakthroughs in evolutionary biology can tell us about one of the greatest ongoing debates in science. He takes us around the globe to meet the researchers who are solving the deepest mysteries of life on Earth through their work in experimental evolutionary science. Losos himself is one of the leaders in this exciting new field, and he illustrates how experiments with guppies, fruit flies, bacteria, foxes, and field mice, along with his own work with anole lizards on Caribbean islands, are rewinding the tape of life to reveal just how rapid and predictable evolution can be.Improbable Destinies will change the way we think and talk about evolution. Losos's insights into natural selection and evolutionary change have far-reaching applications for protecting ecosystems, securing our food supply, and fighting off harmful viruses and bacteria. This compelling narrative offers a new understanding of ourselves and our role in the natural world and the cosmos.

    Also included are sections from a copy of Down and Out in Paris and London with handwritten annotations by Orwell indicating how much of the book is based on real events. Michael Shelden is the author of Friends of Promise: Cyril Connolly and the World of Horizon.

    . . and has never been convicted of racketeering, drug-trafficking or murder.Prize-winning journalists John Cummings and Ernest Volkman's shocking true account of the brutal and meteoric rise of John "Johhny Boy" Gotti from Brooklyn "bone-breaker" to lord of the Gambino Family -- a riveting exploration into the the bloody machinery of La Cosa Nostra operating on the dark side of the American dream.

    Rene Descartes discusses the basic rules he has devised to guide human thought toward better knowledge.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    A simple, eloquent description of his 1856-1863 study of the inheritance of traits in pea plants--Mendel analyzed 29,000 of them--this is essential reading for biology students and readers of science history.

    This essay by Copernicus (1473-1543), revolutionized the way we look at the earth's placement in the universe, and paved the way for many great scientists, including Galileo and Isaac Newton, whose theories stemmed from this model. Featuring a biography of Copernicus and an accessible, enlightening introduction, both written by the renowned physicist Stephen Hawking, On the Revolution of Heavenly Spheres provides a fascinating look at the theories which shaped our modern understanding of astronomy and physics.

    His fame was such that many Greek medical writings became attributed to him. What they have in common is not dogma but, rather, constructive debate between one another. They also share a concern with meticulous observation and an insistence on physical, not supernatural, causation of illness. The writers were the pioneers of rational medicine; their ideas, dominant for centuries, still reveal to us the ideal of ethical practice, as well as the origins not just of Western medicine but of scientific method.This excellent selection of Hippocratic treatises shows the range of writing and thought. Some are technical works on embryology, surgery or anatomy; others are addressed to a lay audience; all are informed with the spirit of inquiry. G.E.R. Lloyd's authoritative introduction puts them into their contemporary context and assesses their later influence.

    The last few years have also seen the invention and marketing of new schlock--like pills that claim to eliminate cellulite or burn extra carbohydrates and machines that purport to tone your thighs "without any effort on your part." It's all too easy to get confused by all the myths and mixed messages out there. But don't sweat it! This thoroughly revised edition of Fitness For Dummies updates you on all the latest--the good, the bad, and the bizarre--tackles your fears about getting fit, and gives you the knowledge and motivation to stick with fitness for the rest of your life. Renowned fitness experts Suzanne Schlosberg and Liz Neporent show you how to:Test your fitness level and set realistic goals Pinpoint fat sources in your diet Create a personalized fitness program Find Internet fitness forums and Web sites Brave a public gym This is your essential get-fit guide, covering state-of-the-art fitness techniques, equipment, programs, and health clubs in a practical, friendly way. You'll see how your individualized fitness program will help you strengthen your heart and lungs, burn lots of calories, lower your stress level, and even help you stay injury-free. You get the latest on low-carb eating, new food pyramids, the glycemic index and trans fats, and new carb guidelines. Plus, you'll see how to:Take advantage of hot trends like Yoga and circuit training Incorporate weight training in your workout Choose the best fitness equipment for your home gym Stay fit at all ages and stages Complete with a list of ten great fitness investments under $100 (and ten fitness ripoffs!) as well as proven ways to stay motivated, Fitness For Dummies, Third Edition is your one-stop guide to a slim, trim new you!

    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.