Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation? In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients—a Biotech Social Contract. Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including: Why doesn’t insurance make drugs affordable? How can we prevent price-jacking of older drugs? Why are drugs more expensive in America than elsewhere? How can we guarantee that all medicines eventually go generic so they are only temporarily expensive? What systemic failures led to the opioid crisis, and how can we prevent the next one? The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.

    Cynthia Barnett does it by telling us the stories of the amazing personalities behind our water wars, the stunning contradictions that allow the wettest state to have the most watered lawns, and the thorough research that makes her conclusions inescapable. Barnett has established herself as one of Florida’s best journalists and Mirage is a must-read for anyone who cares about the future of the state.”—Mary Ellen Klas, Capital Bureau Chief, Miami Herald “Mirage is the finest general study to date of the freshwater-supply crisis in Florida. Well-meaning villains abound in Cynthia Barnett’s story, but so too do heroes, such as Arthur R. Marshall Jr., Nathaniel Reed, and Marjorie Harris Carr. The author’s research is as thorough as her prose is graceful. Drinking water is the new oil. Get used to it.”—Michael Gannon, Distinguished Professor of history, University of Florida, and author of Florida: A Short History “With lively prose and a journalist’s eye for a good story, Cynthia Barnett offers a sobering account of water scarcity problems facing Florida—one of our wettest states—and the rest of the East Coast. Drawing on lessons learned from the American West, Mirage uses the lens of cultural attitudes about water use and misuse to plead for reform. Sure to engage and fascinate as it informs.”—Robert Glennon, Morris K. Udall Professor of Law and Public Policy, University of Arizona, and author of Water Follies: Groundwater Pumping and the Fate of America’s Fresh Waters Part investigative journalism, part environmental history, Mirage reveals how the eastern half of the nation—historically so wet that early settlers predicted it would never even need irrigation—has squandered so much of its abundant freshwater that it now faces shortages and conflicts once unique to the arid West. Florida’s parched swamps and supersized residential developments set the stage in the first book to call attention to the steady disappearance of freshwater in the American East, from water-diversion threats in the Great Lakes to tapped-out freshwater aquifers along the Atlantic seaboard. Told through a colorful cast of characters including Walt Disney, Jeb Bush and Texas oilman Boone Pickens, Mirage ferries the reader through the key water-supply issues facing America and the globe: water wars, the politics of development, inequities in the price of water, the bottled-water industry, privatization, and new-water-supply schemes. From its calamitous opening scene of a sinkhole swallowing a house in Florida to its concluding meditation on the relationship between water and the American character, Mirage is a compelling and timely portrait of the use and abuse of freshwater in an era of rapidly vanishing natural resources.

    It was the U.K.’s worst rail disaster in years. On the morning of October 5, 1999, two rush-hour commuter trains collided just outside London. Hundreds were feared dead. Though he was traveling in the front-most carriage, the novelist Andrew Rosenheim survived the crash. In “The Secrets of Carriage H,” Rosenheim recalls in heart-pounding detail the events of that day and opens up about the emotional rollercoaster that consumed him for months thereafter. Told with the rich textures of a novel and the bare heart of a memoir, “The Secrets of Carriage H” explores the unspoken consequences of survival and offers brutal, sometimes hilarious insight into the human condition. Andrew Rosenheim was born and raised in Chicago, but has lived in England for the last thirty-five years. He worked in publishing for many years at Oxford University Press and then as the Managing Director of Penguin Press. He is the author of seven novels, most recently Fear Itself and The Little Tokyo Informant. His writing has appeared in The Times, The New York Times, the Times Literary Supplement, and many other publications. Married, he lives with his wife and twin daughters near Oxford and is the editor of Kindle Singles in the U.K.Cover design by Evan Twohy.

    Through Abbey's own writings and personal papers, as well as interviews with friends and acquaintances, Bishop gives us a penetrating, compelling, no-holds-barred view of tile life and accomplishments of this controversial figure.

    (We can!)

    Along the way, Bryce eviscerates the ethanol scam. Whether the issue is cost, water consumption, or food prices, corn ethanol is one of the longest-running robberies ever perpetrated on American taxpayers.Consumers concerned about peak oil and the future of global energy supplies need to understand that energy security depends on embracing free markets and the realities of interdependence. Gusher of Lies is illuminating, vital reading.

    As far as the regime’s fault lines are concerned, the evidence presented by the authors shows no reversal, or even narrowing, of these structural dysfunctions in Putin’s third presidential term.Topics covered here include Russia's political economy, political geography, and politics of federalism; the regime, ideology, public opinion, and legitimacy; and potential defeat and radicalization of civil society. Emerging in these pages is a finely textured portrait of a society rife in complexities, contradictions, and postponed but looming crises.

    Photographer Glen Denny was a key figure in this golden age of climbing, capturing pioneering feats on camera while tackling challenging ascents himself.In entertaining short pieces enlivened by his iconic black-and-white images of Yosemite's big wall legends, Denny reveals a young man's coming of age and provides a vivid look at Yosemite’s early climbing culture. He relates such precarious achievements as hauling water in glass gallon jugs up the east face of Washington Column, nailing the 750-foot Rostrum in a punishing heat wave, and dangling overnight on El Capitan’s Dihedral Wall in a lightning storm. Each true tale captures the spirit of historic Camp 4, where Denny and others plan the next big climb while living on the cheap and dodging park rangers.

    Whether you are looking to rev up your real estate business, deciding whether to specialize in commercial or residential real estate, or just interested in refining specific skills, this book is for you. This no-nonsense guide shows you the fun and easy way to become a successful real estate agent. It provides expert advice on acquiring the skills needed to excel and the respect and recognition you'll gain through making sales and generating profit. Soon you'll have all the tools you need to:Prospect your way to listings and sales Build a referral-based clientele Work with expired and FSBO listings Plan and host a successful open house Present and close listing contracts Market yourself and your properties online and in print Negotiate contracts and avoid derailment Stake your competitive position Achieve excellent relationships with clients Spend less time to earn more money This guide features tips and tricks for working with buyers, must-haves for a successful real estate agent, and common pitfalls that can be avoided. Also included is a list of Web sites for real estate agents that are valuable resources for success. With Success as a Real Estate Agent For Dummies, you'll discover how to acquire key skills and get on track for a successful career!

    While the attention of the West has been fixed on the USSR and Eastern Europe, a quieter, cumulative revolution has been taking place in Asia which may have even more profound consequences for world history.

    The author offers a pioneering roadmap to responsible macroeconomics and corporate growth."-Clayton Christensen, Professor of Business Administration, Harvard Business School and author of The Innovator's Dilemma"I hope this book will be able to influence the thought processes of corporations and motivate them to adapt to forthcoming business realities for the sake of their own long-term existence. Besides business leaders, this is a thought-provoking book for the readers who are looking for solutions to capitalism's problems."-Muhammad Yunus, Founder and Managing Director, Grameen Bank, Bangladesh and 2007 Nobel Peace Prize recipient"Capitalism at the Crossroads is a practical manifesto for business in the twenty-first century. Professor Stuart L. Hart provides a succinct framework for managers to harmonize concerns for the planet with wealth creation and unambiguously demonstrates the connection between the two. This book represents a turning point in the debate about the emerging role and responsibility of business in society."-C.K. Prahalad, Ross School of Business, University of Michigan, co-author of Competing for the Future and author of The Fortune at the Bottom of the Pyramid "Stuart Hart was there at the beginning. Years ago when the term 'sustainability' had not yet reached the business schools, Stuart Hart stood as a beacon glowing in the umbrage. It is clear commerce is the engine of change, design the first signal of human intention, and global capitalism is at the crossroads. Stuart Hart is there again; this time lighting up the intersection."-William McDonough, University of Virginia, co-author of Cradle to Cradle"Professor Hart is on the leading edge of making sustainability an understandable and useful framework for building business value. This book brings together much of his insights developed over the past decade. Through case studies and practical advice, he argues powerfully that unlimited opportunities for profitable business growth will flow to those companies that bring innovative technology and solutions to bear on some of the world's most intractable social and environmental problems."-Chad Holliday, Chairman and CEO, DuPont"Capitalism at the Crossroads clearly reveals the essence of what sustainability means to today's business world. Hart's analysis that businesses must increasingly adopt a business framework based on building sustainable value speaks to the entire sustainability movement's relevance. Sustainability is more than today's competitive edge; it is tomorrow's model for success."-Don Pether, President and CEO, Dofasco Inc."Stuart Hart has written a book full of big insights painted with bold strokes. He may make you mad. He will certainly make you think."-Jonathan Lash, President, The World Resources Institute"A must-read for every CEO--and every MBA."-John Elkington, Chairman, SustainAbility"This book provides us with a vast array of innovative and practical ideas to accelerate the transformation to global sustainability and the role businesses and corporations will have to play therein. Stuart Hart manages to contribute in an essential way to the growing intellectual capital that addresses this topic. But, beyond that, the book will also prove to be a pioneer in the literature on corporate strategy by adding this new dimension to the current thinking."-Jan Oosterveld, Professor, IESE Business School, Barcelona, Spain Member, Group Management Committee (Ret.), Royal Philips Electronics"Capitalism at the Crossroads captures a disturbing and descriptive picture of the global condition. Dr. Hart constructs a compelling new corporate business model that simultaneously merges the metric of profitability along with societal value and environmental integrity. He challenges the corporate sector to take the lead and to invoke this change so that the benefits of capitalism can be shared with the entire human community worldwide."-Mac Bridger, CEO of Tandus Group"Stuart L. Hart makes a very important contribution to the understanding of how enterprise can help save the world's environment. Crucial reading."-Hernando de Soto, President of The Institute for Liberty and Democracy and author of The Mystery of Capital"Stuart Hart's insights into the business sense of sustainability come through compellingly in Capitalism at the Crossroads. Any businessperson interested in the long view will find resonance with his wise reasoning."-Ray Anderson, Founder and Chairman, Interface, Inc."This stimulating book documents the central role that business will play in humanity's efforts to develop a sustainable global economy. Professor Hart presents an attractive vision of opportunity for those corporations that develop the new technologies, new business models, and new mental frames that are essential to a sustainable future."-Jeffrey Lehman, Former President of Cornell University"The people of the world are in desperate need of new ideas if global industrial development is ever to result in something other than the rich getting richer and the poor getting poorer, with nature (and potentially all of us) suffering the collateral damage. Few have contributed more to meeting this need over the past decade than Stuart Hart by helping to illuminate the potential role for business and new thinking in business strategy in the journey ahead. Capitalism at the Crossroads challenges, provokes, and no doubt will stimulate many debates--which is exactly what is needed."-Peter Senge, Massachusetts Institute of Technology, Chairperson of the Society for Organizational Learning, and author of The Fifth Discipline: The Art and Practice of The Learning OrganizationNew Foreword by Al Gore Brand-New Second Edition, Completely Revised with: Up-to-the-minute trends and lessons learned New and updated case studies The latest corporate responses to climate change, energy, and terrorism Global capitalism stands at a crossroads-facing terrorism, environmental destruction, and anti-globalization backlash. Today's global companies are at a crossroads, too-searching desperately for new sources of profitable growth. Stuart L. Hart's Capitalism at the Crossroads, Second Edition is about solving both of those problems at the same time.It's about igniting new growth by creating sustainable products that solve urgent societal problems. It's about using new technology to deliver profitable solutions that reduce poverty and protect the environment. It's about becoming truly indigenous to all your markets, and avoiding the pitfalls of first-generation "greening" and "sustainability" strategies.Hart has thoroughly revised this seminal book with new case studies, trends, and lessons learned-including the latest experiences of leaders like GE and Wal-Mart. You'll find new insights from the pioneering BoP Protocol initiative, in which multinationals are incubating new businesses in income-poor communities. You'll also discover creative new ways in which corporations are responding to global warming and terrorism. More than ever, this book points the way toward a capitalism that's more inclusive, more welcome, and far more successful-for both companies and communities, worldwide.Paths to profitable sustainability: Lessons from GE and Wal-Mart Shattering the "trade-off" myth New commercial strategies for serving the "base of the pyramid" What enterprises have learned about doing business in income-poor regions Becoming indigenous-for real, for good Codiscovering new opportunities, cocreating new businesses with the poor Learning from leaders: 20+ new and updated case studies Best practices from DuPont, HP, Unilever, SC Johnson, Tata, P&G, Cemex, and more About the Author xiiAcknowledgments xiiiForeword: Al Gore, Former Vice President of the U.S. xxivForeword: Fisk Johnson, Chairman and CEO, S.C. Johnson & Son, Inc. xxviiPrologue: Capitalism at the Crossroads xxxiPART ONE: MAPPING THE TERRAIN Chapter 1: From Obligation to Opportunity 3Chapter 2: Worlds in Collision 31Chapter 3: The Sustainable Value Portfolio 59PART TWO: BEYOND GREENING Chapter 4: Creative Destruction and Sustainability 87Chapter 5: The Great Leap Downward 111Chapter 6: Reaching the Base of the Pyramid 139PART THREE: BECOMING INDIGENOUS Chapter 7: Broadening the Corporate Bandwidth 169Chapter 8: Developing Native Capability 193Chapter 9: Toward a Sustainable Global Enterprise 223Epilogue 249Index 254

    The classic account of modern British journalism, now updated and re-issued.

    Michael Savage explains the origins of viruses and their impact on the U.S. With new and resurgent diseases resulting from unregulated immigration and a politicized public health system, Michael Savage sees the need for some changes - starting with the President and the Center for Disease Control telling us the truth. Savage makes his case for the government to enforce travel bans, the use of quarantines and the importance of proper border screenings. However, this is not a cure or treatment for any of these diseases. With Zika virus, tuberculosis, hepatitis, Enterovirus 68 and other new disease threats emerging across the U.S., Savage will explain ways to fortify your immune system and defend against these and other diseases. Drawing from his extensive training, Dr. Savage examines the benefits of using specific nutrients to boost the human immune system which, in turn, increases the odds of surviving a viral infection as well as preventing other diseases. Based on his knowledge of the politics of medicine being played by the Obama mandarins and his Ph.D. in Epidemiology and Nutrition from the University of California, Berkley, Dr. Savage presents solid information to protect your health. Whether you want to defend your body against deadly diseases, boost your immunity, or learn more about the government's impact on reemerging and imported diseases, DISEASES WITHOUT BORDERS is your source for informative, helpful, and potentially life-saving advice.

    King Hubbert predicted in 1956 that U.S. oil production would reach its highest level in the early 1970s. Though roundly criticized by oil experts and economists, Hubbert's prediction came true in 1970.In this revised and updated edition reflecting the latest information on the world supply of oil, Kenneth Deffeyes uses Hubbert's methods to find that world oil production will peak in this decade--and there isn't anything we can do to stop it. While long-term solutions exist in the form of conservation and alternative energy sources, they probably cannot--and almost certainly will not--be enacted in time to evade a short-term catastrophe.

    The cases in the 15th edition are excerpted and edited by the authors. The syntax is not altered, therefore retains the language of the courts. As in recent previous editions, the 15th edition includes a mix of actual AND hypothetical cases. This text is our most research-based Business Law text.