Translated into eight languages, it is an essential textbook, an accessible reference, and a bestselling text worldwide.This authoritative textbook retains the successful layout and approach of the bestselling fourth edition Four extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.Each chapter have been updated and expanded and the number of illustrations greatly increased.Over a third of the illustrations are new for this editionFour extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.The contents of each chapter have been updated and expanded and the number of illustrations has significantly increased.

    Cole's harrowing account of his life spent in the ER and on the battlegrounds, fighting to save lives. In addition to his gripping stories of treating victims of gunshot wounds, stabbings, attempted suicides, flesh-eating bacteria, car crashes, industrial accidents, murder, and war, the book also covers the years during Cole's residency training when he was faced with 120-hour work weeks, excessive sleep deprivation, and the pressures of having to manage people dying of traumatic injury, often with little support.  Unlike the authors of other medical memoirs, Cole trained to be a surgeon in the military and served as a physician member of a Marine Corps reconnaissance unit, United States Special Operations Command (USSOCOM), and on a Navy Reserve SEAL team.  From treating war casualties in Afghanistan and Iraq to his experiences as a civilian trauma surgeon treating alcoholics, drug addicts, criminals, and the mentally deranged, TRAUMA is an intense look at one man's commitment to his country and to those most desperately in need of aid.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Dumb crooks, celebrities gone bad, unsolved mysteries, odd laws, and more—Strange Crime has plenty of stories that will make you ask yourself, “What could they possibly have been thinking?” This easily portable paperback book is ideal for readers on the go. Take it to school, to work, to jury duty!

    She takes us to the ultra-bizarre Body Farm in Knoxville, Tennessee, where scientists watch bodies decay in order to learn the secrets of decomposition and death. She also takes us into the courtroom, where "post-O. J." forensic science as a whole is coming under fire and the new multidisciplinary art of forensic ecology is struggling to establish its credibility." In the end, Sachs reveals death to be not a single moment in time, but an elaborate dance, as insects and microbes colonize a corpse, and efficiently - even gracefully - return it to the earth. The story of the 2000-year search to pinpoint time of death. Corpse is also the terrible and beautiful story of what happens to our bodies when we die.

    As one of the UK’s leading forensic scientists, Mike Silverman has helped to identify and convict dozens of murderers, rapists, armed robbers, burglars and muggers, thanks to the evidence they – or their victims – unwittingly left behind at the scenes of their crimes.Mike Silverman started his career in the days when fingerprints were still kept on card files and DNA profiling was just a pipe dream, so Written in Blood is more than just a casebook – it is also a definitive history of the development of forensic science over the course of the past thirty-five years.From collecting blood samples at gangland executions to investigating forensic science failings, including in the murders of Rachel Nickell and Damilola Taylor, Mike Silverman’s unique career provides a fascinating insight into the ways forensic science is used to help solve real-life crimes.Packed with genuine crime scene photographs and original sketches, Written in Blood is the ultimate insider’s account of the fascinating world of forensic science.

    In this absorbing, surprising, and undeniably compelling book, forensics expert Emily Craig tells her own story of a life spent teasing secrets from the dead.Emily Craig has been a witness to history, helping to seek justice for thousands of murder victims, both famous and unknown. It's a personal story that you won't soon forget.Emily first became intrigued by forensics work when, as a respected medical illustrator, she was called in by the local police to create a model of a murder victim's face. Her fascination with that case led to a dramatic midlife career change: She would go back to school to become a forensic anthropologist——and one of the most respected and best-known "bone hunters" in the nation.As a student working with the FBI in Waco, Emily helped uncover definitive proof that many of the Branch Davidians had been shot to death before the fire, including their leader, David Koresh, whose bullet-pierced skull she reconstructed with her own hands. Upon graduation, Emily landed a prestigious full-time job as forensic anthropologist for the Commonwealth of Kentucky, a state with an alarmingly high murder rate and thousands of square miles of rural backcountry, where bodies are dumped and discovered on a regular basis. But even with her work there, Emily has been regularly called to investigations across the country, including the site of terrorist attack on the the Murrah Building in Oklahoma City, where a mysterious body part——a dismembered leg——was found at the scene and did not match any of the known victims. Through careful scientific analysis, Emily was able to help identify the leg's owner, a pivotal piece of evidence that helped convict Timothy McVeigh.In September 2001, Emily recieved a phone call summoning her to New York City, where she directed the night-shift triage at the World Trade Centre's body identification site, collaborating with forensics experts from all over the country to collect and identify the remains of September 11 victims.From the biggest new stories of our time to stranger-than-true local mysteries, these are unforgettable stories from the case files of Emily Craig's remarkable career.

    If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

    Vincent DiMaio and veteran crime writer Ron Franscell guide us behind the morgue doors to tell a fascinating life story through the cases that have made Di Maio famous-from the exhumation of assassin Lee Harvey Oswald to the complex issues in the shooting of Florida teenager Trayvon Martin.Beginning with his street-smart Italian origins in Brooklyn, the book spans 40 years of work and more than 9,000 autopsies, and Di Maio's eventual rise into the pantheon of forensic scientists. One of the country's most methodical and intuitive criminal pathologists will dissect himself, maintaining a nearly continuous flow of suspenseful stories, revealing anecdotes, and enough macabre insider details to rivet the most fervent crime fans.

    With a muckraker's passion, Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. Tracing over three centuries of "cures" for madness, Whitaker shows how medical therapies have been used to silence patients and dull their minds. He tells of the eighteenth- and nineteenth-century practices of "spinning" the insane, extracting their teeth, ovaries, and intestines, and submerging patients in freezing water. The "cures" in the 1920s and 1930s were no less barbaric as eugenic attitudes toward the mentally ill led to brain-damaging lobotomies and electroshock therapy. Perhaps Whitaker's most damning revelation, however, is his report of how drug companies in the 1980s and 1990s skewed their studies in an effort to prove the effectiveness of their products. Based on exhaustive research culled from old patient medical records, historical accounts, numerous interviews, and hundreds of government documents, Mad in America raises important questions about our obligations to the mad, what it means to be "insane," and what we value most about the human mind.

    - Book Review Editor of the journal "Modern Pathology," the official journal of the United States-Canadian Academy of Pathology and prestigious best-selling author. This is the 5th edition of a book that has already established itself as the classic pathology textbook in India. This new edition has been updated, and improved to meet the highest standards of quality and information now required by pathology courses around the world. Editorially this new edition carries particular emphasis on molecular pathology and genetics in the pathogenesis of various diseases, and the pathological discussions of each organ or system is preceded with a short description of its structure and function. The material is integrated with extensive page cross references between chapters and the whole book has been thoroughly re-edited, with new images, illustrations and line drawings. The book is accompanied by the free student revision aid "Pathology - Quick Review and MCQs" and therefore, together as a package, "Textbook of Pathology, 5E" will be a major contribution to the required reading of undergraduate medical students worldwide.

    But as renowned Yale surgeon and medical historian Sherwin B. Nuland shows in this brilliant collection of linked life portraits, the theory bears little resemblance to the truth. Through the centuries, the men and women who have shaped the world of medicine have been not only very human, but also very much the products of their own times and places. Presenting compelling studies of great medical innovators and pioneers, Doctors gives us a fascinating history of modern medicine. Ranging from the legendary Father of Medicine, Hippocrates, to Andreas Vesalius, whose Renaissance masterwork on anatomy offered invaluable new insight into the human body, to Helen Taussig, founder of pediatric cardiology and co-inventor of the original blue baby operation, here is a volume filled with the spirit of ideas and the thrill of discovery.

    Created primarily for medical and premedical students, 'Neuroscience' emphasizes the structure of the nervous system, the correlation of structure and function, and the structure/function relationships particularly pertinent to the practice of medicine.

    As the current CEO of Children's National in Washington, D.C., the author presents an argument to place children's medical requirements and their need to thrive well into adulthood at the forefront of American medicine, and he admits that 'these kids have been my real teachers

    Until, at the tender age of sixteen, he worked out how to use the credit card system to his advantage. Identifying the banks' security weaknesses, utilising his intelligence and charm, Elliot embarked on a massive spending spree. From London to New York, Ibiza to Beverly Hills, he lived the fantasy life, staying in famous hotels, flying first class, blowing a fortune on designer clothes. Time and time again, Elliot managed to wriggle free of the numerous authorities who were on his tail, while his life spiralled out of control. Meanwhile, from a police station at Heathrow, a detective was patiently tracking him down . . . With a likeable hero, filled with humour and as fast-paced as a thriller, Other People's Money is crime writing at its best.'A fascinating and illuminating story' Irvine Welsh'Exhilarating Brit variation on Catch Me if You Can, which never misses an opportunity to up the sweaty-palmed suspense.' "Arena"