In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me.

    But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still... until now. In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycle of stress, inflammation and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into the story of Western medicine, how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future.

    Under favorable circumstances, this process results in emotional healing, a radical shift in values, and a profound awareness of the mystical dimension of existence. For some, these changes are gradual and relatively smooth, but for others they can be so rapid and dramatic that they interfere with effective everyday functioning, creating tremendous inner turmoil. Unfortunately, many traditional health-care professionals do not recognize the positive potential of these crises; they often see them as manifestations of mental disease and repsond with stigmatizing labels, suppressive drugs, and even institutionalization.In The Stormy Search for the Self, Christina and Stanislav Grof, the world's foremost authorities on the subject of spiritual emergence, draw on years of dramatic personal and professional experience with transformative states to explore these "spiritual emergencies," altered states so powerful they threaten to overwhelm the individual's oridinary reality. This book will provide insights, assurances, and practical suggestions for those who are experiencing or have experienced such a crisis, for their families and friends, and for mental-health professionals. It is also a valuable guide for anyone involved in personal transformation whose experiences, though generally untraumatic, may still at times be bewildering or disorienting.

    Ranging from the depths of the ocean to the most arid corners of the land, Caspar Henderson captures the beauty and bizzareness of the many living forms we thought we knew and some we could never have contemplated, inviting us to better imagine the precarious world we inhabit.A witty, vivid blend of cutting edge natural history and meditative reflections, The Book of Barely Imagined Beings is infectious and celebratory about the sheer ingenuity and variety of life.

    The implications of this revolutionary scientific paradigm extend into virtually every aspect of our psychology, our history and culture, our religion -- and indeed our future.

    In this unique combination of biological science and philosophical interrogation, Raymond Tallis takes the head apart, piece by piece, in search of the place where our souls, and consciousness, reside.From the act of blushing and the amount of manganese in our tears (tears of pain contain more than tears of distress) to the curiousness of a kiss, "The Kingdom of Infinite Space" explores the astonishing range of activities that go on inside our heads, most of which are entirely beyond our control. After escorting his readers on a fantastic voyage through every chamber of the head and brain, Raymond Tallis demonstrates that not only does consciousness not reside between our ears, but that our heads are infinitely cleverer than we are.

    How did the replication bomb we call ”life” begin and where in the world, or rather, in the universe, is it heading? Writing with characteristic wit and an ability to clarify complex phenomena (the New York Times described his style as ”the sort of science writing that makes the reader feel like a genius”), Richard Dawkins confronts this ancient mystery.

    With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds.Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.

    As a student and young researcher in the 1980s, Gelernter hoped to build a program with a dial marked "focus." At maximum "focus," the program would "think" rationally, formally, reasonably. As the dial was turned down and "focus" diminished, its "mind" would start to wander, and as you dialed even lower, this artificial mind would start to free-associate, eventually ignoring the user completely as it cruised off into the mental adventures we know as sleep.While the program was a only a partial success, it laid the foundation for The Tides of Mind, a groundbreaking new exploration of the human psyche that shows us how the very purpose of the mind changes throughout the day. Indeed, as Gelernter explains, when we are at our most alert, when reasoning and creating new memories is our main mental business, the mind is a computer-like machine that keeps emotion on a short leash and attention on our surroundings. As we gradually tire, however, and descend the "mental spectrum," reasoning comes unglued. Memory ranges more freely, the mind wanders, and daydreams grow more insistent. Self-awareness fades, reflection blinks out, and at last we are completely immersed in our own minds.With far-reaching implications, Gelernter’s landmark "Spectrum of Consciousness" finally helps decode some of the most mysterious wonders of the human mind, such as the numinous light of early childhood, why dreams are so often predictive, and why sadism and masochism underpin some of our greatest artistic achievements. It’s a theory that also challenges the very notion of the mind as a machine—and not through empirical studies or "hard science" but by listening to our great poets and novelists, who have proven themselves as humanity's most trusted guides to the subjective mind and inner self.In the great introspective tradition of Wilhelm Wundt and René Descartes, David Gelernter promises to not only revolutionize our understanding of what it means to be human but also to help answer many of our most fundamental questions about the origins of creativity, thought, and consciousness.

     A powerful, heart-warming and inspiring memoir from the UK's most famous and beloved vet, Professor Noel Fitzpatrick - star of the Channel 4 series The Supervet. Growing up on the family farm in Ballyfin, Ireland, Noel's childhood was spent tending to the cattle and sheep, the hay and silage, the tractors and land, his beloved sheepdog Pirate providing solace from the bullies that plagued him at school. It was this bond with Pirate, and a fateful night spent desperately trying to save a newborn lamb, that inspired Noel to enter the world of veterinary science - and set him on the path to becoming The Supervet.Now, in this long-awaited memoir, Noel recounts this often-surprising journey that sees him leaving behind a farm animal practice in rural Ireland to set up Fitzpatrick Referrals in Surrey, one of the most advanced small animal specialist centres in the world. We meet the animals that paved the way, from calving cows and corralling bullocks to talkative parrots and bionic cats and dogs. Noel has listened to the many lessons that the animals in his care have taught him, and especially the times he has shared with his beloved Keira, the scruffy Border Terrier who has been by Noel's side as he's dealt with the unbelievable highs and crushing lows of his extraordinary career. As heart-warming and life-affirming as the TV show with which he made his name, Listening to the Animals is a story of love, hope and compassion, and about rejoicing in the bond between humans and animals that makes us the very best we can be.

    But what are the real needs that must be satisfied to live rich, fulfilling lives? This is the question David Suzuki explores in this wide-ranging study. Suzuki begins by presenting the concept of people as creatures of the Earth who depend on its gifts of air, water, soil, and sun energy. He shows how people are genetically programmed for the company of other species, and suffer enormously when we fail to live in harmony with them. And he analyzes those deep spiritual needs, rooted in nature, that are also a crucial component of a loving world. Drawing on his own experiences and those of others who have put their beliefs into action, The Sacred Balance is a powerful, passionate book with concrete suggestions for creating an ecologically sustainable, satisfying, and fair future by rediscovering and addressing humanity’s basic needs.

    He shows how many intellectuals have denied the existence of human nature by embracing three linked dogmas: the Blank Slate (the mind has no innate traits), the Noble Savage (people are born good and corrupted by society), and the Ghost in the Machine (each of us has a soul that makes choices free from biology). Each dogma carries a moral burden, so their defenders have engaged in desperate tactics to discredit the scientists who are now challenging them.Pinker injects calm and rationality into these debates by showing that equality, progress, responsibility, and purpose have nothing to fear from discoveries about a rich human nature. He disarms even the most menacing threats with clear thinking, common sense, and pertinent facts from science and history.Despite its popularity among intellectuals during much of the twentieth century, he argues, the doctrine of the Blank Slate may have done more harm than good. It denies our common humanity and our individual preferences, replaces hardheaded analyses of social problems with feel-good slogans, and distorts our understanding of government, violence, parenting, and the arts.Pinker shows that an acknowledgement of human nature that is grounded in science and common sense, far from being dangerous, can complement insights about the human condition made by millennia of artists and philosophers. All this is done in the style that earned his previous books many prizes and worldwide acclaim: wit, lucidity, and insight into matters great and small.

    With his own research as well as that of some of the most distinguished scientists of our time, Schäfer moves us from a reality of Darwinian competition to cooperation, a meaningless universe to a meaningful one, and a disconnected, isolated existence to an interconnected one. In so doing, he shows us that our potential is infinite and calls us to live in accordance with the order of the universe, creating a society based on the cosmic principle of connection, emphasizing cooperation and community.

    After acquiring Brenin as a cub, it quickly became apparent that Brenin was never to be left alone, as the consequences to Mark’s house and its contents were dire. As a result, Brenin and Mark went everywhere together—from classroom lecture to Ireland, England, and France. More than just an exotic pet, Brenin exerted an immense influence on Rowlands as both a person, and, strangely enough, as a philosopher, leading him to re-evaluate his attitude to love, happiness, nature and death. By turns funny (what do you do when your wolf eats your air-conditioning unit?) and poignant, this life-affirming book will make you reappraise what it means to be human.

    Drawing on new translations of Mutis's nearly forgotten writings, this fascinating story of scientific adventure in eighteenth-century South America retrieves Mutis's contributions from obscurity.In 1760, the 28-year-old Mutis—newly appointed as the personal physician of the Viceroy of the New Kingdom of Granada—embarked on a 48-year exploration of the natural world of northern South America. His thirst for knowledge led Mutis to study the region's flora, become a professor of mathematics, construct the first astronomical observatory in the Western Hemisphere, and amass one of the largest scientific libraries in the world. He translated Newton's writings and penned essays about Copernicus; lectured extensively on astronomy, geography, and meteorology; and eventually became a priest. But, as two-time Pulitzer Prize–winner Edward O. Wilson and Spanish natural history scholar José M. Gómez Durán reveal in this enjoyable and illustrative account, one of Mutis's most magnificent accomplishments involved ants.Acting at the urging of Carl Linnaeus—the father of taxonomy—shortly after he arrived in the New Kingdom of Granada, Mutis began studying the ants that swarmed everywhere. Though he lacked any entomological training, Mutis built his own classification for the species he found and named at a time when New World entomology was largely nonexistent. His unorthodox catalog of army ants, leafcutters, and other six-legged creatures found along the banks of the Magdalena provided a starting point for future study.Wilson and Durán weave a compelling, fast-paced story of ants on the march and the eighteenth-century scientist who followed them. A unique glance into the early world of science exploration, Kingdom of Ants is a delight to read and filled with intriguing information.