By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Before he was “Babe” or “The Sultan of Swat” or “The Great Bambino”, George Herman Ruth was just another teenage misfit at St. Mary’s School for Boys. But Ruth has something the other boys don’t, and when Baltimore Orioles manager Jack Dunn watches him throw a baseball over a building, Ruth gets the chance to punch his ticket out of the orphanage. All he has to do now is make the team. For help navigating life in the Minor Leagues, good-natured Ruth is paired with another rookie, one Jack Dunn, Jr., the coach’s son. Even though they’re the same age, Ruth looks up to his new pal and roommate. But despite his encyclopedic knowledge of the game and austere work ethic, “Junior” (as his teammates mockingly refer to him) can’t field a ground ball to save his life. When Babe makes the roster and Junior doesn’t, their budding friendship feels the strain. As Ruth’s otherworldly on-field abilities - and cringeworthy off-field antics - become the focus of the Orioles’ best season yet, jealous Junior resolves to sabotage the naïve and unsuspecting Babe. It’s a choice that could prove catastrophic for not only the young phenom, but also Junior, his father and the entire sport of baseball. Told from Babe’s point of view, the hilarious and heart-felt Screwball is a classic story of friendship, envy and a legend in the making that listeners will find impossible not to love.

    But what if our actions are driven not by our conscious values and beliefs but by hidden motivations we’re not even aware of?The “hidden brain” is Shankar Vedantam’s shorthand for a host of brain functions, emotional responses, and cognitive processes that happen outside our conscious awareness but have a decisive effect on how we behave. The hidden brain has its finger on the scale when we make all our most complex and important decisions: It decides whom we fall in love with, whether we should convict someone of murder, and which way to run when someone yells “Fire!” It explains why we can become riveted by the story of a single puppy adrift on the ocean but are quickly bored by a story of genocide. The hidden brain can also be deliberately manipulated to convince people to vote against their own interests, or even become suicide terrorists. But the most disturbing thing is that it does all this without our knowing.Shankar Vedantam, author of The Washington Post’s popular “Department of Human Behavior” column, takes us on a tour of this phenomenon and explores its consequences. Using original reporting that combines the latest scientific research with compulsively readable narratives that take readers from the American campaign trail to terrorist indoctrination camps, from the World Trade Center on 9/11 to, yes, a puppy adrift on the Pacific Ocean, Vedantam illuminates the dark recesses of our minds while making an original argument about how we can compensate for our blind spots and what happens when we don’t.

    This perspective leads to therapies focused on ridding individuals of autistic symptoms. In Uniquely Human, Dr. Barry M. Prizant suggests a major shift in understanding autism: Instead of classifying "autistic" behaviors as signs of pathology, he sees them as strategies to cope with a world that feels chaotic and overwhelming. Rather than curb these behaviors, it's better to enhance abilities, build on strengths, and offer supports that will naturally lead to more desirable behavior and a better quality of life. In fact, argues Dr. Prizant, attempts to eliminate autistic behaviors may actually interfere with important developmental processes.Including inspiring stories and practical advice drawn from Dr. Prizant's four-decade career working in universities, schools, hospitals, and in private practice, Uniquely Human offers a compassionate and insightful perspective that parents, professionals, and family members will find uplifting and hopeful.

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    In fact, your body is actually endowed with many self-defense measures to hold on to fat. For example, fat can use stem cells to regenerate; increase our appetite if it feels threatened; and use bacteria, genetics, and viruses to expand itself. The secret to losing twenty pounds? You have to work with your fat, not against it. Tara explains how your fat influences your appetite and willpower, how it defends itself when attacked, and why it grows back so quickly. The Secret Life of Fat brings cutting-edge research together with historical perspectives to reveal fat’s true identity: an endocrine organ that, in the right amount, is critical to our health. Fat triggers puberty, enables our reproductive and immune systems, and even affects brain size.Although we spend $60 billion annually fighting fat, our efforts are often misinformed and misdirected. Tara expertly illustrates the complex role that genetics, hormones, diet, exercise, and history play in our weight, and The Secret Life of Fat sets you on the path to beat the bulge once and for all.

    In Wicked Plants, Stewart takes on over two hundred of Mother Nature’s most appalling creations. It’s an A to Z of plants that kill, maim, intoxicate, and otherwise offend. You’ll learn which plants to avoid (like exploding shrubs), which plants make themselves exceedingly unwelcome (like the vine that ate the South), and which ones have been killing for centuries (like the weed that killed Abraham Lincoln's mother). Menacing botanical illustrations and splendidly ghastly drawings create a fascinating portrait of the evildoers that may be lurking in your own backyard. Drawing on history, medicine, science, and legend, this compendium of bloodcurdling botany will entertain, alarm, and enlighten even the most intrepid gardeners and nature lovers.

    As Professor of Anatomy and Forensic Anthropology, she focuses on mortal remains in her lab, at burial sites, at scenes of violence, murder and criminal dismemberment, and when investigating mass fatalities due to war, accident or natural disaster. In All that Remains she reveals the many faces of death she has come to know, using key cases to explore how forensic science has developed, and what her work has taught her. Do we expect a book about death to be sad? Macabre? Sue’s book is neither. There is tragedy, but there is also humour in stories as gripping as the best crime novel. Our own death will remain a great unknown. But as an expert witness from the final frontier, Sue Black is the wisest, most reassuring, most compelling of guides.

    And there is no more accomplished and accessible guide than renowned neuroscientist David Eagleman to help us understand the nature and changing texture of that fabric. With his hallmark clarity and enthusiasm he reveals the myriad ways that the brain absorbs experience: developing, redeploying, organizing, and arranging the data it receives from the body's own absorption of external stimuli, which enables us to gain the skills, the facilities, and the practices that make us who we are. Eagleman covers decades of the most important research into the functioning of the brain and presents new discoveries from his own research as well: about the nature of synesthesia, about dreaming, and about wearable devices that are revolutionizing how we think about the five human senses. Finally, Livewired is as deeply informative as it is accessible and brilliantly engaging.

    What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    The public has thus been left to wonder whether he is mad, bad, or both.In THE DANGEROUS CASE OF DONALD TRUMP, twenty-seven psychiatrists, psychologists, and other mental health experts argue that, in Mr. Trump’s case, their moral and civic “duty to warn” America supersedes professional neutrality. They then explore Trump’s symptoms and potentially relevant diagnoses to find a complex, if also dangerously mad, man.Philip Zimbardo and Rosemary Sword, for instance, explain Trump’s impulsivity in terms of “unbridled and extreme present hedonism.” Craig Malkin writes on pathological narcissism and politics as a lethal mix. Gail Sheehy, on a lack of trust that exceeds paranoia. Lance Dodes, on sociopathy. Robert Jay Lifton, on the “malignant normality” that can set in everyday life if psychiatrists do not speak up.His madness is catching, too. From the trauma people have experienced under the Trump administration to the cult-like characteristics of his followers, he has created unprecedented mental health consequences across our nation and beyond.It’s not all in our heads. It’s in his."There will not be a book published this fall more urgent, important, or controversial than The Dangerous Case of Donald Trump...profound, illuminating and discomforting" —Bill Moyers

    Teenage girls are taking courses of testosterone and disfiguring their bodies. Parents are undermined; experts are over-relied upon; dissenters in science and medicine are intimidated; free speech truckles under renewed attack; socialized medicine bears hidden consequences; and an intersectional era has arisen in which the desire to escape a dominant identity encourages individuals to take cover in victim groups. Every person who has ever had a skeptical thought about the sudden rush toward a non-binary future but been afraid to express it—this book is for you.