In the book, Sagan explores 15 billion years of cosmic evolution and the development of science and civilization. Cosmos traces the origins of knowledge and the scientific method, mixing science and philosophy, and speculates to the future of science. The book also discusses the underlying premises of science by providing biographical anecdotes about many prominent scientists throughout history, placing their contributions into the broader context of the development of modern science.The book covers a broad range of topics, comprising Sagan's reflections on anthropological, cosmological, biological, historical, and astronomical matters from antiquity to contemporary times. Sagan reiterates his position on extraterrestrial life—that the magnitude of the universe permits the existence of thousands of alien civilizations, but no credible evidence exists to demonstrate that such life has ever visited earth.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

    But while this medieval medicine now seems archaic, it also made a critical contribution to modern science.Medieval Bodies guides us on a head-to-heel journey through this era’s revolutionary advancements and disturbing convictions. We learn about the surgeons who dissected a living man’s stomach, then sewed him up again; about the geographers who delineated racial groups by skin color; and about the practice of fasting to gain spiritual renown. Encompassing medicine and mysticism, politics and art—and complete with vivid, full-color illustrations—Medieval Bodies shows us how it felt to live and die a thousand years ago.

    And there is no more accomplished and accessible guide than renowned neuroscientist David Eagleman to help us understand the nature and changing texture of that fabric. With his hallmark clarity and enthusiasm he reveals the myriad ways that the brain absorbs experience: developing, redeploying, organizing, and arranging the data it receives from the body's own absorption of external stimuli, which enables us to gain the skills, the facilities, and the practices that make us who we are. Eagleman covers decades of the most important research into the functioning of the brain and presents new discoveries from his own research as well: about the nature of synesthesia, about dreaming, and about wearable devices that are revolutionizing how we think about the five human senses. Finally, Livewired is as deeply informative as it is accessible and brilliantly engaging.

      In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    A strong gravitational wave will briefly change that distance by less than the thickness of a human hair. We have perhaps less than a few tenths of a second to perform this measurement. And we don’t know if this infinitesimal event will come next month, next year or perhaps in thirty years.In 1916 Einstein predicted the existence of gravitational waves: miniscule ripples in the very fabric of spacetime generated by unfathomably powerful events. If such vibrations could somehow be recorded, we could observe our universe for the first time through sound: the hissing of the Big Bang, the whale-like tunes of collapsing stars, the low tones of merging galaxies, the drumbeat of two black holes collapsing into one. For decades, astrophysicists have searched for a way of doing so…In 2016 a team of hundreds of scientists at work on a billion-dollar experiment made history when they announced the first ever detection of a gravitational wave, confirming Einstein’s prediction. This is their story, and the story of the most sensitive scientific instrument ever made: LIGO.Based on complete access to LIGO and the scientists who created it, Black Hole Blues provides a firsthand account of this astonishing achievement: a compelling, intimate portrait of cutting-edge science at its most awe-inspiring and ambitious.

    Dozens died of radiation poisoning, fallout contaminated half the continent, and thousands fell ill.In Chernobyl, Serhii Plokhy draws on new sources to tell the dramatic stories of the firefighters, scientists, and soldiers who heroically extinguished the nuclear inferno. He lays bare the flaws of the Soviet nuclear industry, tracing the disaster to the authoritarian character of the Communist party rule, the regime's control over scientific information, and its emphasis on economic development over all else.Today, the risk of another Chernobyl looms in the mismanagement of nuclear power in the developing world. A moving and definitive account, Chernobyl is also an urgent call to action.

    Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. When the option is a long life with a disease or a short one without it, evolution opts for disease almost every time.Everything from the climate our ancestors lived in to the crops they planted and ate to their beverage of choice can be seen in our genetic inheritance. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives..

    In Helgoland, he examines the enduring enigma of quantum theory. The quantum world Rovelli describes is as beautiful as it is unnerving.Helgoland is a treeless island in the North Sea where the twenty-three-year-old Werner Heisenberg made the crucial breakthrough for the creation of quantum mechanics, setting off a century of scientific revolution. Full of alarming ideas (ghost waves, distant objects that seem to be magically connected, cats that appear both dead and alive), quantum physics has led to countless discoveries and technological advancements. Today our understanding of the world is based on this theory, yet it is still profoundly mysterious.As scientists and philosophers continue to fiercely debate the meaning of the theory, Rovelli argues that its most unsettling contradictions can be explained by seeing the world as fundamentally made of relationships rather than substances. We and everything around us exist only in our interactions with one another. This bold idea suggests new directions for thinking about the structure of reality and even the nature of consciousness.Rovelli makes learning about quantum mechanics an almost psychedelic experience. Shifting our perspective once again, he takes us on a riveting journey through the universe so we can better comprehend our place in it.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    Diarmuid Jeffreys traces the story of aspirin from the drug's origins in ancient Egypt, through its industrial development at the end of the nineteenth century and its key role in the great flu pandemic of 1918, to its subsequent exploitation by the pharmaceutical conglomerates and the marvelous powers still being discovered today.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    It took a year to accumulate enough so that one could actually see it. Now there is so much that we don't know what to do to get rid of it. We have created a monster.The history of plutonium is as strange as the element itself. When scientists began looking for it, they did so simply in the spirit of inquiry, not certain whether there were still spots to fill on the periodic table. But the discovery of fission made it clear that this still-hypothetical element would be more than just a scientific curiosity?it could be a powerful nuclear weapon.As it turned out, it is good for almost nothing else. Plutonium's nuclear potential put it at the heart of the World War II arms race?the Russians found out about it through espionage, the Germans through independent research, and everybody wanted some. Now, nearly everyone has some?the United States alone has about 47 metric tons?but it has almost no uses besides warmongering. How did the product of scientific curiosity become such a dangerous burden?In his new history of this complex and dangerous element, noted physicist Jeremy Bernstein describes the steps that were taken to transform plutonium from a laboratory novelty into the nuclear weapon that destroyed Nagasaki. This is the first book to weave together the many strands of plutonium's story, explaining not only the science but the people involved.