This critically acclaimed biography offers an unprecedented look at William Masters and Virginia Johnson, their pioneering studies on intimacy, and their lasting impact on the love lives of today's men and women.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    He was bound for a New Jersey dueling ground to settle his bitter dispute with Aaron Burr. Hamilton took just two men with him: his “second” for the duel, and Dr. David Hosack.As historian Victoria Johnson reveals in her groundbreaking biography, Hosack was one of the few points the duelists did agree on. Summoned that morning because of his role as the beloved Hamilton family doctor, he was also a close friend of Burr. A brilliant surgeon and a world-class botanist, Hosack—who until now has been lost in the fog of history—was a pioneering thinker who shaped a young nation.Born in New York City, he was educated in Europe and returned to America inspired by his newfound knowledge. He assembled a plant collection so spectacular and diverse that it amazes botanists today, conducted some of the first pharmaceutical research in the United States, and introduced new surgeries to American. His tireless work championing public health and science earned him national fame and praise from the likes of Thomas Jefferson, James Madison, Alexander von Humboldt, and the Marquis de Lafayette.One goal drove Hosack above all others: to build the Republic’s first botanical garden. Despite innumerable obstacles and near-constant resistance, Hosack triumphed when, by 1810, his Elgin Botanic Garden at last crowned twenty acres of Manhattan farmland. “Where others saw real estate and power, Hosack saw the landscape as a pharmacopoeia able to bring medicine into the modern age” (Eric W. Sanderson, author of Mannahatta). Today what remains of America’s first botanical garden lies in the heart of midtown, buried beneath Rockefeller Center.Whether collecting specimens along the banks of the Hudson River, lecturing before a class of rapt medical students, or breaking the fever of a young Philip Hamilton, David Hosack was an American visionary who has been too long forgotten. Alongside other towering figures of the post-Revolutionary generation, he took the reins of a nation. In unearthing the dramatic story of his life, Johnson offers a lush depiction of the man who gave a new voice to the powers and perils of nature.

    After all, we ourselves are the product of evolution, and we can tackle many of our gravest challenges –– from lethal resurgence of antiobiotic–resistant diseases to the wave of extinctions that looms before us –– with a sound understanding of the science.

    From their diverse fragrances to their nasty deceptions, Russell proves that, where nature is concerned, "wonder is not only our starting point, it can also be our destination." Throughout this botanical journey, she reveals that the science behind these intelligent plants-how they evolved, how they survive, how they heal-is even more awe-inspiring than their fleeting beauty. Russell helps us imagine what a field of snapdragons looks like to a honeybee, and she introduces us to flowers that regulate their own temperature, attract pollinating bats, even smell like a rotting corpse. She also delves into cutting-edge research on everything from flower senses to their healing power. Long used to ease everything from depression to childbirth, flowers are now our main line of defense against childhood leukemia and the deadly Ebola virus. In this poetic rumination, which combines graceful writing with a scientist's clarity, Russell brings together the work of botanists around the globe, and illuminates a world at once familiar and exotic.

     Beginning with her solitary childhood in London, it took years for Melanie Phillips to understand her parents’ emotional frailties and even longer to escape from them. But Phillips inherited her family’s strong Jewish values and a passionate commitment to freedom from oppression. It was this moral foundation that ultimately turned her against the warped and tyrannical attitudes of the Left, requiring her to break away not only from her parents—but also from the people she had seen as her wider political family. Through her poignant story of transformation and separation, we gain insight into the political uproar that has engulfed the West. Britain’s vote to leave the EU, the rise of far-Right political parties in Europe, and the stunning election of US president Donald Trump all involve a revolt against the elites by millions. It is these disdained masses who have been championed by Melanie Phillips in a career as prescient as it has been provocative. Guardian Angel is not only an affecting personal story, but it provides a vital explanation why the West is at a critical crossroads today. “Melanie Phillips has been one of the brave and necessary voices of our time, unafraid to speak the language of moral responsibility in an age of obfuscation and denial. This searing account of her personal journey is compelling testimony to her courage in speaking truth to power.”—Rabbi Lord Jonathan Sacks

    In this selection from The Body, Bill Bryson introduces us to the mysterious, and often devastating, world of disease.

    Like humans, orcas are highly social and depend on their families, but Luna found himself desperately alone. So he tried to make contact with people. He begged for attention at boats and docks. He looked soulfully into people's eyes. He wanted to have his tongue rubbed. When someone whistled at him, he squeaked and whistled back. People fell in love with him, but the government decided that being friendly with Luna was bad for him, and tried to keep him away from humans. Policemen arrested people for rubbing Luna's nose. Fines were levied. Undaunted, Luna refused to give up his search for connection and people went out to meet him, like smugglers carrying friendship through the dark. But does friendship work between species? People who loved Luna couldn't agree on how to help him. Conflict came to Nootka Sound. The government built a huge net. The First Nations' members brought out their canoes. Nothing went as planned, and the ensuing events caught everyone by surprise and challenged the very nature of that special and mysterious bond we humans call friendship. The Lost Whale celebrates the life of a smart, friendly, determined, transcendent being from the sea who appeared among us like a promise out of the blue: that the greatest secrets in life are still to be discovered.

    Life On Air, his autobiography, tells the story of how he has managed to professionalise his schoolboy interests in such a remarkably successful way. Attenborough's Life On Air began in 1950, having taken a degree in Natural Sciences in the University of Cambridge, done National Service in the Navy, got married, done a year as an editor with an educational publisher, had a son and then answered a BBC recruiting ad in the Times. Turned down for BBC Radio, he was offered a traineeship in BBC TV which was pioneering the medium in Britain and he has never looked back. The rest is TV history and you can read Sir David's personal view of it all in his engaging and highly entertaining book. This is no boring story of the rise and rise of a media mogul in the smoke-filled rooms of Ally Pally and Lime Grove. Having served his apprenticeship producing programmes like Animal, Vegetable, Mineral? and Song Hunter with the famous American folk singer and song collector Alan Lomax, he managed to escape from the confines of overlit studios into the natural world. Zoo Quest began in 1954 with an animal collecting trip to Sierra Leone and David Attenborough had found his metier. Since then he has managed to bring the wonders of the natural world into millions of living rooms around the world and to reach general audiences without patronising them, without any spurious antics, silly voices or dumbing down. His animal and plant subjects are the stars, Attenborough is the master of ceremonies who introduces the acts for our wonder and amazement. But his scope extends way beyond the birds and the bees. In the 1960s, it was suggested that he took up an administrative post--"after all, you won't want to be gallivanting around the world when you are 50". Fortunately, he did not abandon gallivanting for admin but went freelance, studied anthropology and helped extend our view of native peoples and sympathies for their life styles. He went on to become responsible for coming up with famous BBC TV series such as Kenneth Clark's incredibly successful Civilisation series, followed by Bronowski's The Ascent of Man. Inevitably, he did become one of the BBC suits but one that wore a camouflage jacket. What is remarkable is that Attenborough has managed to do it for so long without really changing his own style too much. He has not had to because the technology has changed and so he has constantly been able to give new views and insights into the details of life on Earth. Writing pretty much as he speaks, it is easy to hear his voice, dry sense of humour and generosity coming through all the time. Do not expect to read personal details, navel-gazing or malicious gossip--that is not his style. The only personal note comes at the end with the death of his wife in 1997. Over 100 photos associated with the huge range of programmes he has been intimately involved with decorate Life On Air, a fascinating personal story of our times. He says that he knows of "no pleasure deeper than that which comes from contemplating the natural world and trying to understand it"; he certainly manages to convey that in Life On Air. --Douglas Palmer

    Almost a decade earlier, Dr. Sacks had published his masterpiece Awakenings but the book had hardly been an immediate success, and the rumpled clinician was still largely unknown. Over the ensuing four years, the two men worked closely together until Sacks asked Weschler to abandon the profile, a request to which Weschler acceded. The two remained close friends, however, across the next thirty years and then, just as Sacks was dying, he urged Weschler to take up the project once again. This book is the result of that entreaty.Weschler sets Sacks's brilliant table talk and extravagant personality in vivid relief. We see Sacks rowing and ranting and caring deeply; composing the essays that would form The Man Who Mistook His Wife for a Hat ; recalling his turbulent drug-fueled younger days; helping his patients and exhausting his friends; and waging intellectual war against a medical and scientific establishment that failed to address his greatest concern: the spontaneous specificity of the individual human soul. And all the while he is pouring out a stream of glorious, ribald, hilarious, and often profound conversation that establishes him as one of the great talkers of the age.

    He was sleek and prosperous, with a dainty goatee. Though he smiled reassuringly, the poet noticed that he kept a safe distance. In a soothing, urbane voice, the physician explained the treatment: stewed prunes to evacuate the bowels; succulent meats to ease digestion; cinnabar and the sweating tub to cleanse the disease from the skin. The doctor warned of minor side effects: uncontrolled drooling, fetid breath, bloody gums, shakes and palsies. Yet desperate diseases called for desperate remedies, of course.Were Shakespeare's shaky handwriting, his obsession with venereal disease, and his premature retirement connected? Did John Milton go blind from his propaganda work for the Puritan dictator Oliver Cromwell, as he believed, or did he have a rare and devastating complication of a very common eye problem? Did Jonathan Swift's preoccupation with sex and filth result from a neurological condition that might also explain his late-life surge in creativity? What Victorian plague wiped out the entire Brontë family? What was the cause of Nathaniel Hawthorne's sudden demise? Were Herman Melville's disabling attacks of eye and back pain the product of "nervous affections," as his family and physicians believed, or did he actually have a malady that was unknown to medical science until well after his death? Was Jack London a suicide, or was his death the product of a series of self-induced medical misadventures? Why did W. B. Yeats's doctors dose him with toxic amounts of arsenic? Did James Joyce need several horrific eye operations because of a strange autoimmune disease acquired from a Dublin streetwalker? Did writing Nineteen Eighty-Four actually kill George Orwell? The Bard meets House, M.D. in this fascinating untold story of the impact of disease on the lives and works of some the finest writers in the English language. In Shakespeare's Tremor and Orwell's Cough, John Ross cheerfully debunks old biographical myths and suggests fresh diagnoses for these writers' real-life medical mysteries. The author takes us way back, when leeches were used for bleeding and cupping was a common method of cure, to a time before vaccinations, sterilized scalpels, or real drug regimens. With a healthy dose of gross descriptions and a deep love for the literary output of these ten greats, Ross is the doctor these writers should have had in their time of need.

    King (William and Mary University) delves into the story of how, why, where, and when we became human. These lectures will help you understand the forces that have shaped, and continue to shape, our species. "An evolutionary perspective on human behavior," notes Dr. King, "results in more than just knowledge about dates and sites when and where specific evolutionary milestones likely occurred." "It is also a window on the past and future of our species. An entirely new way of thinking comes into focus when we consider the human species within an evolutionary perspective."A Century of ScholarshipWhile covering these subjects in this 24-lecture series, Dr. King synthesizes the best that more than a century of scientific scholarship has to offer across a variety of disciplines. Biological anthropologists study primate anatomy and behavior both to understand evolution and to learn more about our common ancestor. Biological anthropologists are joined by molecular anthropologists to better understand hominids by studying fossils, ancient skeletal remains, and lifestyle information such as cave art and stone tools. Case Studies that Clarify Evolution and Its Power Dr. King begins by explaining key mechanisms through which evolution functions, citing famous and definitive case studies that demonstrate these forces. In one such landmark study, for example, biologists Peter and Rosemary Grant returned to the Galapagos Islands more than 100 years after Darwin's first voyage to conduct research on island finches. In 1977, a drought-induced scarcity of soft, edible seeds brought forth in the very next generation a population of finches with larger, stronger beaks capable of crushing larger, tougher seeds. Extraordinarily, in 1985, heavy rains produced a surplus of softer seeds, and natural selection produced a succeeding generation of the smaller-beaked variety. Evolution had occurred in two different directions within a decade. This "natural selection" is the theoretical tool of evolution, which helps us make sense of these facts. Why Evolution Remains Important to Us Today Perhaps the greatest measure of this theory's power is its relevance to our lives today. - Did you know that the gene which causes sickle cell anemia must be inherited from both parents to cause the disease but the disease does not occur when only a single gene is inherited? - Or that the single gene, in fact, affords protection from malaria? Or that race, a category so securely ingrained in our consciousness, is practically meaningless in biological terms? - Or how to evaluate the claim that a gene can be responsible for a certain personality trait? A Glimpse Into Our Selected Primate Heritage With an understanding of the basic mechanisms of evolutionary change in hand, the course looks at how our ancient primate ancestors adapted. Consider the anatomical features we share with monkeys, great apes, and other primates. Our large brains, grasping hands, and forward-facing eyes allowing us to perceive depth are critical to the way we function in the world. Yet the fossil record tells us that some 70 million years ago these distinctive primate features did not exist. What caused the first primates to emerge from existing mammalian populations? One proposed solution was that the appearance of insects living in the lower canopies of trees offered a plentiful food resource to those species adapted to procure it. Could depth perception and grasping ability have provided an advantage here, and hence been naturally selected? This is the function of biological anthropology: confronting the facts, then suggesting and testing possibilities. A Course as Much About the Present as the PastWith so much of evolutionary history taken up with the past, the insights gained in these lectures may tempt you to add questions of your own: - Is human evolution still a force in today's world? Hasn't our modern, mobile culture rendered evolution irrelevant? - In fact, human evolution is a stronger force than ever, interacting with human culture in complex ways. Issues such as obesity, AIDS, and genetics are all discussed. And you may well find these lectures opening your eyes to the extraordinary ways in which the biological power of natural selection is still at work in the world today. Course Lecture Titles1. What is Biological Anthropology? 2. How Evolution Works 3. The Debate Over Evolution 4. Matter Arising—New Species 5. Prosimians, Monkeys, and Apes 6. Monkey and Ape Social Behavior 7. The Mind of the Great Ape 8. Models for Human Ancestors? 9. Introducing the Hominids 10. Lucy and Company 11. Stones and Bones 12. Out of Africa 13. Who Were the Neandertals? 14. Did Hunting Make Us Human? 15. The Prehistory of Gender 16. Modern Human Anatomy and Behavior 17. On the Origins of Homo sapiens 18. Language 19. Do Human Races Exist? 20. Modern Human Variation 21. Body Fat, Diet, and Obesity 22. The Body and Mind Evolving 23. Tyranny of the Gene? 24. Evolution and Our Future

    He had a talent for drawing and an interest in birds, and he would spend the next thirty-five years traveling to the remotest regions of his new country–often alone and on foot–to render his avian subjects on paper. The works of art he created gave the world its idea of America. They gave America its idea of itself. Here Richard Rhodes vividly depicts Audubon’s life and career: his epic wanderings; his quest to portray birds in a lifelike way; his long, anguished separations from his adored wife; his ambivalent witness to the vanishing of the wilderness. John James Audubon: The Making of an American is a magnificent achievement.

    In the aftermath of that six-year old's abduction and slaying in 1981, everything about the nation's regard and response to missing children changed.The shock of the crime and the inability of law enforcement to find Adam's killer put an end to innocence, and altered our very perception of childhood itself - gone forever are the days when young children burst out the doors of American homes with a casual promise to be home by dark. And, due in large part to the efforts of Adam's parents, John and Reve Walsh, the entire mechanism of law enforcement has transformed itself in an effort to protect our children.Before Adam went missing, there were no children's faces on milk cartons and billboards, no Amber Alerts, no national Center for Missing and Abused Children, no national databases for crimes against children, no registration of pedophiles - in fact, it was easier to mobilize the FBI to search for a stolen car or missing horse than for a kidnapped child. Such facts may be sad testimony to the weariness of a modern world, but there is also an uplifting aspect to Adam's story - the 27 years of undaunted effort by decorated Miami Beach Homicide Detective, Joe Matthews, to track down Adam's killer and bring justice to bear at long last.Bringing Adam Home tells the story - the good, the bad, and the ugly - of what it took for one cop to accomplish what an entire system of law enforcement could not. Matthews' achievement is a stirring one, reminding us that such concepts as hard work, dedication, and love, survive, and that goodness can prevail.

    That rook, named Chicken, has lived with the family ever since - along with a talking magpie named Spike and a crow named Ziki. A blend of memoir and natural history, this book brings Chicken and the others vividly to life.