At first unable to run 400 metres without stopping, Laura has now completed five marathons, the most recent in under four hours. Along the way, Laura learns countless lessons about running, most of them the hard way. But most importantly this self-confessed couch potato learns to love running. As well as offering inspiration and motivation to get out there and run, her book offers tips on how to make running easier and more enjoyable. Offering practical information on buying the right kit, choosing the best race and what to do on race day, it also tackles the important running questions you might be embarrassed to ask – like when will it get easier? And what happens if I need the toilet?

    And I am at the hospital. A coming-of-age memoir for modern times, Bleeder is the incredibly compelling tale of author Shelby Smoak. A hemophiliac, Smoak discovered he had been infected with HIV during a blood transfusion at the start of his college career. This devastating and destabilizing news led Smoak to see his world from an entirely new perspective, one in which life-threatening illness was perpetually just around the corner. Set in the 1990s along the North Carolina coast, Bleeder traces Smoak’s quest for love in a world that feels increasingly dangerous, and despite a future that feels increasingly uncertain. From the bedroom to the operating room, and from one hospital to the next, Smoak seeks out hope and better health. Winner of a PEN American Center award for writers living with HIV, Smoak, whose work has appeared in numerous journals and magazines, constructs this unforgettable story of life and love against insurmountable difficulties in breathtaking, tightly drawn prose.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    You’ll smile at some of Andy’s real patient encounters, while others will cause you to wipe a tear. Using official NHS documentation recorded at the time to give precise details of each incident, Andy has held firm to the real-life accounts, even in keeping the dialogue as close as his memory allows to what was really said at the time. It’s as if you’re there next to him, struggling with the effects of adrenaline and fighting to save life. This is a rare work of medical non-fiction delivered in a way that is factual, informative, but at the same time naturally entertaining and moving, written with candour and humour. And if you have ever thought what it takes to become a paramedic – or any other of the specialist vocations - and that you could never achieve it yourself, Andy’s inspiring story of how he went from postman to frontline healthcare professional, fulfilling his dream, will make you think again that anything is possible if you have the desire. Andy says there are no heroics in the book and that he simply did his job, but we are sure The Dark Side will leave you convinced there are true heroes on our streets right here, right now. Saving lives every day, every night and often against all the odds. It might even change your whole perspective on life.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Welcome to laughing until it hurts while covered in bodily fluids. Welcome to simple math at very high stakes. Welcome to an incredibly inappropriate sense of humor. Welcome to serving people on the most stressful days of their lives. Welcome to putting your hands in places you never imagined they'd be. Welcome to your front row seat to the ballad of life and death. That's not the welcome that this nurse was looking for, but that's the one he got. Irreverent and audacious, this brutally honest memoir covers what it’s like to come of age in an American Hospital. Welcome to a rollicking peak behind the curtain to what medical providers, and the health care system, are truly like.

    He was twelve years old and he had a guitar. He would go around telling everybody that he was going to be a rock-and-roll star. I was eleven and I believed him.”SO BEGINS THIS HONEST, FUNNY, AND DEEPLY AFFECTIONATE MEMOIR OF A FRIENDSHIP THAT HAS SPANNED FIVE DECADES OF WILD ADVENTURES, SOUL SEARCHING CONVERSATION, MUSICAL MILESTONES, AND ENDURING COMRADERY.Louie and Bob after the Rolling Thunder Night of the Hurricane Benefit Concert at Madison Square Garden, December 8th, 1975.Louie and Bob after the Rolling Thunder Night of the Hurricane Benefit Concert at Madison Square Garden, December 8th, 1975.As Bobby Zimmerman became Bob Dylan and Louie Kemp built a successful international business, their lives diverged but their friendship held fast. No matter how much time passed between one adventure and the next, the two “boys from the North Country” picked up where they left off and shared experiences that will surprise and delight Dylan fans and anybody who loves a rollicking-good rock-and-roll memoir. From little Bobby’s very first public appearance (on a roof at Herzl Camp) through his formative years in Minnesota and New York and his rise to global superstardom, Louie Kemp was by his side—a trusted ally and confidant as Bob figured out how to share his gifts without compromising who he was. Louie produced Bob’s groundbreaking Rolling Thunder Revue—described in riveting detail here—and traveled with him in the rarefied world of the rock star, but he also shared quiet moments and intimate experiences. When Louie got married, Bob was his best man; when Bob questioned his Jewish faith, Louie brought him back to the fold. And that is just a small sample of the never-before-told, up-close-and-personal stories in this eye-opening book. Ever wonder what it might be like to attend a Passover Seder with Bob Dylan and Marlon Brando? Or go on a Mexican vacation with Bob Dylan, Dennis Hopper, and Harry Dean Stanton? Or get into a public food fight with Joan Baez? Read on.Louie’s own words best describe the relationship at the heart of Dylan & Me: “We have always had open minds, taken risks, helped the underdog. We have laughed at the same jokes and confided our deepest thoughts and fears. We have never needed anything from each other but have always been there for each other.” What better definition of friendship could anybody want?

    Because of his studies of the Eskimos, his discoveries of land, the application of new ideas and new methods of exploration, Stefansson was considered the foremost polar explorer of his day, and one of the few great explorers of all time. During a period of three or four years Mr. Stefansson has produced a creditable list of books about the Arctic. In some respects his service in publishing the results of his Northern studies has differed from that of earlier explorers. He has challenged our preconceptions about the Arctic. “Hunters of the Great North” gives details of Northern life such as have doubtless come within the experience of all Arctic explorers, but which are new to the average American reader. In short, it is an elementary text-book of the Arctic. Stefansson lived among the Eskimos of the Mackenzie River, studying their language and adopting their mode of life, and spending ten winters and thirteen summers in the polar regions. Among Stefannson's most famous discovery was that of a race of blond Eskimo on Coronation Gulf. Stefansson writes: "In the present book I have tried by means of diaries and memory to go back to the vivid impressions of my first year among the Eskimos for the story of what I saw and heard." In describing his confrontation with a polar bear, Stefansson writes: “I heard behind me a noise like the spitting of a cat or the hiss of a goose. I looked back and saw, about twenty feet away and almost above me, a polar bear. I had overestimated the bear's distance from shore, and had passed the spot where he lay. From his eye and attitude, as well as the story his trail told afterward there was no doubting his intentions: the hiss was merely his way of saying, "Watch me do it!" Or at least that is how I interpreted it; possibly the motive was chivalry, and the hiss was his way of saying Garde!” Contents I. PREPARATIONS FOR A LIFEWORK OF EXPLORATION II. DOWN THE MACKENZIE RIVER THROUGH 2000 MILES OF INDIAN COUNTRY III. FIRST IMPRESSIONS OF THE ESKIMOS IV. CAPTAIN KLINKENBERG—SEA WOLF AND DISCOVERER V. THE WHALING FLEET SAILS AWAY VI. LEARNING TO LIVE AS AN ESKIMO—ON A DIET OF FISH WITHOUT SALT VII. HOW AN ESKIMO SAILED THROUGH THE STORM VIII. AN AUTUMN JOURNEY THROUGH ARCTIC MOUNTAINS IX. THE SUN GOES AWAY FOR THE WINTER X. LOST IN THE MACKENZIE DELTA XI. AN ARCTIC CHRISTMAS WITH AN ENGLISH COUNTRY GENTLEMAN XII. THE LIFE AT TUKTUYAKTOK XIII. LEARNING TO BUILD A SNOWHOUSE AND TO BE COMFORTABLE IN ONE XIV. TRAVELS AFTER THE SUN CAME BACK XV. WE GO IN SEARCH OF OUR OWN EXPEDITION XVI. A SPRING JOURNEY IN AN ESKIMO SKIN BOAT XVII. A RACE OVER THE ARCTIC MOUNTAINS IN SUMMER XVIII. ON A RAFT DOWN THE PORCUPINE RIVER SHORT STORIES OF ADVENTURE I. HOW I LEARNED TO HUNT CARIBOU II. HOW I LEARNED TO HUNT SEALS III. HOW WE HUNT POLAR BEARS

    This is a gripping medical narrative that brings readers into the complex world of newborn intensive care, where brilliant but imperfect doctors do all they can to coax life into their tiny, injured patients.

    No money. No passport. No identity.Taken to a mental hospital by the police, MacLean then started to hallucinate so severely he had to be tied down. Soon he could remember song lyrics, but not his family, his friends, or the woman he was told he loved. All of these symptoms, it turned out, were the result of the commonly prescribed malarial medication he had been taking. Upon his return to the States, he struggled to piece together the fragments of his former life in a harrowing, absurd, and unforgettable journey back to himself.The Answer to the Riddle Is Me, drawn from David MacLean’s award-winning This American Life essay, is a deeply felt, closely researched, and intensely personal book. It asks every reader to confront the essential questions of our age: In our geographically and chemically fluid world, what makes me who I am? And how much can be stripped away before I become someone else entirely?

    January 30, 1969 was one of those moments. There are those who were on the periphery of the event that day and heard what was going on; but as one of the few remaining insiders who accompanied the Beatles up onto the cold windswept roof of the Apple building, Ken Mansfield had a front row seat to the full sensory experience of the moment and witnessed what turned out to be beginning of the end. Ken shares in The Roof: The Beatles Final Concert, the sense that something special was taking place before his eyes that would live on forever in the hearts and souls of millions. As the US manager of Apple, Ken Mansfield was on the scene in the days, weeks, and months leading up to this monumental event. He shares his insights into the factors that brought them up onto that roof and why one of the greatest bands of all time left it all on that stage. Join Ken as he reflects on the relationships he built with the Fab Four and the Apple corps and what each player meant to this symphony of music history.

    Odder still, she reveals that she’s suffering from a persistent memory problem. Routinely, she “loses” parts of her day, finding herself in places she doesn’t remember going to or being told about conversations she doesn’t remember having. Her problems are so pervasive that she often feels like an impersonator in her own life; she doesn’t recognize the people who call themselves her friends, and she can’t even remember being intimate with her own husband. Baer recognizes that Karen is on the verge of suicide and, while trying various medications to keep her alive, attempts to discover the root cause of her strange complaints. It’s the work of months, and then years, to gain Karen’s trust and learn the true extent of the trauma buried in her past. What she eventually reveals is nearly beyond belief, a narrative of a childhood spent grappling with unimaginable horror. How has Karen survived with even a tenuous grasp on sanity?Then Baer receives an envelope in the mail. It’s marked with Karen’s return address but contains a letter from a little girl who writes that she’s seven years old and lives inside of Karen. Soon Baer receives letters from others claiming to be parts of Karen. Under hypnosis, these alternate Karen personalities reveal themselves in shocking variety and with undeniable traits—both physical and psychological. One “alter” is a young boy filled with frightening aggression; another an adult male who considers himself Karen’s protector; and a third a sassy flirt who seeks dominance over the others. It’s only by compartmentalizing her pain, guilt, and fear in this fashion—by “switching time” with alternate selves as the situation warrants—that Karen has been able to function since childhood.Realizing that his patient represents an extreme case of multiple personality disorder, Baer faces the daunting task of creating a therapy that will make Karen whole again. Somehow, in fact, he must gain the trust of each of Karen’s seventeen “alters” and convince them of the necessity of their own annihilation.As powerful as Sybil or The Three Faces of Eve, Switching Time is the first complete account of such therapy to be told from the perspective of the treating physician, a stunningly devoted healer who worked selflessly for decades so that Karen could one day live as a single human being.From the Hardcover edition.

    Two leading cardiologists draw on their collective fifty years of clinical cardiology research to show you how to combine the benefits of modern medicine, over-the-counter vitamins and supplements, and simple lifestyle changes to have a healthy heart.

    Bennet Omalu, the pathologist who made one of the most significant medical discoveries of the twenty-first century, a discovery that challenges the existence of America’s favorite sport and puts Omalu in the crosshairs of football’s most powerful corporation: the NFL. Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria. The body on the slab in front of him belonged to a fifty-year-old named Mike Webster, aka “Iron Mike,” a Hall of Fame center for the Pittsburgh Steelers, one of the greatest ever to play the game. After retiring in 1990, Webster had suffered a dizzyingly steep decline. Toward the end of his life, he was living out of his van, tasering himself to relieve his chronic pain, and fixing his rotting teeth with Super Glue. How did this happen?, Omalu asked himself. How did a young man like Mike Webster end up like this? The search for answers would change Omalu’s life forever and put him in the crosshairs of one of the most powerful corporations in America: the National Football League. What Omalu discovered in Webster’s brain—proof that Iron Mike’s mental deterioration was no accident but a disease caused by blows to the head that could affect everyone playing the game—was the one truth the NFL wanted to ignore.   Taut, gripping, and gorgeously told, Concussion is the stirring story of one unlikely man’s decision to stand up to a multibillion-dollar colossus, and to tell the world the truth.  Advance praise for Concussion “A gripping medical mystery and a dazzling portrait of the young scientist no one wanted to listen to . . . a fabulous, essential read.”—Rebecca Skloot, author of The Immortal Life of Henrietta Lacks“The story of Dr. Bennet Omalu’s battle against the NFL is classic David and Goliath stuff, and Jeanne Marie Laskas—one of my favorite writers on earth—makes it as exciting as any great courtroom or gridiron drama. A riveting, powerful human tale—and a master class on how to tell a story.”—Charles Duhigg, author of The Power of Habit   “Bennet Omalu forced football to reckon with head trauma. The NFL doesn’t want you to hear his story, but Jeanne Marie Laskas makes it unforgettable. This book is gripping, eye-opening, and full of heart.”—Emily Bazelon, author of Sticks and Stones

    She was ambitious and worked hard; she had just bought an apartment; she was falling in love. But then she started to develop worrying symptoms: her face felt like it was burning whenever she was in front of the computer. Soon this progressed to an intolerance of fluorescent light, then of sunlight itself. The reaction soon spread to her entire body. Now, when her symptoms are at their worst, she must spend months on end in a blacked-out room, losing herself in audio books and elaborate word games in an attempt to ward off despair. It was during this period she began to write this book.