Over the years, she has made history with a legendary talk show - the highest-rated program of its kind, launched her own television network, become the nation's only African-American billionaire, and been awarded both an honorary degree by Harvard University and the Presidential Medal of Freedom. From all her experiences, she has gleaned life lessons—which, for fourteen years, she's shared in O, The Oprah Magazine's widely popular "What I Know For Sure" column, a monthly source of inspiration and revelation.Now, for the first time, these thoughtful gems have been revised, updated, and collected in What I Know For Sure, a beautiful cloth bound book with a ribbon marker, packed with insight and revelation from Oprah Winfrey. Organized by theme—joy, resilience, connection, gratitude, possibility, awe, clarity, and power—these essays offer a rare, powerful and intimate glimpse into the heart and mind of one of the world's most extraordinary women—while providing readers a guide to becoming their best selves. Candid, moving, exhilarating, uplifting, and frequently humorous, the words Oprah shares in What I Know For Sure shimmer with the sort of truth that readers will turn to again and again.

     “A pleasure. Ellie Kemper is the kind of stable, intelligent, funny, healthy woman that usually only exists in yogurt commercials. But she’s real and she’s all ours!” —Tina Fey “Ellie is a hilarious and talented writer, although we’ll never know how much of this book the squirrel wrote.”—Mindy KalingMeet Ellie, the best-intentioned redhead next door. You’ll laugh right alongside her as she shares tales of her childhood in St. Louis, whether directing and also starring in her family holiday pageant, washing her dad’s car with a Brillo pad, failing to become friends with a plump squirrel in her backyard, eating her feelings while watching PG-13 movies, or becoming a “sports monster” who ends up warming the bench of her Division 1 field hockey team in college. You’ll learn how she found her comedic calling in the world of improv, became a wife, mother and New Yorker, and landed the role of a bridesmaid (while simultaneously being a bridesmaid) in Bridesmaids. You’ll get to know and love the comic, upbeat, perpetually polite actress playing Erin Hannon on The Office, and the exuberant, pink-pants-wearing star of Unbreakable Kimmy Schmidt. If you’ve ever been curious about what happens behind the scenes of your favorite shows, what it really takes to be a soul cycle “warrior,” how to recover if you accidentally fall on Doris Kearns Goodwin or tell Tina Fey on meeting her for the first time that she has “great hair—really strong and thick,” this is your chance to find out. But it’s also a laugh-out-loud primer on how to keep a positive outlook in a world gone mad and how not to give up on your dreams. Ellie “dives fully into each role—as actor, comedian, writer, and also wife and new mom—with an electric dedication, by which one learns to reframe the picture, and if not exactly become a glass-half-full sort of person, at least become able to appreciate them” (Vogue.com).

    She just knew she felt her best when she was empty, "like a straw", as she says "something you could blow through."For almost thirty years, Susan Burton has hidden her obsession with food and the secret life of compulsive eating and starving that dominated her adolescence. This is the relentlessly honest, fiercely intelligent story of living with both anorexia and binge-eating disorder, moving past her shame, and learning to tell her secret.When Burton was thirteen, her stable life in suburban Michigan was turned upside down by her parents' abrupt divorce, and she moved to Colorado with her mother and sister. She seized on this move west as an adventure and an opportunity to reinvent herself from middle-school nerd to popular teenage girl. But she hadn't escaped unscathed, and in the fallout from her parents' breakup, an inherited fixation on thinness went from "peculiarity to pathology." She entered into a painful cycle of anorexia and binge eating that formed a subterranean layer to her sunny life. She went from success to success--she went to Yale, scored a dream job at a magazine right out of college, and married her college boyfriend. But in college the compulsive eating got worse--she'd binge, swear it would be the last time, and then, hours later, do it again--and after she graduated she descended into anorexia, her attempt to "quit food."Binge eating is more prevalent than anorexia or bulimia, but there is less research and little storytelling to help us understand it. In tart, soulful prose Susan Burton strikes a blow for the importance of this kind of story; brings to life an indelible cast of characters; and tells an exhilarating story of longing, compulsion and hard-earned self-revelation.

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    They ate braised leeks. They played by themselves while their parents sipped coffee. And yet French kids were still boisterous, curious, and creative. Why? How?            With a notebook stashed in her diaper bag, Druckerman set out to investigate—and wound up sparking a national debate on parenting. Researched over three years and written in her warm, funny voice, Bringing Up Bébé is deeply wise, charmingly told, and destined to become a classic resource for American parents.

    They fell in love at eighteen, married at twenty-four, and were living their dream life in San Francisco. When Giulia was twenty-seven, she suffered a terrifying and unexpected psychotic break that landed her in the psych ward for nearly a month. One day she was vibrant and well-adjusted; the next she was delusional and suicidal, convinced that her loved ones were not safe.Eventually, Giulia fully recovered, and the couple had a son. But, soon after Jonas was born, Giulia had another breakdown, and then a third a few years after that. Pushed to the edge of the abyss, everything the couple had once taken for granted was upended.A story of the fragility of the mind, and the tenacity of the human spirit, My Lovely Wife in the Psych Ward is, above all, a love story that raises profound questions: How do we care for the people we love? What and who do we live for? Breathtaking in its candor, radiant with compassion, and written with dazzling lyricism, Lukach’s is an intensely personal odyssey through the harrowing years of his wife’s mental illness, anchored by an abiding devotion to family that will affirm readers’ faith in the power of love.

    But it wasn’t long before they noticed a marked difference between Jonas and his brother, Wyatt. Jonas preferred sports and trucks and many of the things little boys were “supposed” to like; but Wyatt liked princess dolls and dress-up and playing Little Mermaid. By the time the twins were toddlers, confusion over Wyatt’s insistence that he was female began to tear the family apart. In the years that followed, the Maineses came to question their long-held views on gender and identity, to accept and embrace Wyatt’s transition to Nicole, and to undergo an emotionally wrenching transformation of their own that would change all their lives forever.Becoming Nicole chronicles a journey that could have destroyed a family but instead brought it closer together. It’s the story of a mother whose instincts told her that her child needed love and acceptance, not ostracism and disapproval; of a Republican, Air Force veteran father who overcame his deepest fears to become a vocal advocate for trans rights; of a loving brother who bravely stuck up for his twin sister; and of a town forced to confront its prejudices, a school compelled to rewrite its rules, and a courageous community of transgender activists determined to make their voices heard. Ultimately, Becoming Nicole is the story of an extraordinary girl who fought for the right to be herself.Granted wide-ranging access to personal diaries, home videos, clinical journals, legal documents, medical records, and the Maineses themselves, Amy Ellis Nutt spent almost four years reporting this immersive account of an American family confronting an issue that is at the center of today’s cultural debate. Becoming Nicole will resonate with anyone who’s ever raised a child, felt at odds with society’s conventions and norms, or had to embrace life when it plays out unexpectedly. It’s a story of standing up for your beliefs and yourself—and it will inspire all of us to do the same.

    She has managed to achieve this in spite of being diagnosed as schizophrenic and given a "grave" prognosis—and suffering the effects of her illness throughout her life.Saks was only eight, and living an otherwise idyllic childhood in sunny 1960s Miami, when her first symptoms appeared in the form of obsessions and night terrors. But it was not until she reached Oxford University as a Marshall Scholar that her first full-blown episode, complete with voices in her head and terrifying suicidal fantasies, forced her into a psychiatric hospital.Saks would later attend Yale Law School where one night, during her first term, she had a breakdown that left her singing on the roof of the law school library at midnight. She was taken to the emergency room, force-fed antipsychotic medication, and tied hand-and-foot to the cold metal of a hospital bed. She spent the next five months in a psychiatric ward.So began Saks's long war with her own internal demons and the equally powerful forces of stigma. Today she is a chaired professor of law who researches and writes about the rights of the mentally ill. She is married to a wonderful man.In The Center Cannot Hold, Elyn Saks discusses frankly and movingly the paranoia, the inability to tell imaginary fears from real ones, and the voices in her head insisting she do terrible things, as well as the many obstacles she overcame to become the woman she is today. It is destined to become a classic in the genre.

    She takes us by her side down hospital corridors to visit the wards and meet her unforgettable patients.In the neonatal unit, premature babies fight for their lives, hovering at the very edge of survival, like tiny Emmanuel, wrapped up in a sandwich bag. On the cancer wards, the nurses administer chemotherapy and, long after the medicine stops working, something more important--which Watson learns to recognize when her own father is dying of cancer. In the pediatric intensive care unit, the nurses wash the hair of a little girl to remove the smell of smoke from the house fire. The emergency room is overcrowded as ever, with waves of alcohol and drug addicted patients as well as patients like Betty, a widow suffering chest pain, frail and alone. And the stories of the geriatric ward--Gladys and older patients like her--show the plight of the most vulnerable members of our society.

    Fox.The entire world knows Michael J. Fox as Marty McFly, the teenage sidekick of Doc Brown in Back to the Future; as Alex P. Keaton in Family Ties; as Mike Flaherty in Spin City; and through numerous other movie roles and guest appearances on shows such as The Good Wife and Curb Your Enthusiasm. Diagnosed at age 29, Michael is equally engaged in Parkinson’s advocacy work, raising global awareness of the disease and helping find a cure through The Michael J. Fox Foundation for Parkinson’s Research, the world’s leading non-profit funder of PD science. His two previous bestselling memoirs, Lucky Man and Always Looking Up, dealt with how he came to terms with the illness, all the while exhibiting his iconic optimism. His new memoir reassesses this outlook, as events in the past decade presented additional challenges.In No Time Like the Future: An Optimist Considers Mortality, Michael shares personal stories and observations about illness and health, aging, the strength of family and friends, and how our perceptions about time affect the way we approach mortality. Thoughtful and moving, but with Fox’s trademark sense of humor, his book provides a vehicle for reflection about our lives, our loves, and our losses.Running through the narrative is the drama of the medical madness Fox recently experienced, that included his daily negotiations with the Parkinson’s disease he’s had since 1991, and a spinal cord issue that necessitated immediate surgery. His challenge to learn how to walk again, only to suffer a devastating fall, nearly caused him to ditch his trademark optimism and “get out of the lemonade business altogether.”

    Very, very real. Actor, writer and comedian, Celeste Barber is one very funny woman - not to mention a global social media comedy phenomenon. Amassing over 3 million followers in only 18 months with her hilarious #challengeaccepted pics, she has been dubbed 'Australian Comedy Queen' by ABC Online; voted The Funniest Lady on Instagram; gone on sold-out comedy tours of US and UK; and won herself fans ranging from Tom Ford and Ruby Rose, to Amy Schumer and Dawn French. In the tradition of Tina Fey's Bossypants, Celeste's memoir is part memoir, part comedy routine, part advice manual. Calling out our ridiculous celebrity Instagram culture and the obsession we all seem to have with how we look, Celeste reveals all, including her thoughts on keeping it real and feeling good (instead of worrying about looking good); the secrets to love, friendship, family and marriage (#hothusband); how to deal with life's many challenges, like, well, motherhood, among other things; and how to stay nice in Spanx. Celeste is real, hilarious and the world can't get enough of her.

    A recent recipient of National Book Critics Circle Ivan Sandrof Lifetime Achievement Award, Oates, whose novels (Blonde, The Gravedigger’s Daughter, Little Bird of Heaven, etc.) rank among the very finest in contemporary American fiction, offers an achingly personal story of love and loss. A Widow’s Story is a literary memoir on a par with The Year of Magical Thinking by Joan Didion and Calvin Trillin’s About Alice.

    The book soared to the top of bestseller lists internationally, igniting global conversations about women and ambition. Sandberg packed theatres, dominated opinion pages, appeared on every major television show and on the cover of Time magazine, and sparked ferocious debate about women and leadership. Ask most women whether they have the right to equality at work and the answer will be a resounding yes, but ask the same women whether they'd feel confident asking for a raise, a promotion, or equal pay, and some reticence creeps in. The statistics, although an improvement on previous decades, are certainly not in women's favour – of 197 heads of state, only twenty-two are women. Women hold just 20 percent of seats in parliaments globally, and in the world of big business, a meagre eighteen of the Fortune 500 CEOs are women. In Lean In, Sheryl Sandberg – Facebook COO and one of Fortune magazine's Most Powerful Women in Business – draws on her own experience of working in some of the world's most successful businesses and looks at what women can do to help themselves, and make the small changes in their life that can effect change on a more universal scale.

    I laughed. I cried. I got another cat.”  —Lily Tomlin “Paula Poundstone is the funniest human being I have ever known.” —Peter Sagal, host of Wait Wait . . . Don’t Tell Me! and author of The Book of Vice “Is there a secret to happiness?” asks comedian Paula Poundstone. "I don’t know how or why anyone would keep it a secret. It seems rather cruel, really . . . Where could  it be? Is it deceptively simple? Does it melt at a certain temperature? Can you buy it? Must you suffer for it before or after?” In her wildly and wisely observed book, the comedy legend takes on that most inalienable of rights—the pursuit of happiness. Offering herself up as a human guinea pig in a series of thoroughly unscientific experiments, Poundstone tries out a different get-happy hypothesis in each chapter of her data-driven search. She gets in shape with taekwondo. She drives fast behind the wheel of a Lamborghini. She communes with nature while camping with her daughter, and commits to getting her house organized (twice!). Swing dancing? Meditation? Volunteering? Does any of it bring her happiness? You may be laughing too hard to care.  The Totally Unscientific Study of the Search for Human Happiness is both a story of jumping into new experiences with both feet and a surprisingly poignant tale of a single working mother of three children (not to mention dozens of cats, a dog, a bearded dragon lizard, a lop-eared bunny, and one ant left from her ant farm) who is just trying to keep smiling while living a busy life. The queen of the skepticism-fueled rant, Paula Poundstone stands alone in her talent for bursting bubbles and slaying sacred cows. Like George Carlin, Steve Martin, and David Sedaris, she is a master of her craft, and her comedic brilliance is served up in abundance in this book. As author and humorist Roy Blount Jr. notes, “Paula Poundstone deserves to be happy. Nobody deserves to be this funny.”

    Inspired by Victorian household manuals, Notaro chronicles her chronic misfortune in the domestic arts, including cooking, cleaning, and putting on Spanx while sweaty (which should technically qualify as an Olympic sport). Housebroken is a rollicking new collection of essays showcasing her irreverent wit and inability to feel shame. From defying nature in the quest to making her own Twinkies, to begging her new neighbors not to become urban livestock keepers, to teaching her eight-year-old nephew about hobos, Notaro recounts her best efforts—and hilarious failures—in keeping a household inches away from being condemned. After all, home wasn’t built in a day.