Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation? In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients—a Biotech Social Contract. Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including: Why doesn’t insurance make drugs affordable? How can we prevent price-jacking of older drugs? Why are drugs more expensive in America than elsewhere? How can we guarantee that all medicines eventually go generic so they are only temporarily expensive? What systemic failures led to the opioid crisis, and how can we prevent the next one? The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.

    Worldreader addresses that problem using e-reader technology. Worldreader works with textbook publishers across the developing world to offer a range of digital textbooks to schools as part of their wider goal to promote literacy by bringing books to all.

    The project's goal is to show that the ability to control the body's temperature is not a genetic defect in Wim, but an ability that can be adopted by everyone. For many generations, we have been taught to fear the cold:"Don't forget your jacket! You don't want hypothermia, do you?""Put your gloves on before you get frostbite!"Of course, these are consequences of extreme cold exposure, but with the proper understanding, anyone can learn to use the cold as a natural teacher.You may have seen Wim Hof on television running barefoot through the snow or swimming in ice-cold waters. While performing those incredible feats, Wim remained completely warm and comfortable the entire time! Wim is the epitome of what can happen if someone uses the cold to train the body. Like any new tool, you must understand how it works before you can use it efficiently. This pertains to the cold as well. You may be wondering, "How can you prove that anyone can learn this ability?Well, as of Fall 2009, Justin Rosales had no experience with the cold whatsoever. He was a college student attending Penn State University. After Justin's friend, Jarrett, showed him one of Wim's videos on You-Tube, he became exceedingly interested in understanding this ability. He wanted to see if it was possible for anyone to learn. In Spring 2010, after speaking to Wim for several months via email, Wim invited Justin to attend his workshop in Poland. After many weeks of working as a dishwasher, Justin was able to pay for the trip and learn the technique of the Iceman.With more training and countless experiences with the cold, Justin began to slowly adapt. The length of time he could remain exposed increased dramatically. He quickly realized that the technique to withstand the cold was, indeed, an ability that could be learned by everyone. This book tells the tale of Wim a

    Children are given a well-rounded understanding of this beautiful fish: its anatomy, feeding habits and behavior. The following Sharks are featured:* The swift Black Tip Reef Shark* The dangerous Bull Shark* The resourceful Hammerhead Shark* The feared Great White Shark* The stealthy Lemon Shark* The fanged Nurse Shark* The gentle Whale Shark* The deceptive Wobbegong

    

    People need cheering up. I have the answer. ‘Pills, Thrills and Methadone Spills: Adventures of a Community Pharmacist’ is a collection of the best blogs, tweets and anecdotes about the wonderful world of pharmacy.“If the shutter is three quarters down, then we are shut and not just vertically challenged”...“Gave me huge insight into the ‘real’ world of community pharmacy – I didn’t realise just how much pharmacists deal with on a day to day basis, so for me this was very informative, but in a reallyclever, and massively funny way!” Lucy Pitt, Marketing Manager, The Pharmacy Show“As well as being brilliantly funny, this book is a refreshingly honest view of the world of pharmacy. From student pharmacists to the fully-qualified, every chapter provides a story that the reader can relate to and enjoy.” Georgia Salter, Pharmacy Student“A well observed reflection of life in pharmacy with very funny reflections” Catherine Duggan, Royal Pharmaceutical Society"It is always fun to be reminded that pharmacists' perils and fun at the workplace are similar irrespective of which country we practise in!" Selina Hui-Hoong Wee , Pharmacist, Malaysia“A great entertaining and amusing read" Mike Holden, Chief Executive, National Pharmacy AsociationThanks to Laura Martins for her initial book cover design!

    Numerous tables and figures.

    This new edition continues to offer the most complete technology/new media support package available. That technology/new media package includes: Interactives, Animations, and introducing Connect - online homework and course management.