Everything in Its Place is a celebration of Sacks's myriad interests, all told with his characteristic compassion, erudition, and luminous prose. From the celebrated case history of Spalding Gray that appeared in The New Yorker four months before his death to reflections on mental asylums; from piercing accounts of Schizophrenia to a reminiscence of Robin Williams; from the riveting tale of a medical colleague falling victim to Alzheimer's to the cinematography of Michael Powell, this volume celebrates and reflects the wondrous curiosity of Oliver Sacks.

    Difficulty breathing. Overwhelming dread. Andrea Petersen was first diagnosed with an anxiety disorder at the age of twenty, but she later realized that she had been experiencing panic attacks since childhood. With time her symptoms multiplied. She agonized over every odd physical sensation. She developed fears of driving on highways, going to movie theaters, even licking envelopes. Although having a name for her condition was an enormous relief, it was only the beginning of a journey to understand and master it—one that took her from psychiatrists’ offices to yoga retreats to the Appalachian Trail. Woven into Petersen’s personal story is a fascinating look at the biology of anxiety and the groundbreaking research that might point the way to new treatments. She compares psychoactive drugs to non-drug treatments, including biofeedback and exposure therapy. And she explores the role that genetics and the environment play in mental illness, visiting top neuroscientists and tracing her family history—from her grandmother, who, plagued by paranoia, once tried to burn down her own house, to her young daughter, in whom Petersen sees shades of herself. Brave and empowering, this is essential reading for anyone who knows what it means to live on edge.

    Perry Baird was a rising medical star in the late 1920s and 1930s. Early in his career, ahead of his time, he grew fascinated with identifying the biochemical root of manic depression, just as he began to suffer from it himself. By the time the results of his groundbreaking experiments were published, Dr. Baird had been institutionalized multiple times, his medical license revoked, and his wife and daughters estranged. He later received a lobotomy and died from a consequent seizure, his research incomplete, his achievements unrecognized.Mimi Baird grew up never fully knowing this story, as her family went silent about the father who had been absent for most of her childhood. Decades later, a string of extraordinary coincidences led to the recovery of a manuscript which Dr. Baird had worked on throughout his brutal institutionalization, confinement, and escape. This remarkable document, reflecting periods of both manic exhilaration and clear-headed health, presents a startling portrait of a man who was a uniquely astute observer of his own condition, struggling with a disease for which there was no cure, racing against time to unlock the key to treatment before his illness became impossible to manage.Fifty years after being told her father would forever be “ill” and “away,” Mimi Baird set off on a quest to piece together the memoir and the man. In time her fingers became stained with the lead of the pencil he had used to write his manuscript, as she devoted herself to understanding who he was, why he disappeared, and what legacy she had inherited. The result of his extraordinary record and her journey to bring his name to light is He Wanted the Moon, an unforgettable testament to the reaches of the mind and the redeeming power of a determined heart.Soon to be a major motion picture, from Brad Pitt and Tony Kushner

    By all appearances, she had mastered being a grown-up. But beneath that veneer of success, she was a chronically anxious, self-medicating mess. No one knew that her road to adulthood had been paved with depression, anxiety, and shame, owing in large part to her minimally parented upbringing. She realized she’d hit rock bottom when she drunk-dialed her therapist pleading for help.Buy Yourself the F*cking Lilies is the story of Tara’s path to re-parenting herself and becoming a “ninja of self-love.” Through simple, daily rituals, Tara transformed her mind, body, and relationships, and shows how to:• fake gratitude until you actually feel gratitude• excavate your emotional wounds and heal them with kindness• identify your self-limiting beliefs, kick them to the curb, and start living a life you choose• silence your inner frenemy and shield yourself from self-criticism• carve out time each morning to start your day empowered, inspired, and ready to rule• create a life you truly, totally f*cking LOVEThis is the book Tara wished someone had given her and it is the book many of us desperately need: a candid, hysterical, addictively readable, practical guide to growing up (no matter where you are in life) and learning to love yourself in a non-throw-up-in-your-mouth-it’s-so-cheesy way.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    As Dr. Kent Kiehl shows, psychopaths can be identified by a checklist of symptoms that includes pathological lying; lack of empathy, guilt, and remorse; grandiose sense of self-worth; manipulation; and failure to accept one’s actions. But why do psychopaths behave the way they do? Is it the result of their environment— how they were raised—or is there a genetic compo­nent to their lack of conscience? This is the question Kiehl, a protégé of famed psychopath researcher Dr. Robert Hare, was deter­mined to answer as he began his career twenty years ago. To aid in his quest to unravel the psy­chopathic mind, Kiehl created the first mobile functional MRI scanner to study psychopaths in prison populations. The brains of more than five hundred psychopaths and three thousand other offenders have been scanned by Kiehl’s labora­tory—the world’s largest forensic neuroscience repository of its kind. Over the course of The Psy­chopath Whisperer, we follow the scientific bread crumbs that Kiehl uncovered to show that the key brain structures that correspond with emotional engagement and reactions are diminished in psy­chopaths, offering new clues to how to predict and treat the disorder. In The Psychopath Whisperer, Kiehl describes in fascinating detail his years working with psy­chopaths and studying their thought processes— from the remorseless serial killers he meets with behind bars to children whose behavior and per­sonality traits exhibit the early warning signs of psychopathy. Less than 1 percent of the general population meets the criteria for psychopathy. But psycho­paths account for a vastly outsized proportion of violent crimes. And as Kiehl shows, many who aren’t psychopaths exhibit some of the behaviors and traits associated with the condition. What do you do if you discover your roommate, or boss, or the person you are dating has traits that define a psy­chopath? And what does having a diminished limbic region of the brain mean for how the legal system approaches crimes committed by psychopaths? A compelling narrative of cutting-edge science, The Psychopath Whisperer will open your eyes on a fascinating but little understood world, with startling implications for society, the law, and our personal lives.

    You might even be worried that these lapses in memory could be an early sign of Alzheimer's or dementia. In reality, for the vast majority of us, these examples of forgetting are completely normal. Why? Because while memory is amazing, it is far from perfect. Our brains aren't designed to remember every name we hear, plan we make, or day we experience. Just because your memory sometimes fails doesn't mean it's broken or succumbing to disease. Forgetting is actually part of being human. In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car). And you'll see how memory is profoundly impacted by meaning, emotion, sleep, stress, and context. Once you understand the language of memory and how it functions, its incredible strengths and maddening weaknesses, its natural vulnerabilities and potential superpowers, you can both vastly improve your ability to remember and feel less rattled when you inevitably forget. You can set educated expectations for your memory, and in doing so, create a better relationship with it. You don't have to fear it anymore. And that can be life-changing.

    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.

    Yet somehow, this normal boy became one of the youngest people on whom Dr. Walter Freeman performed his barbaric transorbital—or ice pick—lobotomy.Abandoned by his family within a year of the surgery, Howard spent his teen years in mental institutions, his twenties in jail, and his thirties in a bottle. It wasn’t until he was in his forties that Howard began to pull his life together. But even as he began to live the “normal” life he had been denied, Howard struggled with one question: Why?“October 8, 1960. I gather that Mrs. Dully is perpetually talking, admonishing, correcting, and getting worked up into a spasm, whereas her husband is impatient, explosive, rather brutal, won’t let the boy speak for himself, and calls him numbskull, dimwit, and other uncomplimentary names.”There were only three people who would know the truth: Freeman, the man who performed the procedure; Lou, his cold and demanding stepmother who brought Howard to the doctor’s attention; and his father, Rodney. Of the three, only Rodney, the man who hadn’t intervened on his son’s behalf, was still living. Time was running out. Stable and happy for the first time in decades, Howard began to search for answers. “December 3, 1960. Mr. and Mrs. Dully have apparently decided to have Howard operated on. I suggested [they] not tell Howard anything about it.”Through his research, Howard met other lobotomy patients and their families, talked with one of Freeman’s sons about his father’s controversial life’s work, and confronted Rodney about his complicity. And, in the archive where the doctor’s files are stored, he finally came face to face with the truth.Revealing what happened to a child no one—not his father, not the medical community, not the state—was willing to protect, My Lobotomy exposes a shameful chapter in the history of the treatment of mental illness. Yet, ultimately, this is a powerful and moving chronicle of the life of one man. Without reticence, Howard Dully shares the story of a painfully dysfunctional childhood, a misspent youth, his struggle to claim the life that was taken from him, and his redemption.

    His new and initially intimidating classmates were high achievers from the Ivy League and other elite universities around the nation. Stern pulls back the curtain on the intense and emotionally challenging lessons he and his fellow doctors learned while studying the human condition, and ultimately, the value of connection. The narrative focuses on these residents, their growth as doctors, and the life choices they make as they try to survive their grueling four-year residency. Most importantly, as they study how to help distressed patients in search of a better life, they discover the meaning of failure and the preciousness of success.

    Armstrong writes about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. This book recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.

    There have been exhilarating highs and devastating lows, but his love for the practice of neurosurgery has never wavered. Following the publication of his celebrated New York Times bestseller Do No Harm, Marsh retired from his full-time job in England to work pro bono in Ukraine and Nepal. In Admissions, he describes the difficulties of working in these troubled, impoverished countries and the further insights it has given him into the practice of medicine. Marsh also faces up to the burden of responsibility that can come with trying to reduce human suffering. Unearthing memories of his early days as a medical student and the experiences that shaped him as a young surgeon, he explores the difficulties of a profession that deals in probabilities rather than certainties and where the overwhelming urge to prolong life can come at a tragic cost for patients and those who love them. Reflecting on what forty years of handling the human brain has taught him, Marsh finds a different purpose in life as he approaches the end of his professional career and a fresh understanding of what matters to us all in the end.

    . . . I want to have words for what my bones know."By age thirty, Stephanie Foo was successful on paper: She had her dream job as an award-winning radio producer at This American Life and a loving boyfriend. But behind her office door, she was having panic attacks and sobbing at her desk every morning. After years of questioning what was wrong with herself, she was diagnosed with complex PTSD--a condition that occurs when trauma happens continuously, over the course of years.Both of Foo's parents abandoned her when she was a teenager, after years of physical and verbal abuse and neglect. She thought she'd moved on, but her new diagnosis illuminated the way her past continued to threaten her health, relationships, and career. She found limited resources to help her, so Foo set out to heal herself, and to map her experiences onto the scarce literature about C-PTSD.In this deeply personal and thoroughly researched account, Foo interviews scientists and psychologists and tries a variety of innovative therapies. She returns to her hometown of San Jose, California, to investigate the effects of immigrant trauma on the community, and she uncovers family secrets in the country of her birth, Malaysia, to learn how trauma can be inherited through generations. Ultimately, she discovers that you don't move on from trauma--but you can learn to move with it.Powerful, enlightening, and hopeful, What My Bones Know is a brave narrative that reckons with the hold of the past over the present, the mind over the body--and examines one woman's ability to reclaim agency from her trauma.

    But in The Night the Lights Went Out, he finds himself far out of his depths. On the night of the 2018 Deadspin Awards, he suffered a mysterious fall that caused him to smash his head so hard on a cement floor that he cracked his skull in three places and suffered a catastrophic brain hemorrhage. For two weeks, he remained in a coma. The world was gone to him, and him to it.In his long recovery from his injury, including understanding what his family and friends went through as he lay there dying, coming to terms with his now permanent disabilities, and trying to find some lesson in this cosmic accident, he leaned on the one sure thing that he knows and that didn't leave him--his writing.Drew takes a deep dive into what it meant to be a bystander to his own death and figuring out who this new Drew is: a Drew that doesn't walk as well, doesn't taste or smell or see or hear as well, and a Drew that is often failing as a husband and a father as he bounces between grumpiness, irritability, and existential fury. But what's a good comeback story without heartbreak? Eager to get back what he lost, Drew experiences an awakening of a whole other kind in this incredibly funny, medically illuminating, and heartfelt memoir.

    From miraculous pregnancies to dirty protests, and from violent attacks on prisoners to heartbreaking acts of self-harm, she has witnessed it all. In this memoir, Amanda reveals the stories, the patients and the cases that have shaped a career helping those most of us would rather forget.