Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation? In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients—a Biotech Social Contract. Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including: Why doesn’t insurance make drugs affordable? How can we prevent price-jacking of older drugs? Why are drugs more expensive in America than elsewhere? How can we guarantee that all medicines eventually go generic so they are only temporarily expensive? What systemic failures led to the opioid crisis, and how can we prevent the next one? The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.

    It remains an elementary and non-mathematical introduction to molecular spectroscopy that emphasizes the overall unity of the subject and offers a pictorial perception rather than a mathematical description of the principles of spectroscopy.

    Features exceptionally clear explanations and descriptions, step-by-step examples, more than 50 practical applications, over 2000 easy-to-challenging practice problems, and comprehensive coverage of essentials. PSpice, OrCAd version 9.2 Lite Edition, Multisims 2001 version of Electronics Workbench, and MathCad software references and examples are used throughout. Computer programs (C++, BASIC and PSpice) are printed in color, as they run, at the point in the book where they are discussed. Current and Voltage. Resistance. Ohm's Law, Power, and Energy. Series Circuits. Parallel Circuits. Series-Parallel Networks. Methods of Analysis & Selected Topics. Network Theorems. Capacitors. Magnetic Circuits. Inductors. Sinusodial Alternating Waveforms. The Basic Elements and Phasors. Series and Parallel ac Circuits. Series-Parallel ac Networks. Methods of Analysis and Related Topics. Network Theorems (ac). Power (ac). Resonance. Transformers. Polyphase Systems. Decibels, Filters, and Bode Points. Pulse Waveforms and the R-C Response. Nonsinusodial Circuits. System Analysis: An Introduction. For those working in electronic technology.

    Like many others, I feel like I have learned more in the last couple of years studying Bitcoin than I have during two decades of formal education. The following lessons are a distillation of what I’ve learned. First published as an article series titled “What I’ve Learned From Bitcoin,” what follows can be seen as a third edition of the original series. Like Bitcoin, these lessons aren’t a static thing. I plan to work on them periodically, releasing updated versions and additional material in the future.Bitcoin is an inexhaustible teacher, which is why I do not claim that these lessons are all-encompassing or complete. They are a reflection of my personal journey down the rabbit hole. There are many more lessons to be learned, and every person will learn something different from entering the world of Bitcoin. I hope that you will find these lessons useful and that the process of learning them by reading won’t be as arduous and painful as learning them firsthand.

    

    The consequences of this gathering may be enormous. In this new ebook, experts Patrick J. Michaels and Paul C. Knappenberger assess the issues sure to drive the debate before, during, and after the Paris meeting.

    “The result is a veritable pi

    The army blamed “human error†and a sordid love triangle. Though overshadowed by Three Mile Island, SL-1 remains the only fatal nuclear reactor incident in American history. Todd Tucker, who first heard the rumors about the Idaho Falls explosion as a trainee in the navy’s nuclear program, suspected there was more to the accident than rumors suggested. Poring over hundreds of pages of primary sources and interviewing survivors revealed that the army and its contractors had deliberately obscured the true cause of the accident, which resulted from poor engineering as much as uncontrolled passions. The National Reactor Testing Station, where the meltdown occurred, had been a proving ground where engineers, generals, and admirals attempted to realize the Atomic Age dream of unlimited power—amid the frantic race for nuclear power between the army, the navy, and the air force. The fruit of those ambitious plans included that of the nation’s unofficial nuclear patriarch, Admiral Rickover, whose “true submarine,†the USS Nautilus, would forever change naval warfare. But with the meltdown in Idaho came the end of the army’s program and the beginning of the navy’s long-standing monopoly on military nuclear power. Atomic America provides a fast-paced narrative history, advocating caution and accountability in harnessing nuclear energy.

    From humorous fishing excursions and frightening bear encounters to snow blinding blizzards and quirky characters, they come face to face with the unpredictable Mother Nature and learn the value of friendship, survival, and solitude in a picturesque but harsh life by the sea. Packed with adventures, challenges, and true Alaskan lifestyle.

    This new edition simplifies many of the steps involved in analysis by using the computer application Excel. Over 100 detailed example problems illustrate important fluid mechanics concepts: Approximately 1300 end-of-chapter problems are arranged by difficulty level and include many problems that are designed to be solved using Excel. The CD for the book includes: A Brief Review of Microsoft Excel and numerous Excel files for the example problems and for use in solving problems. The new edition includes an expanded discussion of pipe networks, and a new section on oblique shocks and expansion waves.

    This edition features new material on Controls, Computer-Aided Design and Manufacturing, and Off-Line Programming Systems.

    With its modern emphasis on the molecular view of physical chemistry, its wealth of contemporary applications (in the new "Impact on" features), vivid full-color presentation, and dynamic new media tools, the thoroughly revised new edition is again the most modern, most effective full-length textbook available for the physical chemistry classroom. NOW AVAILABLE IN SPLIT VOLUMESFor maximum flexibility in your physical chemistry course, this text isnow offered as a traditional or in two volumes.• Volume 1:  Thermodynamics and Kinetics (ISBN 0-7167-8567-6)• Volume 2:  Quantum Chemistry, Spectroscopy, and StatisticalThermodynamics (ISBN 0-7167-8569-2)See Table of Contents for the contents of each volume.

    At the time we were hoping that our approach of writing a book which would be both accessible without mathematical sophistication and portray these exiting new fields in an authentic manner would find an audience. Now we know it did. We know from many reviews and personal letters that the book is used in a wide range of ways: researchers use it to acquaint themselves, teachers use it in college and university courses, students use it for background reading, and there is also a substantial audience of lay people who just want to know what chaos and fractals are about. Every book that is somewhat technical in nature is likely to have a number of misprints and errors in its first edition. Some of these were caught and brought to our attention by our readers. One of them, Hermann Flaschka, deserves to be thanked in particular for his suggestions and improvements. This second edition has several changes. We have taken out the two appendices from the firstedition. At the time of the first edition Yuval Fishers contribution, which we published as an appendix was probably the first complete expository account on fractal image compression. Meanwhile, Yuvals book Fractal Image Compression: Theory and Application appeared and is now the publication to refer to.

    Emphasis is placed upon the theoretical basis of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations. The text also introduces students to elementary integrated circuitry, microprocessors and computers, and treatment of analytical data.

    It provides a realistic, informative, and positive introduction to the practice of chemical engineering.