Two men, known in medical journals as the Berlin Patients, revealed answers to a functional cure for HIV. Their cures came twelve years apart, the first in 1996 and the second in 2008. Each received his own very different treatment in Berlin, Germany, and each result spurred a new field of investigation, fueling innovative lines of research and sparking hope for the thirty-four million people currently infected with HIV. For the first time, Nathalia Holt, who has participated in some of the most fruitful research in the field, tells the story of how we came to arrive at this astounding and controversial turning point. Holt explores the two men’s stories on a personal level, looking at how their experiences have influenced HIV researchers worldwide—including one very special young family doctor who took the time to look closely at his patients—and how they responded to their medications. Based on extensive interviews with the patients and their doctors as well as her own in-depth research, this book is an unprecedented look at how scientists pursue their inquiries, the human impact their research has, and what is and is not working in the relationship between Big Pharma and medical care.

    But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

    This is an incredible true account of investigative journalism and a devastating indictment of energy politics in America.Stacey Haney, a lifelong resident of Amity, Pennsylvania, is struggling to support her children when the fracking boom comes to town. Like most of her neighbors, she sees the energy companies' payments as a windfall. Soon trucks are rumbling down her unpaved road and a fenced-off fracking site rises on adjacent land. But her annoyance gives way to concern and then to fear as domestic animals and pets begin dying and mysterious illnesses strike her family--despite the companies' insistence that nothing is wrong.Griswold masterfully chronicles Haney's transformation into an unlikely whistle-blower as she launches her own investigation into corporate wrongdoing. As she takes her case to court, Haney inadvertently reveals the complex rifts in her community and begins to reshape its attitudes toward outsiders, corporations, and the federal government. Amity and Prosperity uses her gripping and moving tale to show the true costs of our energy infrastructure and to illuminate the predicament of rural America in the twenty-first century.

    It took him from the colossal supermarkets of California to India’s wrecked paddy-fields and Africa’s bankrupt coffee farms, while along the way he ate genetically engineered soy beans and dodged flying objects in the protestor-packed streets of South Korea.What he found was shocking, from the false choices given us by supermarkets to a global epidemic of farmer suicides, and real reasons for famine in Asia and Africa.Yet he also found great cause for hope—in international resistance movements working to create a more democratic, sustainable and joyful food system. Going beyond ethical consumerism, Patel explains, from seed to store to plate, the steps to regain control of the global food economy, stop the exploitation of both farmers and consumers, and rebalance global sustenance.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    Unable to stand, barely able to think, he waited for hours in an emergency room before being correctly diagnosed and rushed into surgery. Over the next few days, as he clung to life and the first light of a new year came through his window, he found himself reflecting on the fragility of health, not recognized in America as a human right but without which all rights and freedoms have no meaning.And that was before the pandemic. We have since watched American hospitals, long understaffed and undersupplied, buckling under waves of coronavirus patients. The federal government made matters worse through willful ignorance, misinformation, and profiteering. Our system of commercial medicine failed the ultimate test, and thousands of Americans died.In this eye-opening cri de coeur, Snyder traces the societal forces that led us here and outlines the lessons we must learn to survive. In examining some of the darkest moments of recent history and of his own life, Snyder finds glimmers of hope and principles that could lead us out of our current malaise. Only by enshrining healthcare as a human right, elevating the authority of doctors and medical knowledge, and planning for our children's future can we create an America where everyone is truly free.

    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.

    Throughout our life, we look for ways to keep our mind sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and cognitive decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the only owner’s manual you’ll need to keep your brain young and healthy regardless of your age!

    The reality of being poor brings out a survival mentality, and turns attention away from opportunities taken for granted by everyone else. If you work with people from poverty, some understanding of how different their world is from yours will be invaluable. Whether you're an educator--or a social, health, or legal services professional--this breakthrough book gives you practical, real-world support and guidance to improve your effectiveness in working with people from all socioeconomic backgrounds. Since 1995 A Framework for Understanding Poverty has guided hundreds of thousands of educators and other professionals through the pitfalls and barriers faced by all classes, especially the poor. Carefully researched and packed with charts, tables, and questionnaires, Framework not only documents the facts of poverty, it provides practical yet compassionate strategies for addressing its impact on people's lives.

    Here is the sweeping story of a substance that has been feared, revered, mythologized, and used in magic and medicine from earliest times--a substance that has become the center of a huge, secretive, and often dangerous worldwide commerce.Winner of the Los Angeles Times Book Prize, Blood was described by judges as "a gripping page-turner, a significant contribution to the history of medicine and technology and a cautionary tale. Meticulously reported and exhaustively documented."

    coli as the culprit, and the legal teams on both sides of the historic lawsuits that ensued. This is the story of the permanent transformation of our food supply chain, and the young maverick lawyer, Bill Marler, who staked his career on bringing the victims justice without compromise. Fast Food Nation meets A Civil Action in this riveting account of how we learned the hard way to truly watch what we eat.

    But one rogue researcher looked at the data and decided everyone was wrong. Franz Boas was the very image of a mad scientist: a wild-haired immigrant with a thick German accent. By the 1920s he was also the foundational thinker and public face of a new school of thought at Columbia University called cultural anthropology. He proposed that cultures did not exist on a continuum from primitive to advanced. Instead, every society solves the same basic problems--from childrearing to how to live well--with its own set of rules, beliefs, and taboos.Boas's students were some of the century's intellectual stars: Margaret Mead, the outspoken field researcher whose Coming of Age in Samoa is one of the most widely read works of social science of all time; Ruth Benedict, the great love of Mead's life, whose research shaped post-Second World War Japan; Ella Deloria, the Dakota Sioux activist who preserved the traditions of Native Americans of the Great Plains; and Zora Neale Hurston, whose studies under Boas fed directly into her now-classic novel, Their Eyes Were Watching God. Together, they mapped vanishing civilizations from the Arctic to the South Pacific and overturned the relationship between biology and behavior. Their work reshaped how we think of women and men, normalcy and deviance, and re-created our place in a world of many cultures and value systems. Gods of the Upper Air is a page-turning narrative of radical ideas and adventurous lives, a history rich in scandal, romance, and rivalry, and a genesis story of the fluid conceptions of identity that define our present moment.

    . . Health care executives pulling in millions in bonuses for denying treatment to the sick . . . More than 100 million people with inadequate or no medical coverage . . . This may sound like the predicament of a third-world nation, but this is America’s health care reality today. The U.S. spends more on health care than any other nation, yet our benefits are shrinking and life expectancy is shorter here than in countries that spend significantly less per capita. Meanwhile, HMOs, pharmaceutical companies, and hospital chains reap tremendous profits, while politicians—beholden to insurers and drug companies—enact legislation for the benefit of the few rather than the many, while the entire system is on the verge of collapse. In Critical Condition, award-winning investigative journalists Donald L. Barlett and James B. Steele expose the horror of what health care in America has become. They profile patients and doctors trapped by the system and offer startling personal stories that illuminate what’s gone wrong. Doctors tell of being second-guessed and undermined by health care insurers; nurses recount chilling tales of hospital meltdowns; patients explain how they’ve been victimized by a system that is meant to care for them. Drug companies profit by selling pills in the same manner that Madison Avenue sells soap, while Wall Street rakes in billions by building up and then tearing down health care businesses. And politicians pass legislation perpetuating the injustices and out-right fraud the system encourages. By analyzing the industry and offering an insightful prescription for getting it back on the right track, Critical Condition is an enormously compelling investigative work that addresses the concerns of every American.

    We are bombarded with more information each day than our brains can process—especially in election season. It's raining bad data, half-truths, and even outright lies. New York Times bestselling author Daniel J. Levitin shows how to recognize misleading announcements, statistics, graphs, and written reports revealing the ways lying weasels can use them. It's becoming harder to separate the wheat from the digital chaff. How do we distinguish misinformation, pseudo-facts, distortions, and outright lies from reliable information? Levitin groups his field guide into two categories—statistical infomation and faulty arguments—ultimately showing how science is the bedrock of critical thinking. Infoliteracy means understanding that there are hierarchies of source quality and bias that variously distort our information feeds via every media channel, including social media. We may expect newspapers, bloggers, the government, and Wikipedia to be factually and logically correct, but they so often aren't. We need to think critically about the words and numbers we encounter if we want to be successful at work, at play, and in making the most of our lives. This means checking the plausibility and reasoning—not passively accepting information, repeating it, and making decisions based on it. Readers learn to avoid the extremes of passive gullibility and cynical rejection. Levitin's charming, entertaining, accessible guide can help anyone wake up to a whole lot of things that aren't so. And catch some lying weasels in their tracks!

    Yet despite the devastation, this catastrophic event seems but a forgotten moment in the United States.American Pandemic offers a much-needed corrective to the silence surrounding the influenza outbreak. It sheds light on the social and cultural history of Americans during the pandemic, uncovering both the causes of the nation's public amnesia and the depth of the quiet remembering that endured. Focused on the primary players in this drama--patients and their families, friends, and community, public health experts, and health care professionals--historian Nancy K. Bristow draws on multiple perspectives to highlight the complex interplay between social identity, cultural norms, memory, and the epidemic. Bristow has combed a wealth of primary sources, including letters, diaries, oral histories, memoirs, novels, newspapers, magazines, photographs, government documents, and health care literature. She shows that though the pandemic caused massive disruption in the most basic patterns of American life, influenza did not create long-term social or cultural change, serving instead to reinforce the status quo and the differences and disparities that defined American life.As the crisis waned the pandemic slipped from the nation's public memory. The helplessness and despair Americans had suffered during the pandemic, Bristow notes, was a story poorly suited to a nation focused on optimism and progress. For countless survivors, though, the trauma never ended, shadowing the remainder of their lives with memories of loss. This book lets us hear these long-silent voices, reclaiming an important chapter in the American past.