We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    This new edition continues the LWW focus on providing accurate, up-to-date, and practical instruction in phlebotomy procedures and techniques, grounded by a comprehensive background in phlebotomy theory. Key additions include updated information on the latest CLSI guidelines, new media to accompany each chapter, more color photos, and the addition of terms to align the text with the International Standards Organization (ISO).Written to be highly accessible to students at all levels, and comprehensive enough for practicing phlebotomists, this text is complemented by a robust ancillary suite to help readers of all learning styles master the material. The online ancillaries, coupled with the text and available workbook and exam review book, help create a dynamic phlebotomy learning experience.

    Encompassing recent advances in molecular pharmacology and brain imaging, Drugs, The Brain and Behavior offers a unique breadth of coverage from historical accounts of drug use, through clinical and preclinical behavioural studies, to the latest research on drug effects in transgenic mouse models.

    

    The most trusted sources in the auto industry have called its Model S the most advanced, safest and best-performing car ever built - and it doesn’t use a drop of gasoline. Tesla has changed the way the public perceives electric vehicles, and inspired the major automakers to revive their own dormant efforts to sell EVs. However, even amidst the avalanche of media coverage that followed the triumph of the Model S, few have grasped the true significance of what is happening. Tesla has redefined the automobile, sparked a new wave of innovation comparable to the internet and mobile computing revolutions, and unleashed forces that will transform not just the auto industry, but every aspect of society. The Tesla story is one part of an ongoing tide of change driven by the use of information technology to eliminate “friction” such as geographic distance, middlemen and outdated regulations. Tesla is simply applying the new order to the auto industry, but the automobile is such a pervasive influence in our lives that redefining how it is designed, built, driven and sold will have sweeping effects in unexpected areas. Just as Tesla built the Model S as an electric vehicle “from the ground up,” it has taken an outsider’s approach to the way it markets its cars. Its direct sales model has drawn legal challenges from entrenched auto dealers, who fear that their outdated business model will be destroyed. Its systems approach to the software and electronics in its cars has highlighted how far behind the technological times the major automakers are. It’s easy to see why readers find Tesla irresistible. CEO Elon Musk is a superstar entrepreneur, a “nauseatingly pro-US” immigrant and the leader of two other cutting-edge companies. Tesla dares to challenge the establishment behemoths and, so far at least, has handily beaten them at their own game. In this history of the 21st century’s most exciting startup, Charles Morris begins with a brief history of EVs and a biography of Tesla’s driving force, Elon Musk. He then details the history of the company, told in the words of the Silicon Valley entrepreneurs who made it happen. There are many fascinating stories here: Martin Eberhard’s realization that there were many like himself, who loved fast cars but wanted to help the environment and bring about the post-oil age; the freewheeling first days, reminiscent of the early internet era; the incredible ingenuity of the team who built the Roadster; Tesla’s near-death experience and miraculous resurrection; the spiteful split between the company’s larger-than-life leaders; the gloves-off battles with hostile media such as Top Gear and the New York Times; and the media’s ironic about-face when the magnificent Model S won the industry’s highest honors, and naysayers became cheerleaders overnight. And the story is just beginning: Tesla has breathtakingly ambitious plans for the future.This book was updated May 1, 2015 to include the latest on the Gigafactory and the D package.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.

    Over 80 per cent of adults in the UK use caffeine every day, but when does this habit become a reliance? Caffeine is a bitter addictive drug which attacks the central nervous system and makes you jittery. Fooling you into thinking you are more alert, caffeine will often disrupt your sleep and actually increase overall fatigue. Quite simply, it's bad for you with no real benefits.In The Easy Way to Quit Caffeine, Allen Carr addresses the difficulties that coffee-drinkers and soda consumers face in trying to quit caffeine. By explaining what caffeine does to your body, and providing simple step-by-step instructions to free you from your addiction, Carr shows you how to lead a happier, healthier and more chilled life.

    This is an increase of over 500% since 1980 and the numbers continue to grow. Yet, despite this prescription epidemic, levels of mental illness of all types have actually increased in number and severity.Using a wealth of studies, interviews with experts, and detailed analysis, Dr James Davies argues that this is because we have fundamentally mischaracterised the problem. Rather than viewing most mental distress as an understandable reaction to wider societal problems, we have embraced a medical model which situates the problem solely within the sufferer and their brain.Urgent and persuasive, Sedated systematically examines why this individualistic view of mental illness has been promoted by successive governments and big business – and why it is so misplaced and dangerous.

    Bonnie Henry has been called one of the most effective public health figures in the world by The New York Times. She has been called a calming voice in a sea of coronavirus madness, and our hero in national newspapers. But in the waning days of 2019, when the first rumours of a strange respiratory ailment in Wuhan, China began to trickle into her office in British Colombia, these accolades lay in a barely imaginable future.Only weeks later, the whole world would look back on the previous year with the kind of nostalgia usually reserved for the distant past. With a staggering suddenness, our livelihoods, our closest relationships, our habits and our homes had all been transformed.In a moment when half-truths threatened to drown out the truth, when recklessness all too often exposed those around us to very real danger, and when it was difficult to tell paranoia from healthy respect for an invisible threat, Dr. Henry's transparency, humility, and humanity became a beacon for millions of Canadians.And her trademark enjoinder to be kind, be calm, and be safe became words for us all to live by.Coincidentally, Dr. Henry's sister, Lynn, arrived in BC for a long-planned visit on March 12, just as the virus revealed itself as a pandemic. For the four ensuing weeks, Lynn had rare insight into the whirlwind of Bonnie's daily life, with its moments of agony and gravity as well as its occasional episodes of levity and grace. Both a global story and a family story, Be Kind, Be Calm, Be Safe combines Lynn's observations and knowledge of Bonnie's personal and professional background with Bonnie's recollections of how and why decisions were made, to tell in a vivid way the dramatic tale of the four weeks that changed all our lives.Be Kind, Be Calm, Be Safe is about communication, leadership, and public trust; about the balance between politics and policy; and, at heart, about what and who we value, as individuals and a society.The authors' advance from the publisher will be donated to charities with a focus on alleviating communities hit particularly hard by the pandemic: True North Aid with its Covid-19 response in Northern Indigenous communities, and First Book Canada, with its focus on reading and literacy for underserved, marginalized youth.

    Demystifying DSM-5 criteria without sacrificing accuracy, the book includes ICD-10-CM codes for each disorder. More than 130 detailed case vignettes illustrate typical patient presentations; down-to-earth discussions of each case demonstrate how to arrive at the diagnosis and rule out other likely possibilities. Providing a wealth of diagnostic pointers, Morrison writes with the wisdom and wit that made his guide to the prior DSM a valued resource for hundreds of thousands of clinicians and students. His website (www.guilford.com/jm) offers additional discussion and resources related to psychiatric diagnosis and DSM-5. See also Morrison's Diagnosis Made Easier, Second Edition, which offers principles and decision trees for integrating diagnostic information from multiple sources; The First Interview, Fourth Edition, which presents a framework for conducting thorough, empathic initial evaluations; and The Mental Health Clinician's Workbook, which uses in-depth cases and carefully constructed exercises to build the reader's diagnostic skills.

    From Mary Lamb, sister of Charles, who in the throes of a nervous breakdown turned on her mother with a kitchen knife, to Freud, Jung, and Lacan, who developed the new women-centered therapies, Lisa Appignanesi’s research traces how more and more of the inner lives and emotions of women have become a matter for medics and therapists. Here too is the story of how over the years symptoms and diagnoses have developed together to create fashions in illness and how treatments have succeeded or sometimes failed. Mad, Bad, and Sad takes us on a fascinating journey through the fragile, extraordinary human mind.

     Jacob Sullum goes beyond the debate on legalization or the proper way to win the "war on drugs," to the heart of a social and individual defense of using drugs. Saying Yes argues that the all-or-nothing thinking that has long dominated discussions of illegal drug use should give way to a wiser, subtler approach exemplified by the tradition of moderate drinking. Saying Yes further contends that the conventional understanding of addiction, portraying it as a kind of chemical slavery in which the user's values and wishes do not matter, is also fundamentally misleading.

    Made from the ayahuasca vine and the leaves of a shrub, ayahuasca is increasingly known as a powerful tool for personal transformation that more and more Westerners are flocking to drink in a quest for greater self-knowledge, healing and a reconnection with the natural world.The formerly esoteric, little-known brew is spearheading a global psychedelic renaissance unlike anything seen since the 1960s – but why?Pinchbeck and Rokhlin explore the cultural and historical origins of the plant, considering the role of the shaman or curandero in Amazonian and Western cultures. They follow the surprising story of ayahuasca as it twines across the world, examining its current legal status and reviewing up-to-date biomedical research and psychedelic science, whilst looking closely at how ayahuasca is perceived and used today.When Plants Dream explores the economic, social, political and environmental impact that ayahuasca is having on cultures beyond the Amazon.

    Weekly as "the culture's foremost spokesman for the psychedelic experience," Terrence McKenna is an underground legend as a brilliant raconteur, adventurer & expert on the experiential use of mind-altering plants. In these essays, interviews & narrative adventures, McKenna takes us on a mesmerizing journey deep into the Amazon as well as into the hidden recesses of the human psyche & the outer limits of our culture, giving us startling visions of the past & future.

    Genealogists and adoptees are using them and other DNA tests to identify ancestors, confirm relationships, and measure their ethnicity. Unfortunately, there are many similar sounding tests and some of them have different testing levels. So it’s easy to order the wrong test or pay too much. This Guide to DNA Testing provides an easy-to-understand introduction to the different test types, their strengths and limitations. Author and adoptee, Richard Hill, shared his personal success story in his book, "Finding Family: My Search for Roots and the Secrets in My DNA.” Now he boils down the basics of genetic genealogy into this concise summary. Learn which tests are right for you. Hyperlinks to specific tests and resources are included.