It expands on the foundation acquired in chemistry courses and enables students to understand the mechanisms as they come across them in your classroom or laboratory.Organic Reaction Mechanisms provides extensive coverage of various organic reaction and rearrangements with emphasis on their applications in syntheses. The authors discuss reaction pathways, such as substitutions, additions, eliminations, oxidations, reductions, aromatic substitutions, aliphatic nucleophilic substitution, and electrophilic substitutions with numerous reaction equations to show the mechanism. The text also details the various reaction intermediates, including carbocations, carbanions, free radicals, carbenes, nitrines, benzynes, arynes, ylides, and enamines.Furthermore, the reagents are surveyed throughout the text, and correlation tables are provided to aid in identifying which oxidation/reduction agents to use for oxidizing/reducing various types of compounds. The applications of organic reagents are illustrated with examples and problems at the end of each chapter, which also serve to review the mechanisms learned and topics discussed. A comprehensive discussion on organic reactions, Organic Reaction Mechanisms will benefit advanced undergraduate and graduate chemistry students in their understanding and application of organic syntheses.

    This is necessary because, in the words of Michael Polanyi, "we can know more than we can tell." Our design choices are not the result of an ineluctable chain of logic; they come from a deeper place, one which is visceral and inarticulate.Polanyi calls this "tacit knowledge", a thing which we only understand as part of something else. When we speak, we do not focus on making sounds, we focus on our words. We understand the muscular act of speech, but would struggle to explain it.To write software, we must learn where to draw boundaries. Good software is built through effective indirection. We seem to have decided that this skill can only be learned through practice; it cannot be taught, except by example. Our decisions may improve with time, but not our ability to explain them. It's true that the study of these questions cannot yield a closed-form solution for judging software design. We can make our software simple, but we cannot do the same to its problem domain, its users, or the physical world. Our tacit knowledge of this environment will always inform our designs.This doesn't mean that we can simply ignore our design process. Polanyi tells us that tacit knowledge only suffices until we fail, and the software industry is awash with failure. Our designs may never be provably correct, but we can give voice to the intuition that shaped them. Our process may always be visceral, but it doesn't have to be inarticulate.And so this book does not offer knowledge, it offers clarity. It is aimed at readers who know Clojure, but struggle to articulate the rationale of their designs to themselves and others. Readers who use other languages, but have a passing familiarity with Clojure, may also find this book useful.

    Before the Big Bang, there was a tiny fraction of a second during which a process called inflation expanded a seed much smaller than the nucleus of an atom into a fireball the size of a basketball -- the Big Bang itself. From this fireball, the Universe as we know it developed. The origin of the seed from which the Universe began is not known with certainty, but as John Gribbin explains the most likely explanation is that it was a fluctuation of quantum energy in an eternal sea of cosmic energy. And that means that other seeds must surely have inflated to become other universes, bubbles in the cosmic sea. It is even possible that a collision between our universe and another bubble on the sea of eternity may have left an imprint on the cosmic background radiation, the echo of the Big Bang itself. John Gribbin is an award winning science writer best known for his book In Search of Schrodinger's Cat. He studied astrophysics under Fred Hoyle in Cambridge, and is now a Visiting Fellow in Astronomy at the University of Sussex.

    In the 1980s, complexity theory emerged as a powerful alternative to classic, linear thought. A forerunner of that revolution, Fritjof Capra now continues to expand the scope of that theory by establishing a framework in which we can understand and solve some of the most important issues of our time. Capra posits that in order to sustain life, the principles underlying our social institutions must be consistent with the broader organization of nature. Discussing pertinent contemporary issues ranging from the controversial practices of the World Trade Organization (WTO) to the Human Genome Project, he concludes with an authoritative, often provocative plan for designing ecologically sustainable communities and technologies as alternatives to the current economic globalization.

    

    Major concepts are illustrated with running examples, and major algorithms are illustrated by Pascal computer programs. No prior knowledge of GAs or genetics is assumed, and only a minimum of computer programming and mathematics background is required. 0201157675B07092001

    He asks how today's scientists can claim to predict future climate events when even three-day forecasts prove a serious challenge. Can we predict and control epidemics? Can we accurately foresee our financial future? Or will we only find out about tomorrow when tomorrow arrives?

    The twelve-factor app is a methodology for building software-as-a-service apps that: - Use declarative formats for setup automation, to minimize time and cost for new developers joining the project; - Have a clean contract with the underlying operating system, offering maximum portability between execution environments; - Are suitable for deployment on modern cloud platforms, obviating the need for servers and systems administration; - Minimize divergence between development and production, enabling continuous deployment for maximum agility; - And can scale up without significant changes to tooling, architecture, or development practices.The twelve-factor methodology can be applied to apps written in any programming language, and which use any combination of backing services (database, queue, memory cache, etc).

     In this paradigm-shifting book, neurolearning experts Drs. Brock and Fernette Eide describe an exciting new brain science that reveals that dyslexic people have unique brain structure and organization. While the differences are responsible for certain challenges with literacy and reading, the dyslexic brain also gives a predisposition to important skills, and special talents. While dyslexics typically struggle to decode the written word, they often also excel in such areas of reasoning as mechanical (required for architects and surgeons), interconnected (artists and inventors); narrative (novelists and lawyers), and dynamic (scientists and business pioneers). The Dyslexic Advantage provides the first complete portrait of dyslexia.

    The authors acknowledge both the structural and sociological issues that contribute to low-performing schools and offer multiple tools and strategies to assess and improve classroom management, increase literacy, establish academic vocabulary, and contribute to a healthier school culture.

    This instantly useful book is packed with creative examples and powerful best practices that will sharpen your technical skills and inspire your sense of design.Foreword by Chris Coyier, Cofounder of CodePen.Dig even deeper into the secrets of CSS with our video course CSS in Depth in Motion, available exclusively at Manning.com (www.manning.com/livevideo/css-in-dept...)!Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications.About the TechnologySome websites really pop. They look great, they're visually consistent, and they feel interactive and responsive. You can bet their developers knew CSS in depth. CSS specifies everything from the structural layout of page elements to their individual look and feel. True masters know the patterns of CSS development, the techniques to implement them, and the subtle touches that result in beautiful typography, fluid transitions, and balanced graphics. Join them!About the BookCSS in Depth exposes you to a world of CSS techniques that range from clever to mind-blowing. This instantly useful book is packed with creative examples and powerful best practices that will sharpen your technical skills and inspire your sense of design. You'll gain new insights into familiar features like floats and units, and experiment with emerging ideas like responsive design and pattern libraries. Bottom line: this book will make you a better web designer and your apps will look fantastic!What's InsideAvoid common CSS pitfallsMaster misunderstood conceptsUse flexbox and grid layoutResponsive designs for any deviceCode for reuse and maintainabilityAbout the ReaderWritten for web developers who know the basics of CSS and HTML.About the AuthorKeith J. Grant is a senior web developer who builds and maintains web applications and websites, including The New York Stock Exchange site.Table of ContentsPART 1 - REVIEWING THE FUNDAMENTALSCascade, specificity, and inheritanceWorking with relative unitsMastering the box modelPART 2 - MASTERING LAYOUTMaking sense of floatsFlexboxGrid layoutPositioning and stacking contextsResponsive designPART 3 - CSS AT SCALEModular CSSPattern librariesPART 4 - ADVANCED TOPICSBackgrounds, shadows, and blend modesContrast, color, and spacingTypographyTransitionsTransformsAnimations

    Nevertheless, many teachers end up using language patterns that undermine these goals. Do any of these scenarios sound familiar?We want students to take responsibility for their learning, yet we use language that implies teacher ownership.We want to build positive relationships with students, yet we use sarcasm when we get frustrated.We want students to think learning is fun, yet we sometimes make comments that suggest the opposite.We want students to exhibit good behavior because it's the right thing to do, yet we rely on threats and bribes, which implies students don't naturally want to be good.What teachers say to students--when they praise or discipline, give directions or ask questions, and introduce concepts or share stories--affects student learning and behavior. A slight change in intonation can also dramatically change how language feels for students. In What We Say and How We Say It Matter, Mike Anderson digs into the nuances of language in the classroom. This book's many examples will help teachers examine their language habits and intentionally improve their classroom practice so their language matches and supports their goals.

    And I mean all the time. Every day there’s a new cloud-based dating app; a new cloud-based gizmo for your house; a new cloud-based game; or a thousand other new things—all in the cloud.The cloud is everywhere! Everything is in the cloud! What does it mean! Let’s slow down. Take a deep breath. That’s good. Take another. Excellent. This book teaches you all about the cloud. I’ll let you in on a little secret: the cloud is not that hard to understand. It’s not. It’s just that nobody has taken the time to explain to you what the cloud is. They haven’t, have they?Deep down I think this is because they don’t understand the cloud either, but I do. I’ve been a programmer and writer for over 30 years. I’ve been in cloud computing since the very start, and I’m here to help you on your journey to understand the cloud. Consider me your tour guide. I’ll be with you every step of the way, but not in a creepy way.I take my time with this book. I go slow and easy, so you can build up an intuition about what the cloud really is, one idea at a time. When you finish reading, you’ll understand the cloud. When you hear someone say some new cool thing is in the cloud, you’ll understand exactly what they mean. That’s a promise. How do I deliver on that promise? I use lots and lots of pictures. I use lots and lots of examples. We’ll reveal the secret inner-workings of AWS, Netflix, Facebook Messenger, Amazon Kindle, Apple iCloud, Google Maps, Nest and cloud DVRs. You’ll learn by seeing and understanding; no matter if you're a complete beginner, someone who knows a little and wants to learn more, or a programmer looking to change their career to the cloud.The cloud is the future. You don't want to miss out on the future, do you? Read this book and we'll discover it together.I’m excited. This will be fun. Let’s get started!

    Now, in Leading with Focus, he shows administrators, principals, and other education leaders how to apply his model to the work of running schools and districts. In this companion to his previous book, Schmoker offers* An overview of the case for simple, focused school and district leadership--demonstrating its power for vastly improving the work of teachers and leaders.* Examples of real schools and districts that have embraced focused leadership--and the incredible results for student learning.* A practical, flexible, and easy-to-follow implementation guide for ensuring focused leadership in schools and districts.All students deserve to learn in schools where educators eschew distractions and superfluous activities to concentrate on what's most important. To that end, this book is an essential resource for leaders ready to streamline their practice and focus their efforts on radically improving student learning.