We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Braided with that history is the moving story of Powers's beloved son Kevin--spirited, endearing, and gifted--who triumphed even while suffering from schizophrenia until finally he did not, and the story of his courageous surviving son Dean, who is also schizophrenic.A blend of history, biography, memoir, and current affairs ending with a consideration of where we might go from here, this is a thought-provoking look at a dreaded illness that has long been misunderstood.

    Too often, reporters give equal weight to facts and biased opinion, stir up small controversies, and substitute infotainment for real news. Even when they get the facts rights, they often misjudge the context in which they belong. Information is the lifeblood of a healthy democracy. Public opinion and debate suffer when citizens are misinformed about current affairs, as is increasingly the case. Though the failures of today’s communication system cannot be blamed solely on the news media, they are part of the problem, and the best hope for something better. Patterson proposes “knowledge-based journalism” as a corrective. Unless journalists are more deeply informed about the subjects they cover, they will continue to misinterpret them and to be vulnerable to manipulation by their sources. In this book, derived from a multi-year initiative of the Carnegie Corporation and the Knight Foundation, Patterson calls for nothing less than a major overhaul of journalism practice and education. The book speaks not only to journalists but to all who are concerned about the integrity of the information on which America’s democracy depends.

    America’s demand for change in the 2008 election will cause another of our country’s periodic political makeovers. This realignment, like all others before it, will result from the coming of age of a new generation of young Americans—the Millennial Generation—and the full emergence of the Internet-based communications technology that this generation uses so well. Beginning in 2008, almost everything about American politics and government will transform—voting patterns, the fortunes of the two political parties, the issues that engage the nation, and our government and its public policy. Building on the seminal work of previous generational theorists,Morley Winograd and Michael D. Hais demonstrate and describe, for the first time, the two types of realignments—“idealist” and “civic”—that have alternated with one another throughout the nation’s history.  Based on these patterns, Winograd and Hais predict that the next realignment will be very different from the last one that occurred in 1968. “Idealist” realignments, like the one put into motion forty years ago by the Baby Boomer Generation, produce, among other things, a political emphasis on divisive social issues and governmental gridlock. “Civic” realignments, like the one that is coming, and the one produced by the famous GI or “Greatest” Generation in the 1930s, by contrast, tend to produce societal unity, increased attention to and successful resolution of basic economic and foreign policy issues, and institution-building. The authors detail the contours and causes of the country’s five previous political makeovers, before delving deeply into the generational and technological trends that will shape the next.  The book’s final section forecasts the impact of the Millennial Makeover on the elections, issues, and public policies that will characterize America’s politics in the decades ahead. For additional information go to:Millennial Makeover website.

     Do you constantly get anxious about your health and seek reassurance? Have you found yourself analysing every single sensation in your body? Are you spending time on the internet always looking for answers? Do you have heart palpatations that make you think you're having a heart attack? Does that impending heart attack give you a panic attack? Are you still not dead? You can rest assured it's not just you! Philip Martins was once a hypochondriac and has survived, among other things, cancer, motor neurone disease, meningitis, multiple sclerosis and having been bitten by a mosquito once, malaria. In this book he tells you how he got through his years of health anxiety, provides some anecdotes of his crazier times to cheer you up and gives you some tips all in the hope that it can bring a little relief to help you realise you're not alone. If you have health anxiety and are looking for something to relate to then this is the book for you.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    From biblical plagues, to the AIDS crisis, to supergerms of the future, this updated and revised edition of the original covers the whole gamut of diseases that have threatened humanity since its origins.It also includes a new chapter on the history of bioterrorism and the deplorable role it has played and is likely to play in the phenomenal diversity of diseases.

    We are now all too aware of how it is applied, but we know far less about how the idea came to be--and where it may yet go.Until Proven Safe tracks the idea of quarantine around the globe, through time and space, chasing the story from the lazarettos and quarantine islands of Venice--built before communicable diseases were really understood--to the hallways of the CDC, NASA, and the cutting-edge labs and conference rooms where the future technology of quarantine is being developed. The result is a tour of an idea that could not be more urgent or relevant, a book full of stories, people, and insights that is as compelling as it is definitive.

    Or you have persistent pain you and your doctor can't explain. Man or woman, you may be fighting fluctuating hormone levels. Or maybe you snore like a freight train.Anything that narrows the throat and interrupts sleep, particularly breathing problems brought on by sleep position, illness, life changes, or your anatomy, may be key to understanding a host of common health issues. In this groundbreaking book, Dr. Steven Park outlines a simple, rational explanation for what s making you sick, and provides guidance for treatment options that address specific health problems.

    Martin A. Lee traces the dramatic social history of marijuana from its origins to its emergence in the 1960s as a defining force in a culture war that has never ceased. Lee describes how the illicit marijuana subculture overcame government opposition and morphed into a dynamic, multibillion-dollar industry. In 1996, California voters approved Proposition 215, legalizing marijuana for medicinal purposes. Similar laws have followed in more than a dozen other states, but not without antagonistic responses from federal, state, and local law enforcement. Lee, an award-winning investigative journalist, draws attention to underreported scientific breakthroughs that are reshaping the therapeutic landscape. By mining the plant’s rich pharmacopoeia, medical researchers have developed promising treatments for cancer, heart disease, Alzheimer’s, diabetes, chronic pain, and many other conditions that are beyond the reach of conventional cures.Colorful, illuminating, and at times irreverent, this is a fascinating read for recreational users and patients, students and doctors, musicians and accountants, Baby Boomers and their kids, and anyone who has ever wondered about the secret life of this ubiquitous herb. Smoke Signals is the winner of the American Botanical Council's James A. Duke Excellence in Botanical Literature Award for 2012

    

    The year is 2005. A highly infectious, unidentified Ebola-like virus is sweeping through the slums and villages of northern Angola. Within months, more than 200 people have died, medical services have collapsed and aid workers are on the brink of exhaustion. At 23, Peter Apps was just starting out as a foreign correspondent when Reuters sent him into the heart of the outbreak to get the story. In “Before Ebola: Dispatches from a Deadly Outbreak” Apps recalls in vivid, unflinching detail the horrors of life in a hot zone, the compassion of those trying to contain it, and how a terrified young journalist came of age in a time of almost unbearable crisis. Peter Apps is a global defense correspondent for Reuters news, currently dividing his time between London and Washington, D.C. In September 2006, Apps broke his neck in a minibus crash while covering the Sri Lankan civil war, leaving him largely paralyzed from the shoulders down. Cover design by Kristen Radtke.

    Singapore ranks sixth in the world in healthcare outcomes, yet spends proportionally less on healthcare than any other high-income country. This is the first book to set out a comprehensive system-level description of healthcare in Singapore, with a view to understanding what can be learned from its unique system design and development path.The lessons from Singapore will be of interest to those currently planning the future of healthcare in emerging economies, as well as those engaged in the urgent debates on healthcare in the wealthier countries faced with serious long-term challenges in healthcare financing. Policymakers, legislators, public health officials responsible for healthcare systems planning, finance and operations, as well as those working on healthcare issues in universities and think tanks should understand how the Singapore system works to achieve affordable excellence.

    

    Every day, millions of hard-working people struggle to find affordable medical treatment for themselves and their families—unable to pay for prescription drugs and regular checkups, let alone hospital visits. Some of these people end up losing money. Others end up losing something even more valuable: their health or even their lives. In this powerful work of original reportage, Jonathan Cohn travels across the United States—the only country in the developed world that does not guarantee access to medical care as a right of citizenship—to investigate why this crisis is happening and to see firsthand its impact on ordinary Americans.The stories he brings back are tragic and infuriating. In Boston, a heart attack victim becomes a casualty of emergency room overcrowding when she is turned away from the one hospital that could treat her. In South Central L.A., a security guard loses part of his vision when he can't find affordable treatment for his diabetes. In the middle of the prairie heartland, a retired meatpacker sells his house to pay for the medications that keep him and his aging wife alive. And, in a tiny village tucked into the Catskill mountains, a mother of three young children decides against a costly doctor's visit—and lets a deadly cancer go undetected—because her husband's high-tech job no longer provides health insurance.Passionate, illuminating, and often devastating, Sick interweaves these stories with clear-eyed reporting from Washington and takes us inside the medical industry to chronicle the decline of America's health care system—and lays bare the consequences any one of us could suffer if we don't replace it.