Markel writes of the physical and emotional damage caused by the then-heralded wonder drug, and how each man ultimately changed the world in spite of it—or because of it. One became the father of psychoanalysis; the other, of modern surgery. Both men were practicing medicine at the same time in the 1880s: Freud at the Vienna General Hospital, Halsted at New York’s Bellevue Hospital. Markel writes that Freud began to experiment with cocaine as a way of studying its therapeutic uses—as an antidote for the overprescribed morphine, which had made addicts of so many, and as a treatment for depression.  Halsted, an acclaimed surgeon even then, was curious about cocaine’s effectiveness as an anesthetic and injected the drug into his arm to prove his theory. Neither Freud nor Halsted, nor their colleagues, had any idea of the drug’s potential to dominate and endanger their lives. Addiction as a bona fide medical diagnosis didn’t even exist in the elite medical circles they inhabited.  In An Anatomy of Addiction, Markel writes about the life and work of each man, showing how each came to know about cocaine; how Freud found that the drug cured his indigestion, dulled his aches, and relieved his depression. The author writes that Freud, after a few months of taking the magical drug, published a treatise on it, Über Coca, in which he described his “most gorgeous excitement.” The paper marked a major shift in Freud’s work: he turned from studying the anatomy of the brain to exploring the human psyche.  Halsted, one of the most revered of American surgeons, became the head of surgery at the newly built Johns Hopkins Hospital and then professor of surgery, the hospital’s most exalted position, committing himself repeatedly to Butler Hospital, an insane asylum, to withdraw from his out-of control cocaine use.  Halsted invented modern surgery as we know it today: devising new ways to safely invade the body in search of cures and pioneering modern surgical techniques that controlled bleeding and promoted healing. He insisted on thorough hand washing, on scrub-downs and whites for doctors and nurses, on sterility in the operating room—even inventing the surgical glove, which he designed and had the Goodyear Rubber Company make for him—accomplishing all of this as he struggled to conquer his unyielding desire for cocaine.  An Anatomy of Addiction tells the tragic and heroic story of each man, accidentally struck down in his prime by an insidious malady: tragic because of the time, relationships, and health cocaine forced each to squander; heroic in the intense battle each man waged to overcome his affliction as he conquered his own world with his visionary healing gifts. Here is the full story, long overlooked, told in its rich historical context.

    Bell suggests that the answer is yes."Everyone interested in anorexia nervosa . . . should skim this book or study it. It will make you realize how dependent upon culture the definition of disease is. I will never look at an anorexic patient in the same way again."—Howard Spiro, M.D., Gastroenterology"[This] book is a first-class social history and is well-documented both in its historical and scientific portions."—Vern L. Bullough, American Historical Review"A significant contribution to revisionist history, which re-examines events in light of feminist thought. . . . Bell is particularly skillful in describing behavior within its time and culture, which would be bizarre by today's norms, without reducing it to the pathological."—Mary Lassance Parthun, Toronto Globe and Mail"Bell is both enlightened and convincing. His book is impressively researched, easy to read, and utterly fascinating."—Sheila MacLeod, New Statesman

    Levitin shifts his keen insights from your brain on music to your brain in a sea of details.The information age is drowning us with an unprecedented deluge of data. At the same time, we’re expected to make more—and faster—decisions about our lives than ever before. No wonder, then, that the average American reports frequently losing car keys or reading glasses, missing appointments, and feeling worn out by the effort required just to keep up.But somehow some people become quite accomplished at managing information flow. In The Organized Mind, Daniel J. Levitin, PhD, uses the latest brain science to demonstrate how those people excel—and how readers can use their methods to regain a sense of mastery over the way they organize their homes, workplaces, and time.With lively, entertaining chapters on everything from the kitchen junk drawer to health care to executive office workflow, Levitin reveals how new research into the cognitive neuroscience of attention and memory can be applied to the challenges of our daily lives. This Is Your Brain on Music showed how to better play and appreciate music through an understanding of how the brain works. The Organized Mind shows how to navigate the churning flood of information in the twenty-first century with the same neuroscientific perspective.

    Now, in The Upside of Irrationality, he exposes the surprising negative and positive effects irrationality can have on our lives. Focusing on our behaviors at work and in relationships, he offers new insights and eye-opening truths about what really motivates us on the job, how one unwise action can become a long-term habit, how we learn to love the ones we're with, and more. Drawing on the same experimental methods that made Predictably Irrational one of the most talked-about bestsellers of the past few years, Ariely uses data from his own original and entertaining experiments to draw arresting conclusions about how—and why—we behave the way we do. From our office attitudes, to our romantic relationships, to our search for purpose in life, Ariely explains how to break through our negative patterns of thought and behavior to make better decisions. The Upside of Irrationality will change the way we see ourselves at work and at home—and cast our irrational behaviors in a more nuanced light.

    He also crystallized one of the most important debates of our time: As we enjoy the Net’s bounties, are we sacrificing our ability to read and think deeply?Now, Carr expands his argument into the most compelling exploration of the Internet’s intellectual and cultural consequences yet published. As he describes how human thought has been shaped through the centuries by “tools of the mind”—from the alphabet to maps, to the printing press, the clock, and the computer—Carr interweaves a fascinating account of recent discoveries in neuroscience by such pioneers as Michael Merzenich and Eric Kandel. Our brains, the historical and scientific evidence reveals, change in response to our experiences. The technologies we use to find, store, and share information can literally reroute our neural pathways.Building on the insights of thinkers from Plato to McLuhan, Carr makes a convincing case that every information technology carries an intellectual ethic—a set of assumptions about the nature of knowledge and intelligence. He explains how the printed book served to focus our attention, promoting deep and creative thought. In stark contrast, the Internet encourages the rapid, distracted sampling of small bits of information from many sources. Its ethic is that of the industrialist, an ethic of speed and efficiency, of optimized production and consumption—and now the Net is remaking us in its own image. We are becoming ever more adept at scanning and skimming, but what we are losing is our capacity for concentration, contemplation, and reflection.Part intellectual history, part popular science, and part cultural criticism, The Shallows sparkles with memorable vignettes—Friedrich Nietzsche wrestling with a typewriter, Sigmund Freud dissecting the brains of sea creatures, Nathaniel Hawthorne contemplating the thunderous approach of a steam locomotive—even as it plumbs profound questions about the state of our modern psyche. This is a book that will forever alter the way we think about media and our minds.

    Their visionary answers flow from the frontiers of psychology, philosophy, economics, physics, sociology, and more. Surprising and enlightening, these insights will revolutionize the way you think about yourself and the world.Contributors include:Daniel Kahneman on the “focusing illusion”Jonah Lehrer on controlling attentionRichard Dawkins on experimentationAubrey De Grey on conquering our fear of the unknownMartin Seligman on the ingredients of well-beingNicholas Carr on managing “cognitive load”Steven Pinker on win-win negotiatingDaniel Goleman on understanding our connection to the natural worldMatt Ridley on tapping collective intelligenceLisa Randall on effective theorizingBrian Eno on “ecological vision”J. Craig Venter on the multiple possible origins of life  Helen Fisher on temperamentSam Harris on the flow of thoughtLawrence Krauss on living with uncertainty

     For his groundbreaking sexual research, Alfred Kinsey and his team interviewed 18,000 people, relying on them to honestly report their most intimate experiences. Using the Internet, the neuroscientists Ogas and Gaddam quietly observed the raw sexual behaviors of half a billion people. By combining their observations with neuroscience and animal research, these two young neuroscientists finally answer the long-disputed question: what do people really like? Ogas and Gaddam's findings are transforming the way scientists and therapists think about sexual desire. In their startling book, Ogas and Gaddam analyze a "billion wicked thoughts" on the Internet: a billion Web searches, a million individual search histories, a million erotic stories, a half-million erotic videos, a million Web sites, millions of online personal ads, and many other enormous sources of sexual data in order to understand the true differences between male and female desires, including: ?Men and women have hardwired sexual cues analogous to our hardwired tastes-there are sexual versions of sweet, sour, salty, savory, and bitter. But men and women are wired with different sets of cues. ?The male sexual brain resembles a reckless hunter, while the female sexual brain resembles a cautious detective agency. ?Men form their sexual interests during adolescence and rarely change. Women's sexual interests are plastic and change frequently. ?The male sexual brain is an "or gate": A single stimulus can arouse it. The female sexual brain is an "and gate": It requires many simultaneous stimuli to arouse it. ?When it comes to sexual arousal, men prefer overweight women to underweight women, and a significant number of men seek out erotic images of women in their 40s, 50s, and 60s. ?Women enjoy writing and sharing erotic stories with other women. The fastest growing genre of erotic stories for women are stories about two heterosexual men having sex. ?Though the male sexual brain is much more different from the female sexual brain than is commonly believed, the sexual brain of gay men is virtually identical to that of straight men. Featuring cutting-edge, jaw-dropping science, this wildly entertaining and controversial book helps readers understand their partner's sexual desires with a depth of knowledge unavailable from any other source. Its fascinating and occasionally disturbing findings will rock our modern understanding of sexuality, just as Kinsey's reports did sixty years ago.

    Our eyes play tricks on us; our stories change in the retelling; and most of us are fairly sure we’re way above average. In Why We Make Mistakes, journalist Joseph T. Hallinan sets out to explore the science of human error—how we think, see, remember, and forget, and how this sets us up for wholly irresistible mistakes.In his quest to understand our imperfections, Hallinan delves into psychology, neuroscience, and economics, with forays into aviation, consumer behavior, geography, football, stock picking, and more. He discovers that some of the same qualities that make us efficient also make us error prone. Why We Make Mistakes is enlivened by real-life stories--of weathermen whose predictions are uncannily accurate and a witness who sent an innocent man to jail--and offers valuable advice, such as how to remember where you’ve hidden something important. He explains why multitasking is a bad idea, why men make errors women don’t. This book will open your eyes to the reasons behind your mistakes and have you vowing to do better the next time.

    Whether you’re deciding which smart phone to purchase or which politician to believe, you think you are a rational being whose every decision is based on cool, detached logic, but here’s the truth: You are not so smart. You’re just as deluded as the rest of us--but that’s okay, because being deluded is part of being human. Growing out of David McRaney’s popular blog, You Are Not So Smart reveals that every decision we make, every thought we contemplate, and every emotion we feel comes with a story we tell ourselves to explain them, but often these stories aren’t true. Each short chapter--covering topics such as Learned Helplessness, Selling Out, and the Illusion of Transparency--is like a psychology course with all the boring parts taken out.Bringing together popular science and psychology with humor and wit, You Are Not So Smart is a celebration of our irrational, thoroughly human behavior.

    Francis Bacon held some of the highest public offices in the land and in his spare time studied natural philosophy and a wide variety of other subjects. His systematic classification of all branches of knowledge became the basis for all later constructions, and his Essays are unsurpassed in their observations on society and human behavior. This extensive anthology includes the major English literary works on which his reputation rests: The Advancement of Learning, The Essays (1625, as well as the earliest version of 1597), and the posthumously published Utopian fable The New Atlantis (1626). In addition it reprints other works which illustrate Bacon's abilities in politics, law, theology, and poetry. A special feature of the edition is its extensive annotation which identifies Bacon's sources and allusions, and elucidates his vocabulary.

    Vividly bringing to life the latest scientific research in psychology, cognitive neuroscience, philosophy, and behavioral economics, Gilbert reveals what scientists have discovered about the uniquely human ability to imagine the future, and about our capacity to predict how much we will like it when we get there. With penetrating insight and sparkling prose, Gilbert explains why we seem to know so little about the hearts and minds of the people we are about to become.

    Why do some places--the concourse of Grand Central Terminal or a small farm or even the corner of a skyscraper--affect us so mysteriously and yet so forcefully? What tiny changes in our everyday environments can radically alter the quality of our daily lives? The Experience of Place offers an innovative and delightfully readable proposal for new ways of planning, building, and managing our most immediate and overlooked surroundings.

    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

    Our brains, therefore, are designed not just to hunt and gather, but also to help us get ahead socially, often via deception and self-deception. But while we may be self-interested schemers, we benefit by pretending otherwise. The less we know about our own ugly motives, the better - and thus we don't like to talk or even think about the extent of our selfishness. This is "the elephant in the brain." Such an introspective taboo makes it hard for us to think clearly about our nature and the explanations for our behavior. The aim of this book, then, is to confront our hidden motives directly - to track down the darker, unexamined corners of our psyches and blast them with floodlights. Then, once everything is clearly visible, we can work to better understand ourselves: Why do we laugh? Why are artists sexy? Why do we brag about travel? Why do we prefer to speak rather than listen?Our unconscious motives drive more than just our private behavior; they also infect our venerated social institutions such as Art, School, Charity, Medicine, Politics, and Religion. In fact, these institutions are in many ways designed to accommodate our hidden motives, to serve covert agendas alongside their "official" ones. The existence of big hidden motives can upend the usual political debates, leading one to question the legitimacy of these social institutions, and of standard policies designed to favor or discourage them. You won't see yourself - or the world - the same after confronting the elephant in the brain.

    Crawford explored the ethical and practical importance of manual competence, as expressed through mastery of our physical environment. In his brilliant follow-up, The World Beyond Your Head, Crawford investigates the challenge of mastering one's own mind.We often complain about our fractured mental lives and feel beset by outside forces that destroy our focus and disrupt our peace of mind. Any defense against this, Crawford argues, requires that we reckon with the way attention sculpts the self.Crawford investigates the intense focus of ice hockey players and short-order chefs, the quasi-autistic behavior of gambling addicts, the familiar hassles of daily life, and the deep, slow craft of building pipe organs. He shows that our current crisis of attention is only superficially the result of digital technology, and becomes more comprehensible when understood as the coming to fruition of certain assumptions at the root of Western culture that are profoundly at odds with human nature.The World Beyond Your Head makes sense of an astonishing array of common experience, from the frustrations of airport security to the rise of the hipster. With implications for the way we raise our children, the design of public spaces, and democracy itself, this is a book of urgent relevance to contemporary life.