More than 200 million years ago, geological forces split apart the continents. Isolated from each other, the two halves of the world developed radically different suites of plants and animals. When Christopher Columbus set foot in the Americas, he ended that separation at a stroke. Driven by the economic goal of establishing trade with China, he accidentally set off an ecological convulsion as European vessels carried thousands of species to new homes across the oceans. The Columbian Exchange, as researchers call it, is the reason there are tomatoes in Italy, oranges in Florida, chocolates in Switzerland, and chili peppers in Thailand. More important, creatures the colonists knew nothing about hitched along for the ride. Earthworms, mosquitoes, and cockroaches; honeybees, dandelions, and African grasses; bacteria, fungi, and viruses; rats of every description—all of them rushed like eager tourists into lands that had never seen their like before, changing lives and landscapes across the planet. Eight decades after Columbus, a Spaniard named Legazpi succeeded where Columbus had failed. He sailed west to establish continual trade with China, then the richest, most powerful country in the world. In Manila, a city Legazpi founded, silver from the Americas, mined by African and Indian slaves, was sold to Asians in return for silk for Europeans. It was the first time that goods and people from every corner of the globe were connected in a single worldwide exchange. Much as Columbus created a new world biologically, Legazpi and the Spanish empire he served created a new world economically.As Charles C. Mann shows, the Columbian Exchange underlies much of subsequent human history. Presenting the latest research by ecologists, anthropologists, archaeologists, and historians, Mann shows how the creation of this worldwide network of ecological and economic exchange fostered the rise of Europe, devastated imperial China, convulsed Africa, and for two centuries made Mexico City—where Asia, Europe, and the new frontier of the Americas dynamically interacted—the center of the world. In such encounters, he uncovers the germ of today’s fiercest political disputes, from immigration to trade policy to culture wars.In 1493, Charles Mann gives us an eye-opening scientific interpretation of our past, unequaled in its authority and fascination

    Examining a series of El Niño-induced droughts and the famines that they spawned around the globe in the last third of the nineteenth century, Mike Davis discloses the intimate, baleful relationship between imperial arrogance and natural incident that combined to produce some of the worst tragedies in human history and to sow the seeds of underdevelopment in what later became known as the Third World.

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    But Pankaj Mishra shows that it was otherwise in this stereotype-shattering book. His enthralling group portrait of like minds scattered across a vast continent makes clear that modern Asia’s revolt against the West is not the one led by faith-fired terrorists and thwarted peasants but one with deep roots in the work of thinkers who devised a view of life that was neither modern nor antimodern, neither colonialist nor anticolonialist. In broad, deep, dramatic chapters, Mishra tells the stories of these figures, unpacks their philosophies, and reveals their shared goal of a greater Asia.       Right now, when the emergence of a greater Asia seems possible as at no previous time in history, From The Ruins Of Empire is as necessary as it is timely—a book essential to our understanding of the world and our place in it.

    People knew the basics: men and women had sex, and sometimes babies followed. But beyond that the origins of life were a colossal mystery. The Seeds of Life is the remarkable and rollicking story of how a series of blundering geniuses and brilliant amateurs struggled for two centuries to discover where, exactly, babies come from. Taking a page from investigative thrillers, acclaimed science writer Edward Dolnick looks to these early scientists as if they were detectives hot on the trail of a bedeviling and urgent mystery. These strange searchers included an Italian surgeon using shark teeth to prove that female reproductive organs were not 'failed' male genitalia, and a Catholic priest who designed ingenious miniature pants to prove that frogs required semen to fertilize their eggs. A witty and rousing history of science, The Seeds of Life presents our greatest scientists struggling-against their perceptions, their religious beliefs, and their deep-seated prejudices-to uncover how and where we come from.

    By 15,000 BC, humans had migratedfrom northeastern Asia across the frozen Beringland bridge to the Americas. When the world warmed up and the last Ice Age came to an end,the Bering Strait refilled with water, dividing America from Eurasia. This division—with two great populations on Earth, each unaware of theater—continued until Christopher Columbus voyaged to the New World in the fifteenth century.The Great Divide compares the development of human kind in the Old World and the New between 15,000 BC and AD 1500. Watson identifies three major differences between the two worlds—climate, domesticable mammals, and hallucinogenic plants—that combined to produce very different trajectories of civilization in the two hemispheres. Combining the most up-to-date knowledge in archaeology, anthropology, geology, meteorology, cosmology, and mythology, this unprecedented, masterful study offers uniquely revealing insight into what it means to be human.

    This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences," leads the reader through unexplored jungles and uncharted aspects of mind to the heart of knowledge.In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.

    Aspirin, the world's most widely used drug, is based on compounds originally extracted from the bark of a willow tree, and more than a quarter of medicines found on pharmacy shelves contain plant compounds. Now Western medicine, faced with health crises such as AIDS, Alzheimer's disease, and cancer, has begun to look to the healing plants used by indigenous peoples to develop powerful new medicines. Nowhere is the search more promising than in the Amazon, the world's largest tropical forest, home to a quarter of all botanical species on this planet—as well as hundreds of Indian tribes whose medicinal plants have never been studied by Western scientists. In Tales of a Shaman's Apprentice, ethnobotanist Mark J. Plotkin recounts his travels and studies with some of the most powerful Amazonian shamans, who taught him the plant lore their tribes have spent thousands of years gleaning from the rain forest.For more than a decade, Dr. Plotkin has raced against time to harvest and record new plants before the rain forests' fragile ecosystems succumb to overdevelopment—and before the Indians abandon their own culture and learning for the seductive appeal of Western material culture. Tales of a Shaman's Apprentice relates nine of the author's quests, taking the reader along on a wild odyssey as he participates in healing rituals; discovers the secret of curare, the lethal arrow poison that kills in minutes; tries the hallucinogenic snuff epena that enables the Indians to speak with their spirit world; and earns the respect and fellowship of the mysterious shamans as he proves that he shares both their endurance and their reverence for the rain forest. Mark Plotkin combines the Darwinian spirit of the great writer-explorers of the nineteenth century—curious, discursive, and rigorously scientific—with a very modern concern for the erosion of our environment and the vanishing culture of native peoples.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    She also explores the ambiguous moral implications inherent in this kind of warfare: Are these nefarious forms of weaponry ingenious or cowardly? Admirable or reprehensible?

    In 1971 he was discovered on the remote Galapagos island of Pinta, from which tortoises had supposedly been exterminated by greedy whalers and seal hunters. He has been at the Charles Darwin Research Station on Santa Cruz island ever since, on the off-chance that scientific ingenuity will conjure up a way of reproducing him and resurrecting his species. Meanwhile a million tourists and dozens of baffled scientists have looked on as the celebrity reptile shows not a jot of interest in the female company provided. Today, Lonesome George has come to embody the mystery, complexity and fragility of the unique Galapagos archipelago. His story echoes the challenges of conservation worldwide; it is a story of Darwin, sexual dysfunction, adventure on the high seas, cloning, DNA fingerprinting and eco-tourism.

    In Polynesia we set sail with navigators whose ancestors settled the Pacific ten centuries before Christ. In the Amazon we meet the descendants of a true lost civilization, the Peoples of the Anaconda. In the Andes we discover that the earth really is alive, while in Australia we experience Dreamtime, the all-embracing philosophy of the first humans to walk out of Africa. We then travel to Nepal, where we encounter a wisdom hero, a Bodhisattva, who emerges from forty-five years of Buddhist retreat and solitude. And finally we settle in Borneo, where the last rain forest nomads struggle to survive. Understanding the lessons of this journey will be our mission for the next century. For at risk is the human legacy--a vast archive of knowledge and expertise, a catalog of the imagination. Rediscovering a new appreciation for the diversity of the human spirit, as expressed by culture, is among the central challenges of our time.

    Its presence in nature was dismissed as a desperate response to starvation or other life-threatening circumstances, and few spent time studying it. A taboo subject in our culture, the behavior was portrayed mostly through horror movies or tabloids sensationalizing the crimes of real-life flesh-eaters. But the true nature of cannibalism--the role it plays in evolution as well as human history--is even more intriguing (and more normal) than the misconceptions we've come to accept as fact. In Cannibalism: A Perfectly Natural History, zoologist Bill Schutt sets the record straight, debunking common myths and investigating our new understanding of cannibalism's role in biology, anthropology, and history in the most fascinating account yet written on this complex topic. Schutt takes readers from Arizona's Chiricahua Mountains, where he wades through ponds full of tadpoles devouring their siblings, to the Sierra Nevadas, where he joins researchers who are shedding new light on what happened to the Donner Party--the most infamous episode of cannibalism in American history. He even meets with an expert on the preparation and consumption of human placenta (and, yes, it goes well with Chianti). Bringing together the latest cutting-edge science, Schutt answers questions such as why some amphibians consume their mother's skin; why certain insects bite the heads off their partners after sex; why, up until the end of the twentieth century, Europeans regularly ate human body parts as medical curatives; and how cannibalism might be linked to the extinction of the Neanderthals. He takes us into the future as well, investigating whether, as climate change causes famine, disease, and overcrowding, we may see more outbreaks of cannibalism in many more species--including our own.Cannibalism places a perfectly natural occurrence into a vital new context and invites us to explore why it both enthralls and repels us.

    Here and there, we can supplement these meager scraps by the use of biochemical markers or geochemical signatures that add useful information, but, even with such additional help, our reconstructions and our models of descent are often tentative. For the fossil record is, as we have seen, as biased as it is incomplete. But fragmentary, selective, and biased though it is, the fossil record, with all its imperfections, is still a treasure. Though whole chapters are missing, many pages lost, and the earliest pages so damaged as to be, as yet, virtually unreadable, this--the greatest biography of all--is one in whose closing pages we find ourselves.--from OriginsIn Origins, Frank H. T. Rhodes explores the origin and evolution of living things, the changing environments in which they have developed, and the challenges we now face on an increasingly crowded and polluted planet. Rhodes argues that the future well-being of our burgeoning population depends in no small part on our understanding of life's past, its long and slow development, and its intricate interdependencies.Rhodes's accessible and extensively illustrated treatment of the origins narrative describes the nature of the search for prehistoric life, the significance of geologic time, the origin of life, the emergence and spread of flora and fauna, the evolution of primates, and the emergence of modern humans.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.