That is until 1904, when the disease broke out in a household in Oyster Bay, Long Island. Authorities suspected the family cook, Mary Mallon, of being a carrier. But before she could be tested, the woman, soon to be known as Typhoid Mary, had disappeared. Over the course of the next three years, Mary worked at several residences, spreading her pestilence as she went. In 1907, she was traced to a home on Park Avenue, and taken into custody. Institutionalized at Riverside Hospital for three years, she was released only when she promised never to work as a cook again. She promptly disappeared.For the next five years Mary worked in homes and institutions in and around New York, often under assumed names. In February 1915, a devastating outbreak of typhoid at the Sloane Hospital for Women was traced to her. She was finally apprehended and reinstitutionalized at Riverside Hospital, where she would remain for the rest of her life.Typhoid Mary is the story of her infamous life. Anthony Bourdain reveals the seedier side of the early 1900s, and writes with his renowned panache about life in the kitchen, uncovering the horrifying conditions that allowed the deadly spread of typhoid over a decade. Typhoid Mary is a true feast for history lovers and Bourdain lovers alike.

    Herzog’s groundbreaking research on animal rights activists, cockfighters, professional dog-show handlers, veterinary students, and biomedical researchers. Blending anthropology, behavioral economics, evolutionary psychology, and philosophy, Herzog carefully crafts a seamless narrative enriched with real-life anecdotes, scientific research, and his own sense of moral ambivalence.Alternately poignant, challenging, and laugh-out-loud funny, this enlightening and provocative book will forever change the way we look at our relationships with other creatures and, ultimately, how we see ourselves.

    In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. http://us.macmillan.com/missingmicrob...

    And there is no more accomplished and accessible guide than renowned neuroscientist David Eagleman to help us understand the nature and changing texture of that fabric. With his hallmark clarity and enthusiasm he reveals the myriad ways that the brain absorbs experience: developing, redeploying, organizing, and arranging the data it receives from the body's own absorption of external stimuli, which enables us to gain the skills, the facilities, and the practices that make us who we are. Eagleman covers decades of the most important research into the functioning of the brain and presents new discoveries from his own research as well: about the nature of synesthesia, about dreaming, and about wearable devices that are revolutionizing how we think about the five human senses. Finally, Livewired is as deeply informative as it is accessible and brilliantly engaging.

    Astrophysicist Adam Frank traces the question of alien life and intelligence from the ancient Greeks to the leading thinkers of our own time, and shows how we as a civilization can only hope to survive climate change if we recognize what science has recently discovered: that we are just one of ten billion trillion planets in the Universe, and it’s highly likely that many of those planets hosted technologically advanced alien civilizations. What’s more, each of those civilizations must have faced the same challenge of civilization-driven climate change.Written with great clarity and conviction, Light of the Stars builds on the inspiring work of pioneering scientists such as Frank Drake and Carl Sagan, whose work at the dawn of the space age began building the new science of astrobiology; Jack James, the Texas-born engineer who drove NASA’s first planetary missions to success; Vladimir Vernadsky, the Russian geochemist who first envisioned the Earth’s biosphere; and James Lovelock and Lynn Margulis, who invented Gaia theory. Frank recounts the perilous journey NASA undertook across millions of miles of deep space to get its probes to Venus and Mars, yielding our first view of the cosmic laws of planets and climate that changed our understanding of our place in the universe.Thrilling science at the grandest of scales, Light of the Stars explores what may be the largest question of all: What can the likely presence of life on other worlds tell us about our own fate?

    Rather, they recruited an elite group of young women who, with only pencil, paper, and mathematical prowess, transformed rocket design, helped bring about the first American satellites, and made the exploration of the solar system possible. For the first time, Rise of the Rocket Girls tells the stories of these women--known as "human computers"--who broke the boundaries of both gender and science. Based on extensive research and interviews with all the living members of the team, Rise of the Rocket Girls offers a unique perspective on the role of women in science: both where we've been, and the far reaches of space to which we're heading.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    Ballet dancers and rock musicians, professors and thieves-"anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care-ended up here. So did Victoria Sweet, who came for two months and stayed for twenty years. Laguna Honda, lower tech but human paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished. Gradually, the place transformed the way she understood her work. Alongside the modern view of the body as a machine to be fixed, her extraordinary patients evoked an older idea, of the body as a garden to be tended. God's Hotel tells their story and the story of the hospital itself, which, as efficiency experts, politicians, and architects descended, determined to turn it into a modern "health care facility," revealed its own surprising truths about the essence, cost, and value of caring for body and soul.

    This has always been the case, no matter how often that certainty has failed. Though no generation believes there’s nothing left to learn, every generation unconsciously assumes that what has already been defined and accepted is (probably) pretty close to how reality will be viewed in perpetuity. And then, of course, time passes. Ideas shift. Opinions invert. What once seemed reasonable eventually becomes absurd, replaced by modern perspectives that feel even more irrefutable and secure—until, of course, they don’t.But What If We’re Wrong? visualizes the contemporary world as it will appear to those who'll perceive it as the distant past. Chuck Klosterman asks questions that are profound in their simplicity: How certain are we about our understanding of gravity? How certain are we about our understanding of time? What will be the defining memory of rock music, five hundred years from today? How seriously should we view the content of our dreams? How seriously should we view the content of television? Are all sports destined for extinction? Is it possible that the greatest artist of our era is currently unknown (or—weirder still—widely known, but entirely disrespected)? Is it possible that we “overrate” democracy? And perhaps most disturbing, is it possible that we’ve reached the end of knowledge?Kinetically slingshotting through a broad spectrum of objective and subjective problems, But What If We’re Wrong? is built on interviews with a variety of creative thinkers—George Saunders, David Byrne, Jonathan Lethem, Kathryn Schulz, Neil deGrasse Tyson, Brian Greene, Junot Díaz, Amanda Petrusich, Ryan Adams, Nick Bostrom, Dan Carlin, and Richard Linklater, among others—interwoven with the type of high-wire humor and nontraditional analysis only Klosterman would dare to attempt. It’s a seemingly impossible achievement: a book about the things we cannot know, explained as if we did. It’s about how we live now, once “now” has become “then.”

    As Tom Standage relates with authority and charm, six of them have had a surprisingly pervasive influence on the course of history, becoming the defining drink during a pivotal historical period. A History of the World in 6 Glasses tells the story of humanity from the Stone Age to the 21st century through the lens of beer, wine, spirits, coffee, tea, and cola. Beer was first made in the Fertile Crescent and by 3000 B.C.E. was so important to Mesopotamia and Egypt that it was used to pay wages. In ancient Greece wine became the main export of her vast seaborne trade, helping spread Greek culture abroad. Spirits such as brandy and rum fueled the Age of Exploration, fortifying seamen on long voyages and oiling the pernicious slave trade. Although coffee originated in the Arab world, it stoked revolutionary thought in Europe during the Age of Reason, when coffeehouses became centers of intellectual exchange. And hundreds of years after the Chinese began drinking tea, it became especially popular in Britain, with far-reaching effects on British foreign policy. Finally, though carbonated drinks were invented in 18th-century Europe they became a 20th-century phenomenon, and Coca-Cola in particular is the leading symbol of globalization.For Tom Standage, each drink is a kind of technology, a catalyst for advancing culture by which he demonstrates the intricate interplay of different civilizations. You may never look at your favorite drink the same way again.

    Americans eat more bananas than apples and oranges combined. In others parts of the world, bananas are what keep millions of people alive. But for all its ubiquity, the banana is surprisingly mysterious; nobody knows how bananas evolved or exactly where they originated. Rich cultural lore surrounds the fruit: In ancient translations of the Bible, the 'apple' consumed by Eve is actually a banana (it makes sense, doesn't it?). Entire Central American nations have been said to rise and fall over the banana. But the biggest mystery about the banana today is whether it will survive. A seedless fruit with a unique reproductive system, every banana is a genetic duplicate of the next, and therefore susceptible to the same blights. Today's yellow banana, the Cavendish, is increasingly threatened by such a blight -- and there's no cure in sight. Banana combines a pop-science journey around the globe, a fascinating tale of an iconic American business enterprise, and a look into the alternately tragic and hilarious banana subculture (one does exist) -- ultimately taking us to the high-tech labs where new bananas are literally being built in test tubes, in a race to save the world's most beloved fruit.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    Although there are more than thirty thousand species of fish—more than all mammals, birds, reptiles, and amphibians combined—we rarely consider how individual fishes think, feel, and behave. Balcombe upends our assumptions about fishes, portraying them not as unfeeling, dead-eyed feeding machines but as sentient, aware, social, and even Machiavellian—in other words, much like us. What a Fish Knows draws on the latest science to present a fresh look at these remarkable creatures in all their breathtaking diversity and beauty. Fishes conduct elaborate courtship rituals and develop lifelong bonds with shoalmates. They also plan, hunt cooperatively, use tools, curry favor, deceive one another, and punish wrongdoers. We may imagine that fishes lead simple, fleeting lives—a mode of existence that boils down to a place on the food chain, rote spawning, and lots of aimless swimming. But, as Balcombe demonstrates, the truth is far richer and more complex, worthy of the grandest social novel. Highlighting breakthrough discoveries from fish enthusiasts and scientists around the world and pondering his own encounters with fishes, Balcombe examines the fascinating means by which fishes gain knowledge of the places they inhabit, from shallow tide pools to the deepest reaches of the ocean. Teeming with insights and exciting discoveries, What a Fish Knows offers a thoughtful appraisal of our relationships with fishes and inspires us to take a more enlightened view of the planet’s increasingly imperiled marine life. What a Fish Knows will forever change how we see our aquatic cousins—the pet goldfish included.

    And before there were fish in the sea, there were cephalopods - the ancestors of modern squid and Earth’s first truly substantial animals. Cephalopods became the first creatures to rise from the seafloor, essentially inventing the act of swimming. With dozens of tentacles and formidable shells, they presided over an undersea empire for millions of years. But when fish evolved jaws, the ocean’s former top predator became its most delicious snack. Cephalopods had to step up their game. Many species streamlined their shells and added defensive spines, but these enhancements only provided a brief advantage. Some cephalopods then abandoned the shell entirely, which opened the gates to a flood of evolutionary innovations: masterful camouflage, fin-supplemented jet propulsion, perhaps even dolphin-like intelligence. Squid Empire is an epic adventure spanning hundreds of millions of years, from the marine life of the primordial ocean to the calamari on tonight’s menu. Anyone who enjoys the undersea world—along with all those obsessed with things prehistoric—will be interested in the sometimes enormous, often bizarre creatures that ruled the seas long before the first dinosaurs.

    Set in Edwardian London and on the stormy coasts of Cornwall, Cape Cod, and Nova Scotia, Thunderstruck evokes the dynamism of those years when great shipping companies competed to build the biggest, fastest ocean liners, scientific advances dazzled the public with visions of a world transformed, and the rich outdid one another with ostentatious displays of wealth. Against this background, Marconi races against incredible odds and relentless skepticism to perfect his invention: the wireless, a prime catalyst for the emergence of the world we know today. Meanwhile, Crippen, “the kindest of men,” nearly commits the perfect crime. With his superb narrative skills, Erik Larson guides these parallel narratives toward a relentlessly suspenseful meeting on the waters of the North Atlantic. Along the way, he tells of a sad and tragic love affair that was described on the front pages of newspapers around the world, a chief inspector who found himself strangely sympathetic to the killer and his lover, and a driven and compelling inventor who transformed the way we communicate. Thunderstruck presents a vibrant portrait of an era of séances, science, and fog, inhabited by inventors, magicians, and Scotland Yard detectives, all presided over by the amiable and fun-loving Edward VII as the world slid inevitably toward the first great war of the twentieth century. Gripping from the first page, and rich with fascinating detail about the time, the people, and the new inventions that connect and divide us, Thunderstruck is splendid narrative history from a master of the form.