Leptin is your body’s natural weight-loss mechanism: it curbs your appetite, jump-starts your metabolism, and when working properly makes you literally fat resistant—you will lose weight effortlessly and efficiently and never gain those pounds back.If you’re struggling to lose weight, chances are you are “leptin resistant”—your body no longer responds to leptin, making it impossible for you to slim down. The Fat Resistance Diet is the first and only eating plan designed specifically to combat leptin resistance and reprogram your body to start melting away the pounds. Using a breakthrough combination of anti-inflammatory and hormone-balancing foods, the three-phase regimen delivers:A loss of six to ten pounds in the first two weeks.A loss of at least two pounds a week thereafter. Fun, flavorful meals that make sticking with the plan a breeze.An easy maintenance program that keeps you fat resistant for life.With over 100 delicious recipes designed for maximum satisfaction and eating pleasure, the Fat Resistance Diet is the only diet you’ll ever need—a brand new way to eat that will transform your body into a lean, fat-fighting machine.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    It focuses on the tumultuous lives of two Afghan women and how their lives cross each other, spanning from the 1960s to 2003. The book was released on May 22, 2007, and received favorable prepublication reviews from Kirkus, Publishers Weekly, Library Journal, and Booklist, as well as reaching #2 on Amazon.com's bestseller list before its release. Time magazine's Lev Grossman placed it at number three in the Top 10 Fiction Books of 2007, and praised it as a "dense, rich, pressure-packed guide to enduring the unendurable." Jonathan Yardley said in the Washington Post "Book World": "Just in case you're wondering whether Khaled Hosseini's A Thousand Splendid Suns is as good as The Kite Runner, here's the answer: No. It's better."

    Some mammoths were smaller than children. Owls are the dumbest birds in the world. Very few people with Tourette's syndrome swear. You can't get a six-pack from doing sit-ups. King Arthur's sword wasn't called Excalibur. Milk doesn't make your bones strong. There's no bones in your fingers. The Bible states that humans can't become angels. Humans have more than two nostrils. It's impossible to slide down a bannister. At a wedding, the bride doesn't walk down the aisle. Ties were invented for war, not fashion. Most Disney classics made almost no money. Slavery has only been illegal in the UK since 2010. George Washington wasn't the first American President. Velcro doesn’t exist. Nobody knows why we sleep.

    

     “One Hell of a War” is a fascinating blend of first-hand accounts and the strategic decisions that led to them based on the history of the 317th Infantry Regiment from its initial activation in World War II through the end of the war. This book has all the elements everyone loved in “Band of Brothers” with the added integration of the strategic leadership decisions of Patton, Bradley and Eisenhower. Most interestingly, it contains well written and thought-provoking excerpts of the late Colonel James Hayes, who served with the regiment during its entire wartime service. The history books do not say a great deal about the 317th Infantry Regiment of the 80th Infantry Division in WWII. However, it was a regiment that accomplished rather startling results: first bridgehead across the Moselle, cleared out La Grande Couronne de Nancy, participated in the capture of Metz -- the first time in history that the fort had ever fallen to an assault, and, of course, participated in the Battle of the Bulge as one of the first regiments to arrive in the area after the German assault had broken the line. It suffered extremely severe casualties and contained some of the best men ever known. Praise for One Hell of a War... "One Hell of a War" is one of those books you simply can’t put down. It should come with a carrying handle and a sign warning "Do Not Disturb"…one of the most enjoyable WW2 books to date. -Phil Hodges for War History Online I love to read WWII history, and One Hell of a War takes the reader into the foxhole and onto the battlefield like no other book I have read … this is a must read book. -Jim Ravella, President, Folds of Honor Foundation It would be wonderful if every unit who fought during the war had a book like this portraying what was accomplished and how terrible war is for the men who actually fight it. -Gayalyn Wojtowicz, daughter of S/Sgt. Guyowen H. Howard, Sr. 317/B OUTSTANDING! “One Hell of a War” is a magnificent and masterfully told story that effortlessly weaves together the historical operations of one of Patton’s infantry regiments and first-hand accounts like no other book that I have read. A book this excellent is a rarity and should be on every professional reading list. -Colonel Frank Athanason, USA (Ret), Past National Commander of the Military Order of the Purple Heart Dean Dominique's careful research and editing of Colonel James Hayes' combat memoirs rings true in a book that is both a scholarly work and an exciting read. Trust me, when you reach the section about the fighting and cold weather during the Battle of the Bulge, you'll want to put on a coat; it's that good. -Alexander Barnes; Author of "In a Strange land; The American Occupation of Germany 1918-1923." A remarkable story about an infantry regiment during WWII that played a key role in operations in Europe. Dean does a masterful job of weaving the personal accounts into the historical context of the major operations. With so few WWII veterans left, books like these are valuable resources. -Rich Killblane, Author of "The Filthy Thirteen; From the Dustbowl to Hitler’s Eagle’s Nest: The 101st Airborne’s Most Legendary Squad of Combat Paratroopers." Dean Dominique's new book, “One Hell of a War," knocks it out of the ballpark and is one of the best books I've read…You won't be able to put it down. -Andrew Z.

    Countless behaviors separate us from the rest of the animal kingdom, but all of them can be traced one way or another to six traits that are unique to the human race—our big toe, our opposable thumb, our oddly shaped pharynx, and our ability to laugh, kiss, and cry. At first glance these may not seem to be connected but they are. Each marks a fork in the evolutionary road where we went one way and the rest of the animal kingdom went another. Each opens small passageways on the peculiar geography of the human heart and mind.Walter weaves together fascinating insights from complexity theory, the latest brain scanning techniques, anthropology, artificial intelligence, cognitive psychology, and robotics to explore how the smallest of changes over the past six million years – all shaped by the forces of evolution -- have enabled a primate once on the brink of extinction to evolve into a creature that would one day create all of the grand and exuberant edifices of human culture.As the story of each trait unfolds, Walter explains why our brains grew so large and complex, why we find one another sexually attractive, how toolmaking laid the mental groundwork for language, why we care about what others think, and how we became the creature that laughs and cries and falls in love. Thumbs, Toes and Tears is original, informative, and delightfully thought-provoking.

    Based on Prescribed Syllabus & New Pattern of Examination.

    The book emphasizes a general introduction to probability theory and provides a detailed discussion of specific designs and analyses that are typically encountered in ecology and environmental science. Appropriate for use as either a stand-alone or supplementary text for upper-division undergraduate or graduate courses in ecological and environmental statistics, ecology, environmental science, environmental studies, or experimental design, the Primer also serves as a resource for environmental professionals who need to use and interpret statistics daily but have little or no formal training in the subject.

    His clothing, combined with his yellow teeth, oily hair, and prominent hooked nose, made him look like Lucifer’s indigent second cousin. It soon became clear to everyone, including Robin Starling, his idealistic attorney, that he would have killed Bill Hill if he had felt like it. The only question was, had he felt like it back on that brisk March day?

    Many of those fortunate enough to have regular employment have been striking, over long hours and insufficient pay. Meanwhile, in the fishing village of Blackrock, James and Mary face their greatest challenge yet, which forces the healing of a breach between two members of the McGrother family. While amends are being made in Ireland, the situation is very different in America, when a dark secret rears its ugly head. Can Patrick forgive someone he believes abused his trust? Is it too late for Catherine to make amends?

    - A mostly fictional story with a mix of technical sniper knowledge, geopolitical strategy, medical horror and military humor. Reviews: "It’s epic, riveting, and incredibly informative; it will really strike a chord with today’s readers." - Elite Authors "Wow, what a ride! You obviously put a lot of time and thought into developing your characters and the story itself, and I think the end result is quite an accomplishment. The progression of events flows nicely, creating lots of suspense, and you’ve created some nice depth by using multiple perspectives. As a die-hard horror fan myself, I loved the Easter eggs you included throughout. Each one made me feel like I was in on an awesome inside joke. Great job!" - Editorial Team

    A young man older than most, he went on to do his duty when called. Mr. Jackel was one of many in the generation that truthfully saved the world and made it a much better place for those who would become his children and grandchildren. In Lucky Infantryman, Eddie Jackel spins a wonderful story of great historical significance. This is an account every American should read. In the telling of his time in training for and in going to war, Ed Jackel does not glorify the events, does not politicize. He merely tells a soldier’s story with all the genuineness and grit of growing up in America and being called on to do the seemingly impossible. This narrative is important for the historians of our times and the future. Eddie Jackel, an average American from the Lower East Side, one of many young men from all over the United States, captures the essence and flavor of America in the mid 1940s. To Eddie Jackel, and all the others who served, we say, “Thank you.”

    Describes how fractals were discovered, explains their unique properties, and discusses the mathematical foundation of fractals.

    In its structure and content, the Anthology is intended to complement the Companion to Bioethics, edited by the same scholars. The Anthology is independent of any particular approach to bioethics. Can be used as a source book to complement the Companion to Bioethics. Probes more deeply than the standard anthologies into the foundations of bioethics. More global in approach than competition.