Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    But how can it be defined? In this highly readable introduction the mysteries of this most elusive of concepts are unraveled, casting a critical light upon the way we live now, from the politicizing of museumculture to the cult of the politically correct. The key postmodernist ideas are explored and challenged, as they figure in the theory, philosophy, politics, ethics and artwork of the period, and it is shown how they have interacted within a postmodernist culture.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundredsof key topics, from philosophy to Freud, quantum theory to Islam.

    These, along with the introduction of the oral contraceptive, have altered all of our lives. There has also been an increase in the recreational use and abuse of drugs in the Western world. This Very Short Introduction gives a non-technical account of how drugs act on the body and how therapeutic drugs are developed and tested, then goes on to review both legal (prescription, alcohol, nicotine, and caffeine) and illegal drugs, and discuss current ideas about why some drugs are addictive, and whether drug laws need reform.

    More than twice the size of the United States, it was the great threat of the Cold War until it suddenly collapsed in 1991. Now, almost twenty years after the dissolution of this vast empire, what are we to make of its existence? Was it a heroic experiment, an unmitigated disaster, or a viable if flawed response to the modern world? Taking a fresh approach to the study of the Soviet Union, this Very Short Introduction blends political history with an investigation into Soviet society and culture from 1917 to 1991. Stephen Lovell examines aspects of patriotism, political violence, poverty, and ideology, and provides answers to some of the big questions about the Soviet experience. Throughout, the book takes a refreshing thematic approach to the history of the Soviet Union and it provides an up-to-date consideration of the Soviet Union's impact and what we have learnt since its end.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    Egyptian Mythology: A Very Short Introduction explains the cultural and historical background to the fascinating and complex world of Egyptian myth, with each chapter dealing with a particular theme.To show the variety of source material for Egyptian myth, each chapter features a particular object--such as the obelisk known as Cleopatra's Needle, a golden statue of Tutankhamun, and a papyrus containing a story in which the Egyptian gods behave outrageously--which is illustrated by a photograph or line-drawing. The myth "The Contendings of Horus and Seth" is looked at in detail, and the many interpretations it has provoked are examined. In addition to a list of major deities and myths, there are explanations of related topics such as how hieroglyphs work, royal names and titles, and the Egyptian cosmos. There is also a timeline of Egyptian history, a glossary of technical terms and an up-to-date bibliography.

    Kevin Passmore opens his book with a series of scenes from fascist life--a secret meeting of the Romanian Iron Guard; Mussolini meeting the king of Italy; a rally of Hungarian doctors calling for restrictions on the number of Jews entering the profession. He then looks at the paradoxes of fascism through its origins in the political and social crisis of the late nineteenth century, the history of fascist movements and regimes in Italy and Germany, and the fortunes of failed fascist movements in Romania, Hungary and Spain. He shows how fascism employs propaganda and popular culture to propagate itself and how it exported its ideas outside Europe, through Nazi and Spanish post-war escape routes to Latin America. The book concludes with a discussion of the recent revival of the extreme right in Austria, Italy, France, and Russia.

    It is truly a vital field, central to the health of society, but it is often poorly understood, largely due to misrepresentations in the media. In this Very Short Introduction, an internationally recognized authority on epidemiology, Dr. Rodolfo Saracci, provides a wealth of information on this key field, dispelling some of the myths surrounding the study of epidemiology, and explaining what epidemiology is and how vital it is to the discovery, control, and prevention of disease in world populations. Dr. Saracci provides a general explanation of the principles behind clinical trials, and explains the nature of basic statistics concerning disease. He also looks at the ethical and political issues related to obtaining and using information concerning patients, and trials involving placebos.

    Continuously in print since 1932, Ortega's vision of Western culture as sinking to its lowest common denominator and drifting toward chaos brought its author international fame and has remained one of the influential books of the 20th century.

    Even the simplest system of cause and effect can be subject to chaos, denying us accurate predictions of its behaviour, and sometimes giving rise to astonishing structures of large-scale order. Our growing understanding of Chaos Theory is having fascinating applications in the real world - from technology to global warming, politics, human behaviour, and even gambling on the stock market. Leonard Smith shows that we all have an intuitive understanding of chaotic systems. He uses accessible maths and physics (replacing complex equations with simple examples like pendulums, railway lines, and tossing coins) to explain the theory, and points to numerous examples in philosophy and literature (Edgar Allen Poe, Chang-Tzu, Arthur Conan Doyle) that illuminate the problems. The beauty of fractal patterns and their relation to chaos, as well as the history of chaos, and its uses in the real world and implications for the philosophy of science are all discussed in this Very Short Introduction.

    Readers meet a people highly skilled in sculpture, astronomy, city planning, poetry, and philosophy, who were also profoundly committed tocosmic regeneration through the thrust of the ceremonial knife and through warfare. Dav�d Carrasco looks beyond Spanish accounts that have colored much of the Western narrative to let Aztec voices speak about their origin stories, the cosmic significance of their capital city, their methods of childrearing, and the contributions women made to daily life and the empire. Carrasco discusses the arrival of the Spaniards, contrasts Aztec mythical traditions about the origins of their city with actual urban life in Mesoamerica, and outlines the rise of the Aztec empire. He also explores Aztecreligion, which provided both justification for and alternatives to warfare, sacrifice, and imperialism, and he sheds light on Aztec poetry, philosophy, painting, and especially monumental sculpture and architecture. He concludes by looking at how the Aztecs have been portrayed in Western thought, art, film, and literature as well as in Latino culture and arts.

    In thisVery Short Introduction, Alan Taylor presents an engaging overview of the best of this new scholarship. He shows that American colonization derived from a global expansion of European exploration and commerce that began in the fifteenth century. The English had to share the stage with the French, Spanish, Dutch, and Russians, each of whom created alternative Americas. By comparing the diverse colonies of rival empires, Taylor recovers what was truly distinctive about the English enterprise in North America. He focuses especially on slavery as central to the economy, culture, and politicalthought of the colonists and restores the importance of native peoples to the colonial story. To adapt to the new land, the colonists needed the expertise, guidance, alliance, and trade of the Indians who dominated the interior. This historical approach emphasizes the ability of the diverse nativesto adapt to the newcomers and to compel concessions from them.This Very Short Introduction describes an intermingling of cultures and of microbes, plants, and animals--from different continents that was unparalleled in global history.Oxford's Very Short Introductions series offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, Literary Theory to History, and Archaeology to the Bible. Not simply a textbook of definitions, each volume in this series provides trenchantand provocative--yet always balanced and complete--discussions of the central issues in a given discipline or field. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how the subject has developed and how it has influenced society. Eventually, theseries will encompass every major academic discipline, offering all students an accessible and abundant reference library. Whatever the area of study that one deems important or appealing, whatever the topic that fascinates the general reader, the Very Short Introductions series has a handy andaffordable guide that will likely prove indispensable.

    Now, in this superb compact history, Eric Rauchway offers an informed account of the New Deal and the Great Depression, illuminating its successes and failures.Rauchway first describes how the roots of the Great Depression lay in America's post-war economic policies--described as laissez-faire with a vengeance--which in effect isolated our nation from the world economy just when the world needed the United States most. He shows how the magnitude of theresulting economic upheaval, and the ineffectiveness of the old ways of dealing with financial hardships, set the stage for Roosevelt's vigorous (and sometimes unconstitutional) Depression-fighting policies. Indeed, Rauchway stresses that the New Deal only makes sense as a response to this globaleconomic disaster. The book examines a key sampling of New Deal programs, ranging from the National Recovery Agency and the Securities and Exchange Commission, to the Public Works Administration and Social Security, revealing why some worked and others did not. In the end, Rauchway concludes, it wasthe coming of World War II that finally generated the political will to spend the massive amounts of public money needed to put Americans back to work. And only the Cold War saw the full implementation of New Deal policies abroad--including the United Nations, the World Bank, and the InternationalMonetary Fund.Today we can look back at the New Deal and, for the first time, see its full complexity. Rauchway captures this complexity in a remarkably short space, making this book an ideal introduction to one of the great policy revolutions in history.About the Series: Oxford's Very Short Introductions offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, and Literary Theory to History. Not simply a textbook of definitions, each volume provides trenchant and provocative--yet alwaysbalanced and complete--discussions of the central issues in a given topic. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how it has developed and influenced society. Whatever the area of study, whatever the topic that fascinates the reader, theseries has a handy and affordable guide that will likely prove indispensable.

    The author illustrates important aspects of Africa's history with a range of fascinating historical examples, drawn from over 5 millennia across this vast continent. The multitude of topics that the reader will learn about in this succinct work include the unity and diversity of African cultures, slavery, religion, colonial conquest, the diaspora, and the importance of history in understanding contemporary Africa. The book examines questions such as: Who invented the idea of "Africa"? How is African history pieced together, given such a lack of documentary evidence? How did Africa interact with the world 1,000 years ago? Africa has been known as 'the cradle of mankind', and its recoverable history stretches back to the Pharaohs. But the idea of studying African history is itself new, and the authors show why it is still contested and controversial. This VSI, the first concise work of its kind, will prove essential reading for anyone interested in the African continent and the diversity of human history.

    This is the only introduction to Romanticism that incorporates not only the English but the Continental movements, and notonly literature but music, art, religion, and philosophy. Balancing lively details with intriguing topics, it sheds light on such subjects as the Sensibility movement, which preceded Romanticism; the rising prestige of the poet as inspired prophet; the suffering and neglect of the poet; therather different figure of the poetess; Romanticism as a religious trend; Romantic philosophy and science; and Romantic responses to the French Revolution, the Orient, gypsies, and the condition of women. Ferber offers a definition and several general propositions about this very diverse movement, as well as a discussion of the word Romantic and where it came from. Finally, some two hundred authors or artists are cited or quoted, many at length, including Blake, Wordsworth, Coleridge, Byron, Shelley, Keats, Emerson, Hugo, Goethe, Pushkin, Beethoven, Berlioz, Chopin, and Delacroix.

    It had a population of sixty million people spread across lands encircling the Mediterranean and stretching from northern England to the sun-baked banks of the Euphrates, and from the Rhine to the North African coast. It was, above all else, anempire of force--employing a mixture of violence, suppression, order, and tactical use of power to develop an astonishingly uniform culture.Here, historian Christopher Kelly covers the history of the Empire from Augustus to Marcus Aurelius, describing the empire's formation, and its political, religious, cultural, and social structures. It looks at the daily lives of the Empire's people: both those in Rome as well as those living in itsfurthest colonies. Romans used astonishing logistical feats, political savvy, and military oppression to rule their vast empire. This Very Short Introduction examines how they romanised the cultures they conquered, imposing their own culture in order to subsume them completely. The book also looksat how the Roman Empire has been considered and depicted in more recent times, from the writings of Edward Gibbon to the Hollywood blockbuster Gladiator. It will prove a valuable introduction for readers interested in classical history.