Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

    Kobe-ologists will devour this book, reveling in the anecdotes about his intensity & the engaging game recaps." —Associated Press“Every superhero needs an origin story.” –Jeff PearlmanThe inside look at one of the most captivating and consequential figures in our culture—with never-before-heard interviews.Kobe Bryant’s death in January 2020 did more than rattle the worlds of sports and celebrity. The tragedy of that helicopter crash, which also took the life of his daughter Gianna, unveiled the full breadth and depth of his influence on our culture, and by tracing and telling the oft-forgotten and lesser-known story of his early life, The Rise promises to provide an insight into Kobe that no other analysis has.In The Rise, readers will travel from the neighborhood streets of Southwest Philadelphia—where Kobe’s father, Joe, became a local basketball standout—to the Bryant family’s isolation in Italy, where Kobe spent his formative years, to the leafy suburbs of Lower Merion, where Kobe’s legend was born. The story will trace his career and life at Lower Merion—he led the Aces to the 1995-96 Pennsylvania state championship, a dramatic underdog run for a team with just one star player—and the run-up to the 1996 NBA draft, where Kobe’s dream of playing pro basketball culminated in his acquisition by the Los Angeles Lakers.In researching and writing The Rise, Mike Sielski had a terrific advantage over other writers who have attempted to chronicle Kobe’s life: access to a series of never-before-released interviews with him during his senior season and early days in the NBA. For a quarter century, these tapes and transcripts preserved Kobe’s thoughts, dreams, and goals from his teenage years, and they contained insights into and told stories about him that have never been revealed before.This is more than a basketball book. This is an exploration of the identity and making of an icon and the effect of his development on those around him—the essence of the man before he truly became a man.

    It is William Nolen's story of his transformation from student to practitioner, from a brash medical school graduate to a surgeon possessing skill and judgment. And, as happens in the best memoirs, with his brilliant flash of self-discovery William Nolen illuminates the world outside himself.First published in 1970, The Making of a Surgeon received critical acclaim and touched a world audience. The book's universal themes propelled it to the rarefied heights of a best seller. In this reprinted edition, with a foreword by the author's daughter, his classic returns.

    Doctors predicted that she would never intellectually develop beyond the abilities of a small child. Although she made some progress after years of intensive behavioral and communication therapy, Carly remained largely unreachable. Then, at the age of ten, she had a breakthrough. While working with her devoted therapists Howie and Barb, Carly reached over to their laptop and typed in "HELP TEETH HURT," much to everyone's astonishment. This was the beginning of Carly's journey toward self-realization. Although Carly still struggles with all the symptoms of autism, which she describes with uncanny accuracy and detail, she now has regular, witty, and profound conversations on the computer with her family, her therapists, and the many thousands of people who follow her via her blog, Facebook, and Twitter. In Carly's Voice, her father, Arthur Fleischmann, blends Carly's own words with his story of getting to know his remarkable daughter. One of the first books to explore firsthand the challenges of living with autism, it brings readers inside a once-secret world and in the company of an inspiring young woman who has found her voice and her mission.

    Nadine Burke Harris was already known as a crusading physician delivering targeted care to vulnerable children. But it was Diego — a boy who had stopped growing after a sexual assault — who galvanized her journey to uncover the connections between toxic stress and lifelong illnesses.The news of Burke Harris’s research is just how deeply our bodies can be imprinted by ACEs—adverse childhood experiences like abuse, neglect, parental addiction, mental illness, and divorce. Childhood adversity changes our biological systems, and lasts a lifetime.  For anyone who has faced a difficult childhood, or who cares about the millions of children who do, the scientific insight and innovative, acclaimed health interventions in The Deepest Well represent hope for preventing lifelong illness for those we love and for generations to come​.

    I stroked his cheek, whispered, it’s really you…Dov and Yitzhak live in a small village in the mountains of Hungary, isolated both from the world and from the horrors of the war. But one day in 1944, everything changes. The Nazis storm the homes of the Jewish villagers and inform them they have one hour. One hour before the train will take them to Auschwitz.Six decades later, from the safety of their living rooms at home in Israel, the brothers finally break their silence to a friend who will never let their stories be forgotten.Told in a poetic style reminiscent of Atwood and Salinger, Malka Adler has penned a visceral yet essential read for those who have found strength, solace and above all, hope, in books like The Choice, The Librarian of Auschwitz and The Tattooist of Auschwitz.This paperback includes an exclusive 14-page P.S. section with an author Q, an Author’s Note and a reading group guide.Praise for The Brothers of Auschwitz‘I sat down and read this within a few hours, my wife is now reading it and it is bringing tears to her eyes’ Amazon reviewer‘The story is so incredible and the author writes so beautifully that it is impossible to stay indifferent. I gave the book to my mom and she called me after she finished crying and telling me how much she loved it’ Amazon reviewer‘It is a book we all must read, read in order to know … It is harsh, enthralling, earth-shattering, rattling – but we must. And nothing less’ Aliza Ziegler, Editor-in-Chief at Proza Books, Yedioth Ahronoth Publishing House‘Great courage is needed to write as Adler does – without softening, without beautifying, without leaving any room to imagination’ Yehudith Rotem, Haaretz newspaper‘This is a book we are not allowed not to read’ Leah Roditi, At Magazine

    It left him sleepless, crippled, wracked with pain--a shell of himself. After months of seeing doctors and descending deeper into a physical inferno, he discovered that he had a disease which according to CDC definitions does not actually exist: the chronic form of Lyme disease, a hotly contested condition that devastates the lives of tens of thousands of people but has no official recognition--and no medically approved cure.From a rural dream house that now felt like a prison, Douthat's search for help takes him off the map of official medicine, into territory where cranks and conspiracies abound and patients are forced to take control of their own treatment and experiment on themselves. Slowly, against his instincts and assumptions, he realizes that many of the cranks and weirdos are right, that many supposed hypochondriacs are victims of an indifferent medical establishment, and that all kinds of unexpected experiences and revelations lurk beneath the surface of normal existence, in the places underneath.The Deep Places is a story about what happens when you are terribly sick and realize that even the doctors who are willing to treat you can only do so much. Along the way, Douthat describes his struggle back toward health with wit and candor, portraying sickness as the most terrible of gifts. It teaches you to appreciate the grace of ordinary life by taking that life away from you. It reveals the deep strangeness of the world, the possibility that the reasonable people might be wrong, and the necessity of figuring out things for yourself. And it proves, day by dreadful day, that you are stronger than you ever imagined, and that even in the depths there is always hope.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Amy Bloom began to notice changes in her husband, Brian: He retired early from a new job he loved; he withdrew from close friendships; he talked mostly about the past. Suddenly, it seemed there was a glass wall between them, and their long walks and talks stopped. Their world was altered forever when an MRI confirmed what they could no longer ignore: Brian had Alzheimer's disease.Forced to confront the truth of the diagnosis and its impact on the future he had envisioned, Brian was determined to die on his feet, not live on his knees. Supporting each other in their last journey together, Brian and Amy made the unimaginably difficult and painful decision to go to Dignitas, an organization based in Switzerland that empowers a person to end their own life with dignity and peace.In this heartbreaking and surprising memoir, Bloom sheds light on a part of life we so often shy away from discussing--its ending. Written in Bloom's captivating, insightful voice and with her trademark wit and candor, In Love is an unforgettable portrait of a beautiful marriage, and a boundary-defying love.

    . . and an unusual occupation. When she impulsively applies to be a mortuary technician and is offered the position, she has no idea that her decision to accept will be one of the most momentous of her life. “What I didn’t realize then,” she writes, “was that I was about to start one of the most amazing jobs you can do.”To Williams, life in the mortuary is neither grim nor frightening. She introduces readers to a host of unique characters: pathologists (many eccentric, some utterly crazy), undertakers, and the man from the coroner’s office who sings to her every morning. No two days are alike, and while Williams’s sensitivity to the dead never wavers, her tales from the crypt range from mischievous to downright shocking. Readers won’t forget the fitness fanatic run over while doing nighttime push-ups on the road, the man so large he had to be carted in via refrigerated truck, or the guide dog who led his owner onto railway tracks—and left him there. The indomitable Williams never bats an eye, even as she is confronted—daily—with situations that would leave the rest of us speechless.

    By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.

    A heartbreaking, wry, brutally honest, and creative play on a personal ad—in which a dying wife encouraged her husband to go on and find happiness after her demise—the column quickly went viral, reaching more than five million people worldwide.In My Wife Said You May Want to Marry Me, Jason describes what came next: his commitment to respecting Amy’s wish, even as he struggled with her loss. Surveying his life before, with, and after Amy, Jason ruminates on love, the pain of watching a loved one suffer, and what it means to heal—how he and their three children, despite their profound sorrow, went on. Jason’s emotional journey offers insights on dying and death and the excruciating pain of losing a soulmate, and illuminates the lessons he learned.As he reflects on Amy’s gift to him—a fresh start to fill his empty space with a new story—Jason describes how he continues to honor Amy’s life and her last wish, and how he seeks to appreciate every day and live in the moment while trying to help others coping with loss. My Wife Said You May Want to Marry Me is the poignant, unreserved, and inspiring story of a great love, the aftermath of a marriage ended too soon, and how a surviving partner eventually found a new perspective on life’s joys in the wake of tremendous loss.