In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    In existence for some hundred million years, it was discovered only recently. Exploring its evolution, its daily existence, and its journey from ticks to mice to deer to humans, Karlen lucidly examines the life and world of this recently prominent germ. He also describes how it attacks the human body, and how by changing the environment, people are now much more likely to come into contact with it. Charming and thorough and smart, this book is a wonderfully written biography of your not so typical biographical subject.

    The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including  the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept;  the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes.

    Women and Sabarimala is a rare book and is written from a woman’s perspective, explaining the nature of the temple through India’s traditional knowledge systems, such as Ayurveda, Chakras, Tantra and Agama Shastra. At the same time, the author’s personal experiences simplify the understanding of these deep sciences, providing a glimpse into how temples impact the human physiology and, in particular, women’s menstrual cycles. This book will change the way Hindu temples, especially Sabarimala, are perceived and experienced.

    Yet something about our species distinguished it from the pack, and ultimately led to its survival while the rest became extinct. Just what was it that allowed Homo sapiens to become masters of the planet? Ian Tattersall, curator emeritus at the American Museum of Natural History, takes us deep into the fossil record to uncover what made humans so special. Surveying a vast field from initial bipedality to language and intelligence, Tattersall argues that Homo sapiens acquired a winning combination of traits that was not the result of long-term evolutionary refinement. Instead, the final result emerged quickly, shocking our world and changing it forever.

    In his classic The Age of Spiritual Machines, he argued that computers would soon rival the full range of human intelligence at its best. Now he examines the next step in this inexorable evolutionary process: the union of human and machine, in which the knowledge and skills embedded in our brains will be combined with the vastly greater capacity, speed, and knowledge-sharing ability of our creations.

    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

    Jill Walker Rettberg analyses these and related genres as three intertwined modes of self-representation: visual, written and quantitative. Rettberg explores topics like the meaning of Instagram filters, smartphone apps that write your diary for you, and the ways in which governments and commercial entities create their own representations of us from the digital traces we leave behind as we go through our lives.

    Our sense of its age was vague and vastly off the mark, and much of the knowledge of our own species’ history was a set of fantastic myths and fairy tales. In the tradition of The Microbe Hunters and Gods, Graves, and Scholars, Sean Carroll leads a rousing voyage that recounts the most important discoveries in two centuries of natural history: from Darwin’s trip around the world to Charles Walcott’s discovery of pre-Cambrian life in the Grand Canyon; from Louis and Mary Leakey’s investigation of our deepest past in East Africa to the trailblazers in modern laboratories who have located a time clock in our DNA.

    The Chronic Cough Enigma is written for people who have been coughing for months or years and cannot get useful answers from their doctors.More than 20 million Americans suffer from what is known as enigmatic chronic cough. This book provides insights from Dr. Jamie Koufman’s almost forty years of successfully managing thousands of long-suffering cough patients. Indeed, the typical chronic cough patient who comes to her office has been coughing for more than a decade. This book provides the many who suffer from chronic cough new and potentially life-changing information and the potential to be cured.

    Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

    Welcome to laughing until it hurts while covered in bodily fluids. Welcome to simple math at very high stakes. Welcome to an incredibly inappropriate sense of humor. Welcome to serving people on the most stressful days of their lives. Welcome to putting your hands in places you never imagined they'd be. Welcome to your front row seat to the ballad of life and death. That's not the welcome that this nurse was looking for, but that's the one he got. Irreverent and audacious, this brutally honest memoir covers what it’s like to come of age in an American Hospital. Welcome to a rollicking peak behind the curtain to what medical providers, and the health care system, are truly like.

    and trying, and trying some more? How far do you go to achieve your dream of having children?So Close is the heart wrenching, exhilarating, devastatingly funny story of Tertia Albertyn's battle with infertility. Tertia wanted a baby so badly she went through nine IVFs. Most people give up after the third.I don't think I am being brave at all. I am just too terrified NOT to try again.In her worst nightmare she could never have imagined that making a baby would take her four years, each treatment bringing her and her husband Marko closer and closer to creating their family.During Tertia's journey everything that can go wrong does go wrong. Until, finally, everything goes just right.Tertia is as hilarious as she is irrepressible, as approachable as she is knowledgeable. If you are struggling with infertility, have triumphed over infertility or have felt empathy with someone who is going through this experience, you will find a friend in Tertia.

    Shubin describes how over the last half-century, scientists have been able to explore how genetic recipes build bodies during embryological development--how these inventions and adaptations occur in a nonprogressive manner in different contexts, at different speeds. Paleontology has been transformed over the last 50 years by tools and techniques of molecular biology--and it is that revolution in our understanding of the evolution of life that Shubin traces here. Each of us is a mosaic of precursors that came about at different times and places, with deep rooted connections across species that Darwin, for all he understood, could never even have imagined.

    An exploration of technology used by ancient civilizations and the support it provides for certain biblical interpretations.