Inheritance Conventional wisdom dictates that our genetic destiny is fixed at conception. But Dr. Moalem's groundbreaking book shows us that the human genome is far more fluid and fascinating than your ninth grade biology teacher ever imagined. By bringing us to the bedside of his unique and complex patients, he masterfully demonstrates what rare genetic conditions can teach us all about our own health and well-being. In the brave new world we're rapidly rocketing into, genetic knowledge has become absolutely crucial. Inheritance provides an indispensable roadmap for this journey by teaching you: -Why you may have recovered from the psychological trauma caused by childhood bullying-but your genes may remain scarred for life. -How fructose is the sugar that makes fruits sweet-but if you have certain genes, consuming it can buy you a one-way trip to the coroner's office. -Why ingesting common painkillers is like dosing yourself repeatedly with morphine-if you have a certain set of genes. -How insurance companies legally use your genetic data to predict the risk of disability for you and your children-and how that impacts the coverage decisions they make for your family. -How to have the single most important conversation with your doctor-one that can save your life. And finally: -Why people with rare genetic conditions hold the keys to medical problems affecting millions. In this trailblazing book, Dr. Moalem employs his wide-ranging and entertaining interdisciplinary approach to science and medicine-- explaining how art, history, superheroes, sex workers, and sports stars all help us understand the impact of our lives on our genes, and our genes on our lives. Inheritance will profoundly alter how you view your genes, your health--and your life.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a freak, but a limbless reptile-a snake-a successful variation?What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.

    Darwin wondered why these birds were confined to remote islands at the tip of South America, sensing a larger story, but he set this mystery aside and never returned to it. Almost two hundred years later, Jonathan Meiburg takes up this chase. He takes us through South America, from the fog-bound coasts of Tierra del Fuego to the tropical forests of Guyana, in search of these birds: striated caracaras, which still exist, though they're very rare. He reveals the wild, fascinating story of their history, origins, and possible futures. And along the way, he draws us into the life and work of William Henry Hudson, the Victorian writer and naturalist who championed caracaras as an unsung wonder of the natural world, and to falconry parks in the English countryside, where captive caracaras perform incredible feats of memory and problem-solving. A Most Remarkable Creature is a hybrid of science writing, travelogue, and biography, as generous and accessible as it is sophisticated, and absolutely riveting.

    Solo is a cadaver dog. What started as a way to harness Solo’s unruly energy and enthusiasm soon became a calling that introduced Warren to the hidden and fascinating universe of working dogs, their handlers, and their trainers. Solo has a fine nose and knows how to use it, but he’s only one of many thousands of working dogs all over the United States and beyond. In What the Dog Knows, Warren uses her ongoing work with Solo as a way to explore a captivating field that includes cadaver dogs, drug- and bomb-detecting K9s, tracking and apprehension dogs—even dogs who can locate unmarked graves of Civil War soldiers and help find drowning victims more than two hundred feet below the surface of a lake. Working dogs’ abilities may seem magical or mysterious, but Warren shows the multifaceted science, the rigorous training, and the skilled handling that underlie the amazing abilities of dogs who work with their noses. Warren interviews cognitive psychologists, historians, medical examiners, epidemiologists, and forensic anthropologists, as well as the breeders, trainers, and handlers who work with and rely on these remarkable and adaptable animals daily. Along the way, she discovers story after story that proves the impressive capabilities—as well as the very real limits—of working dogs and their human partners. Clear-eyed and unsentimental, Warren explains why our partnership with dogs is woven into the fabric of society and why we keep finding new uses for their wonderful noses.

    A Sunday Telegraph top 15 Christmas gift book of 2019 A dog is for life, but an old dog's wisdom is for ever. 'A truly heartwarming book - a perfect gift for any dog lover' Trisha Ashley'The Wisdom of Old Dogs is an absolute must-have' Countryside Magazine'A beautiful read that will leave dog owners and animal lovers brimming over with love and gratitude' Woman's Way Magazine Full of practical advice, uplifting stories, and scientific expertise, this book reveals how dogs can be a constant source of wisdom, comfort and love in their old age.The perfect Christmas present for anyone who treasures these wonderful animals.

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    Her fascinating and wide-ranging work provides clear explanations of the science surrounding keystone predators and considers how this notion can help provide practical solutions for restoring ecosystem health and functioning.Eisenberg examines both general concepts and specific issues, sharing accounts from her own fieldwork to illustrate and bring to life the ideas she presents. She considers how resource managers can use knowledge about trophic cascades to guide recovery efforts, including how this science can be applied to move forward the bold vision of rewilding the North American continent. In the end, the author provides her own recommendations for local and landscape-scale applications of what has been learned about interactive food webs.At their most fundamental level, trophic cascades are powerful stories about ecosystem processes of predators and their prey, of what it takes to survive in a landscape, of the flow of nutrients. The Wolf’s Tooth is the first book to focus on the vital connection between trophic cascades and restoring biodiversity and habitats, and to do so in a way that is accessible to a diverse readership.

    In this book, he builds on that theme by showing why this is the luckiest time yet to be alive, giving you the keys to the new kingdom of wellness.Medicine is undergoing rapid change. In the old world, you followed general principles and doctors treated you based on broad, one-size-fits all solutions. In this new golden age, you’ll be able to take full advantage of the latest scientific findings and leverage the power of technology to customize your care. Only those who know how to access and adapt to these breakthroughs—without being distracted by hyped ideas and bad medicine—will benefit. Imagine being able to get fit and lose weight without dieting, train your immune system to fight cancer, edit your DNA to avoid a certain fate, erase the risk of a heart attack, reverse aging, and know exactly which drugs to take to optimize health with zero side effects.That’s the picture of the future that you can enter starting today. Welcome to The Lucky Years.

    The more than 1,200 color photographs and two dozen line drawings include numerous exceptionally striking images. The giant silk moths, tiger moths, and many other species covered include forest pests, common garden guests, economically important species, and of course, the Mescal Worm and Mexican Jumping Bean caterpillars. Full-page species accounts cover almost 400 species, with up to six images per species including an image of the adult plus succinct text with information on distribution, seasonal activity, foodplants, and life history. These accounts are generously complemented with additional images of earlier instars, closely related species, noteworthy behaviors, and other intriguing aspects of caterpillar biology.Many caterpillars are illustrated here for the first time. Dozens of new foodplant records are presented and erroneous records are corrected. The book provides considerable information on the distribution, biology, and taxonomy of caterpillars beyond that available in other popular works on Eastern butterflies and moths. The introductory chapter covers caterpillar structure, life cycles, rearing, natural enemies, photography, and conservation. The section titled Caterpillar Projects will be of special interest to educators.Given the dearth of accessible guides on the identification and natural history of caterpillars, Caterpillars of Eastern North America is a must for entomologists and museum curators, forest managers, conservation biologists and others who seek a compact, easy-to-use guide to the caterpillars of this vast region. A compact guide to nearly 700 caterpillars east of the Mississippi, from forest pests to garden guests and economically important species 1,200 color photos and 24 line drawings enable easy identification Full-page species accounts with image of adult insect for almost 400 species, plus succinct text on distribution and other vital information Many caterpillars illustrated here for the first time Current information on distribution, biology, and taxonomy not found in other popular works A section geared toward educators, Caterpillar Projects An indispensable resource for all who seek an easy-to-use guide to the caterpillars of this vast region

    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

    During the day, she worked with toddlers with significant delays in language development and used Augmentative and Alternative Communication (AAC) devices to help them communicate. At night, she wondered: If dogs can understand words we say to them, shouldn't they be able to say words to us? Can dogs use AAC to communicate with humans?Christina decided to put her theory to the test with Stella and started using a paw-sized button programmed with her voice to say the word "outside" when clicked, whenever she took Stella out of the house. A few years later, Stella now has a bank of more than thirty word buttons, and uses them daily either individually or together to create near-complete sentences.How Stella Learned to Talk is part memoir and part how-to guide. It chronicles the journey Christina and Stella have taken together, from the day they met, to the day Stella "spoke" her first word, and the other breakthroughs they've had since. It also reveals the techniques Christina used to teach Stella, broken down into simple stages and actionable steps any dog owner can use to start communicating with their pets.Filled with conversations that Stella and Christina have had, as well as the attention to developmental detail that only a speech-language pathologist could know, How Stella Learned to Talk will be the indispensable dog book for the new decade.

    Rochman takes an authoritative look at the latest hot-button issues in the world of pre- and postnatal testing and tells the stories of women and men struggling to understand the variety of tests and grappling with their results—revelations that are sometimes joyous, sometimes heartbreaking, and often profound.Propelled by human narratives and meticulously reported, The Gene Machine introduces us to scientists working to unlock the secrets of the human genome; gene counselors and spiritual advisers helping parents manage this complex new reality; and, of course, parents themselves, including the author, who glimpse the genetic futures of their children. The Gene Machine is both a scientific road map and a meditation on our power to shape the future, one that gets to the very core of what it means to be human.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    With the poignant insight of Animals Make Us Human and the shocking reality of Fast Food Nation—filled with history, valuable insights, and fascinating stories of the author’s experience in the field—The Bond is an important investigation into all the ways we can repair our broken bond with the animal kingdom and a thrilling chronicle of one man’s extraordinary contribution to that effort.