Brent Russell shares true-life stories of his early days as an Emergency Room doctor. Contemplative and oftentimes hilarious, Dr. Russell leads the reader through the glass doors and down the narrow halls of the ER where desperate patients, young and old, come to get well. Occasionally heart wrenching and always fast-paced, Miracles and Mayhem in the ER will have readers holding their breath one second and celebrating the next. Through his night shifts at a renowned Portland, WA hospital, Russell discovers his role, and his confidence as he treats people from all walks of life including humanity's most bizarre in the ER. Each shift brings a new, bracing story to tell.

    In this deeply personal book, humanitarian doctor and activist James Maskalyk, author of the highly acclaimed Six Months in Sudan, draws upon his experience treating patients in the world's emergency rooms. From Toronto to Addis Ababa, Cambodia to Bolivia, he discovers that although the cultures, resources and medical challenges of each hospital may differ, they are linked indelibly by the ground floor: the location of their emergency rooms. Here, on the ground floor, is where Dr. Maskalyk witnesses the story of -human aliveness---our mourning and laughter, tragedies and hopes, the frailty of being and the resilience of the human spirit. And it's here too that he is swept into the story, confronting his fears and doubts and questioning what it is to be a doctor. Masterfully written and artfully structured, Life on the Ground Floor is more than just an emergency doctor's memoir or travelogue--it's a meditation on health, sickness and the wonder of human life.

    

    Why does music evoke such powerful moods? The answers are at last be- coming clear, thanks to revolutionary neuroscience and the emerging field of evolutionary psychology. Both a cutting-edge study and a tribute to the beauty of music itself, This Is Your Brain on Music unravels a host of mysteries that affect everything from pop culture to our understanding of human nature, including: • Are our musical preferences shaped in utero? • Is there a cutoff point for acquiring new tastes in music? • What do PET scans and MRIs reveal about the brain’s response to music? • Is musical pleasure different from other kinds of pleasure?This Is Your Brain on Music explores cultures in which singing is considered an essential human function, patients who have a rare disorder that prevents them from making sense of music, and scientists studying why two people may not have the same definition of pitch. At every turn, this provocative work unlocks deep secrets about how nature and nurture forge a uniquely human obsession.

    A few (identities disguised) come from the author’s own clinical encounters.  Every scenario is followed by a brief reflection of how various modern thought leaders (ethicists, philosophers, courts, political commentators, research scientists, and medical professionals) have addressed the underlying issues.

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    Our stories are marbled into their marrow.Drawing upon her years of research and a wealth of remarkable experience, the world-renowned forensic anthropologist Professor Dame Sue Black takes us on a journey of revelation. From skull to feet, via the face, spine, chest, arms, hands, pelvis and legs, she shows that each part of us has a tale to tell. What we eat, where we go, everything we do leaves a trace, a message that waits patiently for months, years, sometimes centuries, until a forensic anthropologist is called upon to decipher it.Some of this information is easily understood, some holds its secrets tight and needs scientific cajoling to be released. But by carefully piecing together the evidence, the facts of a life can be rebuilt. Limb by limb, case by case – some criminal, some historical, some unaccountably bizarre – Sue Black reconstructs with intimate sensitivity and compassion the hidden stories in what we leave behind.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    He lifts the lid on government targets that led to poor patient care. He reveals the level of alcohol-related injuries that often bring the service to a near standstill. He shows just how bloody hard it is to look after the people who turn up at the hospital door.But he also shares the funny side - the unusual ‘accidents’ that result in with weird objects inserted in places they really should have ended up - and also the moving, tragic and heartbreaking.It really is an unforgettable read.

    I was mentally and physically broken. So fractured, I hadn't eaten properly or slept well, or even changed my expression for months. I sat in a cubicle, behind paper-thin curtains, listening to the rest of the hospital happen around me, and I shook with the effort of not crying. I was an inch away from defeat, from the acceptance of a failure I assumed would be inevitable, but I knew I had to carry on. I had to somehow walk through it.Because I wasn't the patient. I was the doctor."A frank account of mental health from both sides of the doctor-patient divide, from the bestselling author of The Trouble with Goats and Sheep and Three Things About Elsie, based on her own experience as a doctor working on a psychiatric ward.

     Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    She spent ten years training and working as an Anatomical Pathology Technologist: where the mortuary slab was her desk, and that day's corpses her task list.Past Mortems tells Carla's stories of those years, as well as investigating the body alongside our attitudes towards death - shedding light on what the living can learn from dead and the toll the work can take on the living souls who carry it out. Fascinating and insightful, Past Mortems reveals the truth about what happens when the mortuary doors swing shut or the lid of the coffin closes . . .

    The latest version is far superior, both in content and presentation, to previous versions. I give it my highest recommendation."--"Doody's Review Service"From the authors of "Basic and Clinical Pharmacology," the leading pharmacology textbook, here is the newest edition of the best review book available for medical pharmacology course exams and board examinations. This skill-building guide comes with over 1000 review questions and answers -- far more than most other pharmacology reviews -- and a chapter-based approach that facilitates use with course notes or larger texts. Features: A new full-color presentation Organized to reflect course syllabi, focusing on the clinical use and pharmacology of drug categories, rather than individual drugs Two complete practice exams A valuable appendix of test-taking strategies Chapters that include valuable learning aids such as: --Short discussion of the major concepts that underlie basic principles or drug groups--Explanatory figures and tables--Review questions followed by answers and explanations--Drug Trees in drug-oriented chapters that visually organize drug groups--A list of high-yield terms and definitions you need to know Skill Keeper questions that prompt you to review previous material to understand links between related topics A checklist of tasks you should be able to do, once you have finished the chapter Summary Tables that list the important drugs and include key information about their mechanisms of action, effects, clinical uses, pharmacokinetics, drug interactions, and toxicities

    Alongside this lifestyle, depression rates have skyrocketed: approximately 1 in 4 Americans will suffer from major depression at some point in their lives. Where have we gone wrong? Dr. Stephen Ilardi sheds light on our current predicament and reminds us: our bodies were never designed for the sleep-deprived, poorly nourished, frenzied pace of twenty-first century life. In fact, our genes have changed very little since the days of our hunter-gatherer ancestors and are still building, in effect, Stone Age bodies. Herein lies the key to breaking the cycle of depression.Inspired by the extraordinary resilience of aboriginal groups like the Kaluli of Papua New Guinea (who rarely suffer from depression), Dr. Ilardi prescribes an easy-to-follow, clinically proven program that harks back to what our bodies were originally made for-and need. Here you can find the road back to lasting health by integrating the following 6 elements into your life: an omega-3 rich diet; exercise; plenty of natural sunlight; ample sleep; social connections; and participation in meaningful tasks that leave little time for negative thoughts-all things that our ancestors had in abundance.Already, The Depression Cure program has delivered dramatic results, helping even those who have failed to respond to traditional medications. Interweaving the stories of many who have fought-and won-the battle against this debilitating illness, this groundbreaking book can illuminate the path to lifting the fog once and for all for you or a loved one.