But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    He reveals what is real and what is illusory, in the process exposing moves that can harm or even kill. Five years in the making, The Science of Yoga draws on a hidden wealth of discovery, drama, and surprising fact to cut through the fog that surrounds contemporary yoga and to show—for the first time—what is uplifting and beneficial and what is delusional, flaky, and dangerous. At heart, it illuminates the risks and rewards.Broad describes yoga as a burgeoning global industry that attracts not only curious scientists but millions of true believers and charismatic hustlers. He takes the reader on a whirlwind tour of unknown yoga that goes from old archives in Calcutta to world capitals of medical research, from storied ashrams to spotless laboratories, from sweaty yoga studios with master teachers to the cozy offices of yoga healers. In the process, he shatters myths, lays out unexpected benefits, and offers a compelling vision of how the discipline can be improved.

    Jeter. Ali. Williams. These elite legends have changed the game, achieved the unthinkable, and pushed their bodies to unbelievable limits. Joining their exclusive ranks is Tom Brady. “Brady is the healthiest great champion the NFL has ever had, both physically and mentally” (Sally Jenkins, The Washington Post). The longtime New England Patriots quarterback, who in 2017 achieved his fifth Super Bowl win and fourth Super Bowl MVP award, is widely regarded as an athlete whose training and determination pushed him from a mediocre draft position to the most-revered and respected professional football player of his generation. In The TB12 Method, Tom Brady explains how he developed his groundbreaking approach to long-term fitness, presenting a comprehensive, step-by-step guide to his personal practice. Brady offers the principles behind pliability, which is at the heart of a new paradigm shift and movement toward a more natural, healthier way of exercising, training, and living—and one that challenges some commonly held assumptions around health and wellness. Filled with lessons learned from Brady’s own peak performance training, and step-by-step action steps to help readers develop and maintain their own peak performance, The TB12 Method also advocates for more effective approaches to strength training, hydration, nutrition, supplementation, cognitive fitness, recovery, and other lifestyle choices that dramatically decrease the risk of injury while amplifying and extending performance, as well as quality of life. After using his methods for over a decade, Brady believes that the TB12 approach has made him—and can make any athlete, male or female, in any sport and at any level—achieve their own peak performance. With instructions, drills, photos, in-depth case studies that Brady himself has used, as well as personal anecdotes and experiences from on and off the field, The TB12 Method is the only book an athlete will ever need, a playbook from Brady himself that will change the game.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

    Two hours to cover twenty-six miles and 385 yards. It is running’s Everest, a feat once seen as impossible for the human body. But now we can glimpse the mountaintop. The sub-two hour marathon will require an exceptional combination of speed, mental strength, and endurance. The pioneer will have to endure more, live braver, plan better, and be luckier than anyone who has run before. So who will it be?In this spellbinding book, journalist Ed Caesar takes us into the world of elite marathoners: some of the greatest runners on earth. Through the stories of these rich characters, like Kenyan Geoffrey Mutai, around whom the narrative is built, Caesar traces the history of the marathon as well as the science, physiology, and psychology involved in running so fast for so long. And he shows us why this most democratic of races retains its brutal, enthralling appeal—and why we are drawn to test ourselves to the limit.Two Hours is a book about a beautiful sport few people understand. It takes us from big-money races in the United States and Europe to remote villages in Kenya. It’s about talent, heroism, and refusing to accept defeat. It is a book about running that is about much more than running. It is a human drama like no other.

    They ingest 8,500 milligrams of salt a day, double the recommended amount, almost none of which comes from salt shakers. It comes from processed food, an industry that hauls in $1 trillion in annual sales. In Salt Sugar Fat, Pulitzer Prize-winning investigative reporter Michael Moss shows how this happened. Featuring examples from some of the most recognizable (and profitable) companies and brands of the last half century--including Kraft, Coca-Cola, Lunchables, Kellogg, Nestlé, Oreos, Cargill, Capri Sun, and many more--Moss’s explosive, empowering narrative is grounded in meticulous, often eye-opening research. He goes inside the labs where food scientists use cutting-edge technology to calculate the "bliss point" of sugary beverages or enhance the "mouth feel" of fat by manipulating its chemical structure. He unearths marketing techniques taken straight from tobacco company playbooks to redirect concerns about the health risks of products. He talks to concerned executives who explain that they could never produce truly healthy alternatives to their products even if serious regulation became a reality. Simply put: the industry itself would cease to exist without salt, sugar, and fat.

    Food psychologist Brian Wansink revolutionizes our awareness of how much, what, and why we’re eating—often without realizing it. His findings will astound you. • Can the size of your plate really influence your appetite?• Why do you eat more when you dine with friends?• What “hidden persuaders” are used by restaurants and supermarkets to get us to overeat?• How does music or the color of the room influence how much—and how fast—we eat?• How can we “mindlessly” lose—instead of gain—up to twenty pounds in the coming year? Starting today, you can make more mindful, enjoyable, and healthy choices at the dinner table, in the supermarket, at the office—wherever you satisfy your appetite.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    In The Power of Balance, Dr Rangan Chatterjee presents an easily accessible plan for taking control of your health and your life.Everyday health revolves around Dr Chatterjee's four pillars: relaxation, food, sleep and movement. By making small, achievable changes in each of these key areas you can create and maintain good health - and avoid illness.It's not about excelling at any one pillar - what matters is the balance across all the things you do, including:· an electronic 'sabbath' once a week· aiming for 12 hours every day without food· exposure to sunlight first thing each morningBased on cutting edge research and his own experiences as a doctor, this book contains fascinating case studies from real patients. Practical and potentially life-changing, The Power of Balance is an inspiring and easy-to-follow guide to better health and happiness.

    As a newcomer to the sport and a complete unknown to the press, Chrissie's win shook up the sport. A LIFE WITHOUT LIMITS is the story of her rise to the top, a journey that has taken her around the world, from a childhood in England, to the mountains of Nepal, to the oceans of New Zealand, and the trails of Argentina, and first across the finish line.Wellington's first-hand, inspiring story includes all the incredible challenges she has faced--from anorexia to near--drowning to training with a controversial coach. But to Wellington, the drama of the sports also presents an opportunity to use sports to improve people's lives.A LIFE WITHOUT LIMITS reveals the heart behind Wellington's success, along with the diet, training and motivational techniques that keep her going through one of the world's most grueling events.

    When you meet her on the trail, you might be surprised to see she doesn’t quite fit the typical image of a long-distance runner. She’s neither skinny nor white, and she’s here to show just how misguided these stereotypes can be.In this prejudice-busting, body-positive memoir told with raw honesty, an adventurous spirit, and a sharp sense of humor, Valerio takes readers along on her journey from first-time racer to ultramarathoner and proves that anyone can become a successful athlete.

    From "The Best Way to Tie Your Shoes” to “3 Ways to Make Yourself Poop” and everything in between, these short, easy-to-use tips from reliable experts will benefit any runner.

    And because you’re already more attuned to your physical and emotional needs, and more inclined to commit to a healthier lifestyle, you're poised to live brilliantly for the thirty-plus years after menopause. All you need now is the program outlined in Younger Next Year for Women—which, for starters, will help you avoid literally 70 percent of the decay and eliminate 50 percent of the injuries and illnesses associated with getting older. How? Drawn from disciplines as varied as evolutionary biology, cell physiology, experimental psychology and anthropology, the science behind Younger Next Year is clear. Our bodies are programmed to do one of two things: either grow or decay. Sitting in front of a screen all day tells the body to decay. Taking a walk or doing yoga tells the body to grow. Loneliness and stress trigger decay; love and laughter trigger growth. Just as clear as the science is the goal: Become the active gatekeeper of your own body and gain the power to control those signals of growth and decay. Seven simple rules show the way, from #1 Exercise six days a week for the rest of your life, to #6 Care, to #7 Connect and commit. They’re called Harry’s Rules, named for the doctor and coauthor—Henry S. Lodge, M.D.—who formulated them, and who explains the precise science behind each one. But since it’s one thing to know something’s good for you and quite another to put it into practice, Dr. Lodge, the scientist, is joined by Chris Crowley—coauthor, exhorter and living example—whose brusque charm and infectious enthusiasm will actually have you living by the rules. So, congratulations. You’re now about to get younger.