The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    But this is not the whole story.Shedding light on controversial research and investigating the ferocious gender wars in biology, psychology and anthropology, Angela Saini takes readers on an eye-opening journey to uncover how women are being rediscovered. She explores what these revelations mean for us as individuals and as a society, revealing an alternative view of science in which women are included, rather than excluded.

    It shows teachers how to create an environment in which technology can effectively enhance learning. It contains a technology integration framework that builds on research and the TIP model.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    Illustrations and examples throughout show you how you can apply research to practice. Studying is made easy with a book-specific website that provides you with tutorial quizzes and links to additional related concepts. Outlines, introductions, boxes, chapter endings with main points, review questions and exercises, and internet exercises provide you with the information and practice you need to succeed in this course.

       An anthropologist and MD in the mold of Paul Farmer and Didier Fassin, Seth Holmes shows how market forces, anti-immigrant sentiment, and racism undermine health and healthcare. Holmes’s material is visceral and powerful. He trekked with his companions illegally through the desert into Arizona and was jailed with them before they were deported. He lived with indigenous families in the mountains of Oaxaca and in farm labor camps in the U.S., planted and harvested corn, picked strawberries, and accompanied sick workers to clinics and hospitals. This “embodied anthropology” deepens our theoretical understanding of how health equity is undermined by a normalization of migrant suffering, the natural endpoint of systemic dehumanization, exploitation, and oppression that clouds any sense of empathy for “invisible workers.”  Fresh Fruit, Broken Bodies is far more than an ethnography or supplementary labor studies text; Holmes tells the stories of food production workers from as close to the ground as possible, revealing often theoretically-discussed social inequalities as irreparable bodily damage done. This book substantiates the suffering of those facing the danger of crossing the border, threatened with deportation, or otherwise caught up in the structural violence of a system promising work but endangering or ignoring the human rights and health of its workers.All of the book award money and royalties from the sales of this book have been donated to farm worker unions, farm worker organizations and farm worker projects in consultation with farm workers who appear in the book.

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    Too often, overwhelmed by anatomical detail, students miss out on the functional beauty of the nervous system and its relevance to clinical practice.

    Guyton & Hall's Textbook of Medical Physiology covers all of the major systems in the human body, while emphasizing system interaction, homeostasis, and pathophysiology. This very readable, easy-to-follow, and thoroughly updated, 11th Edition features a new full-color layout, short chapters, clinical vignettes, and shaded summary tables that allow for easy comprehension of the material.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.Presents short, easy-to-read chapters in keeping with the Guyton and Hall tradition.Provides shaded summary tables for easy reference.Includes clinical vignettes, which allow readers to see core concepts applied to real-life situations.Offers specific discussions of pathophysiology in most clinical areas of medicine.Ensures a strong grasp of physiology concepts through well-illustrated discussions of the most essential principles.Now in full color! Offers access to the full text and other valuable features online via the STUDENT CONSULT website.Uses full-color illustrations throughout, including 486 figures, 277 charts and graphs, 100 brand-new line drawings, and 36 ECGs.Features a new full-color design that makes information more engaging and even easier to read.Updated throughout to reflect the latest knowledge in the field.

    Bundled (ISBN 9780534633622) textbook with InfoTrac CD-ROM.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

    Why people behave as they do is as much a focus as is their actual behavior. Through instructions given to Farrer by Bernard Second, her Apache teacher for fourteen years, readers gain insight into the importance of narrative, not just in ceremony but especially in everyday living on a contemporary Indian reservation in the American Southwest. Sights and smells are almost palpable as the author provides the best in reflexive ethnography by allowing readers to see her as a person rather than an all-knowing anthropologist. She neither romanticizes nor patronizes the Apachean people, who are presented as people with foibles as well as possessing much worthy of admiration.

    This book is the story of the life of Nisa, a member of the !Kung tribe of hunter-gatherers from southern Africa's Kalahari desert. Told in her own words--earthy, emotional, vivid--to Marjorie Shostak, a Harvard anthropologist who succeeded, with Nisa's collaboration, in breaking through the immense barriers of language and culture, the story is a fascinating view of a remarkable woman.

    Updated web links and expanded appendices provide cutting edge information on action research along with new case studies and examples.

    The book has the hallmark features for which Lippincott's Illustrated Reviews volumes are so popular: an outline format, over 600 full-color illustrations, end-of-chapter summaries, review questions, plus an entire section of clinical case studies with full-color illustrations. This edition's medical/clinical focus has been sharpened to provide a high-yield review. Five additional case studies have been included, bringing the total to nineteen. Review questions have been reformatted to comply with USMLE Step 1 style, with clinical vignettes.