Suppose, instead of thinking about organisms using genes to reproduce themselves, as we had since Mendel's work was rediscovered, we turn it around and imagine that "our" genes build and maintain us in order to make more genes. That simple reversal seems to answer many puzzlers which had stumped scientists for years, and we haven't thought of evolution in the same way since. Drawing fascinating examples from every field of biology, he paved the way for a serious re-evaluation of evolution. He also introduced the concept of self-reproducing ideas, or memes, which (seemingly) use humans exclusively for their propagation. If we are puppets, he says, at least we can try to understand our strings.

    Users of magic are in conflict with proponents of science. The dwindling Druid order is threatened with extinction. A sinister politician has used treachery and murder to rise as prime minister of the mighty Federation. Meanwhile, poring through a long-forgotten diary, the young Druid Aphenglow Elessedil has stumbled upon the secret account of an Elven girl’s heartbreak and the shocking truth about the vanished Elfstones, which once warded the lands and kept evil at bay. But never has a little knowledge been so very dangerous—as Aphenglow quickly learns when she’s set upon by assassins. Yet there can be no turning back from the road to which fate has steered her. Whoever captures the Elfstones and their untold powers will surely hold the advantage in the devastating clash to come.

    The New York Times bestselling series from Brandon Sanderson.This boxed set contains: Mistborn: The Final Empire The Well of Ascension The Hero of Ages

    King Henry still holds the crown, but his reign has long been contested by his sister Sabella, and there are many eager to flock to her banner. Internal conflict weakens Wendar's defences, drawing raiders, human and inhuman, across its borders. Terrifying portents abound and dark spirits walk the land in broad daylight.Suddenly two innocents are thrust into the midst of the conflict. Alain, a young man granted a vision by the Lady of Battles, and Liath, a young woman with the power to change the course of history. Both must discover the truth about themselves before they can accept their fates. For in a war where sorcery, not swords, may determine the final outcome, the price of failure may be more than their own lives.

    In Helgoland, he examines the enduring enigma of quantum theory. The quantum world Rovelli describes is as beautiful as it is unnerving.Helgoland is a treeless island in the North Sea where the twenty-three-year-old Werner Heisenberg made the crucial breakthrough for the creation of quantum mechanics, setting off a century of scientific revolution. Full of alarming ideas (ghost waves, distant objects that seem to be magically connected, cats that appear both dead and alive), quantum physics has led to countless discoveries and technological advancements. Today our understanding of the world is based on this theory, yet it is still profoundly mysterious.As scientists and philosophers continue to fiercely debate the meaning of the theory, Rovelli argues that its most unsettling contradictions can be explained by seeing the world as fundamentally made of relationships rather than substances. We and everything around us exist only in our interactions with one another. This bold idea suggests new directions for thinking about the structure of reality and even the nature of consciousness.Rovelli makes learning about quantum mechanics an almost psychedelic experience. Shifting our perspective once again, he takes us on a riveting journey through the universe so we can better comprehend our place in it.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Finally resorting to medication, he instantly falls into a deep sleep that lasts two hundred years. Upon waking in the twenty-second century to a strange and nightmarish place, he slowly discovers he is master of the world, revered by an adoring populace who consider him their leader. Terrified, he escapes from his chamber seeking solace—only to realize that not everyone adores him, some even wish to harm him.

    We had a flood plan in place. We could even have dealt with zombies. Probably.But no one expected the end to be quite so . . . sticky . . . or strawberry scented.

    It’s not a new problem; in fact, it’s been around for nearly 20 million years. And Nate’s spent most of his adult life working to solve it. You see, although everybody (well, almost everybody) knows that humpback whales sing (outside of human composition, the most complex songs on the planet) no one knows why. Nate, a Ph.D. in behavior biology, intends to discover the answer to this burning question—and soon.Every winter he and Clay Demolocus, his partner in the Maui Whale Research Foundation, ply the warm waters between the islands of Maui and Lanai, recording the eerily beautiful songs of the humpbacks and returning to their lab for electronic analysis. The trouble is, Nate’s beginning to wonder if he hasn’t spent just a little too much time in the sun. Either that, or he’s losing his mind. Because today, as he was shooting an I.D. photo of a humpback tail fluke, Nate could’ve sworn he saw the words “Bite Me” scrawled across the whale’s tail. . .

    They all flared into brilliance at once, then disappeared, replaced by a flat, empty black barrier. He and his best friends, Jason and Diane Lawton, had seen what became known as the Big Blackout. It would shape their lives.Life on Earth is about to get much, much stranger.

    Just about everyone has at least heard of Albert Einstein's formulation of 1905, which came into the world as something of an afterthought. But far fewer can explain his insightful linkage of energy to mass. David Bodanis offers an easily grasped gloss on the equation. Mass, he writes, "is simply the ultimate type of condensed or concentrated energy," whereas energy "is what billows out as an alternate form of mass under the right circumstances." Just what those circumstances are occupies much of Bodanis's book, which pays homage to Einstein and, just as important, to predecessors such as Maxwell, Faraday, and Lavoisier, who are not as well known as Einstein today. Balancing writerly energy and scholarly weight, Bodanis offers a primer in modern physics and cosmology, explaining that the universe today is an expression of mass that will, in some vastly distant future, one day slide back to the energy side of the equation, replacing the "dominion of matter" with "a great stillness"--a vision that is at once lovely and profoundly frightening. Without sliding into easy psychobiography, Bodanis explores other circumstances as well; namely, Einstein's background and character, which combined with a sterling intelligence to afford him an idiosyncratic view of the way things work--a view that would change the world. --Gregory McNamee

    Once a young sorcerer-bookbinder, Vella was transformed into a useful tool by one of the greatest sorcerers of history. Since then she has been collecting information, including a vital clue to the disaster Tyen's world faces. Elsewhere, in an land ruled by the priests, Rielle the dyer's daughter has been taught that to use magic is to steal from the Angels. Yet she knows she has a talent for it, and that there is a corrupter in the city willing to teach her how to use it -- should she dare to risk the Angels' wrath.But not everything is as Tyen and Rielle have been raised to believe. Not the nature of magic, nor the laws of their lands... and not even the people they trust.

    A Discovery of Witches, Shadow of Night, and The Book of Life, now available in an eBook bundleWith more than a million copies sold in the United States, A Discovery of Witches and Shadow of Night have landed on all of the major bestseller lists, garnered rave reviews, and spellbound legions of loyal fans.The Book of Life brings the number one New York Times bestselling series to a deeply satisfying close, and we are now pleased to offer all three books in a lavishlydesigned boxed set, perfect for fans and newcomers alike.

    Sure, she's got telekinetic powers—a skill that the government is all too happy to make use of, sending her on secret break-in missions that no ordinary human could carry out. But all she really wants to do is kick back, have a beer, and pretend she's normal for once.But then a body turns up at the site of her last job—murdered in a way that only someone like Teagan could have pulled off. She's got 24 hours to clear her name—and it's not just her life at stake. If she can't unravel the conspiracy in time, her hometown of Los Angeles will be in the crosshairs of an underground battle that's on the brink of exploding... Full of imagination, wit and random sh*t flying through the air, this insane adventure from an irreverent new voice will blow your tiny mind.

    Now he makes the case that living on Mars is not just plausible, but inevitable.It sounds like science fiction, but Stephen Petranek considers it fact: Within twenty years, humans will live on Mars. We'll need to. In this sweeping, provocative book that mixes business, science, and human reporting, Petranek makes the case that living on Mars is an essential back-up plan for humanity and explains in fascinating detail just how it will happen.The race is on. Private companies, driven by iconoclastic entrepreneurs, such as Elon Musk, Jeff Bezos, Paul Allen, and Sir Richard Branson; Dutch reality show and space mission Mars One; NASA; and the Chinese government are among the many groups competing to plant the first stake on Mars and open the door for human habitation. Why go to Mars? Life on Mars has potential life-saving possibilities for everyone on earth. Depleting water supplies, overwhelming climate change, and a host of other disasters — from terrorist attacks to meteor strikes — all loom large. We must become a space-faring species to survive. We have the technology not only to get humans to Mars, but to convert Mars into another habitable planet. It will likely take 300 years to "terraform" Mars, as the jargon goes, but we can turn it into a veritable second Garden of Eden. And we can live there, in specially designed habitations, within the next twenty years.In this exciting chronicle, Petranek introduces the circus of lively characters all engaged in a dramatic effort to be the first to settle the Red Planet. How We'll Live on Mars brings firsthand reporting, interviews with key participants, and extensive research to bear on the question of how we can expect to see life on Mars within the next twenty years.