Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences. Key Features of the Sixth Edition Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners More than 1,200 high-quality, full-color illustrations A concise appendix reviewing important Organic Chemistry Concepts New to the Sixth Edition: Fully Updated with a significant revision of all chapters and major topics Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

    The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.New to This Edition The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.

    According to Llinas, the mindness state evolved to allow predictive interactions between mobile creatures and their environment. He illustrates the early evolution of mind through a primitive animal called the sea squirt. The mobile larval form has a brainlike ganglion that receives sensory information about the surrounding environment. As an adult, the sea squirt attaches itself to a stationary object then digests most of its own brain. This suggests that the nervous system evolved to allow active movement in animals. To move through the environment safely, a creature must anticipate the outcome of each movement on the basis of incoming sensory data. Thus the capacity to predict is most likely the ultimate brain function. One could even say that Self is the centralization of prediction.

    In Projections, he combines his groundbreaking access to the brain's inner circuitry with a deep empathy for his patients to examine what mental illness reveals about the mind and the origin of human feelings--how the broken can illuminate the unbroken. An internationally acclaimed professor of bioengineering and psychiatry at Stanford, Deisseroth's true passion is clinical psychiatry, and it is the stories of his patients that form the backbone of Projections. Through these case studies, he tells the larger story of how we can understand the physical and biological origins of human emotion in the brain. As such, he describes vividly how humans experience feelings both in the simple and ancient circuits of our brains and in the poignant moments of suffering in our daily lives. The stories of Deisseroth's patients are rich with humanity and shine an unprecedented light on the self and the ways in which it breaks down. A young woman with an eating disorder reveals how the mind can rebel against the brain's most primitive drives of hunger and thirst; while an older gentleman, smothered into silence by depression and dementia, illuminates how humans evolved to feel joy and its absence; and a lonely Uyghur woman far from home teaches the importance of rich social bonds. An illuminating and essential work, Projections transforms the way we understand the brain as a biological and as an emotional object.A groundbreaking tour of the human mind that illuminates the biological nature of our inner worlds and emotions, through gripping, moving—and, at times, harrowing—clinical stories“[A] scintillating and moving analysis of the human brain and emotions.”—Nature“Beautifully connects the inner feelings within all human beings to deep insights from modern psychiatry and neuroscience.”—Robert Lefkowitz, Nobel Laureate

    In late 2004, leading Western scientists joined the Dalai Lama at his home in Dharamsala, India, to address this very question–and in the process brought about a revolution in our understanding of the human mind. In this fascinating and far-reaching book, Wall Street Journal science writer Sharon Begley reports on how cutting-edge science and the ancient wisdom of Buddhism have come together to show how we all have the power to literally change our brains by changing our minds. These findings hold exciting implications for personal transformation.For decades, the conventional wisdom of neuroscience held that the hardware of the brain is fixed and immutable–that we are stuck with what we were born with. As Begley shows, however, recent pioneering experiments in neuroplasticity, a new science that investigates whether and how the brain can undergo wholesale change, reveal that the brain is capable not only of altering its structure but also of generating new neurons, even into old age. The brain can adapt, heal, renew itself after trauma, and compensate for disability. Begley documents how this fundamental paradigm shift is transforming both our understanding of the human mind and our approach to deep-seated emotional, cognitive, and behavioral problems. These breakthroughs show that it is possible to reset our happiness meter, regain the use of limbs disabled by stroke, train the mind to break cycles of depression and OCD, and reverse age-related changes in the brain. They also suggest that it is possible to teach and learn compassion, a key step in the Dalai Lama’s quest for a more peaceful world. But as we learn from studies performed on Buddhist monks, an important component in changing the brain is to tap the power of mind and, in particular, focused attention. This is the classic Buddhist practice of mindfulness, a technique that has become popular in the West and that is immediately available to everyone. With her extraordinary gift for making science accessible, meaningful, and compelling, Sharon Begley illuminates a profound shift in our understanding of how the brain and the mind interact. This tremendously hopeful book takes us to the leading edge of a revolution in what it means to be human.

    This edition retains the essence of the original, but has been updated with new features and integrated colour illustrations.

    The 5th edition has been completely updated and includes a Companion CD-ROM that contains animations, NCLEX(R) examination-style review questions, printable IV therapy and medication safety checklists, drug calculation problems, and convenient electronic calculators.A separate drug calculations section - Medications and Calculations - features 65 pages of math review and step-by-step instructions for dosage calculations using the four primary methods - basic formula, ratio and proportion, dimensional analysis, and fractional equation. Nursing Process sections relate nursing care to drug therapy. Each step of the nursing process includes concise actions for the plan of care in relation to treatment for selected drug prototypes.A chapter on Principles of Drug Administration features comprehensive coverage of the procedures for administering drugs. It addresses all routes of administration and various settings.Unit openers for drug therapy chapters include an illustrated overview of normal anatomy and physiology, giving readers the foundation for understanding how the drug works in that body system.Herbal Alert boxes highlight various herbal products and their interactions with drugs.More than 100 detailed Prototype Drug Charts list the following information: dosage, indication, contraindication, drug-lab-food interactions, pharmacokinetics, pharmacodynamics, therapeutic effects, side effects, and adverse reactions.Highlighted Client Teaching, Cultural Considerations, and Herbal Alerts are included in the Nursing Process sections to emphasize key implications for nurses.Client Teaching in the nursing process sections guide readers through instructions for teaching patients about medication, self-administration, dietary concerns, and side effects.Includes a separate Transcultural and Genetic Considerations chapter.Critical Thinking Case Studies and Study Questions at the end of each chapter present readers with a clinical scenario and several questions that reinforce key concepts and encourage critical thinking.A new chapter on substance abuse addresses this important aspect of the nurse's role in pharmacology. Preventing Medication Errors boxes draw attention to important safety considerations and present guidelines from the Institute for Safe Medication Practice (ISMP).Critical Thinking Case Study boxes provide clinical scenarios and questions to sharpen analytical and critical thinking skills.Now includes step-by-step instructions for dosage calculations using dimensional analysis.Web sites, organizations, and research database information are available at the end of clinical chapters for further review and research.The newest JCAHO guidelines for medication safety are applied throughout the text and the abbreviations appendix has been revised to reflect these updates.Includes a new Herb/Drug Interaction chart, as well as new sugar-free and alcohol-free drug lists.Features updated coverage of pain as the fifth vital sign.Look-alike/sound-alike drugs are highlighted throughout to promote safe drug administration.Includes a list of the 200 most frequently prescribed drugs.Electronic Resources boxes at the beginning of each chapter direct readers to additional learning activities available on the Companion CD and the Evolve website.

    Following an introduction to neural structure and function, all the key methods and procedures of cognitive neuroscience are explained, with a view to helping students understand how they can be used to shed light on the neural basis of cognition.The second part of the book goes on to present an up-to-date overview of the latest theories and findings in all the key topics in cognitive neuroscience, including vision, attention, memory, speech and language, numeracy, executive function and social and emotional behaviour. Throughout, case studies, newspaper reports and everyday examples are used to provide an easy way in to understanding the more challenging ideas that underpin the subject.In addition each chapter includes:Summaries of key terms and points Example essay questions to aid exam preparation Recommended further reading Feature boxes exploring interesting and popular questions and their implications for the subject.Written in an engaging style by a leading researcher in the field, this book will be invaluable as a core text for undergraduate modules in cognitive neuroscience. It can also be used as a key text on courses in cognition, cognitive neuropsychology or brain and behaviour. Those embarking on research will find it an invaluable starting point and reference.We offer CD-ROM-based resources free of charge to instructors who recommend The Student's Guide to Cognitive Neuroscience by Jamie Ward. These resources include:A chapter-by-chapter, illustrated slideshow lecture course An innovative bank of multiple-choice questions, graded according to difficulty and which allow for confidence-weighted answers Comprehensive lecture planning advice tailored to different length courses.Jamie Ward has researched and taught extensively in many areas of cognitive neuroscience. He is a leading authority on the subject of synaesthesia and has contributed to a wider understanding of it in both academic and lay circles.

    This book includes a companion CD-ROM that adds a visual emphasis with animations.

    Increasingly, science is concerned with the structure, behavior, and evolution of complex systems ranging from cells to ecosystems. In Networks of the Brain, Olaf Sporns describes how the integrative nature of brain function can be illuminated from a complex network perspective.Highlighting the many emerging points of contact between neuroscience and network science, the book serves to introduce network theory to neuroscientists and neuroscience to those working on theoretical network models. Sporns emphasizes how networks connect levels of organization in the brain and how they link structure to function, offering an informal and nonmathematical treatment of the subject. Networks of the Brain provides a synthesis of the sciences of complex networks and the brain that will be an essential foundation for future research.

    The thoroughly revised and updated 18th Edition is packed with essential information on diagnosing and treating medical disorders to help medical professionals deliver the best care to their patients. This handy, compact guide was written by a team of clinicians for everyday use. Designed for maximum clinical utility, the new Merck Manual of Diagnosis and Therapy makes it easy to find the right information, right when it is needed. It is a must-have for medical students, residents, practicing physicians, nurses, and allied health professionals.Featuring: All new "approach" chapters All-new abstract summaries 341 total chapters 34 completely new chapters 69 new illustrations New cross-referencing Two-color presentation Brand new content on: critical care medicine, metabolic syndrome, acute lung injury, biological warfare and terrorism, SARS, smallpox, and more

    A natural overachiever, Collins' success, in college and medical school led to a surgical residency at one of the most respected medical centers in the world, the famed Mayo Clinic. But compared to his fellow residents Collins feels inadequate and unprepared. All too soon, the euphoria of beginning his career as an orthopedic resident gives way to the feeling he is a counterfeit, an imposter who has infiltrated a society of brilliant surgeons.This story of Collins' four-year surgical residency traces his rise from an eager but clueless first-year resident to accomplished Chief Resident in his final year. With unparalleled humor, he recounts the disparity between people's perceptions of a doctor's glamorous life and the real thing: a succession of run down cars that are towed to the junk yard, long weekends moonlighting at rural hospitals, a family that grows larger every year, and a laughable income.Collins' good nature helps him over some of the rough spots but cannot spare him the harsh reality of a doctor's life. Every day he is confronted with decisions that will change people's lives-or end them-forever. A young boy's leg is mangled by a tractor: risk the boy's life to save his leg, or amputate immediately? A woman diagnosed with bone cancer injures her hip: go through a painful hip operation even though she has only months to live? Like a jolt to the system, he is faced with the reality of suffering and death as he struggles to reconcile his idealism and aspiration to heal with the recognition of his own limitations and imperfections.Unflinching and deeply engaging, Hot Lights, Cold Steel is a humane and passionate reminder that doctors are people too. This is a gripping memoir, at times devastating, others triumphant, but always compulsively readable.

    It combines a detailed textbook that emphasizes clinical and functional correlates of histology with a beautifully illustrated atlas featuring full-color digital micrographs of the highest quality.This edition includes over 100 new illustrations, more Clinical Correlation boxes on the histology of common medical conditions, and new information on the molecular biology of endothelial cell function. Terminology throughout the text is consistent with Terminologia Anatomica.A powerful interactive histology atlas CD-ROM for students is included with the book and features all of the plates found in the text with interactive functionality.

    Discusses the causes, symptoms, and treatment of attention-deficit Disorder (ADD).

    This new edition combines established features that have made this title a favorite with new features and updates.