They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    The illustrations provide some of the best quality and most varied examples of skin conditions important to any health care pforessional dealing with skin problems.

    In the third edition, all the chapters have been thoroughly revised and the concepts updated. A new chapter on the spectral analysis of heart rate variability has been added. This is the first textbook in medicine to introduce this topic as a text for medical students. Apart from this, the feedback received from students and teachers has been given due importance and is reflected in this edition.

    The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.New to This Edition The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.

    Why am I here? Is there a purpose to my life? What happens when I die? These deep questions are addressed with clear wisdom, vivid images and memorable stories.

    Robert Lesslie, whose routine faced him with times of grief or pain, relief or delight, life or death. Such everyday happenings and encounters gave rise to these vignettes—in which readers will meet up with the characters, coincidences, and complications common to the emergency room:characters like Freddy, who literally shoots himself in the footcoincidences like finally having the chance to hear what patients say to each other when doctors and nurses aren’t in the roomcomplications such as dealing with parents who buy lottery tickets and alcohol instead of medicine for their little boyThese heart-tugging, heart-lifting slices of life will prompt readers to search for opportunities to give the comfort of a touch, the grace of a kind word, or a prayer that brings hope and healing.

    Each case includes an extended discussion, definition of terms, clinical pearls, and USMLE format review questions. This interactive learning system is proven to improve shelf-exam scores and helps students to learn in the context of real patients insted of simply memorizing.

    This book reveals Ashwani’s time-tested and practical day trading strategies & systems which are easy to understand and implement: • The 3Ms of trading success — method, money management & mind-set • The technical pillars — moving averages, pivots & exceptional candles • Profitable trade entry, trade management & exit tactics • How to trade the morning range, trends, gaps, & sideways markets • How to add the catalyst of big news events to power your trades • How to avoid — and profit from — market traps • How to harness the explosive power of multiple trading tools working in tandem • Money management — position size & risk management • How to master your mind in order to vanquish the market • The daily discipline of a successful day trader. Packed with 200 real market examples & charts, this book shows you how to approach the market every single trading day like a winner, equipped with appropriate technical expertise and supreme self-confidence. ABOUT THE AUTHOR Ashwani Gujral is one of India’s most famous market analysts & trading experts. He is the Chief Market Strategist and Fund Manager of ashwanigujral.com and a regular market commentator including on CNBC TV18 business channel. He has written on trading & technical analysis for leading US specialist magazines and journals, including The Active Trader, Stock Futures and Options, Futures, Trader’s Source and Technical Analysis of Stocks and Commodities. Ashwani has been a full time trader of stocks and derivatives since 1995. His activities include running a technical analysis plus trading chatroom and newsletter. This is his third book.

    

    You will learn: Trading strategies that work in bull and bear markets Insider tricks used by professional traders Why option sellers have a huge advantage over option buyers High probability winning trading strategies How to make money using iron condors, spreads, and other strategies Join the thousands of smart traders who have come over to the "selling side."Now is the time to get started making money the easy way.And if you ever get stuck, you can always reach out to me by email (provided inside of the book), and I will help you. Get started today: Scroll back up to the top of this page and select the "Buy Now" button.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences. Key Features of the Sixth Edition Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners More than 1,200 high-quality, full-color illustrations A concise appendix reviewing important Organic Chemistry Concepts New to the Sixth Edition: Fully Updated with a significant revision of all chapters and major topics Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

    In this 148-page hardback they reveal the places that they have got to know and love and show you why Tokyo is the friendliest big city in the world. It’s a guide book that will lead you to the best in culture and new architecture – and a few fun nights out too.The Monocle Travel Guide series reveals our favourite places in each city we cover, from the ideal route for an early-morning run to the best spots for independent retail. Full of surprises and quirks, they also feature detailed design and architecture pages, neighbourhood walks to get you away from the crowds and our favourite places to eat everything be it tasty fast food or something truly celebratory.

    Zen Baggage is an account of that journey. He weaves together historical background, interviews with Zen masters, and translations of the earliest known records of Zen, along with personal vignettes. Porter’s account captures the transformations taking place at religious centers in China but also the abiding legacy they have somehow managed to preserve. Porter brings wisdom and humor to every situation, whether visiting ancient caves containing the most complete collection of Buddhist texts ever uncovered, enduring a six-hour Buddhist ceremony, searching in vain for the ghost in his room, waking up the monk in charge of martial arts at Shaolin Temple, or meeting the abbess of China’s first Zen nunnery. Porter’s previously published Road to Heaven: Encounters with Chinese Hermits has become recommended reading at Zen centers and universities throughout America and even in China (in its Chinese translation), and Zen Baggage is sure to follow suit.

    In Where There's a Will, Stephen M. Silverman shows just how different with a peek at the wills of the richest, most celebrated people of all time, and he provides the intimate scoop on what their heirs had to say about it. Discover what secret pact Clark Gable made in 1942 and took to his grave - only to be exposed when his will was read. Learn why it took more than a year for Liza Minnelli to raise the $37,500 needed to bury the ashes of her mother, Judy Garland, and what treasures were left to the heirs of Babe Ruth, James Dean, John Jacob Astor, Ernest Hemingway, and Ayn Rand once those wills cleared probate. From Marilyn Monroe and Andy Warhol to John Lennon, Jim Morrison, John Steinbeck, Rita Hayworth, and Jack Dempsey, Where There's a Will . . . is an utterly engrossing read sure to captivate tycoons and gossip addicts alike with its fascinating tales of how the other half bequeaths.