But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    What I did not anticipate was how my journey would also resonate with men.America knows Jane Fonda as actress and activist, feminist and wife, workout guru and role model. In this extraordinary memoir, Fonda shows that she is much more. From her youth among Hollywood’s elite to her film career and her activism today, Fonda reveals intimate details and personal truths she hopes can provide a lens through which others can see their lives and how they can live them a little differently. Surprising, candid, and wonderfully written, My Life So Far is filled with insights into the personal struggles of a woman living a remarkable life.

    . . a book that enriches our understanding of how the struggle to think new thoughts is shared across time and space and people.”—The Sunday Telegraph (London)Christmas, 1859. Just one month after the publication of On the Origin of Species, Charles Darwin received an unsettling letter. He had expected criticism; in fact, letters were arriving daily, most expressing outrage and accusations of heresy. But this letter was different. It accused him of failing to acknowledge his predecessors, of taking credit for a theory that had already been discovered by others. Darwin realized that he had made an error in omitting from Origin of Species any mention of his intellectual forebears. Yet when he tried to trace all of the natural philosophers who had laid the groundwork for his theory, he found that history had already forgotten many of them.Darwin’s Ghosts tells the story of the collective discovery of evolution, from Aristotle, walking the shores of Lesbos with his pupils, to Al-Jahiz, an Arab writer in the first century, from Leonardo da Vinci, searching for fossils in the mine shafts of the Tuscan hills, to Denis Diderot in Paris, exploring the origins of species while under the surveillance of the secret police, and the brilliant naturalists of the Jardin de Plantes, finding evidence for evolutionary change in the natural history collections stolen during the Napoleonic wars. Evolution was not discovered single-handedly, Rebecca Stott argues, contrary to what has become standard lore, but is an idea that emerged over many centuries, advanced by daring individuals across the globe who had the imagination to speculate on nature’s extraordinary ways, and who had the courage to articulate such speculations at a time when to do so was often considered heresy.With each chapter focusing on an early evolutionary thinker, Darwin’s Ghosts is a fascinating account of a diverse group of individuals who, despite the very real dangers of challenging a system in which everything was presumed to have been created perfectly by God, felt compelled to understand where we came from. Ultimately, Stott demonstrates, ideas—including evolution itself—evolve just as animals and plants do, by intermingling, toppling weaker notions, and developing over stretches of time. Darwin’s Ghosts presents a groundbreaking new theory of an idea that has changed our very understanding of who we are.

    That is until 1904, when the disease broke out in a household in Oyster Bay, Long Island. Authorities suspected the family cook, Mary Mallon, of being a carrier. But before she could be tested, the woman, soon to be known as Typhoid Mary, had disappeared. Over the course of the next three years, Mary worked at several residences, spreading her pestilence as she went. In 1907, she was traced to a home on Park Avenue, and taken into custody. Institutionalized at Riverside Hospital for three years, she was released only when she promised never to work as a cook again. She promptly disappeared.For the next five years Mary worked in homes and institutions in and around New York, often under assumed names. In February 1915, a devastating outbreak of typhoid at the Sloane Hospital for Women was traced to her. She was finally apprehended and reinstitutionalized at Riverside Hospital, where she would remain for the rest of her life.Typhoid Mary is the story of her infamous life. Anthony Bourdain reveals the seedier side of the early 1900s, and writes with his renowned panache about life in the kitchen, uncovering the horrifying conditions that allowed the deadly spread of typhoid over a decade. Typhoid Mary is a true feast for history lovers and Bourdain lovers alike.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind—from his brain to his fingertips to his abs.From the bestselling author of The Year of Living Biblically and The Know-It-All comes the true and truly hilarious story of one person’s quest to become the healthiest man in the world. Hospitalized with a freak case of tropical pneumonia, goaded by his wife telling him, “I don’t want to be a widow at forty-five,” and ashamed of a middle-aged body best described as “a python that swallowed a goat,” A.J. Jacobs felt compelled to change his ways and get healthy. And he didn’t want only to lose weight, or finish a triathlon, or lower his cholesterol. His ambitions were far greater: maximal health from head to toe. The task was epic. He consulted an army of experts— sleep consultants and sex clinicians, nutritionists and dermatologists. He subjected himself to dozens of different workouts—from Strollercize classes to Finger Fitness sessions, from bouldering with cavemen to a treadmill desk. And he took in a cartload of diets: raw foods, veganism, high protein, calorie restriction, extreme chewing, and dozens more. He bought gadgets and helmets, earphones and juicers. He poked and he pinched. He counted and he measured. The story of his transformation is not only brilliantly entertaining, but it just may be the healthiest book ever written. It will make you laugh until your sides split and endorphins flood your bloodstream. It will alter the contours of your brain, imprinting you with better habits of hygiene and diet. It will move you emotionally and get you moving physically in surprising ways. And it will give you occasion to reflect on the body’s many mysteries and the ultimate pursuit of health: a well-lived life.

    These pieces are not a metaphor. They are actual pieces. Twenty years after the publication of her iconic Shutterbabe, we remeet Deborah Copaken at her darkly comedic nadir: battered, broke, divorcing, dissected, and dying—literally—on sexism’s battlefield as she deliriously scoops up what she believes to be her internal organs, which have fallen out of her body, into a glass Tupperware container before heading off to the hospital for emergency surgery . . . in an UberPool.Part cri de coeur cautionary tale, part dystopian tragicomedy, Ladyparts is Copaken’s irreverent inventory of both the female body and the body politic of womanhood in America. With her journalist’s eye, her novelist’s heart, and her performer’s sense of timing, she provides a frontline account of one woman brought to her knees by the one-two-twelve punch of divorce, solo motherhood, lack of healthcare, unaffordable childcare, shady landlords, her father’s death, college tuitions, sexual harassment, corporate indifference, ageism, sexism, and just plain old bad luck. Plus seven serious illnesses, one on top of the other, which provide the book’s narrative skeleton: vagina, uterus, breast, heart, cervix, brain, and lungs. She keeps bouncing back from each bum body part and finding the black humor in every setback, but in her slippery struggle to survive a steep plunge off the middle-class ladder, she is suddenly awoken to what it means to have no safety net.Turning her Harlem home into a commune to pay rent and have childcare, she trades her life as a bestselling novelist to apply for full-time corporate gigs that come with health insurance but often not scruples. She gets fired from a health magazine for being unhealthy; laid off from a PR firm for rushing home to deal with a child’s medical emergency; and sexually harassed out of her newspaper column, only to be grilled by the FBI when her harasser is offered a plum job in the White House.Side-splittingly funny one minute, a freak horror show the next, and quintessentially American, Ladyparts is an era-defining memoir for our time.

    The authors bring to life Darwin's reckless student days in Cambridge, his epic five-year voyage on the Beagle, and his grueling struggle to develop his theory of evolution.Adrian Desmond and James Moore's gripping narrative reveals the great personal cost to Darwin of pursuing inflammatory truths—telling the whole story of how he came to his epoch-making conclusions.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    The Lady and Her Monsters by Roseanne Motillo brings to life the fascinating times, startling science, and real-life horrors behind Mary Shelley’s gothic masterpiece, Frankenstein.Montillo recounts how—at the intersection of the Romantic Age and the Industrial Revolution—Shelley’s Victor Frankenstein was inspired by actual scientists of the period: curious and daring iconoclasts who were obsessed with the inner workings of the human body and how it might be reanimated after death.With true-life tales of grave robbers, ghoulish experiments, and the ultimate in macabre research—human reanimation—The Lady and Her Monsters is a brilliant exploration of the creation of Frankenstein, Mary Shelley’s horror classic.

    Interviews with a Guatemalan national leader discuss her country's political situation and the resulting violence, which has claimed the lives of her brother, mother, and father.

    Now, on the 150th anniversary of its publication, acclaimed science writer and master of narrative nonfiction Bill Hayes has written the fascinating, never-before-told true story of how this seminal volume came to be. A blend of history, science, culture, and Hayes’s own personal experiences, The Anatomist is this author’s most accomplished and affecting work to date.With passion and wit, Hayes explores the significance of Gray’s Anatomy and explains why it came to symbolize a turning point in medical history. But he does much, much more. Uncovering a treasure trove of forgotten letters and diaries, he illuminates the astonishing relationship between the fiercely gifted young anatomist Henry Gray and his younger collaborator H. V. Carter, whose exquisite anatomical illustrations are masterpieces of art and close observation. Tracing the triumphs and tragedies of these two extraordinary men, Hayes brings an equally extraordinary era–the mid 1800s–unforgettably to life.But the journey Hayes takes us on is not only outward but inward–through the blood and tissue and organs of the human body–for The Anatomist chronicles Hayes’s year as a student of classical gross anatomy, performing with his own hands the dissections and examinations detailed by Henry Gray 150 years ago. As Hayes’s acquaintance with death deepens, he finds his understanding and appreciation of life deepening in unexpected and profoundly moving ways. The Anatomist is more than just the story of a book. It is the story of the human body, a story whose beginning and end we all know and share but that, like all great stories, is infinitely rich in between.

    Nestled in the Appalachian mountains, Owsley County is one of the poorest counties in both Kentucky and the country. Buildings are crumbling and fields sit vacant, as tobacco farming and coal mining decline. But strong women are finding creative ways to subsist in their hollers in the hills. Cassie Chambers grew up in these hollers and, through the women who raised her, she traces her own path out of and back into the Kentucky mountains. Chambers’s Granny was a child bride who rose before dawn every morning to raise seven children. Despite her poverty, she wouldn’t hesitate to give the last bite of pie or vegetables from her garden to a struggling neighbor. Her two daughters took very different paths: strong-willed Ruth—the hardest-working tobacco farmer in the county—stayed on the family farm, while spirited Wilma—the sixth child—became the first in the family to graduate from high school, then moved an hour away for college. Married at nineteen and pregnant with Cassie a few months later, Wilma beat the odds to finish school. She raised her daughter to think she could move mountains, like the ones that kept her safe but also isolated her from the larger world. Cassie would spend much of her childhood with Granny and Ruth in the hills of Owsley County, both while Wilma was in college and after. With her “hill women” values guiding her, Cassie went on to graduate from Harvard Law. But while the Ivy League gave her knowledge and opportunities, its privileged world felt far from her reality, and she moved back home to help her fellow rural Kentucky women by providing free legal services. Appalachian women face issues that are all too common: domestic violence, the opioid crisis, a world that seems more divided by the day. But they are also community leaders, keeping their towns together in the face of a system that continually fails them. With nuance and heart, Chambers uses these women’s stories paired with her own journey to break down the myth of the hillbilly and illuminate a region whose poor communities, especially women, can lead it into the future.

    By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.