But AIDS is just one of the many emerging viruses for which we have, as yet, no cure. Even the old plagues – TB, cholera, bubonic plague – are making a comeback, resistant now to our drugs.Frank Ryan, a leading authority on disease, describes the groundbreaking research of the world’s leading experts in the field to show both where these viruses come from and why they prove to be so lethal, and advances a radical new biological theory for the origins and behaviour of plague viruses. Full of vivid despatches from the front line of research and medicine, 'Virus X' is terrifying and essential reading for anyone interested in the effects of plague viruses on human evolution.“Extremely well written…Frank Ryan has the page-turning and spine-chilling ability of a good novelist”MATT RIDLEY, 'Sunday Telegraph'“Compelling and frightening…the plot could not be bettered”MICHAEL SMITH, 'Scotsman'“Ryan is very good at making technical matters comprehensible to the lay reader but more impressive still is the way he conveys the intellectual excitement and elation of scientific discovery”ANTHONY DANIELS, 'Literary Review'“Ryan takes us through the drama of discovery and challenges the notion that certain questions are too appalling to contemplate”DAVID BRADLEY, 'New Scientist'“Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives…very readable and disturbing”JOHN R.G. TURNER, 'New York Times'

    In Ten Arguments For Deleting Your Social Media Accounts Right Now Jaron Lanier draws on his insider's expertise to explain precisely how social media works and why its cruel and dangerous effects are at the heart of its current business model and design. As well as offering ten simple arguments for liberating yourself from its addictive hold, his witty and urgent manifesto outlines a vision for an alternative that provides all the benefits of social media without the harm. nicer person in the process.

    Anti-Gerasone halts the aging process and prevents people from dying of old age as long as they keep taking it; as a result, America now suffers from severe overpopulation and shortages of food and resources. With the exception of the very wealthy, most of the population appears to survive on a diet of foods made from processed seaweed and sawdust. Gramps Ford, his chin resting on his hands, his hands on the crook of his cane, was staring irascibly at the five-foot television screen that dominated the room. On the screen, a news commentator was summarizing the day's happenings. Every thirty seconds or so, Gramps would jab the floor with his cane-tip and shout, "Hell, we did that a hundred years ago!" Emerald and Lou, coming in from the balcony, where they had been seeking that 2185 A.D. rarity--privacy--were obliged to take seats in the back row, behind about a dozen relatives with whom they shared the house. All save Gramps, who was somewhat withered and bent, seemed, by pre-anti-gerasone standards, to be about the same age--somewhere in their late twenties or early thirties. Gramps looked older because he had already reached 70 when anti-gerasone was invented. He had not aged in the 102 years since. "Next one shoots off his big bazoo while the TV's on is gonna find hisself cut off without a dollar--" his voice suddenly softened and sweetened--"when they wave that checkered flag at the Indianapolis Speedway, and old Gramps gets ready for the Big Trip Up Yonder." He sniffed sentimentally, while his heirs concentrated desperately on not making the slightest sound. For them, the poignancy of the prospective Big Trip had been dulled somewhat, through having been mentioned by Gramps about once a day for fifty years.

    . . and then broke? How would you survive? Could you improve on humanity's original timeline? And how hard would it be to domesticate a giant wombat? With this book as your guide, you'll survive--and thrive--in any period in Earth's history. Bestselling author and time-travel enthusiast Ryan North shows you how to invent all the modern conveniences we take for granted--from first principles. This illustrated manual contains all the science, engineering, art, philosophy, facts, and figures required for even the most clueless time traveler to build a civilization from the ground up. Deeply researched, irreverent, and significantly more fun than being eaten by a saber-toothed tiger, How to Invent Everything will make you smarter, more competent, and completely prepared to become the most important and influential person ever.

    Robots have descended on us from outer space, escaped from top-secret laboratories, and even traveled back in time to destroy us.Today, scientists are working hard to bring these artificial creations to life. In Japan, fuzzy little real robots are delivering much appreciated hug therapy to the elderly. Children are frolicking with smiling robot toys.It all seems so innocuous. And yet how could so many Hollywood scripts be wrong?So take no chances. Arm yourself with expert knowledge. For the sake of humanity, listen to serious advice from real robotics experts. How else will you survive the inevitable future in which robots rebel against their human masters?

    In Self Comes to Mind, he goes against the long-standing idea that consciousness is somehow separate from the body, presenting compelling new scientific evidence that consciousness—what we think of as a mind with a self—is to begin with a biological process created by a living organism. Besides the three traditional perspectives used to study the mind (the introspective, the behavioral, and the neurological), Damasio introduces an evolutionary perspective that entails a radical change in the way the history of conscious minds is viewed and told. He also advances a radical hypothesis regarding the origins and varieties of feelings, which is central to his framework for the biological construction of consciousness: feelings are grounded in a near fusion of body and brain networks, and first emerge from the historically old and humble brain stem rather than from the modern cerebral cortex.  Damasio suggests that the brain’s development of a human self becomes a challenge to nature’s indifference and opens the way for the appearance of culture, a radical break in the course of evolution and the source of a new level of life regulation—sociocultural homeostasis. He leaves no doubt that the blueprint for the work-in-progress he calls sociocultural homeostasis is the genetically well-established basic homeostasis, the curator of value that has been present in simple life-forms for billions of years. Self Comes to Mind is a groundbreaking journey into the neurobiological foundations of mind and self.Downloadhttp://depositfiles.com/files/xlt08paxhOrhttp://www.filesonic.com/file/3554828...

    Mankind is reengineering the planet, investing up to ten trillion dollars per year in transportation, energy, and communications infrastructure linking the world’s burgeoning megacities together. This has profound consequences for geopolitics, economics, demographics, the environment, and social identity. Connectivity, not geography, is our destiny. In Connectography, visionary strategist Parag Khanna travels from Ukraine to Iran, Mongolia to North Korea, Pakistan to Nigeria, and across the Arctic Circle and the South China Sea to explain the rapid and unprecedented changes affecting every part of the planet. He shows how militaries are deployed to protect supply chains as much as borders, and how nations are less at war over territory than engaged in tugs-of-war over pipelines, railways, shipping lanes, and Internet cables. The new arms race is to connect to the most markets—a race China is now winning, having launched a wave of infrastructure investments to unite Eurasia around its new Silk Roads. The United States can only regain ground by fusing with its neighbors into a super-continental North American Union of shared resources and prosperity.Connectography offers a unique and hopeful vision for the future. Khanna argues that new energy discoveries and technologies have eliminated the need for resource wars; ambitious transport corridors and power grids are unscrambling Africa’s fraught colonial borders; even the Arab world is evolving a more peaceful map as it builds resource and trade routes across its war-torn landscape. At the same time, thriving hubs such as Singapore and Dubai are injecting dynamism into young and heavily populated regions, cyber-communities empower commerce across vast distances, and the world’s ballooning financial assets are being wisely invested into building an inclusive global society. Beneath the chaos of a world that appears to be falling apart is a new foundation of connectivity pulling it together.Advance praise for Connectography“Connectography is ahead of the curve in seeing the battlefield of the future and the new kind of tug-of-war being waged on it. Khanna’s scholarship and foresight are world-class. . . . A must-read for the next president.”—Chuck Hagel, former U.S. secretary of defense “This bold reframing is an exciting addition to our ongoing debate about geopolitics and the future of globalization.”—Dominic Barton, global managing partner, McKinsey & Company “This is probably the most global book ever written. It is intensely specific while remaining broad and wide. Its takeaway is that infrastructure is destiny: Follow the supply lines outlined in this book to see where the future flows.”—Kevin Kelly, co-founder, Wired “There’s no better guide than Khanna to show us all the possibilities of this new hyperconnected world.”—Mathew Burrows, director, Strategic Foresight Initiative at the Atlantic Council, and former counselor, U.S. National Intelligence Council “This book is an invaluable resource for anyone involved in business, science, arts, or any other field.”—Mark Mobius, executive chairman, Templeton Emerging Markets Group “A must-read for anyone who wants to understand the future of humanity.”—Sandy Pentland, professor, MIT Media Lab

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    But at what cost? In this urgent and revelatory excavation of our Information Age, leading technology thinker Adam Greenfield forces us to reconsider our relationship with the networked objects, services and spaces that define us. It is time to re-evaluate the Silicon Valley consensus determining the future.We already depend on the smartphone to navigate every aspect of our existence. We're told that innovations--from augmented-reality interfaces and virtual assistants to autonomous delivery drones and self-driving cars--will make life easier, more convenient and more productive. 3D printing promises unprecedented control over the form and distribution of matter, while the blockchain stands to revolutionize everything from the recording and exchange of value to the way we organize the mundane realities of the day to day. And, all the while, fiendishly complex algorithms are operating quietly in the background, reshaping the economy, transforming the fundamental terms of our politics and even redefining what it means to be human.Having successfully colonized everyday life, these radical technologies are now conditioning the choices available to us in the years to come. How do they work? What challenges do they present to us, as individuals and societies? Who benefits from their adoption? In answering these questions, Greenfield's timely guide clarifies the scale and nature of the crisis we now confront --and offers ways to reclaim our stake in the future.

    About three quarters of the jobs created in the United States since the great recession pay only a bit more than minimum wage. Still, the United States has more millionaires and billionaires than any country ever, and we continue to mint them.In this eye-opening book, renowned economist and bestselling author Tyler Cowen explains that phenomenon: High earners are taking ever more advantage of machine intelligence in data analysis and achieving ever-better results. Meanwhile, low earners who haven’t committed to learning, to making the most of new technologies, have poor prospects. Nearly every business sector relies less and less on manual labor, and this fact is forever changing the world of work and wages. A steady, secure life somewhere in the middle—average—is over.With The Great Stagnation, Cowen explained why median wages stagnated over the last four decades; in Average Is Over he reveals the essential nature of the new economy, identifies the best path forward for workers and entrepreneurs, and provides readers with actionable advice to make the most of the new economic landscape. It is a challenging and sober must-read but ultimately exciting, good news. In debates about our nation’s economic future, it will be impossible to ignore.

    Angier takes readers on a mesmerizing tour of female anatomy and physiology that explores everything from organs to orgasm, and delves into topics such as exercise, menopause, and the mysterious properties of breast milk.A self-proclaimed "scientific fantasia of womanhood." Woman ultimately challenges widely accepted Darwinian-based gender stereotypes. Angier shows how cultural biases have influenced research in evolutionary psychology (the study of the biological bases of behavior) and consequently led to dubious conclusions about "female nature." such as the idea that women are innately monogamous while men are natural philanderers.But Angier doesn't just point fingers; she offers optimistic alternatives and transcends feminist polemics with an enlightened subversiveness that makes for a joyful, fresh vision of womanhood. Woman is a seminal work that will endure as an essential read for anyone intersted in how biology affects who we are as women, as men, and as human beings.

    In fact, AI will dramatically change our entire society.You might have heard that many jobs will be replaced by automation and robots, but did you also know that at the same time a huge number of new jobs will be created by AI?This book covers many fascinating and timely topics related to artificial intelligence, including: self-driving cars, robots, chatbots, and how AI will impact the job market, business processes, and entire industries, just to name a few.This book is divided into ten chapters:Chapter I: Introduction to Artificial IntelligenceChapter II: How Artificial Intelligence Is Changing Many IndustriesChapter III: How Artificial Intelligence Is Changing Business ProcessesChapter IV: Chatbots and How They Will Change CommunicationChapter V: How Artificial Intelligence Is Changing the Job MarketChapter VI: Self-Driving Cars and How They Will Change Traffic as We Know ItChapter VII: Robots and How They Will Change Our LivesChapter VIII: Artificial Intelligence Activities of Big Technology CompaniesChapter IX: Frequently Asked Questions About Artificial Intelligence Part IChapter X: Frequently Asked Questions About Artificial Intelligence Part IITo enhance your learning experience and help make the concepts easier to understand, there are more than 85 visual presentations included throughout the book.You will learn the answers to 101 questions about artificial intelligence, and also have access to a large number of resources, ideas and tips that will help you to understand how artificial intelligence will change our lives.Who is this book for?Managers and business professionalsMarketers and influencersEntrepreneurs and startupsConsultants and coachesEducators and teachersStudents and life-long learnersAnd everyone else who is interested in our future.Are you ready to discover how artificial intelligence will impact your life This guidebook offers a multitude of tools, techniques and strategies that every business and individual can quickly apply and benefit from.

    “Big data” refers to our burgeoning ability to crunch vast collections of information, analyze it instantly, and draw sometimes profoundly surprising conclusions from it. This emerging science can translate myriad phenomena—from the price of airline tickets to the text of millions of books—into searchable form, and uses our increasing computing power to unearth epiphanies that we never could have seen before. A revolution on par with the Internet or perhaps even the printing press, big data will change the way we think about business, health, politics, education, and innovation in the years to come. It also poses fresh threats, from the inevitable end of privacy as we know it to the prospect of being penalized for things we haven’t even done yet, based on big data’s ability to predict our future behavior.In this brilliantly clear, often surprising work, two leading experts explain what big data is, how it will change our lives, and what we can do to protect ourselves from its hazards. Big Data is the first big book about the next big thing.www.big-data-book.com

    'A focused snapshot of a brave new world.' - Nature In 2018 the world woke up to gene editing with a storm of controversy over twin girls born in China with genetic changes deliberately introduced by scientists – changes they will pass on to their own offspring. Genetic modification (GM) has been with us for 45 years now, but the new system known as CRISPR or gene editing can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago. But is it ethical to change the genetic material of organisms in a way that might be passed on to future generations? If a person is suffering from a lethal genetic disease, is it unethical to deny them this option? Who controls the application of this technology, when it makes ‘biohacking’ – perhaps of one’s own genome – a real possibility?Nessa Carey’s book is a thrilling and timely snapshot of a cutting-edge technology that will radically alter our futures and the way we prevent disease.

    Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction.When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.