The Tell-Tale Brain: A Neuroscientist's Quest for What Makes Us Human


V.S. Ramachandran - 2011
    S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

The Brain that Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science


Norman Doidge - 2007
    Psychiatrist and psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they’ve transformed - people whose mental limitations or brain damage were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.

Synaptic Self: How Our Brains Become Who We Are


Joseph E. LeDoux - 2002
    In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.

Incognito: The Secret Lives of the Brain


David Eagleman - 2011
    If the conscious mind—the part you consider you—accounts for only a tiny fraction of the brain’s function, what is all the rest doing? This is the question that David Eagleman—renowned neuroscientist and acclaimed author of Sum—answers in a book as accessible and entertaining as it is deeply informed by startling, up-to-the-minute research.

The Mind and the Brain: Neuroplasticity and the Power of Mental Force


Jeffrey M. Schwartz - 2001
    Now in paperback, Dr Jeffrey Schwartz and Sharon Begley's groundbreaking work, The Mind and the Brain, argues exactly the opposite: that the mind has a life of its own.Dr Schwartz, a leading researcher in brain dysfunctions, and Wall Street Journal science columnist Sharon Begley demonstrate that the human mind is an independent entity that can shape and control the functioning of the physical brain. Their work has its basis in our emerging understanding of adult neuroplasticity–the brain's ability to be rewired not just in childhood, but throughout life, a trait only recently established by neuroscientists.Through decades of work treating patients with obsessive–compulsive disorder (OCD), Schwartz made an extraordinary finding: while following the therapy he developed, his patients were effecting significant and lasting changes in their own neural pathways. It was a scientific first: by actively focusing their attention away from negative behaviors and toward more positive ones, Schwartz's patients were using their minds to reshape their brains–and discovering a thrilling new dimension to the concept of neuroplasticity.The Mind and the Brain follows Schwartz as he investigates this newly discovered power, which he calls self–directed neuroplasticity or, more simply, mental force. It describes his work with noted physicist Henry Stapp and connects the concept of 'mental force' with the ancient practice of mindfulness in Buddhist tradition. And it points to potential new applications that could transform the treatment of almost every variety of neurological dysfunction, from dyslexia to stroke–and could lead to new strategies to help us harness our mental powers. Yet as wondrous as these implications are, perhaps even more important is the philosophical dimension of Schwartz's work. For the existence of mental force offers convincing scientific evidence of human free will, and thus of man's inherent capacity for moral choice.

Musicophilia: Tales of Music and the Brain


Oliver Sacks - 2007
    In Musicophilia, he shows us a variety of what he calls “musical misalignments.” Among them: a man struck by lightning who suddenly desires to become a pianist at the age of forty-two; an entire group of children with Williams syndrome, who are hypermusical from birth; people with “amusia,” to whom a symphony sounds like the clattering of pots and pans; and a man whose memory spans only seven seconds-for everything but music. Illuminating, inspiring, and utterly unforgettable, Musicophilia is Oliver Sacks’ latest masterpiece.

The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and Will Determine the Fate of the Human Race


Daniel Z. Lieberman - 2018
    In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it’s why we gamble and squander. From dopamine’s point of view, it’s not the having that matters. It’s getting something—anything—that’s new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion – and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

How the Mind Works


Steven Pinker - 1997
    He explains what the mind is, how it evolved, and how it allows us to see, think, feel, laugh, interact, enjoy the arts, and ponder the mysteries of life. And he does it with the wit that prompted Mark Ridley to write in the New York Times Book Review, "No other science writer makes me laugh so much. . . . [Pinker] deserves the superlatives that are lavished on him."  The arguments in the book are as bold as its title. Pinker rehabilitates some unfashionable ideas, such as that the mind is a computer and that human nature was shaped by natural selection, and challenges fashionable ones, such as that passionate emotions are irrational, that parents socialize their children, and that nature is good and modern society corrupting. Winner of the Los Angeles Times Book Prize A New York Times Notable Book of the Year and Publishers Weekly Best Book of 1997 Featured in Time magazine, the New York Times Magazine, The New Yorker, Nature, Science, Lingua Franca, and Science Times Front-page reviews in the Washington Post Book World, the Boston Globe Book Section, and the San Diego Union Book Review

Mapping the Mind


Rita Carter - 1998
    We can actually observe a person's brain registering a joke or experiencing a painful memory. Drawing on the latest imaging technology and the expertise of distinguished scientists, Rita Carter explores the geography of the human brain. Her writing is clear, accessible, witty, and the book's 150 illustrations—most in color—present an illustrated guide to that wondrous, coconut-sized, wrinkled gray mass we carry inside our heads.Mapping the Mind charts the way human behavior and culture have been molded by the landscape of the brain. Carter shows how our personalities reflect the biological mechanisms underlying thought and emotion and how behavioral eccentricities may be traced to abnormalities in an individual brain. Obsessions and compulsions seem to be caused by a stuck neural switch in a region that monitors the environment for danger. Addictions stem from dysfunction in the brain's reward system. Even the sense of religious experience has been linked to activity in a certain brain region. The differences between men and women's brains, the question of a "gay brain," and conditions such as dyslexia, autism, and mania are also explored.Looking inside the brain, writes Carter, we see that actions follow from our perceptions, which are due to brain activity dictated by a neuronal structure formed from the interplay between our genes and the environment. Without sidestepping the question of free will, Carter suggests that future generations will use our increasing knowledge of the brain to "enhance those mental qualities that give sweetness and meaning to our lives, and to eradicate those that are destructive."

Behave: The Biology of Humans at Our Best and Worst


Robert M. Sapolsky - 2017
    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

Descartes' Error: Emotion, Reason and the Human Brain


António R. Damásio - 1994
    Even modern neuroscience has tended, until recently, to concentrate on the cognitive aspects of brain function, disregarding emotions. This attitude began to change with the publication of Descartes’ Error in 1995. Antonio Damasio—"one of the world’s leading neurologists" (The New York Times)—challenged traditional ideas about the connection between emotions and rationality. In this wondrously engaging book, Damasio takes the reader on a journey of scientific discovery through a series of case studies, demonstrating what many of us have long suspected: emotions are not a luxury, they are essential to rational thinking and to normal social behavior.

Connectome: How the Brain's Wiring Makes Us Who We Are


Sebastian Seung - 2012
    Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture.Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen.In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality.Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience.

Human: The Science Behind What Makes Us Unique


Michael S. Gazzaniga - 2008
    What it has not done is consider the stark reality that most of the time we humans are thinking about social processes, comparing ourselves to and estimating the intentions of others. In Human, Gazzaniga explores a number of related issues, including what makes human brains unique, the importance of language and art in defining the human condition, the nature of human consciousness, and even artificial intelligence.

This Is Your Brain on Music: The Science of a Human Obsession


Daniel J. Levitin - 2006
    Why does music evoke such powerful moods? The answers are at last be- coming clear, thanks to revolutionary neuroscience and the emerging field of evolutionary psychology. Both a cutting-edge study and a tribute to the beauty of music itself, This Is Your Brain on Music unravels a host of mysteries that affect everything from pop culture to our understanding of human nature, including: • Are our musical preferences shaped in utero? • Is there a cutoff point for acquiring new tastes in music? • What do PET scans and MRIs reveal about the brain’s response to music? • Is musical pleasure different from other kinds of pleasure?This Is Your Brain on Music explores cultures in which singing is considered an essential human function, patients who have a rare disorder that prevents them from making sense of music, and scientists studying why two people may not have the same definition of pitch. At every turn, this provocative work unlocks deep secrets about how nature and nurture forge a uniquely human obsession.

The Other Brain: From Dementia to Schizophrenia, How New Discoveries about the Brain Are Revolutionizing Medicine and Science


R. Douglas Fields - 2008
    The Other Brain is the story of glia, which make up approximately 85 percent of the cells in the brain. Long neglected as little more than cerebral packing material ("glia" means glue), glia are sparking a revolution in brain science.Glia are completely different from neurons, the brain cells that we are familiar with. Scientists are discovering that glia have their own communication network, which operates in parallel to the more familiar communication among neurons. Glia provide the insulation for the neurons, and glia even regulate the flow of information between neurons.But it is the potential breakthroughs for medical science that are the most exciting frontier in glia research today. Diseases such as brain cancer and multiple sclerosis are caused by diseased glia. Glia are now believed to play an important role in such psychiatric illnesses as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson's and Alzheimer's. They are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. Scientists have discovered that glia repair the brain and spinal cord after injury and stroke. The more we learn about these cells that make up the "other" brain, the more important they seem to be.Written by a neuroscientist who is a leader in the research to reveal the secrets of these brain cells, The Other Brain offers a firsthand account of science in action. It takes us into the laboratories where important discoveries are being made, and it explains how scientists are learning that glial cells come in different types, with different capabilities. It tells the story of glia research from its origins to the most recent discoveries and gives readers a much more complete understanding of how the brain works and where the next breakthroughs in brain science and medicine are likely to come.