That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

    A number of studies show a link between vitamin K2, bone health and heart health. Is vitamin K2 a nutrient you need more of in your diet? As physicians, we feel everyone needs to be aware of the role this vitamin plays in health and wellness. This concise ebook explores the link between vitamin K2 and how it may protect against some of the most common diseases you’re at risk for as you age. Here are some of the questions this book will answer: The Role of Vitamin K in Your Body How Vitamin K2 Differs from Vitamin K1 and Why Most People Don’t Get Enough of It The Various Isoforms of Vitamin K2 and Which Ones Are Most Important for Health The Role Vitamin K2 Plays in Bone Health and Osteoporosis Prevention Vitamin K2 and Heart Disease: Can It Lower Your Risk or Even Reverse Atherosclerosis? Do You Need a Vitamin K2 Supplement? Vitamin K2 and Cancer: Is There a Link? The Role Vitamin K2 Plays in Dental Health Are You at Risk for Vitamin K Deficiency? Can You Get Enough Vitamin K2 Through Diet Alone? The Best Dietary Source of Vitamin K2 Why You Must Have Vitamin K2 if You Take a Vitamin D Supplement Are There Risks to Taking a Vitamin K2 Supplement? One Type of Vitamin K2 Supplement Source You Should Avoid You should have a better understanding of the health benefits of vitamin K2 once you finish.

    Most arrive safely and go home with their families in a matter of days. But not all babies come into the world healthy and almost half a million arrive well before they are expected. These newborns need tiny medicine. Told from the first-person perspective, Dr. Chris DeRienzo—a neonatologist, health system leader and frequent keynote speaker—walks readers through the human experience of caring for the world's smallest and sickest patients. His stories share the absurd and the sublime parts of being a doctor and detail how they have shaped who he is as a husband, father, and person. Readers will learn the secrets of the NICU, the loneliness that comes with life and death decisions, and the incredibly powerful sense of purpose and triumph that comes with just making it through the night and keeping everyone alive. In the end, this book delivers an insider's view of a doctor's life never before accessible without a white coat.

    It is the story of two nurses who witnessed the early years of the HIV/AIDS epidemic from the frontline. It focuses on their lives and their experiences. Some of the story is raw, sometimes graphic, but familiar for people with HIV infection, family members, friends, and other nurses and medical professionals such as Ellen and Valery. There were hundreds of nurses who went through what Ellen and Valery experienced. They want to tell this story to give a voice to a generation lost, encouraging the world to remember one simple thing: this history cannot be repeated.

    When there aren’t enough of them, or they aren’t working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine’s Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they’re the wave of the future. “Neil takes readers on a riveting journey through the past, present and future of stem cell therapy. His well-researched, educational and entertaining book could change your life. I highly recommend it.” Tony Robbins, NY Times #1 Bestselling Author 100 years old will soon become the new 60. Stem cells are a key therapeutic to enable this future. Dr. Riordan’s book is your guide to why this is true and how you will benefit. A must read for anyone who cares about extending their healthy lifespan.” Peter H. Diamandis, MD; Founder, XPRIZE & Singularity University; Co-Founder, Human Longevity, Inc.; Author of NY Times Best Sellers Abundance and Bold

    Should they follow cautionary guidelines to return to a major city or take a chance by continuing north through the back country?Thru-hiking from Georgia to Maine on any given year has its own enormous obstacles. What do you eat? Where do you sleep and can you reach your family? In 2020, during a worldwide shutdown these challenges became nearly impossible to overcome. See how rural trail town communities were affected by the pandemic and understand an untold perspective of pursuing your dreams at all costs.Avoiding law enforcement, entering into "closed" federal land and even overcoming death - all while attempting the impossible. With a wife and two daughters at home, the outside world against him and seemingly unreliable information, this epic tale follows Ryan Michael Beck's journey 2,193 miles in pursuit of a dream to thru-hike the entire Appalachian Trail against all odds.

    Unlocking the secrets of our genomes opens the door to understanding why we are the way we are and potentially fixing what ails us, from cancer and diabetes to obesity and male pattern baldness. But what exactly will happen to this information? Will it be a boon or just another marketing tool?Here Is a Human Being is the first in-depth look at personal genomics—its larger-than-life research subjects; its entrepreneurs and do-it-yourselfers; its technology developers; and the bewildered physicians and regulators who must negotiate with it—and what it means to be a “public genome” in a world where privacy is already under siege.

     A distraught woman who regrets not going to see a GP sooner. More Googled self-diagnoses than one can count… After three years as one of London’s doctors - as full-time night-time GP doing the house calls that no-one else wants to do - Alex Rudd has switched to working in surgeries. Rudd travels to a different place surgery each day, helping those struggling to cope with patient numbers and seeing those that might not otherwise be seen. With limited time to spend on each patient, he must walk the difficult line between caring for patients while diagnosing and prescribing efficiently. Hilarious diagnoses mix with genuine tragedies as Rudd sees a variety of patients, with all sorts of medical conditions. In this follow-up to “London Call-Out: Confessions of a Doctor in the Capital”, Rudd presents us with another window into the world of the freelance GP today, and the challenges they face. With moments that stir admiration and sadness, this timely and insightful memoir is as thought-provoking as it is entertaining.

    You will rethink your entire perspective on the healthcare industry and their providers after reading this book. “Do yourself a favor and never give in to someone telling you that you need to smell something in the medical field.” -Nugget of wisdom from a trauma nurse. There is a lot about the healthcare industry and the medical profession, especially the workers that keep it functional that is unknown and shrouded in secrecy. If you’ve ever wondered how they deal with the things they’ve seen that will probably make you throw up your last meal and all the ones before that, then this book is for you. In Confessions of a Trauma Nurse, Arayah Sunshine gives a unique and rare peek into the daily activities of professionals in the healthcare industry with a fresh perspective never seen elsewhere or written down in this manner. Not for the weak-minded, this book gives a different spin on the realities of the medical profession. Taken from trauma nurses from different backgrounds with stories and anecdotes that will make you laugh, cringe-inducing horror stories, moments that will make you indignant and others that will bring you near tears, this book will take you on an emotional, yet insightful and enlightening roller coaster. Confessions of a Trauma Nurse is chock-full of lots of captivating thoughts, ideas, and comments that border deliciously on the edge of very dark humor. Some are as little as a sentence long, yet pack a punch so powerful that you will be thinking about them for hours, if not days. It also contains tips from the “pros” to avoid falling for the tricks and traps that healthcare providers set for themselves! But beware, once you’ve begun reading, you will not want to put this one down for even a minute, so make sure you’ve cleared your schedule for the day before delving into the psyche of trauma nurses. You might also want to make sure you can handle gross moments because this book contains a lot. If you’re a healthcare provider, then this is definitely a book you should add to your shelf. If you’re interested in the daily activities and thought processes of healthcare providers and trauma nurses, get this book. Scroll up and click the buy button now to get your copy of Confessions of a Trauma Nurse by Arayah Sunshine and get started on your way into the world of healthcare providers!

    Between the foolish and sometimes silly calls she goes on, are the heart-pounding serious cases that make every EMT anxious. And somehow, she still has time for a love life.

    

    Margaret I. Cuomo is inspired to seek out new strategies for waging a smarter war on cancer.This year, about 1.6 million new cases of cancer will be diagnosed and more than 1,500 people will die "per day." We've been asked to accept the disappointing strategy to "manage cancer as a chronic disease." We've allowed pharmaceutical companies to position cancer drugs that extend life by just weeks and may cost $100,000 for a single course of treatment as breakthroughs. Where is the bold leadership that will transform our system from treatment to prevention? Have we forgotten the mission of the National Cancer Act of 1971 to "conquer cancer"?Through an analysis of more than 40 years of medical evidence and interviews with the top cancer researchers, drug company executives, and health policy advisers, Dr. Cuomo reveals intriguing answers to these questions. She shows us how all cancer stakeholders--the pharmaceutical industry, the government, physicians, and concerned Americans--can change the way we view and fight cancer in this country.