The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    senator, in January 2005, and served as the chief official White House photographer for the President's full two terms. Souza was with President Obama more often, and at more crucial moments, than any friend or staff member, or even the First Lady--and he photographed it all. Souza captured nearly 2 million photographs of Obama, in moments ranging from classified to disarmingly candid.This large-format (12"x10"), exquisitely produced book presents more than 300 of Souza's favorite and most iconic images from these historic years; many have never been seen before. This seminal work on the Obama presidency documents moments of national importance--including the historic image of the President and his advisors watching tensely in the Situation Room as the Bin Laden mission unfolded--alongside unguarded moments with the President's family, his many encounters with children, and his time spent interacting with world leaders, members of Congress, White House staff, artists, musicians and more.The photographs are paired with captions and stories providing behind-the-scenes context for each, and offer insight into the special relationship Souza and the President forged during their time together. The result is a stunning record of a landmark era in American history.Souza's work enabled us to feel that we knew the President. This book puts us in the White House with him.

    In Musicophilia, he shows us a variety of what he calls “musical misalignments.” Among them: a man struck by lightning who suddenly desires to become a pianist at the age of forty-two; an entire group of children with Williams syndrome, who are hypermusical from birth; people with “amusia,” to whom a symphony sounds like the clattering of pots and pans; and a man whose memory spans only seven seconds-for everything but music. Illuminating, inspiring, and utterly unforgettable, Musicophilia is Oliver Sacks’ latest masterpiece.

    Like when doctors prescribed morphine for crying infants. When snorting skull moss was a cure for a bloody nose. When consuming mail-order tapeworms was a latter-day fad diet. Or when snake oil salesmen peddled strychnine (used in rat poison) as an aphrodisiac in the '60s. Seamlessly combining macabre humor with hard science and compelling storytelling, Quackery is a visually rich and information-packed exploration of history's most outlandish cures, experiments, and scams.A humorous book that delves into some of the wacky but true ways that humans have looked to cure their ills. Leeches, mercury, strychnine, and lobotomies are a few of the topics that explore the lengths society has gone in the search for health.

    Every day she tries to bring care and comfort to those reaching the end of their lives and to help make dying more bearable. Rachel's training was put to the test in 2017 when her beloved GP father was diagnosed with terminal cancer. She learned that nothing - even the best palliative care - can sugar-coat the pain of losing someone you love. And yet, she argues, in a hospice there is more of what matters in life - more love, more strength, more kindness, more joy, more tenderness, more grace, more compassion - than you could ever imagine. For if there is a difference between people who know they are dying and the rest of us, it is simply this: that the terminally ill know their time is running out, while we live as though we have all the time in the world. Dear Life is a book about the vital importance of human connection, by the doctor we would all want by our sides at a time of crisis. It is a love letter - to a father, to a profession, to life itself.

    When first published in 1969, this study was described by the Guardian as …as exciting and readable an account as you could wish." This new edition of the major study on the subject is illustrated by over seventy contemporary black and white illustrations and eight pages of color.A series of natural disasters in the furthest reaches of the Orient during the third of the fourteenth century heralded what was, for the population of Europe, the most devastating period of death and destruction in its history. By the autumn of 1347 the Black Death had reached the shores of the eastern Mediterranean, and the years that followed were to witness a horrifying and apparently relentless epidemic.One third of England's population died between the years 1347 and 1350, and over one thousand villages were deserted, never to be repopulated. In towns and cities the cemeteries were unable to provide space for all the dead, and violence and crime spiraled. Travel became dangerous and interruption of food and other supplies across the country added hunger and deprivation to the problems of people already overwhelmed by the threat of the vilest of deaths. In the countryside the population was halved in places, and as land became plentiful, landowners' profits fell and the government tried in vain to fix labourers' wages and prices, peasant unrest accelerated and the manorial system disintegrated, culminating eventually in the Peasants' Revolt of 1381. Throughout Europe whole societies were disrupted; racial tensions built as a direct result of the plague, and persecution of Jews began in earnest throughout the continent. The social and economic consequences of the period were to reach far into the following century.

    Armed with the extraordinary new discoveries about our genes, Ridley turns his attention to the nature versus nurture debate to bring the first popular account of the roots of human behaviour. What makes us who we are?In February 2001 it was announced that the genome contains not 100,000 genes as originally expected but only 30,000. This startling revision led some scientists to conclude that there are simply not enough human genes to account for all the different ways people behave: we must be made by nurture, not nature.Matt Ridley argues that the emerging truth is far more interesting than this myth. Nurture depends on genes, too, and genes need nurture. Genes not only predetermine the broad structure of the brain; they also absorb formative experiences, react to social cues and even run memory. They are consequences as well as causes of the will.Published fifty years after the discovery of the double helix of DNA, Nature via Nurture chronicles a new revolution in our understanding of genes. Ridley recounts the hundred years' war between the partisans of nature and nurture to explain how this paradoxical creature, the human being, can be simultaneously free-willed and motivated by instinct and culture. Nature via Nurture is an enthralling, up-to-the-minute account of how genes build brains to absorb experience.

    These black-and-white and vibrantly colored images, many resembling abstract art, are employed daily by scientists around the world, but most have never before been seen by the general public. Each chapter addresses a different set of techniques for studying the brain as revealed through the images, and each is introduced by a leading scientist in that field of study. Author Carl Schoonover’s captions provide detailed explanations of each image as well as the major insights gained by scientists over the course of the past 20 years. Accessible to a wide audience, this book reveals the elegant methods applied to study the mind, giving readers a peek at its innermost workings, helping us to understand them, and offering clues about what may lie ahead. Praise for Portraits of the Mind: "An odyssey through the brain, illuminated by a rainbow" --New York Times "Stunning images" --Scientific American "The collection of images in the new book Portraits of the Mind is truly impressive . . . The mix of history, science and art is terrific." -Wired.com "History, science, and art come together to provide a unique perspective on what's going on upstairs." --New Yorker.com "No knowledge of the source or subject matter of these images is necessary; the book is justified by their beauty alone." --Science "A remarkable new book"- -Discover.com "John Keats's insistence that truth is beauty is exemplified by Carl Schoonover's wonderful book Portraits of the Mind. Since one cannot understand the present without examining the past, this book offers a delightful and instructive way of accomplishing just that. I enthusiastically recommend this beautiful book both to students of brain science and to lovers of art." -Eric R. Kandel, MD, Nobel Prize in Physiology or Medicine, 2000; University Professor at Columbia; Fred Kavli Professor and Director, Kavli Institute for Brain Science; Senior Investigator at the Howard Hughes Medical Institute; and author of In Search of Memory: The Emergence of a New Science of Mind "Portraits of the Mind achieves a rare combination of beauty and knowledge. Its images of the brain are mesmerizing, from medieval engravings to modern visualizations as gorgeously abstract as anything by Rothko or de Kooning. And in explaining the nature of these images, this book also delivers an enlightening, up-to-date history of neuroscience." -Carl Zimmer, author of Soul Made Flesh: The Discovery of the Brain-and How It Changed the World and The Mind's Eye Goes Blind: Fifteen Journeys Through the Brain "Portraits of the Mind is a remarkable book that combines beautifully reproduced illustrations of the nervous system as it has been visualized over the centuries, as well as lively and authoritative commentaries by some of today's leading neuroscientists. It will be enjoyed by professionals and general readers alike." --Dale Purves, MD, Professor of Neurobiology, Psychology and Neuroscience; and Philosophy at Duke University

    This excursion into the history of bizarre entertainments includes armless calligraphers, mathematical dogs, tightrope-walking fleas and assorted quacks, flimflammers and charlatans of spectacle.

    Dr. Wecht takes the reader inside some of the nation's most bizarre and intriguing medico-legal investigations and shows how forensic scientists help to solve crimes, and why they sometimes fail in their efforts. His vast experience and his willingness to take on the establishment if necessary and provide proof that runs counter to popular opinion make this book a page-turner.

    Saag, MD, an internationally known expert on the virus that causes AIDS, but the book is more than a memoir: through his story, Dr. Saag also shines a light on the dysfunctional US healthcare system, proposing optimistic yet realistic remedies drawn from his distinguished medical career.Mike Saag began his medical residency in 1981, within days of the Centers for Disease Control’s first report of a mysterious “gay cancer” killing young men. Soon, the young doctor’s career was yoked to the epidemic. His life’s work became turning the most deadly virus in human history into a chronic, manageable disease.In the lab at the University of Alabama at Birmingham, Dr. Saag and colleagues made seminal early discoveries about the elusive virus. And at the AIDS clinic he founded, Dr. Saag met people whose fight against a virtual death sentence touched his heart and inspired him to work even harder. As his career stretched across three decades, Dr. Saag found himself battling another foe, this one almost as pernicious as AIDS itself: a broken healthcare system shaped more by politicians, insurers, and lobbyists than by patients’ needs.Positive is Dr. Saag’s tribute to the unforgettable patients he has known and an urgent call to create a comprehensive, compassionate, accessible healthcare system in the name of those we can save today.

    Fantasy took over his life, in a world of battles ruled by his teddy bear, Alan Measles. He grew up. And in 2003, an acclaimed ceramic artist, he accepted the Turner Prize as his alter-ego Clare, wearing his best dress, with a bow in his hair. Now he tells his own story, his voice beautifully caught by his friend, the writer Wendy Jones. Early childhood in Chelmsford, Essex is a rural Eden that ends abruptly with the arrival of his stepfather, leading to constant swerving between his parents' houses, and between boys' and women's clothes. But as Grayson enters art college and discovers the world of London squats and New Romanticism, he starts to find himself. At last he steps out as a potter and transvestite.

    Days later, the madman was dead and Denis was framed for murder. A riveting exposé of the fierce debates, deadly politics, and cutthroat rivalries behind the first transfusion experiments, Blood Work takes us from dissection rooms in palaces to the streets of Paris, providing an unforgettable portrait of an era that wrestled with the same questions about morality and experimentation that haunt medical science today.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.

    A down-and-out sausage-casing worker by day who turned surplus animal intestines into a million-dollar condom enterprise at night; inventors who fashioned cervical caps out of watch springs; and a mother of six who kissed photographs of the inventor of the Pill -- these are just a few of the individuals who make up this riveting story.