These black-and-white and vibrantly colored images, many resembling abstract art, are employed daily by scientists around the world, but most have never before been seen by the general public. Each chapter addresses a different set of techniques for studying the brain as revealed through the images, and each is introduced by a leading scientist in that field of study. Author Carl Schoonover’s captions provide detailed explanations of each image as well as the major insights gained by scientists over the course of the past 20 years. Accessible to a wide audience, this book reveals the elegant methods applied to study the mind, giving readers a peek at its innermost workings, helping us to understand them, and offering clues about what may lie ahead. Praise for Portraits of the Mind: "An odyssey through the brain, illuminated by a rainbow" --New York Times "Stunning images" --Scientific American "The collection of images in the new book Portraits of the Mind is truly impressive . . . The mix of history, science and art is terrific." -Wired.com "History, science, and art come together to provide a unique perspective on what's going on upstairs." --New Yorker.com "No knowledge of the source or subject matter of these images is necessary; the book is justified by their beauty alone." --Science "A remarkable new book"- -Discover.com "John Keats's insistence that truth is beauty is exemplified by Carl Schoonover's wonderful book Portraits of the Mind. Since one cannot understand the present without examining the past, this book offers a delightful and instructive way of accomplishing just that. I enthusiastically recommend this beautiful book both to students of brain science and to lovers of art." -Eric R. Kandel, MD, Nobel Prize in Physiology or Medicine, 2000; University Professor at Columbia; Fred Kavli Professor and Director, Kavli Institute for Brain Science; Senior Investigator at the Howard Hughes Medical Institute; and author of In Search of Memory: The Emergence of a New Science of Mind "Portraits of the Mind achieves a rare combination of beauty and knowledge. Its images of the brain are mesmerizing, from medieval engravings to modern visualizations as gorgeously abstract as anything by Rothko or de Kooning. And in explaining the nature of these images, this book also delivers an enlightening, up-to-date history of neuroscience." -Carl Zimmer, author of Soul Made Flesh: The Discovery of the Brain-and How It Changed the World and The Mind's Eye Goes Blind: Fifteen Journeys Through the Brain "Portraits of the Mind is a remarkable book that combines beautifully reproduced illustrations of the nervous system as it has been visualized over the centuries, as well as lively and authoritative commentaries by some of today's leading neuroscientists. It will be enjoyed by professionals and general readers alike." --Dale Purves, MD, Professor of Neurobiology, Psychology and Neuroscience; and Philosophy at Duke University

    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    Acclaimed writer Charles Schaar Murray's Boogie Man is the authorized and authoritative biography of this musician whose extraordinary career spanned over fifty years and included over one-hundred albums and five Grammy Awards. Murray was given unparalleled access to Hooker, and lets him tell his own story in his own words, from life in the Deep South to San Francisco, from the 1948 blues anthem "Boogie Chillen" to the Grammy-winning album The Healer nearly a half-century later. Boogie Man is far more than merely a brilliant biography of one man; it also gives the story of the music that inspired him. "When I die," Hooker said, they'll bury the blues with me. But the blues will never die." Here is the book that does him and his music full justice.

    Sympathetic yet balanced, Michael White's Isaac Newton offers a revelatory picture of Newton as a genius who stood at the point in history where magic ended and science began.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    Thus, the literature on speciation, as well as the number of researchers and students working in this area, has grown explosively. Despite thesedevelopments, there has been no book-length treatment of speciation in many years. As a result, both the seasoned scholar and the newcomer to evolutionary biology had no ready guide to the recent literature on speciation--a body of work that is enormous, scattered, and increasingly technical.Although several excellent symposium volumes have recently appeared, these collections do not provide a unified, critical, and up-to-date overview of the field. Speciation is designed to fill this gap.Aimed at professional biologists, graduate students, and advanced undergraduates, Speciation covers both plants and animals (the first book on this subject to do so), and deals with all relevant areas of research, including biogeography, field work, systematics, theory, and genetic and molecularstudies. It gives special emphasis to topics that are either controversial or the subject of active research, including sympatric speciation, reinforcement, the role of hybridization in speciation, the search for genes causing reproductive isolation, and mounting evidence for the role of natural andsexual selection in the origin of species. The authors do not hesitate to take stands on these and other controversial issues. This critical and scholarly book will be invaluable to researchers in evolutionary biology and is also ideal for a graduate-level course on speciation.

    But AIDS is just one of the many emerging viruses for which we have, as yet, no cure. Even the old plagues – TB, cholera, bubonic plague – are making a comeback, resistant now to our drugs.Frank Ryan, a leading authority on disease, describes the groundbreaking research of the world’s leading experts in the field to show both where these viruses come from and why they prove to be so lethal, and advances a radical new biological theory for the origins and behaviour of plague viruses. Full of vivid despatches from the front line of research and medicine, 'Virus X' is terrifying and essential reading for anyone interested in the effects of plague viruses on human evolution.“Extremely well written…Frank Ryan has the page-turning and spine-chilling ability of a good novelist”MATT RIDLEY, 'Sunday Telegraph'“Compelling and frightening…the plot could not be bettered”MICHAEL SMITH, 'Scotsman'“Ryan is very good at making technical matters comprehensible to the lay reader but more impressive still is the way he conveys the intellectual excitement and elation of scientific discovery”ANTHONY DANIELS, 'Literary Review'“Ryan takes us through the drama of discovery and challenges the notion that certain questions are too appalling to contemplate”DAVID BRADLEY, 'New Scientist'“Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives…very readable and disturbing”JOHN R.G. TURNER, 'New York Times'

    Throughout this fascinating book, Clifford Pickover invites us to share in the amazing adventures of brilliant, quirky, and passionate people after whom these laws are named. These lawgivers turn out to be a fascinating, diverse, and sometimes eccentric group of people. Many were extremely versatile polymaths--human dynamos with a seemingly infinite supply of curiosity and energy and who worked in many different areas in science. Others had non-conventional educations and displayed their unusual talents from an early age. Some experienced resistance to their ideas, causing significant personal anguish. Pickover examines more than 40 great laws, providing brief and cogent introductions to the science behind the laws as well as engaging biographies of such scientists as Newton, Faraday, Ohm, Curie, and Planck. Throughout, he includes fascinating, little-known tidbits relating to the law or lawgiver, and he provides cross-references to other laws or equations mentioned in the book. For several entries, he includes simple numerical examples and solved problems so that readers can have a hands-on understanding of the application of the law. A sweeping survey of scientific discovery as well as an intriguing portrait gallery of some of the greatest minds in history, this superb volume will engage everyone interested in science and the physical world or in the dazzling creativity of these brilliant thinkers.

    When he was in fourth grade, he even had to drop out of school and work to help his poor family make ends meet. Read all about how the man we know as the famous young chocolatier finally struck it rich -- in money, love, and chocolate!

    But in a world full of poisons, there was also an urgent practical need to name and recognize different plants, because most medicines were made from plant extracts.Anna Pavord takes us on a thrilling adventure into botanical history, traveling from Athens in the third century BC, through Constantinople, Venice, the medical school at Salerno to the universities of Pisa and Padua. The journey, traced here for the first time, involves the culture of Islam, the first expeditions to the Indies and the first settlers in the New World.In Athens, Aristotle's pupil Theophrastus was the first man ever to write a book about plants. How can we name, sort, and order them? He asked. The debate continues still, two thousand years later. Sumptuously illustrated in full colour, The Naming of Names gives a compelling insight into a world full of intrigue and intensely competitive egos.

    "100 Women Who Changed the World" takes kids on a tour of the past and uncovers the stories of the women and girls who have shaped the modern world.From intelligent innovators like Marie Curie and Rosalind Franklin to clever creatives like Emily Dickinson and J.K. Rowling to leading ladies like Joan of Arc and Eleanor Roosevelt, profiles explore the lives of each woman in detail, and photography and quirky "bobble-head" illustrations present history in a new and fun way. Kids can put each woman's story into context with "what came before " and "what came after " panels showing the things that influenced and were influenced by each woman. Special features highlight contemporaneous women and women in similar fields to paint a more complete picture for young readers.A wonderful inspiration for young girls and a great learning tool for all children, "100 Women Who Changed the World" proves that this isn't just a man's world."

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.