The Angel and the Assassin: The Tiny Brain Cell That Changed the Course of Medicine


Donna Jackson Nakazawa - 2020
    But a recent groundbreaking discovery revealed them to be capable of terrifying Jekyll and Hyde behavior. When triggered--and anything that stirs up the immune system in the body can activate microglia--they can morph into destroyers, impacting a wide range of issues from memory problems and anxiety to depression and Alzheimer's. Under the right circumstances, however, microglia can be coaxed back into being angelic healers, able to repair the brain in ways that help alleviate symptoms and hold the promise to one day prevent disease.A fascinating behind-the-scenes account of this cutting-edge science, The Angel and the Assassin also explores the medical implications of these game-changing discoveries. Award-winning journalist Donna Jackson Nakazawa began her investigation with a personal interest--when diagnosed with an autoimmune disorder years ago, she was convinced there was something physical going on in her brain as well as her body, though no doctor she consulted could explain how the two could be interacting in this way. With the compassion born of her own experience, she follows practitioners and patients on the front lines of treatments that help to "reboot" microglia--from neurofeedback and intermittent fasting to transcranial magnetic stimulation and gamma light flicker therapy. She witnesses patients finding significant relief from pressing symptoms--and at least one stunning recovery--offering new hope to the tens of millions who suffer from mental, cognitive, and physical health issues.Proving once and for all the biological basis for the mind-body connection, the discovery of the true role of microglia stands to rewrite psychiatric and medical texts as we know them. Hailed as "riveting," "stunning," and "visionary," The Angel and the Assassin offers us a radically reconceived picture of human health and promises to change everything we thought we knew about how to heal ourselves.

Memoirs of an Addicted Brain: A Neuroscientist Examines his Former Life on Drugs


Marc Lewis - 2011
    This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?"The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception.Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

Saving Normal: An Insider's Revolt Against Out-Of-Control Psychiatric Diagnosis, DSM-5, Big Pharma, and the Medicalization of Ordinary Life


Allen Frances - 2013
    The DSM is the bible of psychiatry; the go-to place to find out who is sick and who is not. Because it will radically stretch the boundaries of what is and what is not a psychiatric illness, DSM 5 will dramatically change how lives are lived. Under DSM 5's new definitions, millions of people now considered normal will be diagnosed as mentally ill, causing unnecessary, costly, and sometimes dangerous treatments for misidentified 'patients' who don't really need them.Will the DSM 5 destroy what is considered normal?Frances argues that DSM 5 offers a radical and reckless set of proposals that will overnight turn 'normal' people into 'mental patients'. Everyday aches, pains, disappointments, stresses, and existential sufferings are being reframed as mental illnesses with such exuberance that it is getting hard for anyone to get through life without a psychiatric diagnosis. Is grief a useful, inevitable and poignant sign of a broken heart or is it Major Depressive Disorder? Are temper tantrums a normal part of childhood or a sign of mental illness? Are you nervous about an upcoming presentation or job interview or do you have Mixed Anxiety Depression? If you don't remember a face or a fact once in a while, do you have Dementia?Frances maintains we all have psychiatric symptoms from time to time, but this doesn't mean we are all flirting with mental illness. Whenever we arbitrarily add a new 'disease', we subtract from what previously was 'normal' and lose something of ourselves in the process. Not all human suffering can or should be labeled and treated away. The grief and sorrows, the stresses, the disappointments, the aches and pains, the slings and arrows, the innate and acquired inequalities, the set-backs, the stumbles, the emotional gut-shots; this is part of life and of living in a complex and not always fair society- they should not all to be explained away as psychiatric disease.

Stop Walking on Eggshells: Taking Your Life Back When Someone You Care about Has Borderline Personality Disorder


Paul T. Mason - 1998
    It is designed to help them understand how the disorder affects their loved ones and recognize what they can do to get off the emotional roller coasters and take care of themselves.

Eccentrics: A Study of Sanity and Strangeness


David Weeks - 1995
    Ann Atkin keeps 7,500 garden gnomes in her backyard. Brooklyn artist Peter McGough dresses and acts as if it were 1895. These are just a few of the eccentrics discussed by Dr. Weeks, the world's foremost expert on the subject.

The Worm at the Core: On the Role of Death in Life


Sheldon Solomon - 2015
    In 1974, cultural anthropologist Ernest Becker won the Pulitzer Prize for his book The Denial of Death, arguing that the terror of death has a pervasive effect on human affairs. Now authors Sheldon Solomon, Jeff Greenberg, and Tom Pyszczynski clarify with wide-ranging evidence the many ways the worm at the core guides our thoughts and actions, from the great art we create to the devastating wars we wage. The Worm at the Core is the product of twenty-five years of in-depth research. Drawing from innovative experiments conducted around the globe, Solomon, Greenberg, and Pyszczynski show conclusively that the fear of death and the desire to transcend it inspire us to buy expensive cars, crave fame, put our health at risk, and disguise our animal nature. The fear of death can also prompt judges to dole out harsher punishments, make children react negatively to people different from themselves, and inflame intolerance and violence.   But the worm at the core need not consume us. Emerging from their research is a unique and compelling approach to these deeply existential issues: terror management theory. TMT proposes that human culture infuses our lives with order, stability, significance, and purpose, and these anchors enable us to function moment to moment without becoming overwhelmed by the knowledge of our ultimate fate.

The Dark Side of the Mind: True Stories from My Life as a Forensic Psychologist


Kerry Daynes - 2019
    The job: to delve into the psyche of convicted men and women to try to understand what lies behind their often brutal actions. Follow in the footsteps of Kerry Daynes, one of the most sought-after forensic psychologists in the business and consultant on major police investigations. Kerry's job has taken her to the cells of maximum-security prisons, police interview rooms, the wards of secure hospitals and the witness box of the court room. Her work has helped solve a cold case, convict the guilty and prevent a vicious attack. Spending every moment of your life staring into the darker side of life comes with a price. Kerry's frank memoir gives an unforgettable insight into the personal and professional dangers in store for a female psychologist working with some of the most disturbing men and women.

Imbeciles: The Supreme Court, American Eugenics, and the Sterilization of Carrie Buck


Adam Cohen - 2016
    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

The Psychopath Whisperer: The Science of Those Without Conscience


Kent A. Kiehl - 2014
    As Dr. Kent Kiehl shows, psychopaths can be identified by a checklist of symptoms that includes pathological lying; lack of empathy, guilt, and remorse; grandiose sense of self-worth; manipulation; and failure to accept one’s actions. But why do psychopaths behave the way they do? Is it the result of their environment— how they were raised—or is there a genetic compo­nent to their lack of conscience? This is the question Kiehl, a protégé of famed psychopath researcher Dr. Robert Hare, was deter­mined to answer as he began his career twenty years ago. To aid in his quest to unravel the psy­chopathic mind, Kiehl created the first mobile functional MRI scanner to study psychopaths in prison populations. The brains of more than five hundred psychopaths and three thousand other offenders have been scanned by Kiehl’s labora­tory—the world’s largest forensic neuroscience repository of its kind. Over the course of The Psy­chopath Whisperer, we follow the scientific bread crumbs that Kiehl uncovered to show that the key brain structures that correspond with emotional engagement and reactions are diminished in psy­chopaths, offering new clues to how to predict and treat the disorder. In The Psychopath Whisperer, Kiehl describes in fascinating detail his years working with psy­chopaths and studying their thought processes— from the remorseless serial killers he meets with behind bars to children whose behavior and per­sonality traits exhibit the early warning signs of psychopathy. Less than 1 percent of the general population meets the criteria for psychopathy. But psycho­paths account for a vastly outsized proportion of violent crimes. And as Kiehl shows, many who aren’t psychopaths exhibit some of the behaviors and traits associated with the condition. What do you do if you discover your roommate, or boss, or the person you are dating has traits that define a psy­chopath? And what does having a diminished limbic region of the brain mean for how the legal system approaches crimes committed by psychopaths? A compelling narrative of cutting-edge science, The Psychopath Whisperer will open your eyes on a fascinating but little understood world, with startling implications for society, the law, and our personal lives.

Insane: America's Criminal Treatment of Mental Illness


Alisa Roth - 2018
    Jails in New York, Los Angeles, and Chicago each house more people with mental illnesses than any hospital. As many as half of all people in America's jails and prisons have a psychiatric disorder. One in four fatal police shootings involves a person with such disorders.In this revelatory book, journalist Alisa Roth goes deep inside the criminal justice system to show how and why it has become a warehouse where inmates are denied proper treatment, abused, and punished in ways that make them sicker.Through intimate stories of people in the system and those trying to fix it, Roth reveals the hidden forces behind this crisis and suggests how a fairer and more humane approach might look. Insane is a galvanizing wake-up call for criminal justice reformers and anyone concerned about the plight of our most vulnerable.

Proust and the Squid: The Story and Science of the Reading Brain


Maryanne Wolf - 2007
    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.

Supernatural: Meetings with the Ancient Teachers of Mankind


Graham Hancock - 2005
    Then, in a dramatic change, described by scientists as 'the greatest riddle in human history', all the skills & qualities that we value most highly in ourselves appeared already fully formed, as tho bestowed on us by hidden powers. In Supernatural Hancock sets out to investigate this mysterious before-&-after moment & to discover the truth about the influences that gave birth to the modern mind. His quest takes him on a detective journey from the beautiful painted caves of prehistoric France, Spain & Italy to rock shelters in the mountains of S. Africa, where he finds extraordinary Stone Age art. He uncovers clues that lead him to the Amazon rainforest to drink the hallucinogen Ayahuasca with shamans, whose paintings contain images of 'super-natural beings' identical to the animal-human hybrids depicted in prehistoric caves. Hallucinogens such as mescaline also produce visionary encounters with exactly the same beings. Scientists at the cutting edge of consciousness research have begun to consider the possibility that such hallucinations may be real perceptions of other dimensions. Could the supernaturals 1st depicted in the painted caves be the ancient teachers of humankind? Could it be that human evolution isn't just the meaningless process Darwin identified, but something more purposive & intelligent that we've barely begun to understand?AcknowledgementsPart 1: Visions 1: Plant that enables men to see the dead 2: Greatest riddle of archeology 3: Vine of souls Part 2: Caves 4: Therianthropy5: Riddles of the caves6: Shabby academy 7: Searching for a Rosetta Stone8: Code in the mind 9: Serpents of the Drakensberg10: Wounded healer Part 3: Beings 11: Voyage into the supernatural 12: Shamans in the sky 13: Spirit love 14: Secret commonwealth15: Here is a thing that will carry me away16: Dancers between worlds Part 4: Codes 17: Turning in to channel DMT18: Amongst the machine elves19: Ancient teachers in our DNA?20: Hurricane in the junkyard Part 5: Religions 21: Hidden Shamans22: Flesh of the GodsPart 6: Mysteries 23: Doors leading to another world Appendices Critics & criticisms of David Lewis-Williams' Neuropsychological theory of rock & cave artPsilocybe semilanceata-a hallucinogenic mushroom native to Europe / Roy Watlng Interview with Rick StrassmanReferences Index

The Body in Pain: The Making and Unmaking of the World


Elaine Scarry - 1985
    The book is an analysis of physical suffering and its relation to the numerous vocabularies and cultural forces--literary, political, philosophical, medical, religious--that confront it. Elaine Scarry bases her study on a wide range of sources: literature and art, medical case histories, documents on torture compiled by Amnesty International, legal transcripts of personal injury trials, and military and strategic writings by such figures as Clausewitz, Churchill, Liddell Hart, and Kissinger, She weaves these into her discussion with an eloquence, humanity, and insight that recall the writings of Hannah Arendt and Jean-Paul Sartre. Scarry begins with the fact of pain's inexpressibility. Not only is physical pain enormously difficult to describe in words--confronted with it, Virginia Woolf once noted, "language runs dry"--it also actively destroys language, reducing sufferers in the most extreme instances to an inarticulate state of cries and moans. Scarry analyzes the political ramifications of deliberately inflicted pain, specifically in the cases of torture and warfare, and shows how to be fictive. From these actions of "unmaking" Scarry turns finally to the actions of "making"--the examples of artistic and cultural creation that work against pain and the debased uses that are made of it. Challenging and inventive, The Body in Pain is landmark work that promises to spark widespread debate.

The Female Malady: Women, Madness and English Culture 1830-1980


Elaine Showalter - 1985
    A vital counter-interpretation of madness in women, showing how it is often a consequence of, rather than a deviation from, the traditional female role.

A First-Rate Madness: Uncovering the Links Between Leadership and Mental Illness


S. Nassir Ghaemi - 2011
    By combining analysis of the historical evidence with the latest psychiatric research, Ghaemi demonstrates how he thinks these qualities have produced brilliant leadership under the toughest circumstances.individuals and society at large-however high the price for those who endure these illnesses.