But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    Lisa Seachrist Chiu has a smorgasbord of stories to tell about rare and not so rare genetic quirks. We read about the Dracula Gene, a mutation in zebra fish that causes blood cells to explode on contact with light, and suites of genes that also influence behavior and physical characteristics; the Tangier Island Gene, first discovered after physicians discovered a boy with orange tonsils (scientists now realize that the child's odd condition comes from an inability to process cholesterol); and Wilson's Disease, a gene defect that fails to clear copper from the body, which can trigger schizophrenia and other neurological symptoms, and can be fatal if left untreated. Friendlier mutations include the Myostatin gene, which allows muscles to become much larger than usual and enhances strength and the much-envied Cheeseburger Gene, which allows a lucky few to eat virtually anything they want and remain razor thin. While fascinating us with stories of genetic peculiarities, Chiu also manages to effortlessly explain much of the cutting-edge research in modern genetics, resulting in a book that is both informative and entertaining. It is a must read for everyone who loves popular science or is curious about the human body.

    In The Cool Impossible, Orton shares his wealth of knowledge in an inspiring step-by-step guide that will open up a new world of achievement for runners of all levels of ability and experience.The truth is: Athleticism is awareness. That simple phrase is at the core of The Cool Impossible. Athleticism requires awareness of form and technique, awareness of our effort level, and, most important, awareness of what we think (and don’t think). And with that awareness comes the possibility of endless potential and improvement, progress and mastery—and, ultimately, achievement that you never before would have thought possible.With a program focused on proper running form, strength development, and cardiovascular training, Orton will help first-step beginners, prime-time competitors, and enduring veterans reach “the cool impossible”—the belief that any achievement, athletic or otherwise, is within our reach. Inside you’ll find:* Foot strength exercises to catapult performance, combat injuries, and transform technique* A total-body strength program aimed at creating an athletic running body* Step-by-step run-form coaching for performance enhancement and lifelong healthy running* A run-training program providing the building blocks for endurance, strength, and speed* No-nonsense nutrition strategies for performance, health, and the ultimate running body* Visualization and mind-training tactics to run and live the Cool Impossible*And much more…Natural running is about so much more than barefoot running. It’s about the joy of running that we were all naturally born with and can reawaken. Like a favorite running companion, The Cool Impossible will be there with you, stride for stride and mile for mile, helping you go farther than you ever could have on your own.Includes a foreword by Christopher McDougall.

    Provocative and engaging, the Best American Science Writing 2009 as edited by Angier covers the full spectrum of scientific inquiry—from biochemistry, physics, and astronomy to genetics, evolutionary theory, and cognition.Introduction / by Natalie Angier --The itch / Atul Gawande --Twitchy / Sallie Tisdale --The first ache / Annie Murphy Paul --A journey inside the brain / Oliver Sacks --The truth about autism / David Wolman --Blocking the transmission of violence / Alex Kotlowitz --Reading the wounds / Jina Moore --A cloud of smoke / Jennifer Kahn --War! What is it good for? Absolutely nothing / John Horgan --Face-offs of the female kind / Marina Cords --Tough lessons from golden rice / Martin Enserink --Back to the future / J. Madeleine Nash --A tall, cool drink of ... sewage? / Elizabeth Royte --Contagious cancer / David Quammen --Looking up / Jennifer Margulis --Birdbrain / Margaret Talbot --Want to remember everything you'll ever learn? Surrender to this algorithm / Gary Wolf --Hello, HAL / John Seabrook --The anonymity experiment / Catherine Price --The sky is falling / Gregg Easterbrook --Big brain theory: have cosmologists lost theirs? / Dennis Overbye --The final frontier / Karen Olsson --Perhaps death is proud; more reason to savor life / Theresa Brown --Evolutionists flock to Darwin-shaped wall stain / The Onion

    The Fast-5 rule is simple -- eat within five consecutive hours. The book is about how to get started, what to expect, and how to deal with the challenges of eating in a way that's not the social norm, but saves time, saves money, and is one of the most easily sustained choices for getting to and maintaining a healthy weight.

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    The year is 2005. A highly infectious, unidentified Ebola-like virus is sweeping through the slums and villages of northern Angola. Within months, more than 200 people have died, medical services have collapsed and aid workers are on the brink of exhaustion. At 23, Peter Apps was just starting out as a foreign correspondent when Reuters sent him into the heart of the outbreak to get the story. In “Before Ebola: Dispatches from a Deadly Outbreak” Apps recalls in vivid, unflinching detail the horrors of life in a hot zone, the compassion of those trying to contain it, and how a terrified young journalist came of age in a time of almost unbearable crisis. Peter Apps is a global defense correspondent for Reuters news, currently dividing his time between London and Washington, D.C. In September 2006, Apps broke his neck in a minibus crash while covering the Sri Lankan civil war, leaving him largely paralyzed from the shoulders down. Cover design by Kristen Radtke.

    It infected nearly one-third of the world’s population and killed ten percent of those it struck. In its wake, schools and businesses closed, hospitals became overwhelmed, and the sick spilled out into makeshift care centers in public spaces. Policemen, public transportation workers, and everyday citizens in face masks were a common—and eerie—sight. Yet, discussion of this global pandemic often takes a backseat to World War I and other contemporary events.

    Meridian exercise is a technique developed and perfected over the course of thousands of years in the Asian healing arts traditions.

    This distinctive text was developed to stand apart from all other A&P texts with unparalleled art, a writing style that has been acclaimed by both users and reviewers and clinical coverage that offers the perfect balance without being too much. Saladin's well-accepted organization of topics is based upon the most logical physiological ties between body systems. This text requires no prior knowledge of college chemistry or cell biology, and is designed for a two-semester A&P college course.

    A leading neurologist offers a new collection of essays about the strange and frightening things that happen when the workings of the human brain go awry.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    Researchers are delving into the mysteries of stem cells and the human genome, discovering what it means to grow old and how to keep those processes from happening. This isn't science fiction; it's real, it's serious, and it's on track to revolutionize our definitions of life and mortality.In Immortality, Inc., veteran science journalist Chip Walter gains exclusive access to the champions of this radical cause, delivering a book that brings together for the first time the visions of molecular biologist and Apple chairman Arthur Levinson, genomics entrepreneur Craig Venter, futurist Ray Kurzweil, rejuvenation trailblazer Aubrey de Grey, and stem cell expert Robert Hariri. Along the way, Walter weaves in fascinating conversations about life, death, aging, and the future of the human race.

    This book will show you that you do not have to be born with a silver spoon, come from royalty, become a celebrity or date the richest guy in the world to become elegant. The book contains practical tips and tricks on how to achieve elegance without the need for stylists, a walk-in closet and all the fancy things we think we need to be elegant. It will help you understand what works for you, what will feel good for you and what is suitable for the different roles that you play in life.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.