Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    This popular Blueprints book has been refined and updated while keeping the concise, organized style and clinical high-yield content of previous editions. Features include USMLE-style questions and answers with full explanations; Key Points in every section; and a color-enhanced design that increases the usefulness of figures and tables.This edition's completely revised art program includes many additional illustrations. Each chapter in this edition ends with evidence-based references (journals) for students to do additional reading/research.

    Each case includes an extended discussion, definition of terms, clinical pearls, and USMLE format review questions. This interactive learning system is proven to improve shelf-exam scores and helps students to learn in the context of real patients insted of simply memorizing.

    No matter what you’ve heard, there are always steps you can take to help your dog fight (and even beat) cancer. This scientifically researched guide is your complete reference for practical, evidence-based strategies that can optimize the life quality and longevity for your dog. No matter what diagnosis or stage of cancer your dog has, this book is packed with precious advice that can help now. Discover the Full Spectrum approach to dog cancer care: * Everything you need to know about conventional western veterinary treatments (surgery, chemotherapy and radiation) including how to reduce their side effects. * The most effective non-conventional options, including botanical nutraceuticals, supplements, nutrition, and mind-body medicine. * How to analyze the options and develop a specific plan for your own dog based on your dog’s type of cancer, your dog’s age, your financial and time budget, your personality, and many other personal factors. Imagine looking back at this time in your life, five years from now, and having not a single regret. You can help your dog fight cancer and you can honor your dog’s life by living each moment to the fullest, starting now. This book can help you as it has helped thousands of other dog lovers. THE AUTHORS Dr. Demian Dressler, DVM practices in Hawaii and is internationally recognized as "the dog cancer vet" Dr. Susan Ettinger, DVM is a veterinary oncologist and a diplomate of the American College of Internal Medicine who practices in New York. PRAISE FROM VETERINARIANS, AUTHORS & BOOK REVIEWERS"The future is upon us and this ground-breaking book is a vital cornerstone. In dealing with cancer, our worst illness, this Survival Guide is educational, logical, expansive, embracing, honest and so needed." -Dr. Marty Goldstein, DVMHolistic veterinarian and Host, Ask Martha Stewart’s Vet on Sirius Radio "The message of this book jumps off the written page and into the heart of every reader, and will become the at home bible for cancer care of dogs. The authors have given you a sensible and systematic approach that practicing veterinarians will cherish. I found the book inspiring and, clearly, it will become part of my daily approach to cancer therapy for my own patients." -Dr. Robert B. Cohen, VMD Bay Street Animal Hospital, New York "I wish that I had had The Dog Cancer Survival Guide when my dearly beloved Flat-coated Retriever, Odin, contracted cancer. It would have provided me alternative courses of action, as well as some well needed "reality checks" which were not available from conversations with my veterinarian. It should be on every dog owner’s book shelf--just in case..." -Dr. Stanley Coren, PhD, FRSC author of many books, including Born to Bark "A comprehensive guide that distills both alternative and allopathic cancer treatments in dogs...With the overwhelming amount of conflicting information about cancer prevention and treatment, this book provides a pet owner with an easy to follow approach to one of the most serious diseases in animals." -Dr. Barbara Royal, DVM The Royal Treatment Veterinary Center, Oprah Winfrey’s Chicago veterinarian "Picking up The Dog Cancer Survival Guide is anything but a downer: it's an 'empowerer.' It will make you feel like the best medical advocate for your dog. It covers canine cancer topics to an unprecedented depth and breadth from emotional coping strategies to prevention-in plain English.

    Set out logically and systematically, this best-selling textbook has comprehensive coverage of essential skills necessary for history taking and examining the patient. Highly regarded by students world-wide, this text continues to grow in strength. Clinical Examination, 5th edition has been revised and updated to include: more evidence-based medicine; new full-color artwork; and a fresh new look allowing greater accessibility for readers. The new edition covers clinical examination and concepts in a systems approach in a clear, consistent and user-friendly approach. Readers using this edition of Clinical Examination will have access to www.studentconsult.com. Here you will receive full online access to the text and numerous interactive extras such as video clips demonstrating some of the more difficult examinations & MCQ's. Written by two internationally renowned authors, Clinical Examination, 5th edition will continue to provide students with a superb reference for performing clinical methods.

    In bulleted lists, tables, and algorithms, Pocket Medicine provides key clinical information about common problems in cardiology, pulmonology, gastroenterology, nephrology, hematology-oncology, infectious diseases, endocrinology, rheumatology, and neurology.The six-ring binder resembles the familiar "pocket brain" notebook that most students and interns carry and allows users to add notes. This Third Edition is fully updated, has tabs to help readers locate organ systems, and has more cross-referencing in the index. It also has pockets in the front and the back of the book to accommodate the reader's own notes.

    The 7th edition incorporates the latest advances in molecular diagnostics, the Human Genome Project, and much more. More than 240 dynamic illustrations and high-quality photos help you grasp complex concepts more easily. In addition to the book, you will also receive STUDENT CONSULT, enabling you to access the complete contents of the book online, anywhere you go

    . . Again!Did the mega-bestselling Why Do Men Have Nipples? exhaust your curiosity about stuff odd, icky, kinky, noxious, libidinous, or just plain embarrassing? No, you say? Well, good, because the doctor and his able-bodied buddy are in! Again! Mark Leyner and Billy Goldberg, M.D., now take on the differences between the sexes—those burning questions like Why doesn’t my husband ever listen? or Why does my wife ALWAYS have to pee? And of course, Why do men fall asleep after sex?, plus plenty of others to keep you fully informed.Full of smart and funny answers to an onslaught of new questions, all in a do-ask-we’ll-tell spirit that entertain and teaches you something at the same time, Why Do Men Fall Asleep After Sex? offers the real lowdown on everything everyone wants to know about all things anatomical, medical, sexual, nutritional, animal, and mineral, but would only ask a physician after a few too many, like:• Why do you have a “bionic” sense of smell when you’re pregnant?• Does peeing in the shower cure athlete’s foot?• Is a dog’s mouth clean?• Can you breastfeed with fake boobs?• Does thumb sucking cause buckteeth?• Do your eyebrows grow back if shaved? Bigger, funnier, and better than ever, Why Do Men Fall Asleep After Sex? proves that in the battle of the sexes, as in most things, a little Q&A is a safe, effective, minimally invasive remedy.Also available as an eBook

    Gifted Bible preacher and inspiring teacher Jon Courson effortlessly combines both in this easy-to-read, verse-based devotional commentary on the New Testament.Pastor Jon's years of immersion in God's Word, as he regularly preached from the Bible, produced faithful, valuable teaching that is both a scholarly work and an encouragement for living the Christian life. His application commentaries combine the following elements in a unique blend of pertinent information and needed inspiration:Deep love for God's wordColorful cultural insightsInsightful historical informationApplicable topical studiesVivid illustrations and storiesHumorous, practical, and inspiring life lessonsJon Courson's devotional commentaries offer thorough and comprehensive teaching along with practical, in-depth topical studies in a very readable and comfortable expositional style.

    Her parents are nearly bankrupt and being forced to sell their family home, a beautiful Tudor house that has been in the family for generations, thanks to Amber's ex-fiance persuading them to invest in his dodgy shares. Armed with a self-help book and a ten-point plan, she sets off to hook herself a rich husband. On a millionaire's yacht, she meets the drop-dead gorgeous Jed Curtess. The attraction between them is sizzling. It's a shame that he is only a hired hand. Can Amber ignore her heart and follow her plan?

    Popular author and photography instructor Julie Adair King shows you how to use all the settings, manage playback options, take control with manual modes, work with video, and edit and share your images. It's like a personal course in beginning dSLR photography.New dSLR users will quickly gain skills and confidence with the step-by-step, colorfully illustrated instructions in this beginner's guide to the Nikon D3200 camera Explains how to use all the new features of the Nikon D3200, including a 24-megapixel sensor, 11 autofocus points, 4 frame-per-second shooting, full HD video capabilities, and a WiFi feature that lets you control the camera remotely or preview images on your smartphone Covers auto and manual modes, playback options, working with exposure and focus, shooting video, editing and sharing photos, troubleshooting, and photography tips Popular author has written more than 15 For Dummies books on Nikon and Canon cameras Nikon D3200 For Dummies is the easy, full-color, and fun way to start making the most of your new camera right away.

    Each book now includes sixteen-addtional pages with brand-new content! Minecraft--the indie sandbox video game that took the world by storm--has been hailed as one of the greatest phenomena amongst gamers and educators for both its simplicity and its brilliance. Allowing players to build, explore, create, collaborate, and even survive, Minecraft has created a brave new world of gameplay. Each handbook contains helpful tips and information from the creators themselves, all of which will prove vital to your survival and creativity as you learn to mine, craft, and build in a world that you control.

    Their dedication and hard work have yielded an authoritative volume that defines and classifies mental disorders in order to improve diagnoses, treatment, and research.The criteria are concise and explicit, intended to facilitate an objective assessment of symptom presentations in a variety of clinical settings -- inpatient, outpatient, partial hospital, consultation-liaison, clinical, private practice, and primary care. New features and enhancements make DSM-5 easier to use across all settings:- The chapter organization reflects a lifespan approach, with disorders typically diagnosed in childhood (such as neurodevelopmental disorders) at the beginning of the manual, and those more typical of older adults (such as neurocognitive disorders) placed at the end. Also included are age-related factors specific to diagnosis. - The latest findings in neuroimaging and genetics have been integrated into each disorder along with gender and cultural considerations.- The revised organizational structure recognizes symptoms that span multiple diagnostic categories, providing new clinical insight in diagnosis. - Specific criteria have been streamlined, consolidated, or clarified to be consistent with clinical practice (including the consolidation of autism disorder, Asperger's syndrome, and pervasive developmental disorder into autism spectrum disorder; the streamlined classification of bipolar and depressive disorders; the restructuring of substance use disorders for consistency and clarity; and the enhanced specificity for major and mild neurocognitive disorders).- Dimensional assessments for research and validation of clinical results have been provided.- Both ICD-9-CM and ICD-10-CM codes are included for each disorder, and the organizational structure is consistent with the new ICD-11 in development.The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, is the most comprehensive, current, and critical resource for clinical practice available to today's mental health clinicians and researchers of all orientations. The information contained in the manual is also valuable to other physicians and health professionals, including psychologists, counselors, nurses, and occupational and rehabilitation therapists, as well as social workers and forensic and legal specialists.

    The village was agog, the congregation surprised and in some cases not at all pleased.Venus - a name wished on her by her otherwise conventional parents, and which she felt wholly inappropriate for a woman priest - had to endure curiosity, misunderstandings and even downright hostility. But she also found warmth, friendship and kindness - sometimes from the most unexpected quarters.Still mourning the death of her husband, and having to cope with the problems of single parenthood, Venus began to think that she would never manage the task she had set herself. Perhaps the doubters were right - she was not suited to be a vicar, to care for the souls of the parish. But the handsome local doctor thought otherwise, and so did many others who came to regard her not only as their priest but also their friend.

    In this MTHFR booklet, learn why Dr Lynch has dedicated himself to expanding awareness of the MTHFR gene defect - and more importantly, how you can be proactive in optimizing your health.