The popularity of murder mystery books, TV series, and even board games shows that there is an appetite for death, and the more unusual or macabre the method, the better. With gunshots or stabbings the cause of death is obvious, but poisons are inherently more mysterious. How are some compounds so deadly in such tiny amounts?Agatha Christie used poison to kill her characters more often than any other crime fiction writer. The poison was a central part of the novel, and her choice of deadly substances was far from random; the chemical and physiological characteristics of each poison provide vital clues to the discovery of the murderer. Christie demonstrated her extensive chemical knowledge (much of it gleaned by working in a pharmacy during both world wars) in many of her novels, but this is rarely appreciated by the reader.Written by former research chemist Kathryn Harkup, each chapter takes a different novel and investigates the poison used by the murderer. Fact- and fun-packed, A is for Arsenic looks at why certain chemicals kill, how they interact with the body, and the feasibility of obtaining, administering, and detecting these poisons, both when Christie was writing and today.

    They remove the books that patrons no longer check out. And they put back the books they treasure. Annie Spence, who has a decade of experience as a Midwestern librarian, does this not only at her Michigan library but also at home, for her neighbors, at cocktail parties—everywhere. In Dear Fahrenheit 451, she addresses those books directly. We read her love letters to The Goldfinch and Matilda, as well as her snarky break-ups with Fifty Shades of Grey and Dear John. Her notes to The Virgin Suicides and The Time Traveler’s Wife feel like classics, sure to strike a powerful chord with readers. Through the lens of the books in her life, Annie comments on everything from women’s psychology to gay culture to health to poverty to childhood aspirations. Hilarious, compassionate, and wise, Dear Fahrenheit 451 is the consummate book-lover's birthday present, stocking stuffer, holiday gift, and all-purpose humor book.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    It gives your body its shape and the ability to move. It grows and changes with you, an undeniable document of who you are and how you lived. Arguably, no other part of the human anatomy has such rich scientific and cultural significance, both brimming with life and a potent symbol of death.In this delightful natural and cultural history of bone, Brian Switek explains where our skeletons came from, what they do inside us, and what others can learn about us when these artifacts of mineral and protein are all we've left behind.Bone is as embedded in our culture as it is in our bodies. Our species has made instruments and jewelry from bone, treated the dead like collectors' items, put our faith in skull bumps as guides to human behavior, and arranged skeletons into macabre tributes to the afterlife. Switek makes a compelling case for getting better acquainted with our skeletons, in all their surprising roles. Bridging the worlds of paleontology, anthropology, medicine, and forensics, Skeleton Keys illuminates the complex life of bones inside our bodies and out.

    For the past two millennia, the ability to produce it in ever more efficient ways has supported the proliferation of literacy, media, religion, education, commerce, and art; it has formed the foundation of civilizations, promoting revolutions and restoring stability. One has only to look at history’s greatest press run, which produced 6.5 billion copies of Máo zhuxí yulu, Quotations from Chairman Mao Tse-tung (Zedong)—which doesn’t include editions in 37 foreign languages and in braille—to appreciate the range and influence of a single publication, in paper. Or take the fact that one of history’s most revered artists, Leonardo da Vinci, left behind only 15 paintings but 4,000 works on paper. And though the colonies were at the time calling for a boycott of all British goods, the one exception they made speaks to the essentiality of the material; they penned the Declaration of Independence on British paper.Now, amid discussion of “going paperless”—and as speculation about the effects of a digitally dependent society grows rampant—we’ve come to a world-historic juncture. Thousands of years ago, Socrates and Plato warned that written language would be the end of “true knowledge,” replacing the need to exercise memory and think through complex questions. Similar arguments were made about the switch from handwritten to printed books, and today about the role of computer technology. By tracing paper’s evolution from antiquity to the present, with an emphasis on the contributions made in Asia and the Middle East, Mark Kurlansky challenges common assumptions about technology’s influence, affirming that paper is here to stay. Paper will be the commodity history that guides us forward in the twenty-first century and illuminates our times.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    There was nothing surprising about men turning up dead in the Second City. Life was cheaper than a quart of illicit gin in the gangland capital of the world. But two murders that spring were special - worthy of celebration. So believed Maurine Watkins, a wanna-be playwright and a "girl reporter" for the Chicago Tribune, the city's "hanging paper." Newspaperwomen were supposed to write about clubs, cooking and clothes, but the intrepid Miss Watkins, a minister's daughter from a small town, zeroed in on murderers instead. Looking for subjects to turn into a play, she would make "Stylish Belva" Gaertner and "Beautiful Beulah" Annan - both of whom had brazenly shot down their lovers - the talk of the town. Love-struck men sent flowers to the jail and newly emancipated women sent impassioned letters to the newspapers. Soon more than a dozen women preened and strutted on "Murderesses' Row" as they awaited trial, desperate for the same attention that was being lavished on Maurine Watkins's favorites. In the tradition of Erik Larson's The Devil in the White City and Karen Abbott's Sin in the Second City, Douglas Perry vividly captures Jazz Age Chicago and the sensationalized circus atmosphere that gave rise to the concept of the celebrity criminal. Fueled by rich period detail and enlivened by a cast of characters who seemed destined for the stage, The Girls of Murder City is crackling social history that simultaneously presents the freewheeling spirit of the age and its sober repercussions.

    From the research biologist who stung himself with every conceivable insect to the world's most murderous mammals, this book explores oft-ignored but alluring facets of biology, anatomy, space exploration, nature, and more. Featuring interviews with leading researchers in the field and a large dose of wit, the author reveals the most intriguing real-world applications of science in all their glory.

    They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

    Washington became the kind of man who named his dog Sweetlips and hated to leave home. He took up arms against the British only when there was no other way, though he lost more battles than he won. Coe focuses on his activities off the battlefield—like espionage and propaganda.After an unlikely victory in the Revolutionary War, Washington once again shocked the world by giving up power, only to learn his compatriots wouldn't allow it. The founders pressured him into the presidency—twice. He established enduring norms but left office heartbroken over the partisan nightmare his backstabbing cabinet had created.Back on his plantation, the man who fought for liberty finally confronted his greatest hypocrisy—what to do with the hundreds of men, women, and children he owned—before succumbing to a brutal death.Alexis Coe combines rigorous research and unsentimental storytelling, finally separating the man from the legend.

    Her book is a delightful and perfect reflection of her. Its tenderness sneaks up on you and really packs a punch. What a magnificent read!"--Julia Louis DreyfusJenny Lawson meets Nora Ephron in this joyful memoir-in-vignettes on living--and thriving--with anxiety from a multiple Emmy Award-winning comedy writer whose credits include Succession and Veep.When Georgia Pritchett found herself lost for words--a bit of a predicament for a comedy writer--she turned to a therapist, who suggested she try writing down some of the things that worried her. But instead of a grocery list of concerns, Georgia wrote this book.A natural born worrywart, Georgia's life has been defined by her quirky anxiety. During childhood, she was agitated about the monsters under her bed (Were they comfy enough?). Going into labor, she fretted about making a fuss ("Sorry to interrupt, but the baby is coming out of my body," I said politely). Winning a prestigious award, she agonized over receiving free gifts after the ceremony (It was an excruciating experience. Mortifying).Soul-baring yet lighthearted, poignant yet written with a healthy dose of self-deprecation, My Mess Is a Bit of a Life is a tour through the carnival funhouse of Georgia's life, from her anxiety-ridden early childhood where disaster loomed around every corner (When I was little I used to think that sheep were clouds that had fallen to earth. On cloudy days I used to worry that I would be squashed by a sheep), through the challenges of breaking into an industry dominated by male writers, to the exquisite terror (and incomparable joy) of raising children.Delightfully offbeat, painfully honest, full of surprising wonders, and delivering plenty of hilarious, laugh-out-loud moments, My Mess Is a Bit of a Life reveals a talented, vulnerable, and strong woman in all her wisecracking weirdness, and makes us love it--and her--too.

    In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.

    Regularly, repeatedly, and with impunity, queens like Hatshepsut, Nefertiti, and Cleopatra controlled the totalitarian state as power-brokers and rulers. But throughout human history, women in positions of power were more often used as political pawns in a male-dominated society. What was so special about ancient Egypt that provided women this kind of access to the highest political office? What was it about these women that allowed them to transcend patriarchal obstacles? What did Egypt gain from its liberal reliance on female leadership, and could today's world learn from its example?Celebrated Egyptologist Kara Cooney delivers a fascinating tale of female power, exploring the reasons why it has seldom been allowed through the ages, and why we should care.