Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    The adjective 'medieval' has become a synonym for brutality and uncivilized behavior. Yet without the work of medieval scholars there could have been no Galileo, no Newton and no Scientific Revolution. In God's Philosophers, James Hannam debunks many of the myths about the Middle Ages, showing that medieval people did not think the earth is flat, nor did Columbus 'prove' that it is a sphere; the Inquisition burnt nobody for their science nor was Copernicus afraid of persecution; no Pope tried to ban human dissection or the number zero. God's Philosophers is a celebration of the forgotten scientific achievements of the Middle Ages - advances which were often made thanks to, rather than in spite of, the influence of Christianity and Islam. Decisive progress was also made in technology: spectacles and the mechanical clock, for instance, were both invented in thirteenth-century Europe. Charting an epic journey through six centuries of history, God's Philosophers brings back to light the discoveries of neglected geniuses like John Buridan, Nicole Oresme and Thomas Bradwardine, as well as putting into context the contributions of more familiar figures like Roger Bacon, William of Ockham and Saint Thomas Aquinas.

    They were hunter-gatherers, consummate foraging experts, but taking the world as they found it. Then a revolution occurred – our ancestors’ interaction with other species changed. They began to tame them. The human population boomed; civilization began.In her new book, Tamed, Alice Roberts uncovers the amazing deep history of ten familiar species with incredible wild pasts: dogs, apples and wheat; cattle; potatoes and chickens; rice, maize, and horses – and, finally, humans. Alice Roberts not only reveals how becoming part of our world changed these animals and plants, but shows how they became our allies, essential to the survival and success of our own species – and to our future.Enlightening, wide-ranging and endlessly fascinating, Tamed is an epic story, encompassing hundreds of thousands of years of history and archaeology alongside cutting-edge genetics and anthropology. Yet it is also a deeply personal journey that will change how we see ourselves and the species on which we have left our mark.

    It is the story of diplomats, traders, scientists, and aristocratic amateur naturalists charged by Sir Stamford Raffles with collecting amazing creatures from all four corners of the globe.It is the story of the first zoo in history, a weird and wonderful oasis in the heart of the filthy, swirling city of Dickensian London, and of the incredible characters, both human and animal, that populated it—from Charles Darwin and Queen Victoria to Obaysch the celebrity hippo, the first that anyone in Britain had ever seen. This is a story of Victorian grandeur, of science and empire, and of adventurers and charlatans.And it is the story of a dizzying age of Empire and industrialization, a time of change unmatched before or since.This is the extraordinary story of London Zoo.

    When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

    Operating in Chicago’s notorious Levee district at the dawn of the last century, the Club’s proprietors, two aristocratic sisters named Minna and Ada Everleigh, welcomed moguls and actors, senators and athletes, foreign dignitaries and literary icons, into their stately double mansion, where thirty stunning Everleigh “butterflies” awaited their arrival. Courtesans named Doll, Suzy Poon Tang, and Brick Top devoured raw meat to the delight of Prince Henry of Prussia and recited poetry for Theodore Dreiser. Whereas lesser madams pocketed most of a harlot’s earnings and kept a “whipper” on staff to mete out discipline, the Everleighs made sure their girls dined on gourmet food, were examined by an honest physician, and even tutored in the literature of Balzac.Not everyone appreciated the sisters’ attempts to elevate the industry. Rival Levee madams hatched numerous schemes to ruin the Everleighs, including an attempt to frame them for the death of department store heir Marshall Field, Jr. But the sisters’ most daunting foes were the Progressive Era reformers, who sent the entire country into a frenzy with lurid tales of “white slavery-the allegedly rampant practice of kidnapping young girls and forcing them into brothels. This furor shaped America’s sexual culture and had repercussions all the way to the White House, including the formation of the Federal Bureau of Investigation.With a cast of characters that includes Jack Johnson, John Barrymore, John D. Rockefeller, Jr., William Howard Taft, “Hinky Dink” Kenna, and Al Capone, Sin in the Second City is Karen Abbott’s colorful, nuanced portrait of the iconic Everleigh sisters, their world-famous Club, and the perennial clash between our nation’s hedonistic impulses and Puritanical roots. Culminating in a dramatic last stand between brothel keepers and crusading reformers, Sin in the Second City offers a vivid snapshot of America’s journey from Victorian-era propriety to twentieth-century modernity.

    Archaeologist and medieval historian Alexander Langlands reaches as far back as the Neolithic period to recover our lost sense of craft, combining deep history with detailed scientific analyses and his own experiences making traditional crafts. Craft brims with vivid storytelling, rich descriptions of natural landscape, and delightful surprises that will convince us to introduce more craft into our lives.

    These marvellous and mysterious phantoms - non-existent islands, invented mountain ranges, mythical civilisations and other fictitious geography - were all at various times presented as facts on maps and atlases. This book is a collection of striking antique maps that display the most erroneous cartography, with each illustration accompanied by the story behind it.      Exploration, map-making and mythology are all brought together to create a colourful tapestry of monsters, heroes and volcanoes; swindlers, mirages and murderers. Sometimes the stories are almost impossible to believe, and remarkably, some of the errors were still on display in maps published in the 21st century. Throughout much of the 19th century more than 40 different mapmakers included the Mountains of Kong, a huge range of peaks stretching across the entire continent of Africa, in their maps - but it was only in 1889 when Louis Gustave Binger revealed the whole thing to be a fake. For centuries, explorers who headed to Patagonia returned with tales of the giants they had met who lived there, some nine feet tall. Then there was Gregor MacGregor, a Scottish explorer who returned to London to sell shares in a land he had discovered in South America. He had been appointed the Cazique of Poyais, and bestowed with many honours by the local king of this unspoiled paradise. Now he was offering others the chance to join him and make their fortune there, too - once they had paid him a bargain fee for their passage...       The Phantom Atlas is a beautifully produced volume, packed with stunning maps and drawings of places and people that never existed. The remarkable stories behind them all are brilliantly told by Edward Brooke-Hitching in a book that will appeal to cartophiles everywhere.

    Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In prose that is at once frank, entertaining, and deeply informed, The New Yorker writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

    They have done so since before recorded history. Flowers are used to celebrate all-important occasions, to express love, and are also the basis of global industries. Americans buy ten million flowers a day and perfumes are a worldwide industry worth $30 billion dollars annually. Yet, we know little about flowers, their origins, bizarre sex lives, or how humans relate and depend upon them.Stephen Buchmann takes us along on an exploratory journey of the roles flowers play in the production of our foods, spices, medicines, perfumes, while simultaneously bringing joy and health. Flowering plants continue to serve as inspiration in our myths and legends, in the fine and decorative arts, and in literary works of prose and poetry. Flowers seduce us—and animals, too—through their myriad shapes, colors, textures, and scents. And because of our extraordinary appetite for more unusual and beautiful “super flowers,” plant breeders have created such unnatural blooms as blue roses and black petunias to cater to the human world of haute couture fashion. In so doing, the nectar and pollen vital to the bees, butterflies, and bats of the world, are being reduced. Buchmann explains the unfortunate consequences, and explores how to counter them by growing the right flowers. Here, he integrates fascinating stories about the many colorful personalities who populate the world of flowers, and the flowers and pollinators themselves, with a research-based narrative that illuminates just why there is, indeed, a Reason for Flowers.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    They found a tiny office on London’s Bond Street and set about the delicate business of matchmaking. Drawing on the bureau’s extensive archives, Penrose Halson—who many years later found herself the proprietor of the bureau—tells their story, and those of their clients.From shop girls to debutantes; widowers to war veterans, clients came in search of security, social acceptance, or simply love. And thanks to the meticulous organization and astute intuition of the Bureau’s matchmakers, most found what they were looking for.Penrose Halson draws from newspaper and magazine articles, advertisements, and interviews with the proprietors themselves to bring the romance and heartbreak of matchmaking during wartime to vivid, often hilarious, life in this unforgettable story of a most unusual business.“A book full of charm and hilarity.”—Country Life

    It accommodates four of our five senses, encases the brain, and boasts the most expressive set of muscles in the body. It is our most distinctive attribute and connects our inner selves to the outer world. Yet there is a dark side to the head’s preeminence, one that has, in the course of human history, manifested itself in everything from decapitation to headhunting. So explains anthropologist Frances Larson in this fascinating history of decapitated human heads. From the Western collectors whose demand for shrunken heads spurred massacres to Second World War soldiers who sent the remains of the Japanese home to their girlfriends, from Madame Tussaud modeling the guillotined head of Robespierre to Damien Hirst photographing decapitated heads in city morgues,from grave-robbing phrenologists to skull-obsessed scientists, Larson explores our macabre fixation with severed heads.

    Of these, gravity may the most obvious, but it is also the most mysterious. Newton managed to predict the force of gravity but couldn't explain how it worked at a distance. Einstein picked up on the simple premise that gravity and acceleration are interchangeable to devise his mind-bending general relativity, showing how matter warps space and time. Not only did this explain how gravity worked – and how apparently simple gravitation has four separate components – but it predicted everything from black holes to gravity's effect on time. Whether it's the reality of anti-gravity or the unexpected discovery that a ball and a laser beam drop at the same rate, gravity is the force that fascinates.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.