The culprit--so necessary and yet the source of such upheaval--is the X chromosome, and this is its story. An enlightening and entertaining tour of the cultural and natural history of this intriguing member of the genome, "The X in Sex" traces the journey toward our current understanding of the nature of X. From its chance discovery in the nineteenth century to the promise and implications of ongoing research, David Bainbridge shows how the X evolved and where it and its counterpart Y are going, how it helps assign developing human babies their sex--and maybe even their sexuality--and how it affects our lives in infinitely complex and subtle ways. X offers cures for disease, challenges our cultural, ethical, and scientific assumptions about maleness and femaleness, and has even reshaped our views of human evolution and human nature.

    The implications of their discoveries form tomorrow's headlines, yet Angier writes about the scientists themselves and not merely theri successes. 4-page photo insert.

    Sometimes, they're wrong. At Chelsea General, surgeons answer for bad outcomes at the Morbidity and Mortality conference, known as M & M. This extraordinary peek behind the curtain into what is considered the most secretive meeting in all of medicine is the back drop for the entire book.Monday Mornings, by Dr. Sanjay Gupta, follows the lives of five surgeons at Chelsea General as they push the limits of their abilities and confront their personal and professional failings, often in front of their peers at M & M. It is on Monday mornings that reflection and introspection occurs, usually in private. It is Monday Mornings that provides a unique look at the real method in which surgeons learn - through their mistakes. It is Monday Mornings when, if you're lucky, you have a chance at redemption.

    Nina Shapiro’s engaging and informative look at the real science behind our most common beliefs and assumptions in the health sphere. There is a lot of misinformation thrown around these days, especially online. Headlines tell us to do this, not that—all in the name of living longer, better, thinner, younger. Dr. Shapiro wants to distinguish between the falsehoods and the evidence-backed truth. In her work at Harvard and UCLA, with more than twenty years of experience in both clinical and academic medicine, she helps patients make important health decisions every day. She’s bringing those lessons to life here with a blend of personal storytelling and science to discuss her dramatic new definition of “a healthy life.”Hype covers everything from exercise to supplements, alternative medicine to vaccines, and medical testing to media coverage. Shapiro tackles popular misconceptions such as toxic sugar and the importance of drinking eight glasses of water a day. She provides simple solutions anyone can implement, such as drinking 2% milk instead of fat free and using SPF 30 sunscreen instead of SPF 100. This book is as much for single individuals in the prime of their lives as it is for parents with young children and the elderly.Never has there been a greater need for this reassuring, and scientifically backed reality check.

    They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    microbe.” —The Wall Street Journal   Did the Black Death destroy medieval Europe? Did cholera pave the way for modern Manhattan? Did yellow fever help end the slave trade? Remarkably, the answer to all of these questions is yes. Time and again, diseases have impacted the course of human history in surprisingly powerful ways. From influenza to smallpox, from tuberculosis to yellow fever, Bryn Barnard describes the symptoms and paths of the world’s worst diseases—and how the epidemics they spawned have changed history forever.   Filled with fascinating, often gory details about disease and history, Outbreak! is a wonderful combination of science and history.

    Rana Awdish never imagined that an emergency trip to the hospital would result in hemorrhaging nearly all of her blood volume and losing her unborn first child. But after her first visit, Dr. Awdish spent months fighting for her life, enduring consecutive major surgeries and experiencing multiple overlapping organ failures. At each step of the recovery process, Awdish was faced with something even more unexpected: repeated cavalier behavior from her fellow physicians—indifference following human loss, disregard for anguish and suffering, and an exacting emotional distance.Hauntingly perceptive and beautifully written, In Shock allows the reader to transform alongside Awidsh and watch what she discovers in our carefully-cultivated, yet often misguided, standard of care. Awdish comes to understand the fatal flaws in her profession and in her own past actions as a physician while achieving, through unflinching presence, a crystalline vision of a new and better possibility for us all.As Dr. Awdish finds herself up against the same self-protective partitions she was trained to construct as a medical student and physician, she artfully illuminates the dysfunction of disconnection. Shatteringly personal, and yet wholly universal, she offers a brave road map for anyone navigating illness while presenting physicians with a new paradigm and rationale for embracing the emotional bond between doctor and patient.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Too bad. Because medicine isn't an industry, it's practically witchcraft. Despite the growth of big pharma, HMOs, and hospital chains, medicine remains the isolated work of individual doctors—and the system is going broke fast.So why is Andy Kessler—the man who told you outrageous stories of Wall Street analysts gone bad in Wall Street Meat and tales from inside a hedge fund in Running Money—poking around medicine for the next big wave of technology?It's because he smells change coming. Heart attacks, strokes, and cancer are a huge chunk of medical spending, yet there's surprisingly little effort to detect disease before it's life threatening. How lame is that—especially since the technology exists today to create computer-generated maps of your heart and colon?Because it's too expensive—for now. But Silicon Valley has turned computing, telecom, finance, music, and media upside down by taking expensive new technologies and making them ridiculously cheap. So why not the $1.8 trillion health care business, where the easiest way to save money is to stop folks from getting sick in the first place?Join Kessler's bizarre search for the next big breakthrough as he tries to keep from passing out while following cardiologists around, cracks jokes while reading mammograms, and watches twitching mice get injected with radioactive probes. Looking for a breakthrough, Kessler even selflessly pokes, scans, and prods himself.CT scans of your heart will identify problems before you have a heart attack or stroke; a nanochip will search your blood for cancer cells--five years before they grow uncontrollably and kill you; and baby boomers can breathe a little easier because it's all starting to happen now.Your doctor can't be certain what's going on inside your body, but technology will. Embedding the knowledge of doctors in silicon will bring a breakout technology to health care, and we will soon see an end of medicine as we know it.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    But in the modern world, the breast is changing. Breasts are getting bigger, arriving earlier, and attracting newfangled chemicals. Increasingly, the odds are stacked against us in the struggle with breast cancer, even among men. What makes breasts so mercurial—and so vulnerable?In this informative and highly entertaining account, intrepid science reporter Florence Williams sets out to uncover the latest scientific findings from the fields of anthropology, biology, and medicine. Her investigation follows the life cycle of the breast from puberty to pregnancy to menopause, taking her from a plastic surgeon’s office where she learns about the importance of cup size in Texas to the laboratory where she discovers the presence of environmental toxins in her own breast milk. The result is a fascinating exploration of where breasts came from, where they have ended up, and what we can do to save them.

    Diligently researching how to restore his quality of life, she discovered Vet-Stem, a service that provides cutting-edge regeneration therapy for pets, using stem cells harvested from animals' own tissue. Just hours after receiving IV and intra-joint injections, Sam began aging backward--which left Julia wondering why this simple, effective treatment was not available for humans.            Julia suffered from chronic inflammatory bowel disease, and after witnessing Sam's astonishing recovery, she set out on a curious quest: to be treated like a dog by a doctor as competent as her vet! After a four-year wait, Julia became the first American to be successfully cured of a perirectal fistula with stem cells derived from her own fat. With this amazing true story of how a pack of shelter dogs she rescued from death row came to save her life, Julia hopes to inspire and inform readers about exciting healthcare options available to them and their cherished animal companions.

    Close worked desperately to contain the outbreak. Haunted by this wrenching crisis, Dr. Close felt compelled to honor the memory of the courageous people he knew and lost. This is their story: a terrifying, completely authentic novel that begins with an invisible killer.  It strikes without warning—a lethal disease with no name . . . and no cure.   At a Catholic mission in Yambuku, a remote village sixty miles south of the Ebola River, local teacher Mabalo Lokela visits the clinic with a raging fever. Sister Lucie, a Flemish nun and nurse, gives him a shot of an antimalarial drug, wipes off the syringe, and awaits her next patient. Within days, Mabalo is dead. Soon, others are falling ill. Less than three weeks later, the virus claims Sister Lucie’s life as well. Panic erupts, but as the villagers attempt to flee, all roads leading out of Yambuku are closed off, the dying forced back. And as the single radio connecting the mission to the outside world brings only bad news, the valiant nuns and medical personnel left behind have no choice but to pray, and wonder: Will they survive long enough for help to arrive?

    THE NEW YORK TIMES BESTSELLERUnlock the secret to extraordinary health by reducing high uric acid levels—the hidden risk you didn't know you had—by the author of Grain Brain and Brain Wash.What do obesity, insulin resistance, diabetes, fatty liver disease, hypertension, cardiovascular disease, stroke, neurological disorders, and premature death have in common? All can be stoked by high uric acid levels. Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection. This is especially alarming because a large number of Americans don’t know they are suffering from increased levels, putting them at risk for developing or exacerbating potentially life-threatening illnesses. Offering an engaging blend of science and practical advice, Drop Acid exposes the deadly truth about uric acid and teaches invaluable strategies to manage its levels, including how to:Reduce fructose and foods high in “purines” through simple dietary edits Lower uric acid levels through natural hacks like consuming tart cherries, vitamin C, quercetin, and coffeeIdentify common pharmaceuticals that threaten to increase uric acidImplement lifestyle interventions, like restorative sleep and exerciseEasily test your uric acid levels at home—a test routinely performed in your doctor’s office during regular check-ups but typically ignoredFeaturing the groundbreaking “LUV” (Lower Uric Values) diet, 35 delicious recipes, self-assessment quizzes, and a 21-day program for dropping levels, Drop Acid empowers readers with the information they need to address this hidden danger and live longer, leaner, and healthier lives.