As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    The Muppets made Jim Henson a household name, but they were only part of his remarkable story.This extraordinary biography--written with the generous cooperation of the Henson family--covers the full arc of Henson's all-too-brief life: from his childhood in Leland, Mississippi, through the years of burgeoning fame in Washington D.C., New York, and London, to the decade of international celebrity that preceded his untimely death at age fifty-three. Drawing on hundreds of hours of new interviews with Jim Henson's family, friends, and closest collaborators, as well as unprecedented access to private family and company archives--including never-before-seen interviews, business documents, and Henson's private letters--Brian Jay Jones explores the creation of the Muppets, Henson's contributions to Sesame Street and Saturday Night Live, and his nearly ten year campaign to bring The Muppet Show to television. Jones provides the imaginative context for Henson's non-Muppet projects, including the richly imagined worlds of The Dark Crystal and Labyrinth-as well as fascinating misfires like Henson's dream of opening an inflatable psychedelic nightclub or of staging an elaborate, all-puppet Broadway show.An uncommonly intimate portrait, Jim Henson captures all the facets of this American original: the master craftsman who revolutionized the presentation of puppets on television, the savvy businessman whose deal making prowess won him a reputation as "the new Walt Disney," and the creative team leader whose collaborative ethos earned him the undying loyalty of everyone who worked for him. Here also is insight into Henson's intensely private personal life: his Christian Science upbringing; his love of fast cars, high-stakes gambling, and expensive art; and his weakness for women. Though an optimist by nature, Henson was haunted by the notion that he would not have time to do all the things he wanted to do in life-a fear that his heartbreaking final hours would prove all too well-founded.An up-close look at the charmed life of a legend, Jim Henson gives the full measure to a man whose joyful genius transcended age, language, geography, and culture-and continues to beguile audiences worldwide.

    Molly wanted nothing more than to bask in that glow a little herself, so she pushed herself too—as a student, as an athlete. She was successful but felt like she was always coming from behind. She wanted to break free, to find a life without rules and limits, a life where she didn't have to measure up to anyone or anything—where she could become whatever she wanted.Molly wanted more, and she got more than she could have ever bargained for.In Molly's Game, Molly Bloom takes the reader through her adventures running an exclusive high-stakes private poker game. Her clients ranged from iconic stars like Leonardo DiCaprio and Ben Affleck to politicians and financial titans so powerful they moved markets and changed the course of history. With rich detail, Molly describes a world that until now has been shrouded in glamour, privilege, and secrecy, one where she fearlessly took on the Russian and Italian mobs—until she met the one adversary she could not outsmart, even though she had justice on her side: the United States government.Molly's Game is an incredible coming-of-age story about a young girl who rejected convention in pursuit of her version of the American dream. It's the story of how she gained—and then lost—her place at the table, and of everything she learned about poker, love, and life in the process.

    The episode unnerved him, but forced him to reflect on his life so far. This is the framework for his hilarious and moving memoir, And Away...Although his childhood in Middlesbrough was normal on the surface, it was tinged by the loss of his dad, and his own various misadventures (now infamous from his appearances on Would I Lie to You?), from burning down the family home to starting a short-lived punk band called Dog Dirt. As an adult, he trained as a solicitor and moved to London. Though he was doing pretty well (the South London Press once crowned him 'The Cockroach King' after a successful verdict), a chance encounter in a pub in the 1980s with a young comedian going by the name Vic Reeves set his life on a different track. And now, six years on, the heart condition that once threatened his career has instead led to new success on BBC2's Gone Fishing.Warm, profound, and irrepressibly funny, And Away... is Bob's full life story (with a few lies thrown in for good measure).

    Forrest Griffin is the light-heavyweight champion of the Ultimate Fighting Championship (UFC) and was the winner of the first season of Spike TV’s The Ultimate Fighter; in Got Fight?, he shows you how he did it. With Erich Krauss, Muay Thai fighter and co-author of “The Prodigy” B.J. Penn’s Mixed Martial Arts: The Book of Knowledge.

    But through self-discipline, mental toughness, and hard work, Goggins transformed himself from a depressed, overweight young man with no future into a U.S. Armed Forces icon and one of the world's top endurance athletes. The only man in history to complete elite training as a Navy SEAL, Army Ranger, and Air Force Tactical Air Controller, he went on to set records in numerous endurance events, inspiring Outside magazine to name him "The Fittest (Real) Man in America."In Can't Hurt Me, he shares his astonishing life story and reveals that most of us tap into only 40% of our capabilities. Goggins calls this The 40% Rule, and his story illuminates a path that anyone can follow to push past pain, demolish fear, and reach their full potential.

    Each regionally-based promotion operated individually and offered a brand of localized wrestling that greatly appealed to area fans. Promoters routinely coordinated with associates in surrounding regions, and the cooperation displayed by members of the National Wrestling Alliance made it easy for wrestlers to traverse the landscape with the utmost freedom. Dozens of territories flourished between the 1950s and late ’70s. But by the early 1980s, the growth of cable television had put new outside pressures on promoters. An enterprising third-generation entrepreneur who believed cable was his opportunity to take his promotion national soon capitalized on the situation.A host of novel ideas and the will to take chances gave Vincent Kennedy McMahon an incredible advantage. McMahon waged war on the territories and raided the NWA and AWA of their top talent. By creating WrestleMania, jumping into the pay-per-view field, and expanding across North America, McMahon changed professional wrestling forever.Providing never-before-revealed information, Death of the Territories is a must-read for fans yearning to understand how McMahon outlasted his rivals and established the industry’s first national promotion. At the same time, it offers a comprehensive look at the promoters who opposed McMahon, focusing on their noteworthy power plays and embarrassing mistakes.

    Until one day they all flood back in horrible detail.When television producers approached Alan Cumming to appear on a popular celebrity genealogy show, he hoped to solve the mystery of his maternal grandfather's disappearance that had long cast a shadow over his family. But this was not the only mystery laid before Alan.Alan grew up in the grip of a man who held his family hostage, someone who meted out violence with a frightening ease, who waged a silent war with himself that sometimes spilled over onto everyone around him. That man was Alex Cumming, Alan's father, whom Alan had not seen or spoken to for more than a decade when he reconnected just before filming for Who Do You Think You Are? began. He had a secret he had to share, one that would shock his son to his very core and set into motion a journey that would change Alan's life forever.With ribald humor, wit, and incredible insight, Alan seamlessly moves back and forth in time, integrating stories from his childhood in Scotland and his experiences today as the celebrated actor of film, television, and stage. At times suspenseful, at times deeply moving, but always incredibly brave and honest, Not My Father's Son is a powerful story of embracing the best aspects of the past and triumphantly pushing the darkness aside.

    With his trademark wit and heart, he outlines the absurdities and challenges that come with growing old, from insomnia to memory loss to leaving dinners with half your meal on your shirt. In humorous chapters like “Buying the Plot” and “Nodding Off,” Crystal not only catalogues his physical gripes, but offers a road map to his 77 million fellow baby boomers who are arriving at this milestone age with him. He also looks back at the most powerful and memorable moments of his long and storied life, from entertaining his relatives as a kid in Long Beach, Long Island, his years doing stand-up in the Village, up through his legendary stint at Saturday Night Live, When Harry Met Sally, and his long run as host of the Academy Awards. Readers get a front-row seat to his one-day career with the New York Yankees (he was the first player to ever “test positive for Maalox”), his love affair with Sophia Loren, and his enduring friendships with several of his idols, including Mickey Mantle and Muhammad Ali. He lends a light touch to more serious topics like religion (“the aging friends I know have turned to the Holy Trinity: Advil, bourbon, and Prozac”), grandparenting, and, of course, dentistry. As wise and poignant as they are funny, Crystal’s reflections are an unforgettable look at an extraordinary life well lived.

    It wasn’t drugs, alcohol, or sex: it was film. After moving to Los Angeles, Oswalt became a huge film buff (or as he calls it, a sprocket fiend), absorbing classics, cult hits, and new releases at the famous New Beverly Cinema. Silver screen celluloid became Patton’s life schoolbook, informing his notion of acting, writing, comedy, and relationships.Set in the nascent days of LA’s alternative comedy scene, Silver Screen Fiend chronicles Oswalt’s journey from fledgling stand-up comedian to self-assured sitcom actor, with the colorful New Beverly collective and a cast of now-notable young comedians supporting him all along the way.

    He's an actor, film star, trained undertaker, unlikely diplomat, secret romantic, martial artist and mountaineer. He's also a brilliant storyteller who will - and you must brace yourself - simply leap out of the pages at you. Ready? Then open Absolute Pandemonium and you'll be taken on a riotous journey from his childhood, growing up the son of a miner in Goldthorpe, to finding fame in Z-Cars. You'll see Brian falling for Katharine Hepburn on the set of The Trojan Women, suffering wires strapped round his wotsits as he was hoisted into the heavens on Flash Gordon, almost causing an international incident when meeting the Emperor and Empress of Japan, and winning round George Lucas to get the role of Boss Nass on Star Wars Episode I: The Phantom Menace.Along the way he takes secret revenge on headmistress Mrs Jarman and her very big bottom, punches Harold Pinter, loves and hates Peter O'Toole, woos his beautiful wife Hildegard Neil and braves the shocking death toll on cosy TV drama My Family and Other Animals. Crammed with anecdotes from his illustrious career, this is a funny, warm-hearted, life-affirming, LOUD and unique memoir from a much-loved figure.

    Millions of Vanderpump Rules viewers and podcast listeners know Stassi Schroeder as a major defender of Basic Bitch rights. There’s nothing more boring than people who take themselves too seriously or think that you have to be pretentious to be cool. Stassi champions the things that many of us are afraid to love publicly for fear of being labeled basic: lattes, pugs, bubbly cocktails, millennial pink, #OOTD (outfit of the day, obvs), astrology, hot dogs, the perfect pair of Louboutins, romantic comedies...the list goes on and on. This book is for people tired of pretending they would rather see a Daniel Day-Lewis movie about sewing or read War and Peace than watch a Saw marathon or read...well, this book! In Next Level Basic, the reality star, podcast queen, and ranch dressing expert gives you hilarious and pointed lessons on how to have fun and celebrate yourself, with exclusive stories from her own life and on the set of Vanderpump Rules. From her very public breakups to her most intimate details about her plastic surgery, Stassi shares her own personal experiences with her trademark honesty—all with the hope you can learn something from them.

    He wound up starring as Oscar Wilde in the film Wilde, costarring in A Civil Action, and writing funny, distinguished novels. This irresistible book, the best-written celebrity memoir of 1999, concentrates on Fry's first two tumultuous decades, but beware! A Fry sentence can lead anywhere, from a ringing defense of beating schoolchildren to a thoughtful comparison of male and female naughty parts. Fry's deepest regrets seem to be the elusiveness of a particular boy's love and the fact that, despite his keen ear for music, Fry's singing voice can make listeners "claw out their inner ears, electrocute their genitals, put on a Jim Reeves record, throw themselves cackling hysterically onto the path of moving buses... anything, anything to take away the pain." A chance mention of Fry's time-travel book about thwarting Hitler, Making History (a finalist for the 1998 Sidewise Award for Best Alternative History), leads to the startling real-life revelation that Fry's own Jewish uncle may have loaned a young, shivering Hitler the coat off his back. Fry's life is full of school and jailhouse blues overcome by jaunty wit, à la Wilde. The title, from Psalm 108:9, refers to King David's triumph over the Philistines. Fry triumphs similarly, and with more style. --Tim Appelo

    Those basset-hound eyes. That bone-dry wit. There has never been another comedian like Bob Newhart. His comedy albums, movies, and two hit television series have made him a national treasure and placed him firmly in the pantheon of comedy legends. Who else has a drinking game named after him And now, at last, Newhart puts his brilliant and hysterical world view on paper. Never a punch-line comic, always more of a storyteller, he tells anecdotes from throughout his life and career, including his beginnings as an accountant and the groundbreaking success of his comedy albums and The Bob Newhart Show and Newhart, which gave him fifteen years on primetime television. And he also gives his wry, comedic twist to a multitude of topics, including golf, drinking, and family holidays. Today, Newhart appears on Desperate Housewives, in hit movies such as Elf, and in theaters around the country. Reruns of his shows air constantly on Nick at Nite -- have recently been released with great success for the first time ever on DVD. With this book, Bob Newhart gives his millions of fans a first ever opportunity to sample his unique brand of humor -- including excerpts from some of his classic routines -- on the printed page.

    Now I’m letting my guard down.” —Hillary Rodham Clinton, from the introduction of What HappenedFor the first time, Hillary Rodham Clinton reveals what she was thinking and feeling during one of the most controversial and unpredictable presidential elections in history. Now free from the constraints of running, Hillary takes you inside the intense personal experience of becoming the first woman nominated for president by a major party in an election marked by rage, sexism, exhilarating highs and infuriating lows, stranger-than-fiction twists, Russian interference, and an opponent who broke all the rules. This is her most personal memoir yet. In these pages, she describes what it was like to run against Donald Trump, the mistakes she made, how she has coped with a shocking and devastating loss, and how she found the strength to pick herself back up afterward. With humor and candor, she tells readers what it took to get back on her feet—the rituals, relationships, and reading that got her through, and what the experience has taught her about life. She speaks about the challenges of being a strong woman in the public eye, the criticism over her voice, age, and appearance, and the double standard confronting women in politics. She lays out how the 2016 election was marked by an unprecedented assault on our democracy by a foreign adversary. By analyzing the evidence and connecting the dots, Hillary shows just how dangerous the forces are that shaped the outcome, and why Americans need to understand them to protect our values and our democracy in the future. The election of 2016 was unprecedented and historic. What Happened is the story of that campaign and its aftermath—both a deeply intimate account and a cautionary tale for the nation.